CA2870179C - Vaccines and methods to treat lyme disease in dogs - Google Patents

Vaccines and methods to treat lyme disease in dogs Download PDF

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Publication number
CA2870179C
CA2870179C CA2870179A CA2870179A CA2870179C CA 2870179 C CA2870179 C CA 2870179C CA 2870179 A CA2870179 A CA 2870179A CA 2870179 A CA2870179 A CA 2870179A CA 2870179 C CA2870179 C CA 2870179C
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CA
Canada
Prior art keywords
seq
construct
peptide
loop
immunogenic composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA2870179A
Other languages
English (en)
French (fr)
Other versions
CA2870179A1 (en
Inventor
Robert M. LOHSE
Patrick F. M. Meeus
Jason J. MILLERSHIP
Zach XU
Richard Thomas Marconi
Christopher Earnhart
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Virginia Commonwealth University
Zoetis Services LLC
Original Assignee
Virginia Commonwealth University
Zoetis Services LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Virginia Commonwealth University, Zoetis Services LLC filed Critical Virginia Commonwealth University
Publication of CA2870179A1 publication Critical patent/CA2870179A1/en
Application granted granted Critical
Publication of CA2870179C publication Critical patent/CA2870179C/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/0225Spirochetes, e.g. Treponema, Leptospira, Borrelia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/55Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552Veterinary vaccine
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CA2870179A 2012-04-18 2013-04-18 Vaccines and methods to treat lyme disease in dogs Active CA2870179C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261635031P 2012-04-18 2012-04-18
US61/635,031 2012-04-18
PCT/US2013/037063 WO2013158818A2 (en) 2012-04-18 2013-04-18 Vaccines and methods to treat lyme disease in dogs

Publications (2)

Publication Number Publication Date
CA2870179A1 CA2870179A1 (en) 2013-10-24
CA2870179C true CA2870179C (en) 2018-09-04

Family

ID=48193279

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2870179A Active CA2870179C (en) 2012-04-18 2013-04-18 Vaccines and methods to treat lyme disease in dogs

Country Status (10)

Country Link
EP (1) EP2838555A2 (es)
JP (1) JP2015514776A (es)
CN (1) CN104379164A (es)
AR (1) AR090726A1 (es)
AU (1) AU2013249229A1 (es)
BR (1) BR112014025740A2 (es)
CA (1) CA2870179C (es)
EA (1) EA201491668A1 (es)
UY (1) UY34745A (es)
WO (1) WO2013158818A2 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3204404A4 (en) 2014-10-08 2018-06-06 Virginia Commonwealth University Stage specific diagnostic antigens, assay and vaccine for lyme disease
JP2021505560A (ja) * 2017-12-04 2021-02-18 インターベット インターナショナル ベー. フェー. イヌライム病ワクチン
CN110483624B (zh) * 2019-08-22 2021-02-09 中国疾病预防控制中心传染病预防控制所 伽氏疏螺旋体OspA蛋白C端肽段及其应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4567043A (en) 1983-06-15 1986-01-28 American Home Products Corporation (Del.) Canine corona virus vaccine
US4567042A (en) 1983-06-15 1986-01-28 American Home Products Corporation Inactivated canine coronavirus vaccine
US6872550B1 (en) 1991-07-11 2005-03-29 Baxter Vaccine Ag Immunogenic formulation of OspC antigen vaccines for the prevention and treatment of lyme disease and recombinant methods for the preparation of such antigens
CA2115554A1 (en) * 1991-08-15 1993-03-04 Yves Lobet Osp a proteins of borrelia burgdorferi subgroups, encoding genes and vaccines
WO2000006745A1 (en) 1998-07-31 2000-02-10 Gundersen Lutheran Medical Foundation, Inc. Uses of the borreliacidal epitope(s) of borrelia burgdorferi outer surface protein c (ospc) as vaccine
EP2283031B1 (en) * 2008-05-02 2017-04-12 Virginia Commonwealth University Lyme disease vaccine
WO2010132758A2 (en) * 2009-05-14 2010-11-18 Gomes-Solecki Maria J Ospc-based diagnostic test for lyme disease
EP3029073B1 (en) * 2010-10-20 2019-09-04 Virginia Commonwealth University Polyvalent chimeric ospc vaccinogen and diagnostic antigen

Also Published As

Publication number Publication date
WO2013158818A2 (en) 2013-10-24
CA2870179A1 (en) 2013-10-24
EA201491668A1 (ru) 2015-08-31
AR090726A1 (es) 2014-12-03
UY34745A (es) 2013-11-29
EP2838555A2 (en) 2015-02-25
BR112014025740A2 (pt) 2017-07-04
AU2013249229A1 (en) 2014-10-23
JP2015514776A (ja) 2015-05-21
WO2013158818A3 (en) 2014-04-17
CN104379164A (zh) 2015-02-25

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