CA2868403A1 - Treatment of postpartum haemorrhage with chemically modified heparin or heparan sulphate and a uterotonic agent - Google Patents

Treatment of postpartum haemorrhage with chemically modified heparin or heparan sulphate and a uterotonic agent Download PDF

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Publication number
CA2868403A1
CA2868403A1 CA2868403A CA2868403A CA2868403A1 CA 2868403 A1 CA2868403 A1 CA 2868403A1 CA 2868403 A CA2868403 A CA 2868403A CA 2868403 A CA2868403 A CA 2868403A CA 2868403 A1 CA2868403 A1 CA 2868403A1
Authority
CA
Canada
Prior art keywords
chemically modified
heparan sulfate
modified heparin
heparin
use according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2868403A
Other languages
English (en)
French (fr)
Inventor
Gunvor Ekman-Ordeberg
Anders Malmstrom
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dilafor AB
Original Assignee
Dilafor AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dilafor AB filed Critical Dilafor AB
Publication of CA2868403A1 publication Critical patent/CA2868403A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/727—Heparin; Heparan
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/48—Ergoline derivatives, e.g. lysergic acid, ergotamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • A61K31/5575—Eicosanoids, e.g. leukotrienes or prostaglandins having a cyclopentane, e.g. prostaglandin E2, prostaglandin F2-alpha
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A61K38/095—Oxytocins; Vasopressins; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/04—Drugs for genital or sexual disorders; Contraceptives for inducing labour or abortion; Uterotonics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pregnancy & Childbirth (AREA)
  • Gynecology & Obstetrics (AREA)
  • Diabetes (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CA2868403A 2012-05-08 2013-05-07 Treatment of postpartum haemorrhage with chemically modified heparin or heparan sulphate and a uterotonic agent Abandoned CA2868403A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201261644036P 2012-05-08 2012-05-08
US61/644,036 2012-05-08
US201261668150P 2012-07-05 2012-07-05
US61/668,150 2012-07-05
PCT/SE2013/050510 WO2013169194A1 (en) 2012-05-08 2013-05-07 Treatment of postpartum haemorrhage with chemically modified heparin or heparan sulphate and a uterotonic agent

Publications (1)

Publication Number Publication Date
CA2868403A1 true CA2868403A1 (en) 2013-11-14

Family

ID=49551063

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2868403A Abandoned CA2868403A1 (en) 2012-05-08 2013-05-07 Treatment of postpartum haemorrhage with chemically modified heparin or heparan sulphate and a uterotonic agent

Country Status (16)

Country Link
US (1) US20150099703A1 (enExample)
EP (1) EP2846810A4 (enExample)
JP (1) JP2015516415A (enExample)
CN (1) CN104284667A (enExample)
AU (1) AU2013260209A1 (enExample)
BR (1) BR112014027712B1 (enExample)
CA (1) CA2868403A1 (enExample)
HK (1) HK1203377A1 (enExample)
IL (1) IL234752A0 (enExample)
MX (1) MX2014013449A (enExample)
MY (1) MY192330A (enExample)
NZ (1) NZ701419A (enExample)
RU (1) RU2014149230A (enExample)
SG (1) SG11201407346WA (enExample)
UA (1) UA117912C2 (enExample)
WO (1) WO2013169194A1 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12502403B2 (en) 2020-02-17 2025-12-23 Dilafor Ab Tafoxiparin for the treatment of preeclampsia
CA3255831A1 (en) 2022-05-03 2023-11-09 Dilafor Ab NEW MEDICAL USE OF TAFOXIPARIN
EP4272749A1 (en) 2022-05-03 2023-11-08 Dilafor AB New medical use of tafoxiparin

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5993810A (en) * 1996-03-15 1999-11-30 Lebovitz; Shamir Israel Method of softening or ripening the cervix of a female mammal using collagenase
SE521676C2 (sv) * 2002-01-02 2003-11-25 Dilafor Ab Användning av glykosaminoglykaner för prevention och behandling av värksvaghet vid fullgången graviditet
US8071569B2 (en) * 2002-09-20 2011-12-06 Mousa Shaker A Oxidized heparin fractions and their use in inhibiting angiogenesis
UA21707U (en) * 2006-12-18 2007-03-15 Valerii Ivanovych Linnikov Method for preventing and treating thrombophilia in course of gestation and postpartum
US8445436B2 (en) * 2007-12-03 2013-05-21 Florida State University Research Foundation, Inc. Oxytocin and melatonin compositions and associated methods for inducing labor
JO3400B1 (ar) * 2010-09-30 2019-10-20 Ferring Bv مركب صيدلاني من كاربيتوسين
DK2794665T3 (da) * 2011-12-19 2018-01-29 Dilafor Ab Ikke-antikoagulative glycosaminoglycaner omfattende disaccharid-gentagelsesenhed og medicinsk anvendelse deraf
CN104203256B (zh) * 2012-03-26 2017-11-24 迪乐方有限责任公司 用于引产的包含硫酸化的葡糖胺聚糖的联合治疗
NZ631279A (en) * 2012-03-26 2016-06-24 Dilafor Ab Method for treatment of labor arrest

Also Published As

Publication number Publication date
RU2014149230A (ru) 2016-06-27
AU2013260209A1 (en) 2014-11-20
MX2014013449A (es) 2014-12-08
CN104284667A (zh) 2015-01-14
JP2015516415A (ja) 2015-06-11
WO2013169194A1 (en) 2013-11-14
UA117912C2 (uk) 2018-10-25
US20150099703A1 (en) 2015-04-09
NZ701419A (en) 2016-04-29
SG11201407346WA (en) 2014-12-30
HK1203377A1 (en) 2015-10-30
EP2846810A1 (en) 2015-03-18
IL234752A0 (en) 2014-11-30
MY192330A (en) 2022-08-17
BR112014027712A2 (pt) 2017-06-27
BR112014027712B1 (pt) 2023-12-19
EP2846810A4 (en) 2016-04-13

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Legal Events

Date Code Title Description
FZDE Discontinued

Effective date: 20180510