CA2865312A1 - Taste masked dispersible tablets - Google Patents

Taste masked dispersible tablets Download PDF

Info

Publication number
CA2865312A1
CA2865312A1 CA2865312A CA2865312A CA2865312A1 CA 2865312 A1 CA2865312 A1 CA 2865312A1 CA 2865312 A CA2865312 A CA 2865312A CA 2865312 A CA2865312 A CA 2865312A CA 2865312 A1 CA2865312 A1 CA 2865312A1
Authority
CA
Canada
Prior art keywords
taste
exchange resin
cation exchange
drug
dispersible tablet
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2865312A
Other languages
English (en)
French (fr)
Inventor
Vinod Kumar Arora
Jatin Khurana
Deepak Gaikwad
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ranbaxy Laboratories Ltd
Original Assignee
Ranbaxy Laboratories Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ranbaxy Laboratories Ltd filed Critical Ranbaxy Laboratories Ltd
Publication of CA2865312A1 publication Critical patent/CA2865312A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/194—Carboxylic acids, e.g. valproic acid having two or more carboxyl groups, e.g. succinic, maleic or phthalic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/58—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. poly[meth]acrylate, polyacrylamide, polystyrene, polyvinylpyrrolidone, polyvinylalcohol or polystyrene sulfonic acid resin
    • A61K47/585—Ion exchange resins, e.g. polystyrene sulfonic acid resin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA2865312A 2012-02-21 2013-02-21 Taste masked dispersible tablets Abandoned CA2865312A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IN496/DEL/2012 2012-02-21
IN496DE2012 2012-02-21
PCT/IB2013/051432 WO2013124818A1 (en) 2012-02-21 2013-02-21 Taste masked dispersible tablets

Publications (1)

Publication Number Publication Date
CA2865312A1 true CA2865312A1 (en) 2013-08-29

Family

ID=54261187

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2865312A Abandoned CA2865312A1 (en) 2012-02-21 2013-02-21 Taste masked dispersible tablets

Country Status (10)

Country Link
US (1) US20150031647A1 (enExample)
EP (1) EP2816997A1 (enExample)
CN (1) CN104203212A (enExample)
AP (1) AP2014007934A0 (enExample)
AU (1) AU2013223705A1 (enExample)
CA (1) CA2865312A1 (enExample)
IN (1) IN2014DN07895A (enExample)
MX (1) MX2014010038A (enExample)
SG (1) SG11201405053SA (enExample)
WO (1) WO2013124818A1 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6577024B2 (ja) * 2014-05-08 2019-09-18 シーティーシー バイオ インコーポレイテッド 味が遮蔽されたクロミプラミン含有経口投与用薬学製剤
CN112353802A (zh) * 2020-11-26 2021-02-12 山东诚创蓝海医药科技有限公司 一种富马酸伏诺拉生掩味组合物及其应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020032245A1 (en) 2000-07-27 2002-03-14 Lyn Hughes Resinate composition
US20040067216A1 (en) 2002-02-22 2004-04-08 Karki Shyam B. Hiv protease inhibitors supported on cation exchange resins for oral administration
EP2198857A1 (en) * 2008-12-19 2010-06-23 Ratiopharm GmbH Oral dispersible tablet
EP2519264A1 (en) * 2009-12-31 2012-11-07 Ranbaxy Laboratories Limited Taste masked dosage forms of bitter tasting anti-retroviral drugs

Also Published As

Publication number Publication date
WO2013124818A1 (en) 2013-08-29
AP2014007934A0 (en) 2014-09-30
IN2014DN07895A (enExample) 2015-04-24
SG11201405053SA (en) 2014-09-26
CN104203212A (zh) 2014-12-10
AU2013223705A1 (en) 2014-09-11
EP2816997A1 (en) 2014-12-31
US20150031647A1 (en) 2015-01-29
MX2014010038A (es) 2014-12-05

Similar Documents

Publication Publication Date Title
JP4340840B2 (ja) 最小化ｐＨ依存性溶解プロフィールを有する徐放性薬学的剤形
CA2722093C (en) Pharmaceutical compositions comprising brivaracetam
RU2485947C2 (ru) Фармацевтические композиции энтакапона, леводопы и карбидопы с улучшенной биодоступностью
KR101801424B1 (ko) 날부핀-기재 제제 및 그것의 용도
AU2003209673B2 (en) Tasteless directly compressible fast-dissolving complexes and pharmaceutical formulations thereof
US20100226979A1 (en) Taste Masked Phamaceutical Composition for Oral Solid Dosage form and Process for Preparing the Same Using Magnesium Aluminium Silicate
EP2389070B1 (en) Disintegrable formulations of lanthanum carbonate
US4774083A (en) Novel pharmaceutical tablets
EP2595607A2 (de) Arzneimittel zur oralen verabreichung umfassend ein gemisch aus silodosin und einem basischen copolymer
AU2013223705A1 (en) Taste masked dispersible tablets
JP2008536922A (ja) オランザピンの医薬用経口崩壊錠
EP2593081B1 (en) Ferrimannitol-ovalbumin tablet composition
OA17084A (en) Taste masked dispersible tablets.
KR101124796B1 (ko) 도네페질 수지 착체
JP2000273037A (ja) 解熱・鎮痛チュアブル錠およびその製造法
JP2016503782A (ja) Ｎ−［５−［２−（３，５−ジメトキシフェニル）エチル］−２ｈ−ピラゾール−３−イル］−４−［（３ｒ，５ｓ）−３，５−ジメチルピペラジン−１−イル］ベンズアミドの医薬製剤
CN101185640B (zh) 氯诺昔康缓释片及其制备方法
DE602004010732T2 (de) Geschmacklose, direkt verpressbare, schnelllösliche Komplexe und ihre pharmazeutischen Zusammensetzungen.
CN112057427A (zh) 一种含有布鲁顿氏酪氨酸激酶抑制剂的口服固体片剂及其制备方法
WO2005016315A1 (en) Pharmaceutical compositions of nateglinide and a high amount of a water-soluble filler
JP2000344664A (ja) ビタミンｋを含有する口腔内崩壊型錠剤
JP2022545822A (ja) チダミド医薬組成物、その調製方法及びその適用
HK1163452B (en) Disintegrable formulations of lanthanum carbonate

Legal Events

Date Code Title Description
EEER Examination request

Effective date: 20140821

FZDE Discontinued

Effective date: 20160223