CA2865020C - Pharmaceutical composition for treatment and/or prevention of cancer - Google Patents

Pharmaceutical composition for treatment and/or prevention of cancer Download PDF

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Publication number
CA2865020C
CA2865020C CA2865020A CA2865020A CA2865020C CA 2865020 C CA2865020 C CA 2865020C CA 2865020 A CA2865020 A CA 2865020A CA 2865020 A CA2865020 A CA 2865020A CA 2865020 C CA2865020 C CA 2865020C
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CA
Canada
Prior art keywords
antibody
cancer
caprin
seq
fragment
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Active
Application number
CA2865020A
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English (en)
French (fr)
Other versions
CA2865020A1 (en
Inventor
Shinichi Kobayashi
Fumiyoshi Okano
Takanori Saito
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Toray Industries Inc
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Toray Industries Inc
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Publication of CA2865020A1 publication Critical patent/CA2865020A1/en
Application granted granted Critical
Publication of CA2865020C publication Critical patent/CA2865020C/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
    • C07K2317/14—Specific host cells or culture conditions, e.g. components, pH or temperature
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C07K2317/732—Antibody-dependent cellular cytotoxicity [ADCC]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
CA2865020A 2012-02-21 2013-02-21 Pharmaceutical composition for treatment and/or prevention of cancer Active CA2865020C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2012035491 2012-02-21
JP2012-035491 2012-02-21
PCT/JP2013/054345 WO2013125640A1 (ja) 2012-02-21 2013-02-21 癌の治療及び／又は予防用医薬組成物

Publications (2)

Publication Number Publication Date
CA2865020A1 CA2865020A1 (en) 2013-08-29
CA2865020C true CA2865020C (en) 2021-01-26

Family

ID=49005817

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2865020A Active CA2865020C (en) 2012-02-21 2013-02-21 Pharmaceutical composition for treatment and/or prevention of cancer

Country Status (17)

Country Link
US (1) US9266958B2 (ref)
EP (1) EP2824114B1 (ref)
JP (1) JP6187258B2 (ref)
KR (1) KR102009236B1 (ref)
CN (1) CN104114583B (ref)
AU (1) AU2013223147B2 (ref)
BR (1) BR112014021103A2 (ref)
CA (1) CA2865020C (ref)
DK (1) DK2824114T3 (ref)
ES (1) ES2739380T3 (ref)
HU (1) HUE045461T2 (ref)
IN (1) IN2014KN01716A (ref)
MX (1) MX360211B (ref)
PL (1) PL2824114T3 (ref)
PT (1) PT2824114T (ref)
RU (1) RU2633505C2 (ref)
WO (1) WO2013125640A1 (ref)

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WO2023008459A1 (ja) 2021-07-27 2023-02-02 東レ株式会社 癌の治療及び／又は予防のための医薬品
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CN104114583B (zh) 2019-11-19
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PT2824114T (pt) 2019-08-05
US9266958B2 (en) 2016-02-23
EP2824114A4 (en) 2015-10-07
BR112014021103A8 (pt) 2018-01-23
JP6187258B2 (ja) 2017-08-30
RU2014138038A (ru) 2016-04-10
DK2824114T3 (da) 2019-07-29
KR102009236B1 (ko) 2019-08-09
RU2633505C2 (ru) 2017-10-12
US20150017172A1 (en) 2015-01-15
AU2013223147B2 (en) 2017-10-05
PL2824114T3 (pl) 2019-11-29
EP2824114A1 (en) 2015-01-14
ES2739380T3 (es) 2020-01-30
BR112014021103A2 (pt) 2019-10-15
MX2014009749A (es) 2014-11-14
IN2014KN01716A (ref) 2015-10-23
MX360211B (es) 2018-10-24
AU2013223147A1 (en) 2014-09-11
EP2824114B1 (en) 2019-05-22
WO2013125640A1 (ja) 2013-08-29
HUE045461T2 (hu) 2019-12-30
CN104114583A (zh) 2014-10-22

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