CA2865020C - Pharmaceutical composition for treatment and/or prevention of cancer - Google Patents

Pharmaceutical composition for treatment and/or prevention of cancer Download PDF

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Publication number
CA2865020C
CA2865020C CA2865020A CA2865020A CA2865020C CA 2865020 C CA2865020 C CA 2865020C CA 2865020 A CA2865020 A CA 2865020A CA 2865020 A CA2865020 A CA 2865020A CA 2865020 C CA2865020 C CA 2865020C
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CA
Canada
Prior art keywords
antibody
cancer
caprin
seq
fragment
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CA2865020A
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English (en)
French (fr)
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CA2865020A1 (en
Inventor
Shinichi Kobayashi
Fumiyoshi Okano
Takanori Saito
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Toray Industries Inc
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Toray Industries Inc
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Publication of CA2865020A1 publication Critical patent/CA2865020A1/en
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Active legal-status Critical Current
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/10Immunoglobulins specific features characterized by their source of isolation or production
    • C07K2317/14Specific host cells or culture conditions, e.g. components, pH or temperature
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C07K2317/732Antibody-dependent cellular cytotoxicity [ADCC]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Endocrinology (AREA)
  • Mycology (AREA)
  • Cell Biology (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
CA2865020A 2012-02-21 2013-02-21 Pharmaceutical composition for treatment and/or prevention of cancer Active CA2865020C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2012-035491 2012-02-21
JP2012035491 2012-02-21
PCT/JP2013/054345 WO2013125640A1 (ja) 2012-02-21 2013-02-21 癌の治療及び/又は予防用医薬組成物

Publications (2)

Publication Number Publication Date
CA2865020A1 CA2865020A1 (en) 2013-08-29
CA2865020C true CA2865020C (en) 2021-01-26

Family

ID=49005817

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2865020A Active CA2865020C (en) 2012-02-21 2013-02-21 Pharmaceutical composition for treatment and/or prevention of cancer

Country Status (17)

Country Link
US (1) US9266958B2 (en:Method)
EP (1) EP2824114B1 (en:Method)
JP (1) JP6187258B2 (en:Method)
KR (1) KR102009236B1 (en:Method)
CN (1) CN104114583B (en:Method)
AU (1) AU2013223147B2 (en:Method)
BR (1) BR112014021103A2 (en:Method)
CA (1) CA2865020C (en:Method)
DK (1) DK2824114T3 (en:Method)
ES (1) ES2739380T3 (en:Method)
HU (1) HUE045461T2 (en:Method)
IN (1) IN2014KN01716A (en:Method)
MX (1) MX360211B (en:Method)
PL (1) PL2824114T3 (en:Method)
PT (1) PT2824114T (en:Method)
RU (1) RU2633505C2 (en:Method)
WO (1) WO2013125640A1 (en:Method)

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JP6187258B2 (ja) 2017-08-30
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BR112014021103A8 (pt) 2018-01-23
PT2824114T (pt) 2019-08-05
MX2014009749A (es) 2014-11-14
KR20140130671A (ko) 2014-11-11
DK2824114T3 (da) 2019-07-29
ES2739380T3 (es) 2020-01-30
CN104114583B (zh) 2019-11-19
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AU2013223147B2 (en) 2017-10-05
KR102009236B1 (ko) 2019-08-09
US9266958B2 (en) 2016-02-23
WO2013125640A1 (ja) 2013-08-29
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AU2013223147A1 (en) 2014-09-11
MX360211B (es) 2018-10-24
EP2824114A1 (en) 2015-01-14
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CN104114583A (zh) 2014-10-22
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