CA2864999C - Pharmaceutical composition for treatment and/or prevention of cancer - Google Patents

Pharmaceutical composition for treatment and/or prevention of cancer Download PDF

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Publication number
CA2864999C
CA2864999C CA2864999A CA2864999A CA2864999C CA 2864999 C CA2864999 C CA 2864999C CA 2864999 A CA2864999 A CA 2864999A CA 2864999 A CA2864999 A CA 2864999A CA 2864999 C CA2864999 C CA 2864999C
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Prior art keywords
antibody
cancer
ser
gin
pro
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CA2864999A
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English (en)
French (fr)
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CA2864999A1 (en
Inventor
Shinichi Kobayashi
Fumiyoshi Okano
Takanori Saito
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Toray Industries Inc
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Toray Industries Inc
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3015Breast
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/31Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C07K2317/732Antibody-dependent cellular cytotoxicity [ADCC]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CA2864999A 2012-02-21 2013-02-21 Pharmaceutical composition for treatment and/or prevention of cancer Active CA2864999C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2012-035342 2012-02-21
JP2012035342 2012-02-21
PCT/JP2013/054312 WO2013125630A1 (ja) 2012-02-21 2013-02-21 癌の治療及び/又は予防用医薬組成物

Publications (2)

Publication Number Publication Date
CA2864999A1 CA2864999A1 (en) 2013-08-29
CA2864999C true CA2864999C (en) 2020-06-30

Family

ID=49005808

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2864999A Active CA2864999C (en) 2012-02-21 2013-02-21 Pharmaceutical composition for treatment and/or prevention of cancer

Country Status (17)

Country Link
US (1) US9260513B2 (show.php)
EP (1) EP2818481B1 (show.php)
JP (1) JP6187257B2 (show.php)
KR (1) KR102005308B1 (show.php)
CN (1) CN104114581B (show.php)
AU (1) AU2013223137B2 (show.php)
BR (1) BR112014021099A2 (show.php)
CA (1) CA2864999C (show.php)
DK (1) DK2818481T3 (show.php)
ES (1) ES2749672T3 (show.php)
HU (1) HUE046788T2 (show.php)
IN (1) IN2014KN01714A (show.php)
MX (1) MX363136B (show.php)
PL (1) PL2818481T3 (show.php)
PT (1) PT2818481T (show.php)
RU (1) RU2639522C2 (show.php)
WO (1) WO2013125630A1 (show.php)

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RU2631804C2 (ru) 2012-02-21 2017-09-26 Торэй Индастриз, Инк. Фармацевтическая композиция для лечения или профилактики рака
ES2656620T3 (es) * 2012-03-30 2018-02-27 Toray Industries, Inc. Composición farmacéutica para el tratamiento y/o la prevención del cáncer de hígado
RU2649802C2 (ru) 2012-03-30 2018-04-04 Торэй Индастриз, Инк. Фармацевтическая композиция для лечения и/или предотвращения рака желчного пузыря
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WO2022270524A1 (ja) 2021-06-23 2022-12-29 東レ株式会社 癌の治療及び/又は予防のための医薬品
KR20240024074A (ko) 2021-06-23 2024-02-23 도레이 카부시키가이샤 암의 치료 및/또는 예방을 위한 의약품
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AU2022319362A1 (en) 2021-07-27 2024-02-29 Toray Industries, Inc. Medicament for treatment and/or prevention of cancer
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WO2024005123A1 (ja) 2022-06-30 2024-01-04 東レ株式会社 癌の治療及び/又は予防用医薬組成物
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MX363136B (es) 2019-03-12
KR20140130670A (ko) 2014-11-11
ES2749672T3 (es) 2020-03-23
IN2014KN01714A (show.php) 2015-10-23
EP2818481A1 (en) 2014-12-31
EP2818481B1 (en) 2019-08-07
PT2818481T (pt) 2019-10-25
US9260513B2 (en) 2016-02-16
MX2014009747A (es) 2014-11-14
KR102005308B1 (ko) 2019-07-30
WO2013125630A1 (ja) 2013-08-29
RU2014138039A (ru) 2016-04-10
EP2818481A4 (en) 2015-10-07
HUE046788T2 (hu) 2020-03-30
RU2639522C2 (ru) 2017-12-21
PL2818481T3 (pl) 2020-02-28
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CA2864999A1 (en) 2013-08-29
AU2013223137B2 (en) 2017-10-19
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AU2013223137A1 (en) 2014-09-11
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