CA2864999C - Pharmaceutical composition for treatment and/or prevention of cancer - Google Patents
Pharmaceutical composition for treatment and/or prevention of cancer Download PDFInfo
- Publication number
- CA2864999C CA2864999C CA2864999A CA2864999A CA2864999C CA 2864999 C CA2864999 C CA 2864999C CA 2864999 A CA2864999 A CA 2864999A CA 2864999 A CA2864999 A CA 2864999A CA 2864999 C CA2864999 C CA 2864999C
- Authority
- CA
- Canada
- Prior art keywords
- antibody
- cancer
- ser
- gin
- pro
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
- C07K16/3015—Breast
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
- C07K2317/732—Antibody-dependent cellular cytotoxicity [ADCC]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cell Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Endocrinology (AREA)
- Oncology (AREA)
- Hematology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2012-035342 | 2012-02-21 | ||
| JP2012035342 | 2012-02-21 | ||
| PCT/JP2013/054312 WO2013125630A1 (ja) | 2012-02-21 | 2013-02-21 | 癌の治療及び／又は予防用医薬組成物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2864999A1 CA2864999A1 (en) | 2013-08-29 |
| CA2864999C true CA2864999C (en) | 2020-06-30 |
Family
ID=49005808
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2864999A Active CA2864999C (en) | 2012-02-21 | 2013-02-21 | Pharmaceutical composition for treatment and/or prevention of cancer |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US9260513B2 (enExample) |
| EP (1) | EP2818481B1 (enExample) |
| JP (1) | JP6187257B2 (enExample) |
| KR (1) | KR102005308B1 (enExample) |
| CN (1) | CN104114581B (enExample) |
| AU (1) | AU2013223137B2 (enExample) |
| BR (1) | BR112014021099A2 (enExample) |
| CA (1) | CA2864999C (enExample) |
| DK (1) | DK2818481T3 (enExample) |
| ES (1) | ES2749672T3 (enExample) |
| HU (1) | HUE046788T2 (enExample) |
| IN (1) | IN2014KN01714A (enExample) |
| MX (1) | MX363136B (enExample) |
| PL (1) | PL2818481T3 (enExample) |
| PT (1) | PT2818481T (enExample) |
| RU (1) | RU2639522C2 (enExample) |
| WO (1) | WO2013125630A1 (enExample) |
Families Citing this family (45)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX337991B (es) | 2008-08-05 | 2016-03-30 | Toray Industries | Metodo para detectar cancer. |
| DK2322221T3 (da) | 2008-08-05 | 2014-09-01 | Toray Industries | Farmaceutisk sammensætning til behandling og forebyggelse af cancer |
| AU2011211699B2 (en) * | 2010-02-04 | 2015-01-22 | Toray Industries, Inc. | Pharmaceutical composition for treating and/or preventing cancer |
| BR112014002619A2 (pt) * | 2011-08-04 | 2018-10-09 | Toray Industries, Inc | composição farmacêutica e método de tratamento e/ou prevenção de câncer pancreático e combinação farmacêutica |
| ES2629061T3 (es) * | 2011-08-04 | 2017-08-07 | Toray Industries, Inc. | Método para la detección de cáncer pancreático |
| MX357505B (es) | 2012-02-21 | 2018-07-12 | Toray Industries | Composicion farmaceutica para el tratamiento y/o prevencion del cancer. |
| PT2832365T (pt) * | 2012-03-30 | 2018-01-24 | Toray Industries | Composição farmacêutica para o tratamento e/ou prevenção do cancro hepático |
| US9428581B2 (en) | 2012-03-30 | 2016-08-30 | Toray Industries, Inc. | Pharmaceutical composition for treatment and/or prevention of gallbladder cancer |
| WO2014014082A1 (ja) | 2012-07-19 | 2014-01-23 | 東レ株式会社 | 癌の検出方法 |
| CA2879185C (en) | 2012-07-19 | 2021-08-24 | Toray Industries, Inc. | Method for detecting cancer |
| CA2918989C (en) | 2013-08-09 | 2021-11-02 | Toray Industries, Inc. | Pharmaceutical composition for treatment and/or prevention of cancer |
| BR112019000071A2 (pt) | 2016-07-07 | 2019-07-02 | Bolt Biotherapeutics Inc | conjugados adjuvantes de anticorpo |
| WO2018079740A1 (ja) | 2016-10-28 | 2018-05-03 | 東レ株式会社 | 癌の治療及び／又は予防用医薬組成物 |
| WO2019189780A1 (ja) | 2018-03-30 | 2019-10-03 | 東レ株式会社 | 癌の治療及び／又は予防用医薬組成物 |
| EP3937984A1 (en) | 2019-03-15 | 2022-01-19 | Bolt Biotherapeutics, Inc. | Immunoconjugates targeting her2 |
| JP2022537158A (ja) | 2019-06-13 | 2022-08-24 | ボルト バイオセラピューティクス、インコーポレーテッド | アミノベンズアゼピン化合物、イムノコンジュゲート、及びそれらの使用 |
| EP4038053A1 (en) | 2019-09-30 | 2022-08-10 | Bolt Biotherapeutics, Inc. | Amide-linked, aminobenzazepine immunoconjugates, and uses thereof |
| EP4048315B1 (en) | 2019-10-25 | 2025-03-12 | Bolt Biotherapeutics, Inc. | Thienoazepine immunoconjugates, and uses thereof |
| JPWO2021182574A1 (enExample) * | 2020-03-12 | 2021-09-16 | ||
| EP4119157A4 (en) | 2020-03-12 | 2024-03-27 | Toray Industries, Inc. | MEDICINE FOR THE TREATMENT AND/OR PREVENTION OF CANCER |
| JP7797875B2 (ja) | 2020-03-12 | 2026-01-14 | 東レ株式会社 | 癌の治療及び／又は予防のための医薬品 |
| CA3175127A1 (en) * | 2020-03-12 | 2021-09-16 | Toray Industries, Inc. | Medicament for treatment and/or prevention of cancer |
| CA3175129A1 (en) | 2020-03-12 | 2021-09-19 | Toray Industries, Inc. | Medicament for treatment and/or prevention of cancer |
| CA3176626A1 (en) | 2020-05-08 | 2021-11-11 | David Dornan | Elastase-substrate, peptide linker immunoconjugates, and uses thereof |
| MX2023001679A (es) | 2020-08-13 | 2023-02-22 | Bolt Biotherapeutics Inc | Inmunoconjugados de pirazolazepina y usos de estos. |
| EP4360648A4 (en) | 2021-06-23 | 2025-10-08 | Toray Industries | MEDICINE FOR THE TREATMENT AND/OR PREVENTION OF CANCER |
| AU2022298240A1 (en) | 2021-06-23 | 2024-01-18 | Toray Industries, Inc. | Medicament for treatment and/or prevention of cancer |
| EP4378478A4 (en) | 2021-07-27 | 2025-11-12 | Toray Industries | MEDICINE FOR THE TREATMENT AND/OR PREVENTION OF CANCER |
| KR20240042415A (ko) | 2021-07-27 | 2024-04-02 | 도레이 카부시키가이샤 | 암의 치료 및/또는 예방을 위한 의약품 |
| AU2022319362A1 (en) | 2021-07-27 | 2024-02-29 | Toray Industries, Inc. | Medicament for treatment and/or prevention of cancer |
| CA3230737A1 (en) | 2021-09-03 | 2023-03-09 | Toray Industries, Inc. | Pharmaceutical composition for cancer treatment and/or prevention |
| US20250000995A1 (en) | 2021-10-29 | 2025-01-02 | Bolt Biotherapeutics, Inc. | Tlr agonist immunoconjugates with cysteine-mutant antibodies, and uses thereof |
| AU2023298568A1 (en) | 2022-06-30 | 2025-01-09 | Toray Industries, Inc. | Pharmaceutical composition for cancer treatment and/or prevention |
| AU2023329564A1 (en) | 2022-08-24 | 2025-02-27 | Toray Industries, Inc. | Medicament for treatment and/or prevention of cancer |
| CN119768181A (zh) | 2022-08-24 | 2025-04-04 | 东丽株式会社 | 用于癌的治疗和/或预防的药品 |
| JPWO2024043252A1 (enExample) | 2022-08-24 | 2024-02-29 | ||
| CN119789868A (zh) | 2022-08-30 | 2025-04-08 | 东丽株式会社 | 用于癌的治疗和/或预防的药品 |
| AU2023334696A1 (en) | 2022-08-30 | 2025-02-27 | Toray Industries, Inc. | Medicament for treatment and/or prevention of cancer |
| KR20250118852A (ko) | 2022-12-23 | 2025-08-06 | 도레이 카부시키가이샤 | 암의 치료 및/또는 예방을 위한 의약품 |
| WO2024173387A1 (en) | 2023-02-14 | 2024-08-22 | Bolt Biotherapeutics, Inc. | Aza-benzazepine immunoconjugates, and uses thereof |
| WO2024186626A1 (en) | 2023-03-03 | 2024-09-12 | Bolt Biotherapeutics, Inc. | Aza-bicyclic sting agonist immunoconjugates, and uses thereof |
| WO2024204325A1 (ja) | 2023-03-28 | 2024-10-03 | 東レ株式会社 | 細胞膜タンパク質を検出する方法 |
| EP4691490A1 (en) | 2023-03-31 | 2026-02-11 | Toray Industries, Inc. | Pharmaceutical composition for treating and/or preventing cancer |
| JPWO2025058000A1 (enExample) | 2023-09-13 | 2025-03-20 | ||
| WO2026055185A1 (en) | 2024-09-04 | 2026-03-12 | Bolt Biotherapeutics, Inc. | Sting agonist immunoconjugates and uses thereof |
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-
2013
- 2013-02-21 IN IN1714KON2014 patent/IN2014KN01714A/en unknown
- 2013-02-21 KR KR1020147020831A patent/KR102005308B1/ko active Active
- 2013-02-21 PT PT137511598T patent/PT2818481T/pt unknown
- 2013-02-21 MX MX2014009747A patent/MX363136B/es unknown
- 2013-02-21 BR BR112014021099-3A patent/BR112014021099A2/pt not_active Application Discontinuation
- 2013-02-21 PL PL13751159T patent/PL2818481T3/pl unknown
- 2013-02-21 CA CA2864999A patent/CA2864999C/en active Active
- 2013-02-21 DK DK13751159.8T patent/DK2818481T3/da active
- 2013-02-21 JP JP2013512279A patent/JP6187257B2/ja active Active
- 2013-02-21 RU RU2014138039A patent/RU2639522C2/ru active
- 2013-02-21 WO PCT/JP2013/054312 patent/WO2013125630A1/ja not_active Ceased
- 2013-02-21 AU AU2013223137A patent/AU2013223137B2/en active Active
- 2013-02-21 HU HUE13751159A patent/HUE046788T2/hu unknown
- 2013-02-21 CN CN201380009166.3A patent/CN104114581B/zh active Active
- 2013-02-21 EP EP13751159.8A patent/EP2818481B1/en active Active
- 2013-02-21 ES ES13751159T patent/ES2749672T3/es active Active
- 2013-02-21 US US14/379,868 patent/US9260513B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| RU2639522C2 (ru) | 2017-12-21 |
| PT2818481T (pt) | 2019-10-25 |
| AU2013223137A1 (en) | 2014-09-11 |
| RU2014138039A (ru) | 2016-04-10 |
| US20150044221A1 (en) | 2015-02-12 |
| BR112014021099A2 (pt) | 2020-12-01 |
| US9260513B2 (en) | 2016-02-16 |
| AU2013223137B2 (en) | 2017-10-19 |
| JPWO2013125630A1 (ja) | 2015-07-30 |
| IN2014KN01714A (enExample) | 2015-10-23 |
| DK2818481T3 (da) | 2019-10-14 |
| EP2818481A1 (en) | 2014-12-31 |
| WO2013125630A1 (ja) | 2013-08-29 |
| CN104114581B (zh) | 2018-11-30 |
| CN104114581A (zh) | 2014-10-22 |
| MX2014009747A (es) | 2014-11-14 |
| ES2749672T3 (es) | 2020-03-23 |
| HUE046788T2 (hu) | 2020-03-30 |
| EP2818481B1 (en) | 2019-08-07 |
| PL2818481T3 (pl) | 2020-02-28 |
| KR102005308B1 (ko) | 2019-07-30 |
| KR20140130670A (ko) | 2014-11-11 |
| EP2818481A4 (en) | 2015-10-07 |
| CA2864999A1 (en) | 2013-08-29 |
| JP6187257B2 (ja) | 2017-08-30 |
| MX363136B (es) | 2019-03-12 |
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