CA2861479C - Paroxetine derivative - Google Patents
Paroxetine derivative Download PDFInfo
- Publication number
- CA2861479C CA2861479C CA2861479A CA2861479A CA2861479C CA 2861479 C CA2861479 C CA 2861479C CA 2861479 A CA2861479 A CA 2861479A CA 2861479 A CA2861479 A CA 2861479A CA 2861479 C CA2861479 C CA 2861479C
- Authority
- CA
- Canada
- Prior art keywords
- compound
- acceptable salt
- group
- pharmacologically acceptable
- paroxetine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4525—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with oxygen as a ring hetero atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
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Applications Claiming Priority (3)
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| US201261592896P | 2012-01-31 | 2012-01-31 | |
| US61/592896 | 2012-01-31 | ||
| PCT/JP2013/051858 WO2013115163A1 (ja) | 2012-01-31 | 2013-01-29 | パロキセチン誘導体 |
Publications (2)
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| CA2861479A1 CA2861479A1 (en) | 2013-08-08 |
| CA2861479C true CA2861479C (en) | 2017-10-10 |
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| CA2861479A Expired - Fee Related CA2861479C (en) | 2012-01-31 | 2013-01-29 | Paroxetine derivative |
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| AR (1) | AR089837A1 (enExample) |
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| BR (1) | BR112014016197A8 (enExample) |
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| RU (1) | RU2616610C2 (enExample) |
| TW (1) | TW201334783A (enExample) |
| WO (1) | WO2013115163A1 (enExample) |
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| MA43313B1 (fr) * | 2015-09-02 | 2022-06-30 | Trevena Inc | Aza-hétérocyclique à 6 éléments contenant des composés modulateurs de récepteurs opioïdes delta, et leurs procédés de fabrication et d'utilisation |
| CN110446495B (zh) | 2017-02-17 | 2023-09-05 | 特维娜有限公司 | 含有7元氮杂杂环的δ阿片受体调节化合物及其使用和制备方法 |
| CN111533682B (zh) * | 2020-05-29 | 2022-03-01 | 清华大学 | 帕罗西汀及其类似物的制备方法 |
| CN116406268A (zh) | 2020-10-27 | 2023-07-07 | 特维娜有限公司 | δ-阿片样物质调节剂的结晶和无定形形式 |
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| GB1422263A (en) | 1973-01-30 | 1976-01-21 | Ferrosan As | 4-phenyl-piperidine compounds |
| JP2002503248A (ja) | 1997-06-10 | 2002-01-29 | シントン・ベスローテン・フェンノートシャップ | ４−フェニルピペリジン化合物 |
| IT1308629B1 (it) * | 1999-02-23 | 2002-01-09 | Recordati Chem Pharm | Processo per la produzione di paroxetina. |
| CN101273024A (zh) * | 2005-07-29 | 2008-09-24 | 康瑟特制药公司 | 新颖苯并[d][1,3]-二氧杂环戊烯衍生物 |
| US20070142389A1 (en) * | 2005-12-20 | 2007-06-21 | Pfizer Inc. | Piperidine derivatives |
| JP2009184924A (ja) | 2006-05-31 | 2009-08-20 | Eisai R & D Management Co Ltd | 生物学的試薬用化合物 |
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- 2013-01-29 BR BR112014016197A patent/BR112014016197A8/pt active Search and Examination
- 2013-01-29 CN CN201380005183.XA patent/CN104039777B/zh not_active Expired - Fee Related
- 2013-01-29 TW TW102103327A patent/TW201334783A/zh unknown
- 2013-01-29 WO PCT/JP2013/051858 patent/WO2013115163A1/ja not_active Ceased
- 2013-01-29 JP JP2013556400A patent/JP6055784B2/ja not_active Expired - Fee Related
- 2013-01-29 RU RU2014126321A patent/RU2616610C2/ru not_active IP Right Cessation
- 2013-01-29 CA CA2861479A patent/CA2861479C/en not_active Expired - Fee Related
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- 2013-01-29 AU AU2013216123A patent/AU2013216123B2/en not_active Ceased
- 2013-01-29 KR KR1020147021114A patent/KR101950057B1/ko not_active Expired - Fee Related
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Also Published As
| Publication number | Publication date |
|---|---|
| IL233327A (en) | 2016-03-31 |
| KR101950057B1 (ko) | 2019-02-19 |
| IL233327A0 (en) | 2014-08-31 |
| JP6055784B2 (ja) | 2016-12-27 |
| CN104039777B (zh) | 2016-03-02 |
| AR089837A1 (es) | 2014-09-17 |
| EP2810942B1 (en) | 2016-03-30 |
| CA2861479A1 (en) | 2013-08-08 |
| EP2810942A4 (en) | 2015-07-01 |
| CN104039777A (zh) | 2014-09-10 |
| ES2576082T3 (es) | 2016-07-05 |
| TW201334783A (zh) | 2013-09-01 |
| RU2014126321A (ru) | 2016-03-20 |
| AU2013216123B2 (en) | 2016-10-20 |
| RU2616610C2 (ru) | 2017-04-18 |
| US8933100B2 (en) | 2015-01-13 |
| EP2810942A1 (en) | 2014-12-10 |
| US20130197033A1 (en) | 2013-08-01 |
| MX355654B (es) | 2018-04-26 |
| JPWO2013115163A1 (ja) | 2015-05-11 |
| KR20140117454A (ko) | 2014-10-07 |
| IN2014CN04922A (enExample) | 2015-09-18 |
| MX2014007620A (es) | 2014-09-15 |
| WO2013115163A1 (ja) | 2013-08-08 |
| BR112014016197A8 (pt) | 2017-07-04 |
| AU2013216123A1 (en) | 2014-07-17 |
| BR112014016197A2 (pt) | 2017-06-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request |
Effective date: 20160210 |
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| MKLA | Lapsed |
Effective date: 20210129 |