MX355654B - Derivado de paroxetina. - Google Patents
Derivado de paroxetina.Info
- Publication number
- MX355654B MX355654B MX2014007620A MX2014007620A MX355654B MX 355654 B MX355654 B MX 355654B MX 2014007620 A MX2014007620 A MX 2014007620A MX 2014007620 A MX2014007620 A MX 2014007620A MX 355654 B MX355654 B MX 355654B
- Authority
- MX
- Mexico
- Prior art keywords
- paroxetine
- formula
- derivative
- paroxetine derivative
- retains
- Prior art date
Links
- AHOUBRCZNHFOSL-YOEHRIQHSA-N (+)-Casbol Chemical class C1=CC(F)=CC=C1[C@H]1[C@H](COC=2C=C3OCOC3=CC=2)CNCC1 AHOUBRCZNHFOSL-YOEHRIQHSA-N 0.000 title abstract 2
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 1
- AHOUBRCZNHFOSL-UHFFFAOYSA-N Paroxetine hydrochloride Natural products C1=CC(F)=CC=C1C1C(COC=2C=C3OCOC3=CC=2)CNCC1 AHOUBRCZNHFOSL-UHFFFAOYSA-N 0.000 abstract 1
- 230000009286 beneficial effect Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 229960002296 paroxetine Drugs 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4525—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with oxygen as a ring hetero atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261592896P | 2012-01-31 | 2012-01-31 | |
| PCT/JP2013/051858 WO2013115163A1 (ja) | 2012-01-31 | 2013-01-29 | パロキセチン誘導体 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2014007620A MX2014007620A (es) | 2014-09-15 |
| MX355654B true MX355654B (es) | 2018-04-26 |
Family
ID=48870749
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2014007620A MX355654B (es) | 2012-01-31 | 2013-01-29 | Derivado de paroxetina. |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US8933100B2 (enExample) |
| EP (1) | EP2810942B1 (enExample) |
| JP (1) | JP6055784B2 (enExample) |
| KR (1) | KR101950057B1 (enExample) |
| CN (1) | CN104039777B (enExample) |
| AR (1) | AR089837A1 (enExample) |
| AU (1) | AU2013216123B2 (enExample) |
| BR (1) | BR112014016197A8 (enExample) |
| CA (1) | CA2861479C (enExample) |
| ES (1) | ES2576082T3 (enExample) |
| IL (1) | IL233327A (enExample) |
| IN (1) | IN2014CN04922A (enExample) |
| MX (1) | MX355654B (enExample) |
| RU (1) | RU2616610C2 (enExample) |
| TW (1) | TW201334783A (enExample) |
| WO (1) | WO2013115163A1 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MA43313B1 (fr) * | 2015-09-02 | 2022-06-30 | Trevena Inc | Aza-hétérocyclique à 6 éléments contenant des composés modulateurs de récepteurs opioïdes delta, et leurs procédés de fabrication et d'utilisation |
| CN110446495B (zh) | 2017-02-17 | 2023-09-05 | 特维娜有限公司 | 含有7元氮杂杂环的δ阿片受体调节化合物及其使用和制备方法 |
| CN111533682B (zh) * | 2020-05-29 | 2022-03-01 | 清华大学 | 帕罗西汀及其类似物的制备方法 |
| CN116406268A (zh) | 2020-10-27 | 2023-07-07 | 特维娜有限公司 | δ-阿片样物质调节剂的结晶和无定形形式 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1422263A (en) | 1973-01-30 | 1976-01-21 | Ferrosan As | 4-phenyl-piperidine compounds |
| JP2002503248A (ja) | 1997-06-10 | 2002-01-29 | シントン・ベスローテン・フェンノートシャップ | ４−フェニルピペリジン化合物 |
| IT1308629B1 (it) * | 1999-02-23 | 2002-01-09 | Recordati Chem Pharm | Processo per la produzione di paroxetina. |
| CN101273024A (zh) * | 2005-07-29 | 2008-09-24 | 康瑟特制药公司 | 新颖苯并[d][1,3]-二氧杂环戊烯衍生物 |
| US20070142389A1 (en) * | 2005-12-20 | 2007-06-21 | Pfizer Inc. | Piperidine derivatives |
| JP2009184924A (ja) | 2006-05-31 | 2009-08-20 | Eisai R & D Management Co Ltd | 生物学的試薬用化合物 |
-
2013
- 2013-01-29 EP EP13744409.7A patent/EP2810942B1/en not_active Not-in-force
- 2013-01-29 BR BR112014016197A patent/BR112014016197A8/pt active Search and Examination
- 2013-01-29 CN CN201380005183.XA patent/CN104039777B/zh not_active Expired - Fee Related
- 2013-01-29 TW TW102103327A patent/TW201334783A/zh unknown
- 2013-01-29 WO PCT/JP2013/051858 patent/WO2013115163A1/ja not_active Ceased
- 2013-01-29 JP JP2013556400A patent/JP6055784B2/ja not_active Expired - Fee Related
- 2013-01-29 RU RU2014126321A patent/RU2616610C2/ru not_active IP Right Cessation
- 2013-01-29 CA CA2861479A patent/CA2861479C/en not_active Expired - Fee Related
- 2013-01-29 IN IN4922CHN2014 patent/IN2014CN04922A/en unknown
- 2013-01-29 AU AU2013216123A patent/AU2013216123B2/en not_active Ceased
- 2013-01-29 KR KR1020147021114A patent/KR101950057B1/ko not_active Expired - Fee Related
- 2013-01-29 ES ES13744409.7T patent/ES2576082T3/es active Active
- 2013-01-29 MX MX2014007620A patent/MX355654B/es active IP Right Grant
- 2013-01-29 AR ARP130100262A patent/AR089837A1/es unknown
- 2013-01-29 US US13/752,638 patent/US8933100B2/en not_active Expired - Fee Related
-
2014
- 2014-06-23 IL IL233327A patent/IL233327A/en active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| IL233327A (en) | 2016-03-31 |
| KR101950057B1 (ko) | 2019-02-19 |
| CA2861479C (en) | 2017-10-10 |
| IL233327A0 (en) | 2014-08-31 |
| JP6055784B2 (ja) | 2016-12-27 |
| CN104039777B (zh) | 2016-03-02 |
| AR089837A1 (es) | 2014-09-17 |
| EP2810942B1 (en) | 2016-03-30 |
| CA2861479A1 (en) | 2013-08-08 |
| EP2810942A4 (en) | 2015-07-01 |
| CN104039777A (zh) | 2014-09-10 |
| ES2576082T3 (es) | 2016-07-05 |
| TW201334783A (zh) | 2013-09-01 |
| RU2014126321A (ru) | 2016-03-20 |
| AU2013216123B2 (en) | 2016-10-20 |
| RU2616610C2 (ru) | 2017-04-18 |
| US8933100B2 (en) | 2015-01-13 |
| EP2810942A1 (en) | 2014-12-10 |
| US20130197033A1 (en) | 2013-08-01 |
| JPWO2013115163A1 (ja) | 2015-05-11 |
| KR20140117454A (ko) | 2014-10-07 |
| IN2014CN04922A (enExample) | 2015-09-18 |
| MX2014007620A (es) | 2014-09-15 |
| WO2013115163A1 (ja) | 2013-08-08 |
| BR112014016197A8 (pt) | 2017-07-04 |
| AU2013216123A1 (en) | 2014-07-17 |
| BR112014016197A2 (pt) | 2017-06-13 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CA2875877C (en) | Syk inhibitors | |
| IN2014MN01897A (enExample) | ||
| MD20180040A2 (ro) | Inhibitori ai virusului hepatic C | |
| PH12017501429A1 (en) | Derivatives of betulin | |
| MX365776B (es) | Derivado de sulfuro de alquil fenilo y agente de control de plagas. | |
| PH12015500209A1 (en) | Partially saturated nitrogen-containing heterocyclic compound | |
| GEP201606532B (en) | Benzamide derivatives for inhibiting the activity of abl1, abl2 and bcr-abl1 | |
| MX2021008356A (es) | Inhibidores de jak2 y alk2 y metodos para su uso. | |
| PH12016501079A1 (en) | (6S,9aS)-N-BENZYL-6-[(4-HYDROXYPHENYL)METHYL]-4,7-DIOXO-8-({6-[3-(PIPERAZINE-1-YL)AZETIDINE-1-YL]PYRIDINE-2-YL}METHYL)-2-(PROP-2-EN-1-YL)-OCTAHYDRO-1H-PYRAZINO[2,1-c][1,2,4]TRIAZINE-1-CARBOXAMIDE COMPOUND | |
| AU2012313888A8 (en) | 3-pyrimidin-4-yl-oxazolidin-2-ones as inhibitors of mutant IDH | |
| PH12014500883A1 (en) | Uracil derivatives as axl and c-met kinase inhibitors | |
| MX2013011589A (es) | Metodos y composiciones para tratar enfermedad de parkinson. | |
| PH12015501813A1 (en) | Monocyclic pyridine derivative | |
| IN2014DN07509A (enExample) | ||
| IN2012DN00765A (enExample) | ||
| WO2014197345A3 (en) | Imidazole derivatives and methods of use thereof for improving the pharmacokinetics of a drug | |
| IN2014CN04449A (enExample) | ||
| MY170262A (en) | Dicarboxylic acid compound | |
| MX2016004963A (es) | Sal y formas cristalinas de inhibidores de quinasa tipo polo-4. | |
| PH12013501840A1 (en) | Nitrogen-containing saturated heterocyclic compound | |
| MY185971A (en) | Pyranodipyridine compound | |
| PH12015501146A1 (en) | Hydantoin derivative | |
| MX359399B (es) | Inhibidores de 17alfa-hidroxilasa/c17-20-liasa. | |
| IN2014CN04922A (enExample) | ||
| MY162945A (en) | Azole derivative |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration |