IN2014CN04922A - - Google Patents
Info
- Publication number
- IN2014CN04922A IN2014CN04922A IN4922CHN2014A IN2014CN04922A IN 2014CN04922 A IN2014CN04922 A IN 2014CN04922A IN 4922CHN2014 A IN4922CHN2014 A IN 4922CHN2014A IN 2014CN04922 A IN2014CN04922 A IN 2014CN04922A
- Authority
- IN
- India
- Prior art keywords
- formula
- paroxetine
- retains
- pharmaceutically acceptable
- alkyl group
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4525—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with oxygen as a ring hetero atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
11 6A compound represented by formula (1) or a pharmaceutically acceptable salt thereof retains the main beneficial effects of paroxetine while having an improved CYP inhibitory action. (1) [In the formula R is a hydrogen atom or a C alkyl group.]
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261592896P | 2012-01-31 | 2012-01-31 | |
PCT/JP2013/051858 WO2013115163A1 (en) | 2012-01-31 | 2013-01-29 | Paroxetine derivative |
Publications (1)
Publication Number | Publication Date |
---|---|
IN2014CN04922A true IN2014CN04922A (en) | 2015-09-18 |
Family
ID=48870749
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IN4922CHN2014 IN2014CN04922A (en) | 2012-01-31 | 2013-01-29 |
Country Status (16)
Country | Link |
---|---|
US (1) | US8933100B2 (en) |
EP (1) | EP2810942B1 (en) |
JP (1) | JP6055784B2 (en) |
KR (1) | KR101950057B1 (en) |
CN (1) | CN104039777B (en) |
AR (1) | AR089837A1 (en) |
AU (1) | AU2013216123B2 (en) |
BR (1) | BR112014016197A8 (en) |
CA (1) | CA2861479C (en) |
ES (1) | ES2576082T3 (en) |
IL (1) | IL233327A (en) |
IN (1) | IN2014CN04922A (en) |
MX (1) | MX355654B (en) |
RU (1) | RU2616610C2 (en) |
TW (1) | TW201334783A (en) |
WO (1) | WO2013115163A1 (en) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SI3344248T1 (en) * | 2015-09-02 | 2022-07-29 | Trevena, Inc. | 6-membered aza-heterocyclic containing delta-opioid receptor modulating compounds, methods of using and making the same |
JP7185633B2 (en) | 2017-02-17 | 2022-12-07 | トレベナ・インコーポレイテッド | Delta-Opioid Receptor Modulating Compounds Containing 7-Membered Azaheterocycles, Methods of Use and Preparation Thereof |
CN111533682B (en) * | 2020-05-29 | 2022-03-01 | 清华大学 | Process for preparing paroxetine and analogues thereof |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1422263A (en) | 1973-01-30 | 1976-01-21 | Ferrosan As | 4-phenyl-piperidine compounds |
ES2155995T3 (en) * | 1997-06-10 | 2001-06-01 | Synthon Bv | 4-PHENYLPIPERIDINE COMPOUNDS. |
IT1308629B1 (en) * | 1999-02-23 | 2002-01-09 | Recordati Chem Pharm | PROCESS FOR THE PRODUCTION OF PAROXETIN. |
JP5301991B2 (en) | 2005-07-29 | 2013-09-25 | コンサート ファーマシューティカルズ インコーポレイテッド | Novel benzo [d] [1,3] -dioxole derivatives |
US20070142389A1 (en) * | 2005-12-20 | 2007-06-21 | Pfizer Inc. | Piperidine derivatives |
JP2009184924A (en) | 2006-05-31 | 2009-08-20 | Eisai R & D Management Co Ltd | Compound for biological reagent |
-
2013
- 2013-01-29 TW TW102103327A patent/TW201334783A/en unknown
- 2013-01-29 BR BR112014016197A patent/BR112014016197A8/en active Search and Examination
- 2013-01-29 RU RU2014126321A patent/RU2616610C2/en not_active IP Right Cessation
- 2013-01-29 WO PCT/JP2013/051858 patent/WO2013115163A1/en active Application Filing
- 2013-01-29 EP EP13744409.7A patent/EP2810942B1/en not_active Not-in-force
- 2013-01-29 MX MX2014007620A patent/MX355654B/en active IP Right Grant
- 2013-01-29 AU AU2013216123A patent/AU2013216123B2/en not_active Ceased
- 2013-01-29 AR ARP130100262A patent/AR089837A1/en unknown
- 2013-01-29 KR KR1020147021114A patent/KR101950057B1/en active IP Right Grant
- 2013-01-29 CA CA2861479A patent/CA2861479C/en not_active Expired - Fee Related
- 2013-01-29 US US13/752,638 patent/US8933100B2/en not_active Expired - Fee Related
- 2013-01-29 JP JP2013556400A patent/JP6055784B2/en not_active Expired - Fee Related
- 2013-01-29 CN CN201380005183.XA patent/CN104039777B/en not_active Expired - Fee Related
- 2013-01-29 IN IN4922CHN2014 patent/IN2014CN04922A/en unknown
- 2013-01-29 ES ES13744409.7T patent/ES2576082T3/en active Active
-
2014
- 2014-06-23 IL IL233327A patent/IL233327A/en active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
EP2810942A1 (en) | 2014-12-10 |
CA2861479C (en) | 2017-10-10 |
AU2013216123A1 (en) | 2014-07-17 |
TW201334783A (en) | 2013-09-01 |
WO2013115163A1 (en) | 2013-08-08 |
RU2616610C2 (en) | 2017-04-18 |
US20130197033A1 (en) | 2013-08-01 |
US8933100B2 (en) | 2015-01-13 |
IL233327A0 (en) | 2014-08-31 |
BR112014016197A8 (en) | 2017-07-04 |
CA2861479A1 (en) | 2013-08-08 |
JP6055784B2 (en) | 2016-12-27 |
MX355654B (en) | 2018-04-26 |
KR20140117454A (en) | 2014-10-07 |
CN104039777A (en) | 2014-09-10 |
CN104039777B (en) | 2016-03-02 |
EP2810942A4 (en) | 2015-07-01 |
JPWO2013115163A1 (en) | 2015-05-11 |
MX2014007620A (en) | 2014-09-15 |
RU2014126321A (en) | 2016-03-20 |
KR101950057B1 (en) | 2019-02-19 |
EP2810942B1 (en) | 2016-03-30 |
AR089837A1 (en) | 2014-09-17 |
IL233327A (en) | 2016-03-31 |
BR112014016197A2 (en) | 2017-06-13 |
ES2576082T3 (en) | 2016-07-05 |
AU2013216123B2 (en) | 2016-10-20 |
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IN2014CN04922A (en) |