CA2853484C - Cysteamine in the treatment of fibrotic disease - Google Patents
Cysteamine in the treatment of fibrotic disease Download PDFInfo
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- CA2853484C CA2853484C CA2853484A CA2853484A CA2853484C CA 2853484 C CA2853484 C CA 2853484C CA 2853484 A CA2853484 A CA 2853484A CA 2853484 A CA2853484 A CA 2853484A CA 2853484 C CA2853484 C CA 2853484C
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- cysteamine
- fibrosis
- interstitial
- salt
- patient
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
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- Biomedical Technology (AREA)
- Physical Education & Sports Medicine (AREA)
- Urology & Nephrology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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| JP7418958B2 (ja) * | 2016-03-17 | 2024-01-22 | チオジェネシス セラピューティクス， インコーポレイテッド | システアミンの制御放出のための組成物及びシステアミン感受性障害の全身治療 |
| US10155948B2 (en) * | 2016-05-12 | 2018-12-18 | Kangwon National University University-Industry Cooperation Foundation and | Pharmaceutical composition for preventing or treating diabetic complications and screening method for preventive or therapeutic agent for diabetic complications |
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| WO2020210218A1 (en) * | 2019-04-12 | 2020-10-15 | The Regents Of The University Of California | Methods for treating inherited eye defects |
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| US5571714A (en) | 1988-12-22 | 1996-11-05 | Celtrix Pharmaceuticals, Inc. | Monoclonal antibodies which bind both transforming growth factors β1 and β2 and methods of use |
| ATE154514T1 (de) | 1989-09-29 | 1997-07-15 | Jolla Cancer Res Found | Inhibierung des transformierenden wachstumsfaktor zur verhinderung der anhäufung extrazellulärer matrix |
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| AU671606B2 (en) | 1991-10-31 | 1996-09-05 | Whitehead Institute For Biomedical Research | TGF-beta type receptor cDNAs and uses therefor |
| US6008011A (en) | 1991-10-31 | 1999-12-28 | Whitehead Institute For Biomedical Research | TGF-β type II receptor cDNAs |
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| GB9205800D0 (en) | 1992-03-17 | 1992-04-29 | British Tech Group | Treatment of fibrotic disorders |
| US5869462A (en) | 1992-09-10 | 1999-02-09 | The Board Of Trustees Of The Leland Stanford Junior University | Inhibition of proliferation of vascular smooth muscle cell |
| US5821234A (en) | 1992-09-10 | 1998-10-13 | The Board Of Trustees Of The Leland Stanford Junior University | Inhibition of proliferation of vascular smooth muscle cell |
| AU5587094A (en) | 1992-10-26 | 1994-05-24 | Kirin Brewery Company, Limited | Method for producing large latent transforming growth factor-beta complexes and large latency associated peptide |
| DE69332026T2 (de) | 1992-10-29 | 2002-10-31 | Celtrix Pharmaceuticals, Inc. | Typ ii tgf-beta-bindendes rezeptorfragment als therapeutisches mittel |
| US5830847A (en) | 1992-10-30 | 1998-11-03 | Hsc Research & Development Limited Partnership | Soluble TGF-β-binding endoglin polypeptides and homodimers |
| AU5541094A (en) | 1992-10-30 | 1994-05-24 | Consejo Superior De Investigaciones Cientificas | Compositions and methods for modifying the regulatory activity of tgf-beta |
| ATE211762T1 (de) | 1993-04-30 | 2002-01-15 | Biognostik Ges | Antisense-oligonukleotide zur behandlung des immunsuppressiven effektes des transformierenden wachstumsfaktor-beta1(tgf-beta1) |
| WO1995000103A2 (en) | 1993-06-15 | 1995-01-05 | Il-Yang Pharm. Co., Ltd. | Anti-sense oligodeoxynucleotide to fibrogenic cytokines and use thereof |
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| JPH09512910A (ja) | 1994-05-04 | 1997-12-22 | マウント・サイナイ・ホスピタル・コーポレイション | ＴＧＦ−βスーパーファミリーのサイトカインの変調因子およびそのアッセイ方法 |
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| IN2014DN03049A (OSRAM) | 2015-05-15 |
| US9925154B2 (en) | 2018-03-27 |
| CA2853484A1 (en) | 2013-05-02 |
| WO2013062544A1 (en) | 2013-05-02 |
| US20140275279A1 (en) | 2014-09-18 |
| AU2011379972A1 (en) | 2014-05-15 |
| US9468612B2 (en) | 2016-10-18 |
| US20170165207A1 (en) | 2017-06-15 |
| MX2014004994A (es) | 2014-08-27 |
| AU2011379972B2 (en) | 2016-05-12 |
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