CA2837341C - Method of determining vasoreactivity using inhaled nitric oxide - Google Patents

Method of determining vasoreactivity using inhaled nitric oxide Download PDF

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Publication number
CA2837341C
CA2837341C CA2837341A CA2837341A CA2837341C CA 2837341 C CA2837341 C CA 2837341C CA 2837341 A CA2837341 A CA 2837341A CA 2837341 A CA2837341 A CA 2837341A CA 2837341 C CA2837341 C CA 2837341C
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CA
Canada
Prior art keywords
patient
vasoreactivity
determining
nitric oxide
inhaled nitric
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA2837341A
Other languages
English (en)
French (fr)
Other versions
CA2837341A1 (en
Inventor
Tammy WATTS
Robert F. Roscigno
David H. Fine
Lewis J. Rubin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Vero Biotech Inc
Original Assignee
Vero Biotech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vero Biotech Inc filed Critical Vero Biotech Inc
Publication of CA2837341A1 publication Critical patent/CA2837341A1/en
Application granted granted Critical
Publication of CA2837341C publication Critical patent/CA2837341C/en
Active legal-status Critical Current
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
    • A61B5/026—Measuring blood flow
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/10—Preparation of respiratory gases or vapours
    • A61M16/12—Preparation of respiratory gases or vapours by mixing different gases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Pulmonology (AREA)
  • Physiology (AREA)
  • Medical Informatics (AREA)
  • Emergency Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Anesthesiology (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Steroid Compounds (AREA)
CA2837341A 2011-05-27 2012-05-24 Method of determining vasoreactivity using inhaled nitric oxide Active CA2837341C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161490929P 2011-05-27 2011-05-27
US61/490,929 2011-05-27
PCT/US2012/039401 WO2012166534A1 (en) 2011-05-27 2012-05-24 Method of determining vasoreactivity using inhaled nitric oxide

Publications (2)

Publication Number Publication Date
CA2837341A1 CA2837341A1 (en) 2012-12-06
CA2837341C true CA2837341C (en) 2021-10-19

Family

ID=47259769

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2837341A Active CA2837341C (en) 2011-05-27 2012-05-24 Method of determining vasoreactivity using inhaled nitric oxide

Country Status (6)

Country Link
US (1) US11154210B2 (https=)
EP (1) EP2713723B1 (https=)
JP (3) JP2014527025A (https=)
AU (1) AU2012262534B2 (https=)
CA (1) CA2837341C (https=)
WO (1) WO2012166534A1 (https=)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7618594B2 (en) 2004-08-18 2009-11-17 Geno Llc Conversion of nitrogen dioxide (NO2) to nitric oxide (NO)
AU2005277397B2 (en) 2004-08-18 2011-08-25 VERO Biotech LLC. Conversion of nitrogen dioxide (NO2) to nitric oxide (NO)
US7914743B2 (en) 2008-01-28 2011-03-29 Geno Llc Conversion of nitrogen dioxide (NO2) to nitric oxide (NO)
US8607785B2 (en) 2008-08-21 2013-12-17 Geno Llc Systems and devices for generating nitric oxide
JP5878866B2 (ja) 2009-06-22 2016-03-08 ゲノ エルエルシー 一酸化窒素治療
JP2014527025A (ja) 2011-05-27 2014-10-09 ゲノ エルエルシー 吸入用一酸化窒素を用いて血管反応性を決定する方法
EP4024719A1 (en) 2014-04-15 2022-07-06 CommScope Technologies LLC Wideband remote unit for distributed antenna system
EP3413899A4 (en) * 2016-02-12 2019-10-02 Mallinckrodt Hospital Products IP Limited USE AND MONITORING OF INHALED STAIN OXIDE WITH LEFT-VENTRICULAR SUPPORT DEVICES
MX2020010523A (es) 2017-02-27 2021-02-09 Third Pole Inc Sistemas y metodos para generar oxido nitrico.
RU2717525C1 (ru) 2017-02-27 2020-03-23 Сёрд Поул, Инк. Системы и способы получения оксида азота
US10328228B2 (en) 2017-02-27 2019-06-25 Third Pole, Inc. Systems and methods for ambulatory generation of nitric oxide
US11672938B1 (en) 2018-07-18 2023-06-13 Vero Biotech LLC Start-up protocols for nitric oxide delivery device
US20210386944A1 (en) * 2018-10-12 2021-12-16 Sanotize Research Development Corp. Gas-evolving compositions and container and delivery systems
EP3969416A4 (en) 2019-05-15 2023-11-01 Third Pole, Inc. SYSTEMS AND DEVICES FOR GENERATING NITROGEN OXIDE
JP2022533628A (ja) 2019-05-15 2022-07-25 サード ポール，インコーポレイテッド 一酸化窒素生成用電極
EP3969016A4 (en) 2019-05-15 2023-08-16 Third Pole, Inc. ARCHITECTURES FOR THE PRODUCTION OF NITROUS OXIDE
US11691879B2 (en) 2020-01-11 2023-07-04 Third Pole, Inc. Systems and methods for nitric oxide generation with humidity control
US20210395905A1 (en) 2020-06-18 2021-12-23 Third Pole, Inc. Systems and methods for preventing and treating infections with nitric oxide
WO2022082072A1 (en) 2020-10-16 2022-04-21 Third Pole, Inc. Nitric oxide generation process controls
US11975139B2 (en) 2021-09-23 2024-05-07 Third Pole, Inc. Systems and methods for delivering nitric oxide
US12569628B2 (en) 2022-04-14 2026-03-10 Third Pole, Inc. Delivery of medicinal gas in a liquid medium

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6758214B2 (en) 2000-01-28 2004-07-06 Cyterra Corporation Simple nitric oxide generator for ambulatory and/or bedside inhaled no treatment
US7040313B2 (en) 2001-09-05 2006-05-09 Cyterra Corporation Method and apparatus for nitric oxide generation
AU2005277397B2 (en) 2004-08-18 2011-08-25 VERO Biotech LLC. Conversion of nitrogen dioxide (NO2) to nitric oxide (NO)
US7618594B2 (en) 2004-08-18 2009-11-17 Geno Llc Conversion of nitrogen dioxide (NO2) to nitric oxide (NO)
CA2588994A1 (en) 2004-12-08 2006-06-15 Biomarin Pharmaceutical Inc. Methods and compositions for the treatment of pulmonary hypertension of the newborn
WO2007087575A2 (en) * 2006-01-24 2007-08-02 University Of Chicago Compositions and methods for treating pulmonary hypertension
AU2008232413B2 (en) 2007-03-23 2013-09-19 VERO Biotech LLC. Conversion of nitrogen dioxide (NO2) to nitric oxide (NO)
US7914743B2 (en) 2008-01-28 2011-03-29 Geno Llc Conversion of nitrogen dioxide (NO2) to nitric oxide (NO)
EP2306814B1 (en) 2008-07-24 2013-11-27 Geno LLC Methods for diagnosing and treating a heart condition in a patient
US8607785B2 (en) 2008-08-21 2013-12-17 Geno Llc Systems and devices for generating nitric oxide
US10780241B2 (en) 2008-08-21 2020-09-22 Vero Biotech LLC Devices and methods for minimizing and treating high-altitude sickness
US8701657B2 (en) 2008-08-21 2014-04-22 Geno Llc Systems for generating nitric oxide
US10960168B2 (en) 2008-08-21 2021-03-30 Vero Biotech LLC Delivery of high concentration nitric oxide
EP2362810A4 (en) 2008-09-22 2013-09-11 Geno Llc CONVERSION OF NITROGEN DIOXIDE (NO2) TO NITROGEN MONOXIDE (NO)
JP5878866B2 (ja) 2009-06-22 2016-03-08 ゲノ エルエルシー 一酸化窒素治療
CA2671029A1 (en) * 2009-06-30 2010-12-30 James S. Baldassarre Methods of treating term and near-term neonates having hypoxic respiratory failure associated with clinical or echocardiographic evidence of pulmonary hypertension
WO2011063335A1 (en) * 2009-11-20 2011-05-26 Geno Llc Nitric oxide delivery system
US20120093948A1 (en) * 2009-11-20 2012-04-19 Fine David H Nitric Oxide Treatments
EP2563435B1 (en) 2010-04-26 2020-06-03 VERO Biotech LLC Delivery of ultra pure nitric oxide (no)
US8268252B2 (en) 2010-04-26 2012-09-18 Geno Llc Nitrosyl special connector
USD688352S1 (en) 2010-04-27 2013-08-20 Geno Llc Female gas connector
USD679366S1 (en) 2010-04-27 2013-04-02 Geno Llc Male gas connector
AU2011336358B2 (en) * 2010-12-03 2016-09-29 VERO Biotech LLC. Nitric oxide treatments
US20140051737A1 (en) * 2011-05-10 2014-02-20 Universite Laval Methods for the treatment and diagnostic of pulmonary arterial hypertension
JP2014527025A (ja) 2011-05-27 2014-10-09 ゲノ エルエルシー 吸入用一酸化窒素を用いて血管反応性を決定する方法
CA3211190A1 (en) 2014-10-20 2016-04-28 Vero Biotech LLC Nitrogen dioxide storage cassette

Also Published As

Publication number Publication date
JP2017165731A (ja) 2017-09-21
AU2012262534A1 (en) 2013-12-12
JP2019131556A (ja) 2019-08-08
EP2713723A4 (en) 2015-03-25
EP2713723A1 (en) 2014-04-09
AU2012262534B2 (en) 2016-06-02
EP2713723B1 (en) 2018-09-12
JP2014527025A (ja) 2014-10-09
CA2837341A1 (en) 2012-12-06
WO2012166534A1 (en) 2012-12-06
US20130309328A1 (en) 2013-11-21
US11154210B2 (en) 2021-10-26

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