AU2012262534B2 - Method of determining vasoreactivity using inhaled nitric oxide - Google Patents

Method of determining vasoreactivity using inhaled nitric oxide Download PDF

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Publication number
AU2012262534B2
AU2012262534B2 AU2012262534A AU2012262534A AU2012262534B2 AU 2012262534 B2 AU2012262534 B2 AU 2012262534B2 AU 2012262534 A AU2012262534 A AU 2012262534A AU 2012262534 A AU2012262534 A AU 2012262534A AU 2012262534 B2 AU2012262534 B2 AU 2012262534B2
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AU
Australia
Prior art keywords
patient
vasoactive agent
hemodynamics
indicator
pulmonary
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2012262534A
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English (en)
Other versions
AU2012262534A1 (en
Inventor
David H. Fine
Robert F. Roscigno
Lewis J. Rubin
Tammy WATTS
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Vero Biotech Inc
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Vero Biotech Inc
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Publication date
Application filed by Vero Biotech Inc filed Critical Vero Biotech Inc
Publication of AU2012262534A1 publication Critical patent/AU2012262534A1/en
Application granted granted Critical
Publication of AU2012262534B2 publication Critical patent/AU2012262534B2/en
Assigned to VERO Biotech LLC. reassignment VERO Biotech LLC. Request to Amend Deed and Register Assignors: GENO LLC
Ceased legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/02Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
    • A61B5/026Measuring blood flow
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/10Preparation of respiratory gases or vapours
    • A61M16/12Preparation of respiratory gases or vapours by mixing different gases
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Pulmonology (AREA)
  • Physiology (AREA)
  • Medical Informatics (AREA)
  • Emergency Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Anesthesiology (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Steroid Compounds (AREA)
AU2012262534A 2011-05-27 2012-05-24 Method of determining vasoreactivity using inhaled nitric oxide Ceased AU2012262534B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161490929P 2011-05-27 2011-05-27
US61/490,929 2011-05-27
PCT/US2012/039401 WO2012166534A1 (en) 2011-05-27 2012-05-24 Method of determining vasoreactivity using inhaled nitric oxide

Publications (2)

Publication Number Publication Date
AU2012262534A1 AU2012262534A1 (en) 2013-12-12
AU2012262534B2 true AU2012262534B2 (en) 2016-06-02

Family

ID=47259769

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2012262534A Ceased AU2012262534B2 (en) 2011-05-27 2012-05-24 Method of determining vasoreactivity using inhaled nitric oxide

Country Status (6)

Country Link
US (1) US11154210B2 (https=)
EP (1) EP2713723B1 (https=)
JP (3) JP2014527025A (https=)
AU (1) AU2012262534B2 (https=)
CA (1) CA2837341C (https=)
WO (1) WO2012166534A1 (https=)

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US7618594B2 (en) 2004-08-18 2009-11-17 Geno Llc Conversion of nitrogen dioxide (NO2) to nitric oxide (NO)
AU2005277397B2 (en) 2004-08-18 2011-08-25 VERO Biotech LLC. Conversion of nitrogen dioxide (NO2) to nitric oxide (NO)
US7914743B2 (en) 2008-01-28 2011-03-29 Geno Llc Conversion of nitrogen dioxide (NO2) to nitric oxide (NO)
US8607785B2 (en) 2008-08-21 2013-12-17 Geno Llc Systems and devices for generating nitric oxide
JP5878866B2 (ja) 2009-06-22 2016-03-08 ゲノ エルエルシー 一酸化窒素治療
JP2014527025A (ja) 2011-05-27 2014-10-09 ゲノ エルエルシー 吸入用一酸化窒素を用いて血管反応性を決定する方法
EP4024719A1 (en) 2014-04-15 2022-07-06 CommScope Technologies LLC Wideband remote unit for distributed antenna system
EP3413899A4 (en) * 2016-02-12 2019-10-02 Mallinckrodt Hospital Products IP Limited USE AND MONITORING OF INHALED STAIN OXIDE WITH LEFT-VENTRICULAR SUPPORT DEVICES
MX2020010523A (es) 2017-02-27 2021-02-09 Third Pole Inc Sistemas y metodos para generar oxido nitrico.
RU2717525C1 (ru) 2017-02-27 2020-03-23 Сёрд Поул, Инк. Системы и способы получения оксида азота
US10328228B2 (en) 2017-02-27 2019-06-25 Third Pole, Inc. Systems and methods for ambulatory generation of nitric oxide
US11672938B1 (en) 2018-07-18 2023-06-13 Vero Biotech LLC Start-up protocols for nitric oxide delivery device
US20210386944A1 (en) * 2018-10-12 2021-12-16 Sanotize Research Development Corp. Gas-evolving compositions and container and delivery systems
EP3969416A4 (en) 2019-05-15 2023-11-01 Third Pole, Inc. SYSTEMS AND DEVICES FOR GENERATING NITROGEN OXIDE
JP2022533628A (ja) 2019-05-15 2022-07-25 サード ポール,インコーポレイテッド 一酸化窒素生成用電極
EP3969016A4 (en) 2019-05-15 2023-08-16 Third Pole, Inc. ARCHITECTURES FOR THE PRODUCTION OF NITROUS OXIDE
US11691879B2 (en) 2020-01-11 2023-07-04 Third Pole, Inc. Systems and methods for nitric oxide generation with humidity control
US20210395905A1 (en) 2020-06-18 2021-12-23 Third Pole, Inc. Systems and methods for preventing and treating infections with nitric oxide
WO2022082072A1 (en) 2020-10-16 2022-04-21 Third Pole, Inc. Nitric oxide generation process controls
US11975139B2 (en) 2021-09-23 2024-05-07 Third Pole, Inc. Systems and methods for delivering nitric oxide
US12569628B2 (en) 2022-04-14 2026-03-10 Third Pole, Inc. Delivery of medicinal gas in a liquid medium

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006063215A2 (en) * 2004-12-08 2006-06-15 Biomarin Pharmaceutical Inc. Methods and compositions for the treatment of pulmonary hypertension of the newborn
WO2011002606A1 (en) * 2009-06-30 2011-01-06 Ikaria Holdings, Inc. Methods of identifying a patient population eligible for treatment with nitric oxide via inhalation
WO2012075420A1 (en) * 2010-12-03 2012-06-07 Geno Llc Nitric oxide treatments
WO2012151701A1 (en) * 2011-05-10 2012-11-15 Université Laval / Vice-Rectorat À La Recherche Et À La Création Methods for the treatment and diagnostic of pulmonary arterial hypertension

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6758214B2 (en) 2000-01-28 2004-07-06 Cyterra Corporation Simple nitric oxide generator for ambulatory and/or bedside inhaled no treatment
US7040313B2 (en) 2001-09-05 2006-05-09 Cyterra Corporation Method and apparatus for nitric oxide generation
AU2005277397B2 (en) 2004-08-18 2011-08-25 VERO Biotech LLC. Conversion of nitrogen dioxide (NO2) to nitric oxide (NO)
US7618594B2 (en) 2004-08-18 2009-11-17 Geno Llc Conversion of nitrogen dioxide (NO2) to nitric oxide (NO)
WO2007087575A2 (en) * 2006-01-24 2007-08-02 University Of Chicago Compositions and methods for treating pulmonary hypertension
AU2008232413B2 (en) 2007-03-23 2013-09-19 VERO Biotech LLC. Conversion of nitrogen dioxide (NO2) to nitric oxide (NO)
US7914743B2 (en) 2008-01-28 2011-03-29 Geno Llc Conversion of nitrogen dioxide (NO2) to nitric oxide (NO)
EP2306814B1 (en) 2008-07-24 2013-11-27 Geno LLC Methods for diagnosing and treating a heart condition in a patient
US8607785B2 (en) 2008-08-21 2013-12-17 Geno Llc Systems and devices for generating nitric oxide
US10780241B2 (en) 2008-08-21 2020-09-22 Vero Biotech LLC Devices and methods for minimizing and treating high-altitude sickness
US8701657B2 (en) 2008-08-21 2014-04-22 Geno Llc Systems for generating nitric oxide
US10960168B2 (en) 2008-08-21 2021-03-30 Vero Biotech LLC Delivery of high concentration nitric oxide
EP2362810A4 (en) 2008-09-22 2013-09-11 Geno Llc CONVERSION OF NITROGEN DIOXIDE (NO2) TO NITROGEN MONOXIDE (NO)
JP5878866B2 (ja) 2009-06-22 2016-03-08 ゲノ エルエルシー 一酸化窒素治療
WO2011063335A1 (en) * 2009-11-20 2011-05-26 Geno Llc Nitric oxide delivery system
US20120093948A1 (en) * 2009-11-20 2012-04-19 Fine David H Nitric Oxide Treatments
EP2563435B1 (en) 2010-04-26 2020-06-03 VERO Biotech LLC Delivery of ultra pure nitric oxide (no)
US8268252B2 (en) 2010-04-26 2012-09-18 Geno Llc Nitrosyl special connector
USD688352S1 (en) 2010-04-27 2013-08-20 Geno Llc Female gas connector
USD679366S1 (en) 2010-04-27 2013-04-02 Geno Llc Male gas connector
JP2014527025A (ja) 2011-05-27 2014-10-09 ゲノ エルエルシー 吸入用一酸化窒素を用いて血管反応性を決定する方法
CA3211190A1 (en) 2014-10-20 2016-04-28 Vero Biotech LLC Nitrogen dioxide storage cassette

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006063215A2 (en) * 2004-12-08 2006-06-15 Biomarin Pharmaceutical Inc. Methods and compositions for the treatment of pulmonary hypertension of the newborn
WO2011002606A1 (en) * 2009-06-30 2011-01-06 Ikaria Holdings, Inc. Methods of identifying a patient population eligible for treatment with nitric oxide via inhalation
WO2012075420A1 (en) * 2010-12-03 2012-06-07 Geno Llc Nitric oxide treatments
WO2012151701A1 (en) * 2011-05-10 2012-11-15 Université Laval / Vice-Rectorat À La Recherche Et À La Création Methods for the treatment and diagnostic of pulmonary arterial hypertension

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Oudiz, R. et al., Advances in Pulmonary Hypertension: Official Journal of the Pulmonary Hypertension Association, 2005, vol. 4, no. 3, pages 15-25. *

Also Published As

Publication number Publication date
JP2017165731A (ja) 2017-09-21
AU2012262534A1 (en) 2013-12-12
JP2019131556A (ja) 2019-08-08
EP2713723A4 (en) 2015-03-25
EP2713723A1 (en) 2014-04-09
EP2713723B1 (en) 2018-09-12
CA2837341C (en) 2021-10-19
JP2014527025A (ja) 2014-10-09
CA2837341A1 (en) 2012-12-06
WO2012166534A1 (en) 2012-12-06
US20130309328A1 (en) 2013-11-21
US11154210B2 (en) 2021-10-26

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FGA Letters patent sealed or granted (standard patent)
HB Alteration of name in register

Owner name: VERO BIOTECH LLC.

Free format text: FORMER NAME(S): GENO LLC

MK14 Patent ceased section 143(a) (annual fees not paid) or expired