CA2819378A1 - Interventions et diagnostic associe a irak - Google Patents

Interventions et diagnostic associe a irak Download PDF

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Publication number
CA2819378A1
CA2819378A1 CA2819378A CA2819378A CA2819378A1 CA 2819378 A1 CA2819378 A1 CA 2819378A1 CA 2819378 A CA2819378 A CA 2819378A CA 2819378 A CA2819378 A CA 2819378A CA 2819378 A1 CA2819378 A1 CA 2819378A1
Authority
CA
Canada
Prior art keywords
mir
nnir
adiponectin
metabolic syndrome
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
CA2819378A
Other languages
English (en)
Inventor
Paul Holvoet
Maarten Hulsmans
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
KU Leuven Research and Development
Original Assignee
KU Leuven Research and Development
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by KU Leuven Research and Development filed Critical KU Leuven Research and Development
Publication of CA2819378A1 publication Critical patent/CA2819378A1/fr
Withdrawn legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/106Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/112Disease subtyping, staging or classification
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/158Expression markers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/178Oligonucleotides characterized by their use miRNA, siRNA or ncRNA
CA2819378A 2010-12-02 2011-11-30 Interventions et diagnostic associe a irak Withdrawn CA2819378A1 (fr)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US45892710P 2010-12-02 2010-12-02
US45889610P 2010-12-02 2010-12-02
US61/458,927 2010-12-02
US61/458,896 2010-12-02
US201161462874P 2011-02-08 2011-02-08
US61/462,874 2011-02-08
US201161572630P 2011-07-18 2011-07-18
US61/572,630 2011-07-18
PCT/EP2011/071394 WO2012072685A1 (fr) 2010-12-02 2011-11-30 Interventions et diagnostic associé à irak

Publications (1)

Publication Number Publication Date
CA2819378A1 true CA2819378A1 (fr) 2012-06-07

Family

ID=45218686

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2819378A Withdrawn CA2819378A1 (fr) 2010-12-02 2011-11-30 Interventions et diagnostic associe a irak

Country Status (3)

Country Link
EP (1) EP2561102A1 (fr)
CA (1) CA2819378A1 (fr)
WO (1) WO2012072685A1 (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITRM20110685A1 (it) 2011-12-23 2013-06-24 Internat Ct For Genetic En Gineering And Microrna per la rigenerazione cardiaca attraverso l induzione della proliferazione dei miociti cardiaci
US20140024024A1 (en) * 2012-07-17 2014-01-23 General Electric Company Methods of detecting dna, rna and protein in biological samples
EP2890789A1 (fr) * 2012-08-31 2015-07-08 Aptamir Therapeutics, Inc. Modulateurs de type microarn de l'inflammation viscérale chronique
US10242756B2 (en) 2012-09-21 2019-03-26 Ethicon Endo-Surgery, Inc. Systems and methods for predicting metabolic and bariatric surgery outcomes
EP2898101A4 (fr) 2012-09-21 2016-08-03 Ethicon Endo Surgery Inc Prédicteurs cliniques de la perte de poids
SG11201707752SA (en) 2015-04-22 2017-11-29 Rigel Pharmaceuticals Inc Pyrazole compounds and method for making and using the compounds
JP2020109355A (ja) * 2017-04-24 2020-07-16 明子 秦 Aimを指標とするメタボリック・シンドロームの発症予測方法
JP2021531278A (ja) * 2018-07-20 2021-11-18 レグルス セラピューティクス インコーポレイテッド オリゴヌクレオチドの経口送達のための方法
CN109680058A (zh) * 2019-01-10 2019-04-26 华中科技大学同济医学院附属协和医院 miR-101水平检测在糖尿病微血管病变诊断试剂中的应用及试剂盒
TW202122393A (zh) 2019-08-30 2021-06-16 美商雷傑製藥公司 吡唑化合物,其配製物以及使用該化合物和/或配製物之方法
US10844383B1 (en) 2019-09-18 2020-11-24 Dasman Diabetes Institute Microrna dyslipidemia inhibitor
US11058710B1 (en) 2020-02-14 2021-07-13 Dasman Diabetes Institute MicroRNA ANGPTL3 inhibitor

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6040138A (en) 1995-09-15 2000-03-21 Affymetrix, Inc. Expression monitoring by hybridization to high density oligonucleotide arrays
US5800992A (en) 1989-06-07 1998-09-01 Fodor; Stephen P.A. Method of detecting nucleic acids
EP0880598A4 (fr) 1996-01-23 2005-02-23 Affymetrix Inc Evaluation rapide de difference d'abondance d'acides nucleiques, avec un systeme d'oligonucleotides haute densite
US7348181B2 (en) 1997-10-06 2008-03-25 Trustees Of Tufts College Self-encoding sensor with microspheres
WO1999023254A1 (fr) 1997-10-31 1999-05-14 Affymetrix, Inc. Profils d'expression dans des organes d'adultes et de foetus
US6020135A (en) 1998-03-27 2000-02-01 Affymetrix, Inc. P53-regulated genes
DE60000583T3 (de) 1999-05-19 2009-04-30 Eppendorf Array Technologies Verfahren zur identifizierung und/oder quantifizierung einer zielverbindung
US7371516B1 (en) 1999-07-16 2008-05-13 Rosetta Inpharmatics Llc Methods for determining the specificity and sensitivity of oligonucleo tides for hybridization
US7244559B2 (en) 1999-09-16 2007-07-17 454 Life Sciences Corporation Method of sequencing a nucleic acid
US7211390B2 (en) 1999-09-16 2007-05-01 454 Life Sciences Corporation Method of sequencing a nucleic acid
JP2002262876A (ja) 2001-03-07 2002-09-17 Ngk Insulators Ltd 高感度な核酸のハイブリダイゼーション方法、及びその方法を用いた遺伝子解析方法
US7047141B2 (en) 2001-03-22 2006-05-16 Ge Healthcare Bio-Sciences Ab Ratio-based oligonucleotide probe selection
WO2002090599A1 (fr) 2001-05-09 2002-11-14 Genetic Id, Inc. Systeme de microtitration universel
US7189509B2 (en) 2001-08-16 2007-03-13 Zhifeng Shao Analysis of gene expression profiles using sequential hybridization
US7439346B2 (en) 2001-10-12 2008-10-21 Perkinelmer Las Inc. Nucleic acids arrays and methods of use therefor
CA2463725A1 (fr) 2001-10-12 2003-11-06 Spectral Genomics, Inc. Compilations d'acides nucleiques, reseaux et procedes d'utilisation de ceux-ci
US7221785B2 (en) 2002-05-21 2007-05-22 Agilent Technologies, Inc. Method and system for measuring a molecular array background signal from a continuous background region of specified size
US7031845B2 (en) 2002-07-19 2006-04-18 University Of Chicago Method for determining biological expression levels by linear programming
CA2463719A1 (fr) 2003-04-05 2004-10-05 F. Hoffmann-La Roche Ag Analogues de nucleotides possedant des cycles a six chainons
US7347921B2 (en) 2003-07-17 2008-03-25 Agilent Technologies, Inc. Apparatus and method for threading a biopolymer through a nanopore
US7353116B2 (en) 2003-07-31 2008-04-01 Agilent Technologies, Inc. Chemical array with test dependent signal reading or processing
US7302348B2 (en) 2004-06-02 2007-11-27 Agilent Technologies, Inc. Method and system for quantifying and removing spatial-intensity trends in microarray data
US7323308B2 (en) 2004-09-03 2008-01-29 Affymetrix, Inc. Methods of genetic analysis of E. coli
GB0809069D0 (en) 2008-05-19 2008-06-25 Univ Leuven Kath Gene signatures
CN102388149A (zh) * 2009-02-02 2012-03-21 西菲伊德公司 检测败血症的方法
WO2010129919A1 (fr) 2009-05-08 2010-11-11 Research Development Foundation Expression d'arnmi dans une maladie allergique
WO2010133970A1 (fr) 2009-05-20 2010-11-25 Eth Zurich Ciblage de micro-arn pour traiter les troubles métaboliques

Also Published As

Publication number Publication date
WO2012072685A1 (fr) 2012-06-07
EP2561102A1 (fr) 2013-02-27

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Effective date: 20131115