CA2819013C - Apparatus and methods for aliquotting frozen samples - Google Patents

Apparatus and methods for aliquotting frozen samples Download PDF

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Publication number
CA2819013C
CA2819013C CA2819013A CA2819013A CA2819013C CA 2819013 C CA2819013 C CA 2819013C CA 2819013 A CA2819013 A CA 2819013A CA 2819013 A CA2819013 A CA 2819013A CA 2819013 C CA2819013 C CA 2819013C
Authority
CA
Canada
Prior art keywords
sample
frozen
location
aliquot
samples
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA2819013A
Other languages
English (en)
French (fr)
Other versions
CA2819013A1 (en
Inventor
Dale N. Larson
Stephen L. Bellio
John Slusarz
Original Assignee
Charles Stark Draper Laboratory Inc
Harvard University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Charles Stark Draper Laboratory Inc, Harvard University filed Critical Charles Stark Draper Laboratory Inc
Publication of CA2819013A1 publication Critical patent/CA2819013A1/en
Application granted granted Critical
Publication of CA2819013C publication Critical patent/CA2819013C/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/02—Devices for withdrawing samples
    • G01N1/04—Devices for withdrawing samples in the solid state, e.g. by cutting
    • G01N1/08—Devices for withdrawing samples in the solid state, e.g. by cutting involving an extracting tool, e.g. core bit
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/286—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q involving mechanical work, e.g. chopping, disintegrating, compacting, homogenising
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/42—Low-temperature sample treatment, e.g. cryofixation

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
CA2819013A 2010-12-01 2011-11-17 Apparatus and methods for aliquotting frozen samples Expired - Fee Related CA2819013C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US41868810P 2010-12-01 2010-12-01
US61/418,688 2010-12-01
PCT/US2011/061214 WO2012074771A2 (en) 2010-12-01 2011-11-17 Apparatus and methods for aliquotting frozen samples

Publications (2)

Publication Number Publication Date
CA2819013A1 CA2819013A1 (en) 2012-06-07
CA2819013C true CA2819013C (en) 2020-04-14

Family

ID=45044753

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2819013A Expired - Fee Related CA2819013C (en) 2010-12-01 2011-11-17 Apparatus and methods for aliquotting frozen samples

Country Status (8)

Country Link
US (1) US20140335554A1 (enExample)
EP (1) EP2646792B1 (enExample)
JP (2) JP2013545105A (enExample)
CN (1) CN103370610B (enExample)
AU (1) AU2011337043A1 (enExample)
BR (1) BR112013013505A2 (enExample)
CA (1) CA2819013C (enExample)
WO (1) WO2012074771A2 (enExample)

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US9032854B2 (en) 2011-12-21 2015-05-19 Sakura Finetek U.S.A., Inc. Reciprocating microtome drive system
US9134202B2 (en) 2012-01-26 2015-09-15 Cryoxtract Instruments, Llc Robotic end effector for frozen aliquotter and methods of taking a frozen aliquot from biological samples
US20140267713A1 (en) * 2013-03-15 2014-09-18 Cryoxtract Instruments, Llc Machine Vision System for Frozen Aliquotter for Biological Samples
US20130286192A1 (en) * 2012-04-30 2013-10-31 Cryoxtract Instruments, Llc Machine Vision System for Frozen Aliquotter for Biological Samples
US12157595B2 (en) * 2012-05-03 2024-12-03 Vanrx Pharmasystems Inc. Cover removal system for use in controlled environment enclosures
US12065347B2 (en) * 2012-05-03 2024-08-20 Vanrx Pharmasystems Inc. Cover removal system for use in controlled environment enclosures
BR112015001460A2 (pt) * 2012-07-24 2017-07-04 Cryoxtract Instr Llc sonda de escavação, sistemas para colher núcleo de amostras congelados de uma pluralidade de amostras congeladas, para coletar alíquotas congeladas de amostras biológicas congeladas contidas em contêineres de amostras, para armazenar amostras de tecido congeladas, métodos de colher um núcleo de amostra congelada de uma amostra congelada, para aumentar a probabilidade de um operador usar apenas as sondas de escavação, para preparar e amostrar uma amostra de tecido em um contêiner de amostra de tecido, e de armazenamento de uma amostra de tecido, dispositivo portátil de escavação, bandeja, contêiner de amostra de tecido, kit para preparação de u,a a,ostra de tecido, transporte de tecido para suportar a amostra de tecido, e, combinação de transporte de tecido e dispositivo de escavação.
FI10181U1 (fi) 2013-04-17 2013-08-14 Konecranes Oyj Tarttuja kuormankäsittelylaitetta varten ja nosturi
CA2910981A1 (en) * 2013-05-04 2014-11-13 Cryoxtract Instruments, Llc Targeting systems and methods for frozen aliquotter for biological samples
CN103636737B (zh) * 2013-10-24 2016-05-11 杨公明 一种羊胎盘及羊水现场收集与保鲜的方法
US12392692B2 (en) 2017-03-09 2025-08-19 Hologic, Inc. Systems for automated preparation of biological specimens
CN115235841B (zh) 2017-03-09 2025-10-31 霍罗杰克股份有限公司 自动化制备生物样品的系统及方法
CN107843453B (zh) * 2017-12-21 2024-01-23 上海泽泉科技股份有限公司 可调速手持低温样本分装仪
EP3811007A1 (en) * 2018-06-20 2021-04-28 Gen-Probe Incorporated Method and apparatus for freezing dispensed droplets of liquid
US11946690B2 (en) 2019-02-17 2024-04-02 National Scientific and Technical Research Council—Argentina (CONICET) System for accessing biological samples in a cryogenic Dewar vessel
CN113533762B (zh) * 2020-04-22 2025-10-24 深圳迎凯生物科技有限公司 试剂存储装置
CN111504691B (zh) * 2020-05-10 2023-03-10 淮阴师范学院 一种便携式地理信息采集装置
US11981473B2 (en) * 2020-09-27 2024-05-14 V Anrx Pharmasystems Inc. Cover removal system for use in controlled environment enclosures
CN116643025B (zh) * 2023-05-06 2024-04-02 中国地质大学（北京） 一种用于环境地质土壤检测的检测装置
CN117969196A (zh) * 2023-10-08 2024-05-03 四川国际旅行卫生保健中心(成都海关口岸门诊部) 一种无接触式粪便包虫的样本预处理设备
CN122294991A (zh) * 2023-11-22 2026-06-26 米特根有限公司 用于快速升温细胞和其他生物材料的系统、方法和装置
WO2026043570A1 (en) * 2024-08-23 2026-02-26 Conceivable Life Sciences Inc. Automated plunging system for rapid vitrification

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JPS6166944A (ja) * 1984-09-11 1986-04-05 Nitsuteku Eng:Kk 血清試料の秤取方法及びその装置
US6117130A (en) * 1998-09-24 2000-09-12 Abiomed, Inc. Coring device for myocardial revascularization
TW388790B (en) * 1999-04-13 2000-05-01 Inst Of Unclear Energy Res Roc An automatic sampling method and facility for the heterogeneous materials
US20040085443A1 (en) * 2000-12-13 2004-05-06 Kallioniemi Olli P Method and system for processing regions of interest for objects comprising biological material
US20020129975A1 (en) * 2001-01-17 2002-09-19 Barta Ernest G. Ice auger system
US6635414B2 (en) * 2001-05-22 2003-10-21 Integrated Biosystems, Inc. Cryopreservation system with controlled dendritic freezing front velocity
GB0325483D0 (en) * 2003-10-31 2003-12-03 Plasmacute As Assay
JP4451263B2 (ja) * 2004-10-13 2010-04-14 エーザイ・アール・アンド・ディー・マネジメント株式会社 試料摘出装置
US8448456B2 (en) * 2006-01-13 2013-05-28 President And Fellows Of Harvard College Systems, methods and devices for frozen sample distribution
US7823818B2 (en) * 2007-10-17 2010-11-02 Max-Planck-Gessellschaft zur Foerderung der Wissenschafter E.V. System and method for producing weighed portions of powder from at least one biological material at cryotemperatures
WO2009123000A1 (ja) * 2008-03-31 2009-10-08 シスメックス株式会社 細胞処理装置、試料調製装置および細胞分析装置
JP5530613B2 (ja) * 2008-10-06 2014-06-25 シスメックス株式会社 検体処理システム及び検体搬送システム
JP5203889B2 (ja) * 2008-10-28 2013-06-05 シスメックス株式会社 検体分析装置及び検体分析方法

Also Published As

Publication number Publication date
AU2011337043A1 (en) 2013-06-13
EP2646792A2 (en) 2013-10-09
US20140335554A1 (en) 2014-11-13
WO2012074771A3 (en) 2012-08-16
EP2646792B1 (en) 2019-07-10
CA2819013A1 (en) 2012-06-07
CN103370610A (zh) 2013-10-23
JP2013545105A (ja) 2013-12-19
BR112013013505A2 (pt) 2016-09-06
CN103370610B (zh) 2016-08-10
JP2016122018A (ja) 2016-07-07
WO2012074771A2 (en) 2012-06-07

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Effective date: 20171107

MKLA Lapsed

Effective date: 20201117