CA2817882C - Mirnas as biomarkers for distinguishing benign from malignant thyroid neoplasms - Google Patents

Mirnas as biomarkers for distinguishing benign from malignant thyroid neoplasms Download PDF

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Publication number
CA2817882C
CA2817882C CA2817882A CA2817882A CA2817882C CA 2817882 C CA2817882 C CA 2817882C CA 2817882 A CA2817882 A CA 2817882A CA 2817882 A CA2817882 A CA 2817882A CA 2817882 C CA2817882 C CA 2817882C
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mir
hsa
mirna
thyroid
mirnas
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French (fr)
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CA2817882A1 (en
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Sylvie Beaudenon-Huibregtse
Ashish Choudhary
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INTERPACE DIAGNOSTICS LLC
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INTERPACE DIAGNOSTICS LLC
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/112—Disease subtyping, staging or classification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/178—Oligonucleotides characterized by their use miRNA, siRNA or ncRNA

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • Biophysics (AREA)
  • Oncology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
CA2817882A 2010-11-17 2011-11-17 Mirnas as biomarkers for distinguishing benign from malignant thyroid neoplasms Active CA2817882C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US41477810P 2010-11-17 2010-11-17
US61/414,778 2010-11-17
PCT/US2011/061237 WO2012068400A2 (en) 2010-11-17 2011-11-17 Mirnas as biomarkers for distinguishing benign from malignant thyroid neoplasms

Publications (2)

Publication Number Publication Date
CA2817882A1 CA2817882A1 (en) 2012-05-24
CA2817882C true CA2817882C (en) 2022-08-23

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ID=45217687

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2817882A Active CA2817882C (en) 2010-11-17 2011-11-17 Mirnas as biomarkers for distinguishing benign from malignant thyroid neoplasms

Country Status (9)

Country Link
US (4) US10150999B2 (https=)
EP (2) EP2772550B1 (https=)
JP (1) JP6155194B2 (https=)
AU (1) AU2011329772B2 (https=)
BR (1) BR112013012265A2 (https=)
CA (1) CA2817882C (https=)
ES (1) ES2629890T3 (https=)
IL (2) IL226356B (https=)
WO (1) WO2012068400A2 (https=)

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US10446272B2 (en) 2009-12-09 2019-10-15 Veracyte, Inc. Methods and compositions for classification of samples
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CN109055541B (zh) * 2018-09-26 2020-08-28 上海市精神卫生中心（上海市心理咨询培训中心） Ad所致mci诊断标志物及其应用
CN110241215B (zh) * 2019-07-03 2020-05-19 上海润安医学科技有限公司 一种用于检测甲状腺结节良恶性相关基因变异的引物及试剂盒
CN110468204A (zh) * 2019-08-09 2019-11-19 深圳市第二人民医院 生物标志物及其在制备诊断ptc的产品中的应用
WO2022055316A1 (ko) * 2020-09-14 2022-03-17 연세대학교 산학협력단 양성 종양 또는 결절로부터 암을 구분하기 위한 바이오마커
KR102426397B1 (ko) * 2020-09-14 2022-07-28 연세대학교 산학협력단 암 진단의 정확도를 높이기 위한 유전자 발현 수준의 보정 방법
RU2757347C1 (ru) * 2021-02-08 2021-10-13 Сергей Евгеньевич Титов Способ дифференциальной диагностики узловых образований щитовидной железы человека
CN116769922B (zh) * 2023-08-24 2023-11-24 四川大学华西医院 检测循环sEV RNA试剂的用途、试剂盒和诊断系统
CN116987791B (zh) * 2023-09-22 2023-12-22 润安医学科技(苏州)有限公司 一组血浆标志物在甲状腺结节良恶性鉴别中的应用
CN118248319B (zh) * 2024-02-20 2024-12-03 上海睿璟生物科技有限公司 基于基因组变异与异常表达结合的甲状腺结节良恶性辅助诊断系统
CN121518655A (zh) * 2026-01-16 2026-02-13 山东第一医科大学(山东省医学科学院) 用于甲状腺乳头状癌淋巴转移评估的标志物、试剂盒及方法

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