CA2814441A1 - Microorganisms for 1,3-propanediol production using high glycerine concentration - Google Patents

Microorganisms for 1,3-propanediol production using high glycerine concentration Download PDF

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Publication number
CA2814441A1
CA2814441A1 CA2814441A CA2814441A CA2814441A1 CA 2814441 A1 CA2814441 A1 CA 2814441A1 CA 2814441 A CA2814441 A CA 2814441A CA 2814441 A CA2814441 A CA 2814441A CA 2814441 A1 CA2814441 A1 CA 2814441A1
Authority
CA
Canada
Prior art keywords
glycerine
metabolism
strain
clostridium acetobutylicum
population
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2814441A
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English (en)
French (fr)
Inventor
Rainer Figge
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Metabolic Explorer SA
Original Assignee
Metabolic Explorer SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Metabolic Explorer SA filed Critical Metabolic Explorer SA
Publication of CA2814441A1 publication Critical patent/CA2814441A1/en
Abandoned legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/32—Processes using, or culture media containing, lower alkanols, i.e. C1 to C6
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/18—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic polyhydric
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/145—Clostridium

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  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Plant Pathology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
CA2814441A 2010-11-10 2011-11-10 Microorganisms for 1,3-propanediol production using high glycerine concentration Abandoned CA2814441A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US41216210P 2010-11-10 2010-11-10
EP10306234 2010-11-10
US61/412,162 2010-11-10
EP10306234.5 2010-11-10
PCT/EP2011/069789 WO2012062832A1 (en) 2010-11-10 2011-11-10 Microorganisms for 1,3-propanediol production using high glycerine concentration

Publications (1)

Publication Number Publication Date
CA2814441A1 true CA2814441A1 (en) 2012-05-18

Family

ID=43828229

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2814441A Abandoned CA2814441A1 (en) 2010-11-10 2011-11-10 Microorganisms for 1,3-propanediol production using high glycerine concentration

Country Status (10)

Country Link
US (1) US20130177956A1 (https=)
EP (2) EP2638172A1 (https=)
JP (1) JP2013545461A (https=)
KR (1) KR20140005170A (https=)
CN (1) CN103298945A (https=)
AR (1) AR083799A1 (https=)
BR (1) BR112013011417A2 (https=)
CA (1) CA2814441A1 (https=)
TW (1) TWI542685B (https=)
WO (1) WO2012062832A1 (https=)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015035266A1 (en) * 2013-09-06 2015-03-12 The Curators Of The University Of Missouri Conversion of glycerol to 1,3-propanediol under haloalkaline conditions
KR20190026851A (ko) 2016-07-08 2019-03-13 에보니크 데구사 게엠베하 당 포스포트랜스퍼라제 시스템 (pts)을 코딩하는 유전자를 포함하는 미생물에 의한 메티오닌 또는 그의 히드록시 유사체 형태의 발효적 생산을 위한 방법
CN106190901B (zh) 2016-07-15 2020-06-26 上海交通大学 一种菌及其获取方法和应用
CN106978380A (zh) * 2016-12-14 2017-07-25 天津科技大学 一株高木糖耐性肺炎克雷伯氏菌株及其构建方法
ES2893002T3 (es) * 2017-02-20 2022-02-07 Metabolic Explorer Sa Consorcio microbiano que comprende clostridia para la producción de 1,3-propanodiol a partir de glicerol
EP3438270A1 (en) 2017-08-04 2019-02-06 Metabolic Explorer Microorganism and method for improved 1,3-propanediol production by fermentation on a culture medium with high glycerine content
EP3692159A1 (en) 2017-10-02 2020-08-12 Metabolic Explorer Method for producing organic acid salts from fermentation broth
US11814663B2 (en) * 2018-08-10 2023-11-14 Metabolic Explorer Microorganisms with improved 1,3-propanediol and butyric acid production
CN112358986B (zh) * 2020-11-09 2022-10-21 华南理工大学 一种丁酸梭菌及其在固定化发酵生产1，3-丙二醇的应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2796081B1 (fr) 1999-07-09 2003-09-26 Agronomique Inst Nat Rech Procede de preparation du 1,3-propanediol par un micro-organisme recombinant en l'absence de coenzyme b12 ou de l'un de ses precurseurs
CN1327001C (zh) 2005-06-03 2007-07-18 清华大学 利用生物柴油副产物甘油生产1,3－丙二醇的方法
CN101500565A (zh) * 2006-06-29 2009-08-05 弗特克斯药品有限公司 毒蕈碱性受体的调节剂
WO2008040387A1 (en) 2006-10-03 2008-04-10 Metabolic Explorer Process for chromosomal integration and dna sequence replacement in clostridia
WO2008052595A1 (en) 2006-10-31 2008-05-08 Metabolic Explorer Process for the biological production of 1,3-propanediol from glycerol with high yield
KR101543485B1 (ko) 2007-11-30 2015-08-10 메타볼릭 익스플로러 발효 브로쓰로부터 알콜을 정제하는 방법
ES2401155T3 (es) 2008-10-03 2013-04-17 Metabolic Explorer Procedimiento para la purificación de un alcohol a partir de un caldo de fermentación que utiliza un evaporador de película descendente, de película renovada, de película fina o de recorrido corto
EP2248904A1 (en) * 2009-05-05 2010-11-10 Metabolic Explorer Continuous culture for 1,3-propanediol production using high glycerine concentration

Also Published As

Publication number Publication date
WO2012062832A1 (en) 2012-05-18
CN103298945A (zh) 2013-09-11
JP2013545461A (ja) 2013-12-26
TW201226563A (en) 2012-07-01
KR20140005170A (ko) 2014-01-14
AR083799A1 (es) 2013-03-20
US20130177956A1 (en) 2013-07-11
EP3012325A1 (en) 2016-04-27
EP2638172A1 (en) 2013-09-18
BR112013011417A2 (pt) 2017-04-04
TWI542685B (zh) 2016-07-21

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FZDE Discontinued

Effective date: 20171110