CA2802645C - Assay device having controllable sample size - Google Patents

Assay device having controllable sample size Download PDF

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Publication number
CA2802645C
CA2802645C CA2802645A CA2802645A CA2802645C CA 2802645 C CA2802645 C CA 2802645C CA 2802645 A CA2802645 A CA 2802645A CA 2802645 A CA2802645 A CA 2802645A CA 2802645 C CA2802645 C CA 2802645C
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CA
Canada
Prior art keywords
zone
sample
reagent
detection
flow path
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA2802645A
Other languages
English (en)
French (fr)
Other versions
CA2802645A1 (en
Inventor
Edward R. Scalice
Philip C. Hosimer
Zhong Ding
James D. Kanaley
David A. Tomasso
Daniel P. Salotto
Timothy C. Warren
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ortho Clinical Diagnostics Inc
Original Assignee
Ortho Clinical Diagnostics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho Clinical Diagnostics Inc filed Critical Ortho Clinical Diagnostics Inc
Publication of CA2802645A1 publication Critical patent/CA2802645A1/en
Application granted granted Critical
Publication of CA2802645C publication Critical patent/CA2802645C/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5302—Apparatus specially adapted for immunological test procedures
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/08—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a stream of discrete samples flowing along a tube system, e.g. flow injection analysis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54386—Analytical elements
    • G01N33/54387—Immunochromatographic test strips
    • G01N33/54388—Immunochromatographic test strips based on lateral flow

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • General Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CA2802645A 2012-01-20 2013-01-18 Assay device having controllable sample size Active CA2802645C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261588899P 2012-01-20 2012-01-20
US61/588,899 2012-01-20

Publications (2)

Publication Number Publication Date
CA2802645A1 CA2802645A1 (en) 2013-07-20
CA2802645C true CA2802645C (en) 2020-08-11

Family

ID=47630176

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2802645A Active CA2802645C (en) 2012-01-20 2013-01-18 Assay device having controllable sample size

Country Status (7)

Country Link
US (2) US10712340B2 (https=)
EP (1) EP2618152B1 (https=)
JP (1) JP6395998B2 (https=)
KR (1) KR20130085992A (https=)
CN (1) CN103212454B (https=)
BR (1) BR102013001324A2 (https=)
CA (1) CA2802645C (https=)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2802260C (en) 2012-01-20 2021-03-30 Ortho-Clinical Diagnostics, Inc. Controlling fluid flow through an assay device
EP2618149B1 (en) 2012-01-20 2016-07-27 Ortho-Clinical Diagnostics, Inc. Assay device having uniform flow around corners
JP2014173937A (ja) * 2013-03-07 2014-09-22 Toshiba Corp 半導体マイクロ分析チップ及び検体流動方法
US10071373B2 (en) * 2014-08-08 2018-09-11 Ortho-Clinical Diagnostics, Inc. Lateral-flow assay device having flow constrictions
US10073091B2 (en) 2014-08-08 2018-09-11 Ortho-Clinical Diagnostics, Inc. Lateral flow assay device
CN104880562A (zh) * 2015-04-08 2015-09-02 上海盛复源生物医药有限公司 一种l-fabp快速检测试剂及其制备方法
CN104880563A (zh) * 2015-04-08 2015-09-02 上海盛复源生物医药有限公司 一种ngal快速检测试剂及其制备方法
WO2016187244A1 (en) 2015-05-19 2016-11-24 Ortho-Clinical Diagnostics, Inc. Method of improving liquid sample flow in assay device
CN108431603B (zh) * 2016-12-28 2020-04-21 纽勤有限公司 流体限位器筒式组件及其使用方法
USD834721S1 (en) 2017-03-03 2018-11-27 Neogen Corporation Assay cartridge
US20230294086A1 (en) * 2020-07-30 2023-09-21 Colorado State University Research Foundation Capillary-driven colorimetric assay devices
CN116764701A (zh) * 2023-05-12 2023-09-19 东南大学 基于液态金属电极的液滴分选微流控芯片及其制备方法

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ATE195022T1 (de) 1987-04-27 2000-08-15 Unilever Nv Spezifische bindungstestverfahren
US5120643A (en) 1987-07-13 1992-06-09 Abbott Laboratories Process for immunochromatography with colloidal particles
AU2684488A (en) 1988-06-27 1990-01-04 Carter-Wallace, Inc. Test device and method for colored particle immunoassay
US5252496A (en) 1989-12-18 1993-10-12 Princeton Biomeditech Corporation Carbon black immunochemical label
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US5607863A (en) * 1991-05-29 1997-03-04 Smithkline Diagnostics, Inc. Barrier-controlled assay device
IL108159A (en) 1993-12-23 1998-02-08 Orgenics Ltd Apparatus for separation, concentration and detection of target molecules in liquid sample
JP3552272B2 (ja) 1994-05-27 2004-08-11 帝国臓器製薬株式会社 免疫化学的簡易アッセイ方法および装置
AU2537895A (en) 1994-05-27 1995-12-21 Teikoku Hormone Mfg. Co., Ltd. Simple method and device for immunochemical assay
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SE9704935D0 (sv) * 1997-12-30 1997-12-30 Pharmacia & Upjohn Diag Ab Analysmetod med partiklar
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SE521415C2 (sv) 1998-02-17 2003-10-28 Hans Goeran Evald Martin Metod för att framställa en gassensortillhörig detektor, samt en detektor framställd enligt metoden
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EP1358987A3 (en) 1998-10-14 2004-03-03 Gyros AB A replication matrix
SE9903011D0 (sv) 1999-08-26 1999-08-26 Aamic Ab Sätt att framställa en plastprodukt och ett härför utnyttjat plastproduktformande arrangemang
US6733682B1 (en) 1999-09-10 2004-05-11 Amic Ab Method for the manufacturing of a matrix and a matrix manufactured according to the method
SE0201738D0 (sv) 2002-06-07 2002-06-07 Aamic Ab Micro-fluid structures
FR2853077B1 (fr) 2003-03-28 2005-12-30 Vedalab Procedes immunochromatographiques en phase solide
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SE527036C2 (sv) 2004-06-02 2005-12-13 Aamic Ab Analysanordning med reglerat flöde och motsvarande förfarande
US7972872B2 (en) 2004-06-07 2011-07-05 Denka Seiken Co., Ltd. Chromatography detection apparatus, detection method, and kit utilizing the same
SE529254C2 (sv) 2005-06-17 2007-06-12 Aamic Ab Optiskt testsystem
SE528233C2 (sv) 2005-06-20 2006-09-26 Aamic Ab Metod och medel för att åstadkomma vätsketransport
CA2614771A1 (en) * 2005-08-31 2007-03-08 Egomedical Technologies Ag Analyte test system using non-enzymatic analyte recognition elements
SE529711C2 (sv) 2006-03-22 2007-11-06 Aamic Ab Fluorescensläsare
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CN102414561A (zh) * 2009-04-28 2012-04-11 创新实验室技术公司 侧流式免疫层析测定设备
JP5132664B2 (ja) * 2009-12-07 2013-01-30 富士フイルム株式会社 イムノクロマトグラフ方法
KR20130085994A (ko) 2012-01-20 2013-07-30 오르토-클리니칼 다이아그노스틱스, 인코포레이티드 다수의 시약 셀을 갖는 분석 장치
KR20130085995A (ko) 2012-01-20 2013-07-30 오르토-클리니칼 다이아그노스틱스, 인코포레이티드 증가된 감도를 갖는 저체적 분석 장치
CA2802260C (en) 2012-01-20 2021-03-30 Ortho-Clinical Diagnostics, Inc. Controlling fluid flow through an assay device
WO2013109821A1 (en) 2012-01-20 2013-07-25 Ortho-Clinical Diagnostics, Inc. Assay device having multiplexing

Also Published As

Publication number Publication date
EP2618152B1 (en) 2015-07-01
US20200300841A1 (en) 2020-09-24
JP6395998B2 (ja) 2018-09-26
EP2618152A1 (en) 2013-07-24
KR20130085992A (ko) 2013-07-30
CN103212454A (zh) 2013-07-24
US11921107B2 (en) 2024-03-05
BR102013001324A2 (pt) 2015-07-28
JP2013148582A (ja) 2013-08-01
US10712340B2 (en) 2020-07-14
US20130189673A1 (en) 2013-07-25
CA2802645A1 (en) 2013-07-20
CN103212454B (zh) 2019-06-04

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