CA2796213A1 - Organic peroxide compounds for microorganism inactivation - Google Patents
Organic peroxide compounds for microorganism inactivation Download PDFInfo
- Publication number
- CA2796213A1 CA2796213A1 CA2796213A CA2796213A CA2796213A1 CA 2796213 A1 CA2796213 A1 CA 2796213A1 CA 2796213 A CA2796213 A CA 2796213A CA 2796213 A CA2796213 A CA 2796213A CA 2796213 A1 CA2796213 A1 CA 2796213A1
- Authority
- CA
- Canada
- Prior art keywords
- composition
- solution
- organic peroxide
- 6alkyl
- multifunctional organic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- -1 Organic peroxide compounds Chemical class 0.000 title claims 10
- 244000005700 microbiome Species 0.000 title claims 8
- 230000002779 inactivation Effects 0.000 title claims 2
- 150000001451 organic peroxides Chemical class 0.000 claims abstract 27
- 229910052799 carbon Inorganic materials 0.000 claims abstract 9
- 108020004707 nucleic acids Proteins 0.000 claims abstract 5
- 150000007523 nucleic acids Chemical class 0.000 claims abstract 5
- 102000039446 nucleic acids Human genes 0.000 claims abstract 5
- 238000000034 method Methods 0.000 claims 63
- 239000000203 mixture Substances 0.000 claims 28
- 239000000243 solution Substances 0.000 claims 27
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 claims 10
- 229910052739 hydrogen Inorganic materials 0.000 claims 8
- 125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 claims 7
- 125000004123 n-propyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])* 0.000 claims 6
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 claims 5
- 125000004191 (C1-C6) alkoxy group Chemical group 0.000 claims 5
- 125000000882 C2-C6 alkenyl group Chemical group 0.000 claims 5
- 125000003320 C2-C6 alkenyloxy group Chemical group 0.000 claims 5
- 125000003118 aryl group Chemical group 0.000 claims 5
- 125000001072 heteroaryl group Chemical group 0.000 claims 5
- 125000000592 heterocycloalkyl group Chemical group 0.000 claims 5
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 claims 5
- 125000006273 (C1-C3) alkyl group Chemical group 0.000 claims 2
- 125000006603 (C1-C3) alkylaminosulfonyl group Chemical group 0.000 claims 2
- 125000006595 (C1-C3) alkylsulfinyl group Chemical group 0.000 claims 2
- 125000006594 (C1-C3) alkylsulfony group Chemical group 0.000 claims 2
- 125000006274 (C1-C3)alkoxy group Chemical group 0.000 claims 2
- 125000004454 (C1-C6) alkoxycarbonyl group Chemical group 0.000 claims 2
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 claims 2
- 241000700605 Viruses Species 0.000 claims 2
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 claims 2
- 238000004113 cell culture Methods 0.000 claims 2
- 239000003638 chemical reducing agent Substances 0.000 claims 2
- 125000004093 cyano group Chemical group *C#N 0.000 claims 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 2
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 claims 2
- 150000002978 peroxides Chemical group 0.000 claims 2
- 239000008194 pharmaceutical composition Substances 0.000 claims 2
- 125000006656 (C2-C4) alkenyl group Chemical group 0.000 claims 1
- XYFYIMMQLFFGKB-UHFFFAOYSA-N 1,1,5,5-tetrahydroperoxypentane Chemical compound OOC(OO)CCCC(OO)OO XYFYIMMQLFFGKB-UHFFFAOYSA-N 0.000 claims 1
- QXMZVCDJORAEQI-UHFFFAOYSA-N 1,1-dihydroperoxybutane Chemical compound CCCC(OO)OO QXMZVCDJORAEQI-UHFFFAOYSA-N 0.000 claims 1
- KVFLZSZJBRWQJK-UHFFFAOYSA-N 1,1-dihydroperoxyethane Chemical compound OOC(C)OO KVFLZSZJBRWQJK-UHFFFAOYSA-N 0.000 claims 1
- LPZSIYDMHWOREJ-UHFFFAOYSA-N 1,1-dihydroperoxypropane Chemical compound CCC(OO)OO LPZSIYDMHWOREJ-UHFFFAOYSA-N 0.000 claims 1
- GIHSGBFMYFAEDX-UHFFFAOYSA-N 2,2-dihydroperoxybutane Chemical compound CCC(C)(OO)OO GIHSGBFMYFAEDX-UHFFFAOYSA-N 0.000 claims 1
- KJTGWWIZKOWELB-UHFFFAOYSA-N 3,7-dihydroperoxydioxepane Chemical compound OOC1CCCC(OO)OO1 KJTGWWIZKOWELB-UHFFFAOYSA-N 0.000 claims 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims 1
- 108020004414 DNA Proteins 0.000 claims 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 1
- 239000007864 aqueous solution Substances 0.000 claims 1
- 229960005070 ascorbic acid Drugs 0.000 claims 1
- 235000010323 ascorbic acid Nutrition 0.000 claims 1
- 239000011668 ascorbic acid Substances 0.000 claims 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims 1
- 108091092356 cellular DNA Proteins 0.000 claims 1
- 239000007795 chemical reaction product Substances 0.000 claims 1
- GOQBCAPQQJUCOC-UHFFFAOYSA-N dihydroperoxymethane Chemical compound OOCOO GOQBCAPQQJUCOC-UHFFFAOYSA-N 0.000 claims 1
- 239000001257 hydrogen Substances 0.000 claims 1
- 229910052760 oxygen Inorganic materials 0.000 claims 1
- 239000001301 oxygen Substances 0.000 claims 1
- 125000002081 peroxide group Chemical group 0.000 claims 1
- 239000000047 product Substances 0.000 claims 1
- 230000000937 inactivator Effects 0.000 abstract 2
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 230000000593 degrading effect Effects 0.000 abstract 1
- 230000002906 microbiologic effect Effects 0.000 abstract 1
- 229960004854 viral vaccine Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N31/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic oxygen or sulfur compounds
- A01N31/02—Acyclic compounds
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N35/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having two bonds to hetero atoms with at the most one bond to halogen, e.g. aldehyde radical
- A01N35/02—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having two bonds to hetero atoms with at the most one bond to halogen, e.g. aldehyde radical containing aliphatically bound aldehyde or keto groups, or thio analogues thereof; Derivatives thereof, e.g. acetals
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/02—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms
- A01N43/24—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with two or more hetero atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2720/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
- C12N2720/00011—Details
- C12N2720/12011—Reoviridae
- C12N2720/12061—Methods of inactivation or attenuation
- C12N2720/12063—Methods of inactivation or attenuation by chemical treatment
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16061—Methods of inactivation or attenuation
- C12N2760/16063—Methods of inactivation or attenuation by chemical treatment
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16111—Influenzavirus A, i.e. influenza A virus
- C12N2760/16161—Methods of inactivation or attenuation
- C12N2760/16163—Methods of inactivation or attenuation by chemical treatment
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Dentistry (AREA)
- Plant Pathology (AREA)
- Agronomy & Crop Science (AREA)
- Environmental Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pest Control & Pesticides (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Virology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Immunology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Polymerization Catalysts (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US39511710P | 2010-05-06 | 2010-05-06 | |
| US61/395,117 | 2010-05-06 | ||
| PCT/IB2011/001394 WO2011138682A2 (en) | 2010-05-06 | 2011-05-06 | Organic peroxide compounds for microorganism inactivation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2796213A1 true CA2796213A1 (en) | 2011-11-10 |
Family
ID=44532956
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2796213A Abandoned CA2796213A1 (en) | 2010-05-06 | 2011-05-06 | Organic peroxide compounds for microorganism inactivation |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US9426989B2 (enExample) |
| EP (1) | EP2566323A2 (enExample) |
| JP (1) | JP6072677B2 (enExample) |
| KR (1) | KR20130079398A (enExample) |
| CN (1) | CN102946727B (enExample) |
| AU (1) | AU2011249487C1 (enExample) |
| BR (1) | BR112012028146A2 (enExample) |
| CA (1) | CA2796213A1 (enExample) |
| EA (1) | EA201291179A1 (enExample) |
| MX (1) | MX343948B (enExample) |
| WO (1) | WO2011138682A2 (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110804641A (zh) * | 2019-09-04 | 2020-02-18 | 中国农业科学院兰州兽医研究所 | 一种比较分析不同牛支原体菌株毒力的方法 |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8883848B2 (en) | 2011-07-14 | 2014-11-11 | Ecolab Usa Inc. | Enhanced microbial peracid compositions and methods of use at reduced temperatures in aseptic cleaning |
| US8906963B2 (en) | 2011-07-14 | 2014-12-09 | Ecolab Usa Inc | Deodorization of peracids |
| GB2495341B (en) | 2011-11-11 | 2013-09-18 | Novartis Ag | Fermentation methods and their products |
| ITUA20162517A1 (it) * | 2016-04-12 | 2017-10-12 | Andrea Fantozzi | Composizione per la conservazione/fissazione di materiale biologico |
| CA3080656A1 (en) | 2017-10-30 | 2019-05-09 | Baxalta GmbH | Environmentally compatible detergents for inactivation of lipid-enveloped viruses |
| AU2020380604A1 (en) | 2019-11-07 | 2022-06-09 | Seqirus UK Limited | Compositions and methods for producing a viral vaccine with reduced particle size |
Family Cites Families (44)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL288026A (enExample) * | 1963-01-16 | |||
| US3560395A (en) * | 1968-09-12 | 1971-02-02 | Pennwalt Corp | Aqueous ketone peroxide-hydrogen peroxide composition |
| US4060644A (en) * | 1976-02-09 | 1977-11-29 | Interox Chemicals Limited | Bleaching |
| DE2933498A1 (de) | 1979-08-18 | 1981-04-09 | Dr.rer.nat. Hans-Dieter 4234 Alpen Deppe | Chemothermisches desinfektions- und sterilisationsverfahren |
| PH25669A (en) * | 1985-12-19 | 1991-09-04 | Padmini Sampathkumar | Anaerobe-selective antibacterial compositions, methods |
| EP0461700A1 (en) | 1990-06-12 | 1991-12-18 | Akzo Nobel N.V. | Aqueous disinfectant compositions, and concentrates for preparing the same |
| US5437868A (en) * | 1991-07-23 | 1995-08-01 | Ecolab Inc. | Peroxyacid antimicrobial composition |
| GB9222561D0 (en) * | 1992-10-27 | 1992-12-09 | Ici Plc | Macromolecular degradation |
| US5824536A (en) * | 1994-08-23 | 1998-10-20 | St. Jude Children's Research Hospital | Influenza virus replicated in mammalian cell culture and vaccine production |
| FR2738127B1 (fr) | 1995-08-30 | 1998-03-27 | Oreal | Applicateur de mascara |
| DE19612966B4 (de) | 1996-04-01 | 2009-12-10 | Novartis Vaccines And Diagnostics Gmbh & Co. Kg | MDCK-Zellen und Verfahren zur Vermehrung von Influenzaviren |
| GB9612035D0 (en) * | 1996-06-08 | 1996-08-07 | Oilfield Chemical Additives Li | Method of inhibiting reservoir souring by bacteria |
| DE19817743A1 (de) * | 1998-04-21 | 1999-10-28 | Binker Materialschutz Gmbh | Materialschutzmittel |
| AU758625B2 (en) | 1998-08-20 | 2003-03-27 | Ecolab Inc. | The treatment of meat products |
| NZ517903A (en) | 1999-09-24 | 2003-10-31 | Smithkline Beecham Biolog S | One dose intranasal influenza virus vaccine with split influenza viral antigens |
| DE60142506D1 (de) | 2000-03-03 | 2010-08-19 | Chemo Sero Therapeut Res Inst | In serumfreier kultur verwendbare zelle, kultursuspension und verfahren zur virusproduktion als impfstoff unter verwendung der zelle |
| FR2808803B1 (fr) | 2000-05-11 | 2004-12-10 | Agronomique Inst Nat Rech | Cellules es modifiees et gene specifique de cellules es |
| GB0024089D0 (en) | 2000-10-02 | 2000-11-15 | Smithkline Beecham Biolog | Novel compounds |
| US20020107288A1 (en) * | 2000-12-08 | 2002-08-08 | Singh Waheguru Pal | Methods of sterilizing with dipercarboxylic acids |
| US7316824B2 (en) * | 2000-12-15 | 2008-01-08 | Ecolab Inc. | Method and composition for washing poultry during processing |
| US20040096463A1 (en) | 2001-02-23 | 2004-05-20 | Nathalie Garcon | Novel vaccine |
| CA2438942A1 (en) | 2001-02-23 | 2002-09-26 | Glaxosmithkline Biologicals S.A. | Influenza vaccine formulations for intradermal delivery |
| TWI228420B (en) | 2001-05-30 | 2005-03-01 | Smithkline Beecham Pharma Gmbh | Novel vaccine composition |
| US20030012804A1 (en) * | 2001-06-22 | 2003-01-16 | Aquacide And Use | Aquacide and use |
| EP1420065A4 (en) * | 2001-08-02 | 2005-03-09 | Anges Mg Inc | PROCESS FOR PRODUCING INACTIVE VIRAL ENVELOPES |
| DE10144903A1 (de) | 2001-09-12 | 2003-03-27 | Chiron Behring Gmbh & Co | Vermehrung von Viren in Zellkultur |
| DE10144906B4 (de) | 2001-09-12 | 2013-11-28 | Novartis Vaccines And Diagnostics Gmbh | Verfahren zur großtechnischen Herstellung von Impfstoffen |
| FR2832423B1 (fr) | 2001-11-22 | 2004-10-08 | Vivalis | Systeme d'expression de proteines exogenes dans un systeme aviaire |
| CN1194984C (zh) * | 2002-02-04 | 2005-03-30 | 中国农业科学院植物保护研究所 | 一种抗生素及其制备方法和应用 |
| FR2836924B1 (fr) | 2002-03-08 | 2005-01-14 | Vivalis | Lignees de cellules aviaires utiles pour la production de substances d'interet |
| JP4299514B2 (ja) * | 2002-08-29 | 2009-07-22 | 長谷川香料株式会社 | 抗菌抗カビ剤 |
| DE10306018A1 (de) * | 2003-02-13 | 2004-09-09 | Siemens Ag | Analyse- und Diagnostikinstrument |
| PT1637168E (pt) | 2003-04-16 | 2009-04-20 | Neochemical Desarrollos Avanza | Uso de um peróxido de dialquil cetona como agente biocida: esterilizante, anti-séptico, desinfectante e antiparasitário |
| EP1528101A1 (en) | 2003-11-03 | 2005-05-04 | ProBioGen AG | Immortalized avian cell lines for virus production |
| WO2005113756A1 (en) | 2004-05-14 | 2005-12-01 | Glaxosmithkline Biologicals S.A. | Method |
| NZ551640A (en) | 2004-05-20 | 2010-05-28 | Id Biomedical Corp | Process for the production of an influenza vaccine |
| CN101189326B (zh) | 2004-12-23 | 2013-06-12 | 米迪缪尼有限公司 | 用于病毒增殖的非致瘤性mdck细胞系 |
| GB0505909D0 (en) * | 2005-03-23 | 2005-04-27 | Univ Leeds | Formulations |
| FR2884255B1 (fr) | 2005-04-11 | 2010-11-05 | Vivalis | Utilisation de lignees de cellules souches aviaires ebx pour la production de vaccin contre la grippe |
| ES2423663T3 (es) * | 2005-08-08 | 2013-09-23 | Oregon Health And Science University | Inactivación de patógenos con peróxido de hidrógeno para la producción de vacunas |
| WO2007042175A1 (en) | 2005-10-07 | 2007-04-19 | Dsm Ip Assets B.V. | Peroxide decomposition catalyst |
| CN101365480B (zh) * | 2005-11-01 | 2014-11-05 | 诺华疫苗和诊断有限两合公司 | 经由β-丙内酯处理的残留细胞DNA水平降低的细胞衍生病毒疫苗 |
| ES2286949B1 (es) | 2006-05-26 | 2008-11-01 | Braulio Peña Rodriguez | Uso de combinaciones de peroxido de metil etil cetona por pulverizacion. |
| PL2121011T3 (pl) | 2006-12-06 | 2014-10-31 | Novartis Ag | Szczepionki zawierające antygeny czterech szczepów wirusa grypy |
-
2011
- 2011-05-06 EP EP11733909A patent/EP2566323A2/en not_active Withdrawn
- 2011-05-06 US US13/696,595 patent/US9426989B2/en not_active Expired - Fee Related
- 2011-05-06 AU AU2011249487A patent/AU2011249487C1/en not_active Ceased
- 2011-05-06 CN CN201180022567.3A patent/CN102946727B/zh not_active Expired - Fee Related
- 2011-05-06 WO PCT/IB2011/001394 patent/WO2011138682A2/en not_active Ceased
- 2011-05-06 CA CA2796213A patent/CA2796213A1/en not_active Abandoned
- 2011-05-06 EA EA201291179A patent/EA201291179A1/ru unknown
- 2011-05-06 MX MX2012012335A patent/MX343948B/es active IP Right Grant
- 2011-05-06 JP JP2013508577A patent/JP6072677B2/ja not_active Expired - Fee Related
- 2011-05-06 BR BR112012028146A patent/BR112012028146A2/pt not_active IP Right Cessation
- 2011-05-06 KR KR1020127030049A patent/KR20130079398A/ko not_active Withdrawn
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110804641A (zh) * | 2019-09-04 | 2020-02-18 | 中国农业科学院兰州兽医研究所 | 一种比较分析不同牛支原体菌株毒力的方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| EP2566323A2 (en) | 2013-03-13 |
| US20130149194A1 (en) | 2013-06-13 |
| AU2011249487C1 (en) | 2015-05-14 |
| AU2011249487B2 (en) | 2014-10-02 |
| JP2013528586A (ja) | 2013-07-11 |
| JP6072677B2 (ja) | 2017-02-01 |
| CN102946727A (zh) | 2013-02-27 |
| BR112012028146A2 (pt) | 2015-09-15 |
| WO2011138682A2 (en) | 2011-11-10 |
| MX2012012335A (es) | 2012-11-21 |
| CN102946727B (zh) | 2015-08-19 |
| US9426989B2 (en) | 2016-08-30 |
| WO2011138682A3 (en) | 2012-03-15 |
| AU2011249487A1 (en) | 2012-09-27 |
| MX343948B (es) | 2016-11-30 |
| EA201291179A1 (ru) | 2013-04-30 |
| KR20130079398A (ko) | 2013-07-10 |
| WO2011138682A8 (en) | 2012-07-19 |
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