CA2789446A1 - Methods for identifying and isolating cells expressing a polypeptide - Google Patents
Methods for identifying and isolating cells expressing a polypeptide Download PDFInfo
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- CA2789446A1 CA2789446A1 CA2789446A CA2789446A CA2789446A1 CA 2789446 A1 CA2789446 A1 CA 2789446A1 CA 2789446 A CA2789446 A CA 2789446A CA 2789446 A CA2789446 A CA 2789446A CA 2789446 A1 CA2789446 A1 CA 2789446A1
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Classifications
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- C07K—PEPTIDES
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- C07—ORGANIC CHEMISTRY
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- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
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- C07—ORGANIC CHEMISTRY
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- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
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- C07K16/2863—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
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- C—CHEMISTRY; METALLURGY
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- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
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- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
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- C07K2319/60—Fusion polypeptide containing spectroscopic/fluorescent detection, e.g. green fluorescent protein [GFP]
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| US61/304,251 | 2010-02-12 | ||
| US201161437889P | 2011-01-31 | 2011-01-31 | |
| US61/437,889 | 2011-01-31 | ||
| PCT/US2011/024554 WO2011100566A2 (en) | 2010-02-12 | 2011-02-11 | Methods for identifying and isolating cells expressing a polypeptide |
Publications (1)
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| CA2789446A1 true CA2789446A1 (en) | 2011-08-18 |
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| NZ (1) | NZ601743A (enExample) |
| SG (2) | SG10201503736XA (enExample) |
| WO (1) | WO2011100566A2 (enExample) |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US9228020B2 (en) | 2006-09-29 | 2016-01-05 | Oncomed Pharmaceuticals, Inc. | Compositions and methods for diagnosing and treating cancer |
| US9376488B2 (en) | 2011-09-23 | 2016-06-28 | Oncomed Pharmaceuticals, Inc. | VEGF binding antibodies |
| US9480744B2 (en) | 2010-09-10 | 2016-11-01 | Oncomed Pharmaceuticals, Inc. | Methods for treating melanoma |
| US9511139B2 (en) | 2009-10-16 | 2016-12-06 | Oncomed Pharmaceuticals, Inc. | Therapeutic combination and methods of treatment with a DLL4 antagonist and an anti-hypertensive agent |
| US9599620B2 (en) | 2012-10-31 | 2017-03-21 | Oncomed Pharmaceuticals, Inc. | Methods and monitoring of treatment with a DLL4 antagonist |
| US11046760B2 (en) | 2014-10-31 | 2021-06-29 | Oncomed Pharmaceuticals, Inc. | Combination therapy for treatment of disease |
| US11339213B2 (en) | 2015-09-23 | 2022-05-24 | Mereo Biopharma 5, Inc. | Methods and compositions for treatment of cancer |
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| PL2032166T3 (pl) | 2006-06-13 | 2013-09-30 | Oncomed Pharm Inc | Kompozycje i sposoby diagnozowania i leczenia nowotworów |
| JP5618544B2 (ja) | 2007-01-24 | 2014-11-05 | オンコメッドファーマシューティカルズ インコーポレイテッド | 癌の診断および処置のための組成物および方法 |
| US9249423B2 (en) | 2007-02-02 | 2016-02-02 | Yale University | Method of de-differentiating and re-differentiating somatic cells using RNA |
| US10155038B2 (en) | 2007-02-02 | 2018-12-18 | Yale University | Cells prepared by transient transfection and methods of use thereof |
| US8859229B2 (en) * | 2007-02-02 | 2014-10-14 | Yale University | Transient transfection with RNA |
| CN102316897B (zh) | 2008-07-08 | 2014-11-05 | 昂考梅德药品有限公司 | Notch结合剂和拮抗剂及其应用方法 |
| US9132189B2 (en) | 2008-07-08 | 2015-09-15 | Oncomed Pharmaceuticals, Inc. | Notch1 binding agents and methods of use thereof |
| US8551715B2 (en) | 2010-02-12 | 2013-10-08 | Oncomed Pharmaceuticals, Inc. | Methods for identifying and isolating cells expressing a polypeptide |
| US9365846B2 (en) | 2010-12-01 | 2016-06-14 | Merck Sharp & Dohme Corp. | Surface, anchored Fc-bait antibody display system |
| US10106598B2 (en) | 2010-12-01 | 2018-10-23 | Merck Sharp & Dohme Corp. | Surface, anchored Fc-bait antibody display system |
| CN106167526A (zh) | 2011-07-15 | 2016-11-30 | 昂考梅德药品有限公司 | Rspo结合剂和其应用 |
| WO2013184912A2 (en) | 2012-06-06 | 2013-12-12 | Oncomed Pharmaceuticals, Inc. | Binding agents that modulate the hippo pathway and uses thereof |
| CA2878868A1 (en) | 2012-07-13 | 2014-01-16 | Austin L. Gurney | Rspo3 binding agents and uses thereof |
| PL3489261T3 (pl) | 2012-08-24 | 2021-08-16 | The Regents Of The University Of California | Przeciwciała i szczepionki do stosowania w leczeniu nowotworów z ekspresją ROR1 i w hamowaniu przerzutu |
| WO2014062659A2 (en) * | 2012-10-15 | 2014-04-24 | Oncomed Pharmaceuticals, Inc. | Methods of treating ocular diseases |
| US8921055B2 (en) * | 2012-10-30 | 2014-12-30 | Berkeley Lights, Inc. | Detecting cells secreting a protein of interest |
| US20150320799A1 (en) | 2012-12-20 | 2015-11-12 | Purdue Research Foundation | Chimeric antigen receptor-expressing t cells as anti-cancer therapeutics |
| AU2014249148B2 (en) * | 2013-03-11 | 2020-04-02 | Regeneron Pharmaceuticals, Inc. | Transgenic mice expressing chimeric major histocompatibility complex (mhc) class ii molecules |
| GB201405845D0 (en) | 2014-04-01 | 2014-05-14 | Ucl Business Plc | Signalling system |
| GB201407852D0 (en) | 2014-05-02 | 2014-06-18 | Iontas Ltd | Preparation of libraries od protein variants expressed in eukaryotic cells and use for selecting binding molecules |
| GB201415347D0 (en) | 2014-08-29 | 2014-10-15 | Ucl Business Plc | Signalling system |
| AU2015343048A1 (en) * | 2014-11-06 | 2017-05-18 | Children's Research Institute, Children's National Medical Center | Immunotherapeutics for cancer and autoimmune diseases |
| KR102558502B1 (ko) | 2014-12-05 | 2023-07-20 | 시티 오브 호프 | Ｃｓ1 표적화된 키메라 항원 수용체-변형된 ｔ 세포 |
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| US9376497B2 (en) | 2006-09-29 | 2016-06-28 | Oncomed Pharmaceuticals, Inc. | Compositions and methods for diagnosing and treating cancer |
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| US10870693B2 (en) | 2009-10-16 | 2020-12-22 | Oncomed Pharmaceuticals, Inc. | Therapeutic combination and methods of treatment with a DLL4 antagonist and an anti-hypertensive agent |
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| US9879084B2 (en) | 2011-09-23 | 2018-01-30 | Oncomed Pharmaceuticals, Inc. | Modified immunoglobulin molecules that specifically bind human VEGF and DLL4 |
| US9574009B2 (en) | 2011-09-23 | 2017-02-21 | Oncomed Pharmaceuticals, Inc. | Polynucleotides encoding VEGF/DLL4 binding agents |
| US9376488B2 (en) | 2011-09-23 | 2016-06-28 | Oncomed Pharmaceuticals, Inc. | VEGF binding antibodies |
| US11512128B2 (en) | 2011-09-23 | 2022-11-29 | Mereo Biopharma 5, Inc. | VEGF/DLL4 binding agents and uses thereof |
| US9599620B2 (en) | 2012-10-31 | 2017-03-21 | Oncomed Pharmaceuticals, Inc. | Methods and monitoring of treatment with a DLL4 antagonist |
| US11046760B2 (en) | 2014-10-31 | 2021-06-29 | Oncomed Pharmaceuticals, Inc. | Combination therapy for treatment of disease |
| US11339213B2 (en) | 2015-09-23 | 2022-05-24 | Mereo Biopharma 5, Inc. | Methods and compositions for treatment of cancer |
Also Published As
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| JP6034696B2 (ja) | 2016-11-30 |
| IL221349A0 (en) | 2012-10-31 |
| US20140005077A1 (en) | 2014-01-02 |
| CN102844442A (zh) | 2012-12-26 |
| US8945878B2 (en) | 2015-02-03 |
| US20150315565A1 (en) | 2015-11-05 |
| WO2011100566A3 (en) | 2011-10-06 |
| SG10201503736XA (en) | 2015-06-29 |
| SG183196A1 (en) | 2012-09-27 |
| US8551715B2 (en) | 2013-10-08 |
| EP2534257A2 (en) | 2012-12-19 |
| JP2013519379A (ja) | 2013-05-30 |
| US20140005076A1 (en) | 2014-01-02 |
| US20110287979A1 (en) | 2011-11-24 |
| NZ601743A (en) | 2014-11-28 |
| KR20120117931A (ko) | 2012-10-24 |
| US9023621B2 (en) | 2015-05-05 |
| US20170002054A1 (en) | 2017-01-05 |
| AU2011215685A1 (en) | 2012-08-30 |
| MX2012009175A (es) | 2012-12-17 |
| EP2534257B1 (en) | 2017-09-27 |
| AU2011215685B2 (en) | 2015-08-20 |
| EP2534257A4 (en) | 2013-11-20 |
| WO2011100566A2 (en) | 2011-08-18 |
| US9873726B2 (en) | 2018-01-23 |
| CN102844442B (zh) | 2016-09-07 |
| JP2017014220A (ja) | 2017-01-19 |
| US9422546B2 (en) | 2016-08-23 |
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