CA2789411A1 - Diagnosis of systemic lupus erythematosus (sle) - Google Patents

Diagnosis of systemic lupus erythematosus (sle) Download PDF

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Publication number
CA2789411A1
CA2789411A1 CA2789411A CA2789411A CA2789411A1 CA 2789411 A1 CA2789411 A1 CA 2789411A1 CA 2789411 A CA2789411 A CA 2789411A CA 2789411 A CA2789411 A CA 2789411A CA 2789411 A1 CA2789411 A1 CA 2789411A1
Authority
CA
Canada
Prior art keywords
antigens
reactivity
sample
sle
antigen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2789411A
Other languages
English (en)
French (fr)
Inventor
Irun R. Cohen
Eytan Domany
Noam Shental
Ittai Fattal
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tel HaShomer Medical Research Infrastructure and Services Ltd
Yeda Research and Development Co Ltd
Original Assignee
Tel HaShomer Medical Research Infrastructure and Services Ltd
Yeda Research and Development Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tel HaShomer Medical Research Infrastructure and Services Ltd, Yeda Research and Development Co Ltd filed Critical Tel HaShomer Medical Research Infrastructure and Services Ltd
Publication of CA2789411A1 publication Critical patent/CA2789411A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/564—Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/10—Musculoskeletal or connective tissue disorders
    • G01N2800/101—Diffuse connective tissue disease, e.g. Sjögren, Wegener's granulomatosis
    • G01N2800/104—Lupus erythematosus [SLE]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Rehabilitation Therapy (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Rheumatology (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
CA2789411A 2010-02-12 2011-02-13 Diagnosis of systemic lupus erythematosus (sle) Abandoned CA2789411A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US30369110P 2010-02-12 2010-02-12
US61/303,691 2010-02-12
PCT/IL2011/000153 WO2011099012A1 (en) 2010-02-12 2011-02-13 Diagnosis of systemic lupus erythematosus (sle)

Publications (1)

Publication Number Publication Date
CA2789411A1 true CA2789411A1 (en) 2011-08-18

Family

ID=43971423

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2789411A Abandoned CA2789411A1 (en) 2010-02-12 2011-02-13 Diagnosis of systemic lupus erythematosus (sle)

Country Status (8)

Country Link
US (2) US20130035254A1 (enExample)
EP (1) EP2534487B1 (enExample)
JP (1) JP5894539B2 (enExample)
CN (1) CN102762983B (enExample)
AU (1) AU2011213923A1 (enExample)
CA (1) CA2789411A1 (enExample)
ES (1) ES2560809T3 (enExample)
WO (1) WO2011099012A1 (enExample)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8652999B1 (en) 2012-07-24 2014-02-18 Dow Agrosciences, Llc. Herbicidal compositions comprising 4-amino-3-chloro-5-fluoro-6-(4-chloro-2-fluoro-3-methoxyphenyl)pyridine-2-carboxylic acid or a derivative thereof and a sulfonylaminocarbonyltriazolinone
EP2698636A1 (en) * 2012-08-13 2014-02-19 Fundació Institut d'Investigació Biomèdica de Bellvitge Methods and reagents for prevention and/or treatment of transplant rejection
CA2888880A1 (en) * 2012-12-16 2014-06-19 Yeda Research And Development Co. Ltd. Diagnosis of autoimmune diseases using a specific antibody profile
CN104007266B (zh) * 2013-02-27 2016-04-20 中国医学科学院基础医学研究所 含有6-n-甲基赖氨酸残基的抗原在制备辅助诊断系统性红斑狼疮试剂中的应用
CN105229470B (zh) * 2013-03-15 2018-11-27 艾克斯肯诊断股份有限公司 用于治疗和诊断系统性红斑狼疮的方法
EP3090064B1 (en) * 2013-12-31 2019-11-13 Yeda Research and Development Co. Ltd. Diagnosis of systemic lupus erythematosus using oligonucleotides antigens
US20160320384A1 (en) 2013-12-31 2016-11-03 Yeda Research And Development Co. Ltd. Methods for assaying immunological competence
EP2933639A1 (en) * 2014-04-16 2015-10-21 Deutsches Krebsforschungszentrum Stiftung des Öffentlichen Rechts S100p and Hyaluronic acid as biomarkers for metastatic breast cancer
EP3134733B1 (en) * 2014-04-25 2020-10-14 The Brigham and Women's Hospital, Inc. Assay and method for treating subjects with immune-mediated diseases
BR112017002575B1 (pt) * 2014-08-08 2023-11-07 Allegheny Singer Research Institute Método para diagnosticar especificamente lúpus sistêmico eritematoso em um indivíduo
WO2016139659A1 (en) * 2015-03-01 2016-09-09 Immunarray Ltd. Diagnosis of systemic lupus erythematosus using protein, peptide and oligonucleotide antigens
WO2017223116A2 (en) 2016-06-20 2017-12-28 Healthtell Inc. Methods for differential diagnosis of autoimmune diseases
CN109790203A (zh) 2016-06-20 2019-05-21 健康之语公司 自身免疫疾病的诊断和治疗方法
CN110168370A (zh) 2016-11-11 2019-08-23 健康之语公司 用于鉴定候选生物标志物的方法
JP7271421B2 (ja) * 2016-12-16 2023-05-11 メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング ループス腎炎の重篤度と進行をモニタリングするために尿中に検出されるガレクチン３結合タンパク質を使用する方法
CN107151672B (zh) * 2017-05-11 2021-05-28 成都医学院 一种重组质粒及其用途
US11480568B2 (en) 2017-09-28 2022-10-25 Yeda Research And Development Co. Ltd. Diagnosis of autoimmune diseases
BR102018075339A2 (pt) * 2018-12-06 2021-11-16 Fundação Oswaldo Cruz Proteína recombinante, sequência de dna sintético, vetor de expressão, célula hospedeira, composição, kit para diagnóstico de rubéola, uso de pelo menos uma proteína recombinante, e, métodos para produzir uma proteína recombinante e para diagnóstico de rubéola

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5552391A (en) * 1990-01-16 1996-09-03 La Jolla Pharmaceutical Company Chemically-defined non-polymeric valency platform molecules and conjugates thereof
WO2001082960A1 (en) * 2000-04-28 2001-11-08 The Board Of Trustees Of The Leland Stanford Junior University Inhibition of polyclonal b cell activation and immunoglobulin class switching to pathogenic autoantibodies by blocking cd1-mediated interactions
IL137460A0 (en) 2000-07-24 2001-07-24 Yeda Res & Dev Identifying antigen clusters for monitoring a global state of an immune system
WO2002042775A2 (en) * 2000-11-27 2002-05-30 Genevention L.L.C. Clinically intelligent diagnostic devices and methods
ES2239532B1 (es) * 2004-02-06 2006-11-01 Proyecto De Biomedicina Cima S.L. Metodo para evaluar el riesgo y la predisposicion a desarrollar una patologia relacionada con la presencia de autoanticuerpos frente a epcr.
US20050260770A1 (en) 2004-04-01 2005-11-24 Cohen Irun R Antigen array and diagnostic uses thereof
US20070141627A1 (en) * 2005-10-19 2007-06-21 Behrens Timothy W Systemic Lupus Erythematosus
JP2010510528A (ja) * 2006-11-22 2010-04-02 ライフ テクノロジーズ コーポレーション 自己免疫疾患のバイオマーカー
CN101329341B (zh) * 2008-07-09 2012-06-27 北京美康生物技术研究中心 检测自身免疫疾病相关抗核抗体谱的试剂盒及其制备方法
CN102803965A (zh) 2009-05-05 2012-11-28 耶达研究与发展有限公司 用于识别个人心血管疾病的发生的装置和方法

Also Published As

Publication number Publication date
WO2011099012A1 (en) 2011-08-18
JP2013519875A (ja) 2013-05-30
EP2534487A1 (en) 2012-12-19
ES2560809T3 (es) 2016-02-22
US20130035254A1 (en) 2013-02-07
JP5894539B2 (ja) 2016-03-30
CN102762983B (zh) 2016-01-20
AU2011213923A1 (en) 2012-08-30
US20140342939A1 (en) 2014-11-20
EP2534487B1 (en) 2015-11-04
CN102762983A (zh) 2012-10-31

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Legal Events

Date Code Title Description
EEER Examination request

Effective date: 20160111

FZDE Discontinued

Effective date: 20190213