CA2786341A1 - Methods and compositions for altering temperature sensing in eukaryotic organisms - Google Patents
Methods and compositions for altering temperature sensing in eukaryotic organisms Download PDFInfo
- Publication number
- CA2786341A1 CA2786341A1 CA2786341A CA2786341A CA2786341A1 CA 2786341 A1 CA2786341 A1 CA 2786341A1 CA 2786341 A CA2786341 A CA 2786341A CA 2786341 A CA2786341 A CA 2786341A CA 2786341 A1 CA2786341 A1 CA 2786341A1
- Authority
- CA
- Canada
- Prior art keywords
- altering
- nucleic acid
- plant
- nucleosome
- inhibiting
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 238000000034 method Methods 0.000 title claims 47
- 239000000203 mixture Substances 0.000 title claims 3
- 102100023919 Histone H2A.Z Human genes 0.000 claims abstract 48
- 101001084710 Drosophila melanogaster Histone H2A.v Proteins 0.000 claims abstract 47
- 101000905054 Homo sapiens Histone H2A.Z Proteins 0.000 claims abstract 47
- 108010047956 Nucleosomes Proteins 0.000 claims abstract 17
- 210000001623 nucleosome Anatomy 0.000 claims abstract 17
- 150000007523 nucleic acids Chemical group 0.000 claims 19
- 241000196324 Embryophyta Species 0.000 claims 16
- 230000002401 inhibitory effect Effects 0.000 claims 16
- 108091028043 Nucleic acid sequence Proteins 0.000 claims 15
- 230000003247 decreasing effect Effects 0.000 claims 13
- 230000021736 acetylation Effects 0.000 claims 10
- 238000006640 acetylation reaction Methods 0.000 claims 10
- 102000003964 Histone deacetylase Human genes 0.000 claims 9
- 108090000353 Histone deacetylase Proteins 0.000 claims 9
- 102000004190 Enzymes Human genes 0.000 claims 6
- 108090000790 Enzymes Proteins 0.000 claims 6
- 108090000623 proteins and genes Proteins 0.000 claims 6
- 108020004705 Codon Proteins 0.000 claims 5
- 230000000694 effects Effects 0.000 claims 5
- 230000004481 post-translational protein modification Effects 0.000 claims 5
- 244000038559 crop plants Species 0.000 claims 4
- 102000003893 Histone acetyltransferases Human genes 0.000 claims 3
- 108090000246 Histone acetyltransferases Proteins 0.000 claims 3
- 240000007594 Oryza sativa Species 0.000 claims 3
- 235000007164 Oryza sativa Nutrition 0.000 claims 3
- 241000209140 Triticum Species 0.000 claims 3
- 235000021307 Triticum Nutrition 0.000 claims 3
- 235000013339 cereals Nutrition 0.000 claims 3
- 235000018977 lysine Nutrition 0.000 claims 3
- 235000009566 rice Nutrition 0.000 claims 3
- 230000017260 vegetative to reproductive phase transition of meristem Effects 0.000 claims 3
- 241000219198 Brassica Species 0.000 claims 2
- 235000011331 Brassica Nutrition 0.000 claims 2
- 244000068988 Glycine max Species 0.000 claims 2
- 235000010469 Glycine max Nutrition 0.000 claims 2
- 240000005979 Hordeum vulgare Species 0.000 claims 2
- 235000007340 Hordeum vulgare Nutrition 0.000 claims 2
- KDXKERNSBIXSRK-UHFFFAOYSA-N Lysine Natural products NCCCCC(N)C(O)=O KDXKERNSBIXSRK-UHFFFAOYSA-N 0.000 claims 2
- 239000004472 Lysine Substances 0.000 claims 2
- 240000000111 Saccharum officinarum Species 0.000 claims 2
- 235000007201 Saccharum officinarum Nutrition 0.000 claims 2
- 244000082988 Secale cereale Species 0.000 claims 2
- 235000007238 Secale cereale Nutrition 0.000 claims 2
- 240000006394 Sorghum bicolor Species 0.000 claims 2
- 235000011684 Sorghum saccharatum Nutrition 0.000 claims 2
- 240000008042 Zea mays Species 0.000 claims 2
- 235000005824 Zea mays ssp. parviglumis Nutrition 0.000 claims 2
- 235000002017 Zea mays subsp mays Nutrition 0.000 claims 2
- 235000005822 corn Nutrition 0.000 claims 2
- 241001233957 eudicotyledons Species 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- 108020004707 nucleic acids Proteins 0.000 claims 2
- 102000039446 nucleic acids Human genes 0.000 claims 2
- 239000002773 nucleotide Substances 0.000 claims 2
- 125000003729 nucleotide group Chemical group 0.000 claims 2
- 230000002028 premature Effects 0.000 claims 2
- 235000018102 proteins Nutrition 0.000 claims 2
- 102000004169 proteins and genes Human genes 0.000 claims 2
- 210000001519 tissue Anatomy 0.000 claims 2
- 102100031468 Actin-related protein 6 Human genes 0.000 claims 1
- 241000195493 Cryptophyta Species 0.000 claims 1
- 241000233866 Fungi Species 0.000 claims 1
- 102100031880 Helicase SRCAP Human genes 0.000 claims 1
- 101710090647 Histone H2A.Z Proteins 0.000 claims 1
- 101000923097 Homo sapiens Actin-related protein 6 Proteins 0.000 claims 1
- 101000964382 Homo sapiens DNA dC->dU-editing enzyme APOBEC-3D Proteins 0.000 claims 1
- 101000704158 Homo sapiens Helicase SRCAP Proteins 0.000 claims 1
- 238000012228 RNA interference-mediated gene silencing Methods 0.000 claims 1
- 240000004808 Saccharomyces cerevisiae Species 0.000 claims 1
- 241000251539 Vertebrata <Metazoa> Species 0.000 claims 1
- 125000002777 acetyl group Chemical group [H]C([H])([H])C(*)=O 0.000 claims 1
- 125000000539 amino acid group Chemical group 0.000 claims 1
- 230000006196 deacetylation Effects 0.000 claims 1
- 238000003381 deacetylation reaction Methods 0.000 claims 1
- 230000001419 dependent effect Effects 0.000 claims 1
- 230000003828 downregulation Effects 0.000 claims 1
- 230000009368 gene silencing by RNA Effects 0.000 claims 1
- 230000006195 histone acetylation Effects 0.000 claims 1
- 125000003588 lysine group Chemical class [H]N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])(N([H])[H])C(*)=O 0.000 claims 1
- 244000005700 microbiome Species 0.000 claims 1
- 230000008506 pathogenesis Effects 0.000 claims 1
- 230000001105 regulatory effect Effects 0.000 claims 1
- 230000003827 upregulation Effects 0.000 claims 1
- 241000206602 Eukaryota Species 0.000 abstract 1
- 230000004048 modification Effects 0.000 abstract 1
- 238000012986 modification Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8216—Methods for controlling, regulating or enhancing expression of transgenes in plant cells
- C12N15/8237—Externally regulated expression systems
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
- C12N15/8262—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield involving plant development
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
- C12N15/8262—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield involving plant development
- C12N15/827—Flower development or morphology, e.g. flowering promoting factor [FPF]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
- C12N15/8271—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
- C12N15/8271—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
- C12N15/8279—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance
Landscapes
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Cell Biology (AREA)
- Botany (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Physiology (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Radiation Pyrometers (AREA)
- Enzymes And Modification Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1000184.0 | 2010-01-07 | ||
| GBGB1000184.0A GB201000184D0 (en) | 2010-01-07 | 2010-01-07 | Methods and compositions for altering temperature sensing in eukaryotic organisms |
| PCT/GB2010/050956 WO2011083290A1 (en) | 2010-01-07 | 2010-06-08 | Methods and compositions for altering temperature sensing in eukaryotic organisms |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2786341A1 true CA2786341A1 (en) | 2011-07-14 |
Family
ID=41819024
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2786341A Abandoned CA2786341A1 (en) | 2010-01-07 | 2010-06-08 | Methods and compositions for altering temperature sensing in eukaryotic organisms |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20130239252A1 (https=) |
| EP (1) | EP2521734B1 (https=) |
| CN (1) | CN102781956B (https=) |
| AR (1) | AR079319A1 (https=) |
| AU (1) | AU2010340802B2 (https=) |
| BR (1) | BR112012016796A2 (https=) |
| CA (1) | CA2786341A1 (https=) |
| GB (1) | GB201000184D0 (https=) |
| IN (1) | IN2012DN06570A (https=) |
| MX (1) | MX2012007867A (https=) |
| WO (2) | WO2011083290A1 (https=) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105980395A (zh) | 2013-11-04 | 2016-09-28 | 美国陶氏益农公司 | 最优大豆座位 |
| UY35812A (es) | 2013-11-04 | 2015-05-29 | Dow Agrosciences Llc | ?loci de maíz óptimos?. |
| NZ746567A (en) | 2013-11-04 | 2019-09-27 | Dow Agrosciences Llc | Optimal soybean loci |
| NZ719494A (en) | 2013-11-04 | 2017-09-29 | Dow Agrosciences Llc | Optimal maize loci |
| CN104894142A (zh) * | 2015-06-11 | 2015-09-09 | 中国科学院西北高原生物研究所 | 调控花青素合成与代谢的小麦新基因TaMYB7D |
| EP3712271A1 (en) | 2019-03-18 | 2020-09-23 | Commissariat à l'Energie Atomique et aux Energies Alternatives | Altering thermoresponsive growth in plants via genome editing of phytochrome interacting factor 4 (pif4) regulatory elements |
| CN110938605B (zh) * | 2019-11-20 | 2021-05-04 | 中山大学附属第五医院 | 一种体外组装的HBV cccDNA核小体及其制备方法 |
| CN111153980B (zh) * | 2020-02-17 | 2022-03-15 | 南京农业大学 | 一种植物粒型相关蛋白OsSDSG及其编码基因与应用 |
| CN117965579B (zh) * | 2024-04-02 | 2024-06-07 | 中国科学院遗传与发育生物学研究所 | 麦属特异转座子h2a.1及其应用 |
| WO2025233441A1 (en) | 2024-05-08 | 2025-11-13 | Gmi - Gregor-Mendel-Institut Für Molekulare Pflanzenbiologie Gmbh | Modified h2a.z l2 region |
| CN120796341A (zh) * | 2025-06-25 | 2025-10-17 | 浙江大学 | 番茄组蛋白变体h2a.z在提高番茄低温抗性中的应用 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2316036A1 (en) * | 1999-08-27 | 2001-02-27 | Keqiang Wu | Repressing gene expression in plants |
| EP1313867A2 (en) * | 2000-08-24 | 2003-05-28 | The Scripps Research Institute | Stress-regulated genes of plants, transgenic plants containing same, and methods of use |
-
2010
- 2010-01-07 GB GBGB1000184.0A patent/GB201000184D0/en not_active Ceased
- 2010-06-08 WO PCT/GB2010/050956 patent/WO2011083290A1/en not_active Ceased
- 2010-06-08 EP EP10724120.0A patent/EP2521734B1/en not_active Not-in-force
- 2010-06-08 AU AU2010340802A patent/AU2010340802B2/en not_active Ceased
- 2010-06-08 MX MX2012007867A patent/MX2012007867A/es active IP Right Grant
- 2010-06-08 IN IN6570DEN2012 patent/IN2012DN06570A/en unknown
- 2010-06-08 BR BR112012016796A patent/BR112012016796A2/pt not_active IP Right Cessation
- 2010-06-08 CA CA2786341A patent/CA2786341A1/en not_active Abandoned
- 2010-06-08 CN CN201080060911.3A patent/CN102781956B/zh not_active Expired - Fee Related
- 2010-06-08 US US13/520,967 patent/US20130239252A1/en not_active Abandoned
- 2010-12-07 AR ARP100104519A patent/AR079319A1/es unknown
- 2010-12-17 WO PCT/GB2010/052144 patent/WO2011083298A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| AR079319A1 (es) | 2012-01-18 |
| EP2521734B1 (en) | 2016-09-14 |
| MX2012007867A (es) | 2012-08-03 |
| IN2012DN06570A (https=) | 2015-10-23 |
| GB201000184D0 (en) | 2010-02-24 |
| US20130239252A1 (en) | 2013-09-12 |
| EP2521734A1 (en) | 2012-11-14 |
| AU2010340802B2 (en) | 2014-03-13 |
| AU2010340802A1 (en) | 2012-06-21 |
| CN102781956B (zh) | 2015-09-16 |
| WO2011083298A1 (en) | 2011-07-14 |
| CN102781956A (zh) | 2012-11-14 |
| WO2011083290A1 (en) | 2011-07-14 |
| BR112012016796A2 (pt) | 2019-09-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request |
Effective date: 20140328 |
|
| FZDE | Discontinued |
Effective date: 20180608 |