CA2785249A1 - Pharmaceutical composition comprising vitamin d analogue and cosolvent-surfactant mixture - Google Patents

Pharmaceutical composition comprising vitamin d analogue and cosolvent-surfactant mixture Download PDF

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Publication number
CA2785249A1
CA2785249A1 CA2785249A CA2785249A CA2785249A1 CA 2785249 A1 CA2785249 A1 CA 2785249A1 CA 2785249 A CA2785249 A CA 2785249A CA 2785249 A CA2785249 A CA 2785249A CA 2785249 A1 CA2785249 A1 CA 2785249A1
Authority
CA
Canada
Prior art keywords
composition according
calcipotriol
composition
peg
vitamin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2785249A
Other languages
English (en)
French (fr)
Inventor
Karsten Petersson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Leo Pharma AS
Original Assignee
Leo Pharma AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Leo Pharma AS filed Critical Leo Pharma AS
Publication of CA2785249A1 publication Critical patent/CA2785249A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A61K31/405—Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/113—Multiple emulsions, e.g. oil-in-water-in-oil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/08—Antiseborrheics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CA2785249A 2009-12-22 2009-12-22 Pharmaceutical composition comprising vitamin d analogue and cosolvent-surfactant mixture Abandoned CA2785249A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/DK2009/000266 WO2011076206A1 (en) 2009-12-22 2009-12-22 Pharmaceutical composition comprising vitamin d analogue and cosolvent-surfactant mixture

Publications (1)

Publication Number Publication Date
CA2785249A1 true CA2785249A1 (en) 2011-06-30

Family

ID=44194970

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2785249A Abandoned CA2785249A1 (en) 2009-12-22 2009-12-22 Pharmaceutical composition comprising vitamin d analogue and cosolvent-surfactant mixture

Country Status (13)

Country Link
EP (1) EP2515912A4 (zh)
JP (1) JP5548275B2 (zh)
CN (1) CN102770143B (zh)
AU (1) AU2009357263B2 (zh)
BR (1) BR112012015447A2 (zh)
CA (1) CA2785249A1 (zh)
HK (1) HK1177695A1 (zh)
IL (1) IL220513A (zh)
MX (1) MX2012007227A (zh)
NZ (1) NZ601002A (zh)
RU (1) RU2500387C1 (zh)
WO (1) WO2011076206A1 (zh)
ZA (1) ZA201204619B (zh)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022040773A1 (en) * 2020-08-26 2022-03-03 Canadian Nano Pharmaceutical Technology Inc. Nano-emulsion based compositions, methods for their preparation and their use in delivery of active ingredients

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107643354B (zh) * 2016-07-22 2022-02-01 重庆华邦胜凯制药有限公司 卡泊三醇起始原料a及相关杂质的分离与测定方法
CN106265511A (zh) * 2016-08-22 2017-01-04 江苏知原药业有限公司 一种性能优异的卡泊三醇倍他米松自微乳制剂
CN106265485A (zh) * 2016-08-22 2017-01-04 江苏知原药业有限公司 一种稳定性改善的卡泊三醇组合物
CN106344589B (zh) * 2016-11-10 2019-11-26 江苏知原药业有限公司 一种稳定性改善的卡泊三醇倍他米松组合物
CN108904445A (zh) * 2018-08-06 2018-11-30 江苏知原药业有限公司 钙泊三醇纳米悬浮液
CN115350151B (zh) * 2022-09-29 2023-09-12 湖北欣泽霏药业有限公司 一种高稳定性阿法骨化醇液体口服制剂及其制备方法
CN116473985A (zh) * 2023-03-29 2023-07-25 暨南大学 一种多烯类抗真菌药物组合物及其应用

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE39706E1 (en) * 1993-01-15 2007-06-26 Leo Pharma A/S Crystalline form of a vitamin D analogue
JP3340310B2 (ja) * 1996-03-28 2002-11-05 株式会社資生堂 複合エマルジョンおよびその製造方法
US6432422B1 (en) * 1997-12-09 2002-08-13 Chugai Seiyaku Kabushiki Kaisha Creams containing vitamin D3 derivatives
CA2312060A1 (en) * 1997-12-09 1999-06-17 Chugai Seiyaku Kabushiki Kaisha Lotions containing vitamin d3 derivatives
US5990100A (en) * 1998-03-24 1999-11-23 Panda Pharmaceuticals, L.L.C. Composition and method for treatment of psoriasis
US8263580B2 (en) * 1998-09-11 2012-09-11 Stiefel Research Australia Pty Ltd Vitamin formulation
PT1178960E (pt) * 1999-04-23 2004-03-31 Leo Pharma As Analogos da vitamina d e sua utilizacao farmaceutica
JP2001025359A (ja) * 1999-07-15 2001-01-30 Mitsubishi-Kagaku Foods Corp Ｏ／ｗ／ｏ型エマルジョン組成物およびその製造方法
EP1901709A2 (en) * 2005-06-10 2008-03-26 Galderma S.A. Controlled release of a drug through skin on the basis of a topical composition comprising a drug, a film-forming silicone and at least one volatile solvent
WO2006138056A1 (en) * 2005-06-15 2006-12-28 Apollo Pharmaceutical, Inc. Pharmaceutical composition comprising a mahonia aquifolium extract for the treatment of psoriasis
FR2893847B1 (fr) * 2005-11-30 2010-10-29 Galderma Sa Composition sous forme de spray comprenant un derive de vitamine d et une phase huileuse
JP4913487B2 (ja) * 2006-07-07 2012-04-11 ポーラ化成工業株式会社 使用感に特徴のある化粧料
FR2909284B1 (fr) * 2006-11-30 2012-09-21 Galderma Sa Nouvelles compositions sous forme d'onguent sans vaseline comprenant un derive de vitamine d et eventuellement un anti-inflammatoire steroidien
FR2911781B1 (fr) * 2007-01-26 2009-03-20 Fabre Pierre Dermo Cosmetique Emulsion dermatologique et procede de preparation
US10265265B2 (en) * 2007-03-15 2019-04-23 Drug Delivery Solutions Limited Topical composition
EP1970049A1 (en) * 2007-03-15 2008-09-17 Drug Delivery Solutions Limited Polyaphron topical composition with vitamin D and corticosteroid

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022040773A1 (en) * 2020-08-26 2022-03-03 Canadian Nano Pharmaceutical Technology Inc. Nano-emulsion based compositions, methods for their preparation and their use in delivery of active ingredients

Also Published As

Publication number Publication date
CN102770143B (zh) 2014-11-05
ZA201204619B (en) 2013-09-25
AU2009357263A1 (en) 2012-07-19
CN102770143A (zh) 2012-11-07
NZ601002A (en) 2014-09-26
HK1177695A1 (zh) 2013-08-30
IL220513A (en) 2016-05-31
RU2500387C1 (ru) 2013-12-10
AU2009357263B2 (en) 2015-04-09
EP2515912A1 (en) 2012-10-31
WO2011076206A1 (en) 2011-06-30
IL220513A0 (en) 2012-08-30
EP2515912A4 (en) 2013-12-25
JP2013515017A (ja) 2013-05-02
JP5548275B2 (ja) 2014-07-16
BR112012015447A2 (pt) 2016-03-15
MX2012007227A (es) 2012-07-30

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Legal Events

Date Code Title Description
EEER Examination request

Effective date: 20140617

FZDE Discontinued

Effective date: 20180529