CA2784351C - Integrated hinged cartridge housings for sample analysis - Google Patents
Integrated hinged cartridge housings for sample analysis Download PDFInfo
- Publication number
- CA2784351C CA2784351C CA2784351A CA2784351A CA2784351C CA 2784351 C CA2784351 C CA 2784351C CA 2784351 A CA2784351 A CA 2784351A CA 2784351 A CA2784351 A CA 2784351A CA 2784351 C CA2784351 C CA 2784351C
- Authority
- CA
- Canada
- Prior art keywords
- housing
- cartridge
- zone
- conduit
- sensor
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
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- WKBPZYKAUNRMKP-UHFFFAOYSA-N 1-[2-(2,4-dichlorophenyl)pentyl]1,2,4-triazole Chemical compound C=1C=C(Cl)C=C(Cl)C=1C(CCC)CN1C=NC=N1 WKBPZYKAUNRMKP-UHFFFAOYSA-N 0.000 claims description 4
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- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 description 2
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 2
- 239000004743 Polypropylene Substances 0.000 description 2
- XUIMIQQOPSSXEZ-UHFFFAOYSA-N Silicon Chemical compound [Si] XUIMIQQOPSSXEZ-UHFFFAOYSA-N 0.000 description 2
- 239000012790 adhesive layer Substances 0.000 description 2
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 2
- IISBACLAFKSPIT-UHFFFAOYSA-N bisphenol A Chemical compound C=1C=C(O)C=CC=1C(C)(C)C1=CC=C(O)C=C1 IISBACLAFKSPIT-UHFFFAOYSA-N 0.000 description 2
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- BVKZGUZCCUSVTD-UHFFFAOYSA-L Carbonate Chemical compound [O-]C([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-L 0.000 description 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 description 1
- 239000003154 D dimer Substances 0.000 description 1
- 102000053602 DNA Human genes 0.000 description 1
- 229920000181 Ethylene propylene rubber Polymers 0.000 description 1
- HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 description 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 1
- JVTAAEKCZFNVCJ-UHFFFAOYSA-M Lactate Chemical compound CC(O)C([O-])=O JVTAAEKCZFNVCJ-UHFFFAOYSA-M 0.000 description 1
- WHXSMMKQMYFTQS-UHFFFAOYSA-N Lithium Chemical compound [Li] WHXSMMKQMYFTQS-UHFFFAOYSA-N 0.000 description 1
- 229920006169 Perfluoroelastomer Polymers 0.000 description 1
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 description 1
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 description 1
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- KVEAILYLMGOETO-UHFFFAOYSA-H dicalcium magnesium diphosphate Chemical compound P(=O)([O-])([O-])[O-].[Mg+2].[Ca+2].[Ca+2].P(=O)([O-])([O-])[O-] KVEAILYLMGOETO-UHFFFAOYSA-H 0.000 description 1
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- QLBHNVFOQLIYTH-UHFFFAOYSA-L dipotassium;2-[2-[bis(carboxymethyl)amino]ethyl-(carboxylatomethyl)amino]acetate Chemical compound [K+].[K+].OC(=O)CN(CC([O-])=O)CCN(CC(O)=O)CC([O-])=O QLBHNVFOQLIYTH-UHFFFAOYSA-L 0.000 description 1
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- NBVXSUQYWXRMNV-UHFFFAOYSA-N fluoromethane Chemical compound FC NBVXSUQYWXRMNV-UHFFFAOYSA-N 0.000 description 1
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- 229960002897 heparin Drugs 0.000 description 1
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- WGCNASOHLSPBMP-UHFFFAOYSA-N hydroxyacetaldehyde Natural products OCC=O WGCNASOHLSPBMP-UHFFFAOYSA-N 0.000 description 1
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Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/505—Containers for the purpose of retaining a material to be analysed, e.g. test tubes flexible containers not provided for above
- B01L3/5055—Hinged, e.g. opposable surfaces
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/04—Exchange or ejection of cartridges, containers or reservoirs
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/04—Closures and closing means
- B01L2300/041—Connecting closures to device or container
- B01L2300/043—Hinged closures
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/04—Closures and closing means
- B01L2300/041—Connecting closures to device or container
- B01L2300/044—Connecting closures to device or container pierceable, e.g. films, membranes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0627—Sensor or part of a sensor is integrated
- B01L2300/0636—Integrated biosensor, microarrays
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
- B01L2300/087—Multiple sequential chambers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/12—Specific details about materials
- B01L2300/123—Flexible; Elastomeric
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
- B01L2400/0487—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T156/00—Adhesive bonding and miscellaneous chemical manufacture
- Y10T156/10—Methods of surface bonding and/or assembly therefor
- Y10T156/1002—Methods of surface bonding and/or assembly therefor with permanent bending or reshaping or surface deformation of self sustaining lamina
- Y10T156/1051—Methods of surface bonding and/or assembly therefor with permanent bending or reshaping or surface deformation of self sustaining lamina by folding
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T29/00—Metal working
- Y10T29/49—Method of mechanical manufacture
- Y10T29/4998—Combined manufacture including applying or shaping of fluent material
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Clinical Laboratory Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Optical Measuring Cells (AREA)
- Sampling And Sample Adjustment (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US28818909P | 2009-12-18 | 2009-12-18 | |
| US61/288,189 | 2009-12-18 | ||
| PCT/US2010/061070 WO2011075663A1 (en) | 2009-12-18 | 2010-12-17 | Integrated hinged cartridge housings for sample analysis |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2784351A1 CA2784351A1 (en) | 2011-06-23 |
| CA2784351C true CA2784351C (en) | 2013-10-08 |
Family
ID=43707811
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2784351A Active CA2784351C (en) | 2009-12-18 | 2010-12-17 | Integrated hinged cartridge housings for sample analysis |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US8747774B2 (enExample) |
| EP (1) | EP2512677B1 (enExample) |
| JP (1) | JP5744906B2 (enExample) |
| CN (1) | CN102686316B (enExample) |
| AU (2) | AU2010330821B2 (enExample) |
| CA (1) | CA2784351C (enExample) |
| WO (1) | WO2011075663A1 (enExample) |
Families Citing this family (64)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE202009018896U1 (de) * | 2008-03-21 | 2014-05-02 | Eppendorf Ag | Küvette, Einsatz, Adapter zur optischen Untersuchung kleiner Flüssigkeitsmengen |
| WO2012019104A1 (en) | 2010-08-05 | 2012-02-09 | Abbott Point Of Care Inc. | Immunoassay method and device with magnetically susceptible bead capture |
| US9233370B2 (en) | 2010-08-05 | 2016-01-12 | Abbott Point Of Care Inc. | Magnetic immunosensor and method of use |
| US9329175B2 (en) | 2010-08-05 | 2016-05-03 | Abbott Point Of Care Inc. | Oscillating immunoassay method and device |
| US11402375B2 (en) | 2010-08-05 | 2022-08-02 | Abbott Point Of Care Inc. | Magnetic immunosensor with trench configuration and method of use |
| US9469871B2 (en) | 2011-04-14 | 2016-10-18 | Corporos Inc. | Methods and apparatus for point-of-care nucleic acid amplification and detection |
| US20130137607A1 (en) * | 2011-11-28 | 2013-05-30 | Tracker Llc | Point of care immunization testing system |
| USD702364S1 (en) * | 2011-12-20 | 2014-04-08 | SYFR, Inc. | Auto-staining cartridge |
| EP3447499A1 (en) | 2011-12-23 | 2019-02-27 | Abbott Point of Care Inc. | Optical assay device with pneumatic sample actuation |
| US9335290B2 (en) | 2011-12-23 | 2016-05-10 | Abbott Point Of Care, Inc. | Integrated test device for optical and electrochemical assays |
| US9140693B2 (en) | 2011-12-23 | 2015-09-22 | Abbott Point Of Care Inc. | Integrated test device for optical detection of microarrays |
| US9194859B2 (en) | 2011-12-23 | 2015-11-24 | Abbott Point Of Care Inc. | Reader devices for optical and electrochemical test devices |
| US8808895B2 (en) * | 2012-06-22 | 2014-08-19 | Apple Inc. | Battery protection structures |
| US9592507B2 (en) | 2012-06-22 | 2017-03-14 | Abbott Point Of Care Inc. | Integrated cartridge housings for sample analysis |
| US10261073B2 (en) * | 2012-10-10 | 2019-04-16 | The Board Of Trustees Of The Leland Stanford Junior University | Compartmentalized integrated biochips |
| JP1479590S (enExample) * | 2012-10-26 | 2016-09-05 | ||
| JP1478903S (enExample) * | 2012-10-26 | 2016-08-29 | ||
| EP2932250B1 (en) | 2012-12-17 | 2017-10-04 | Abbott Point Of Care, Inc. | Self correction for spatial orientation and motion of portable clinical testing devices |
| CN105008920B (zh) * | 2012-12-17 | 2019-03-29 | 雅培医护站股份有限公司 | 便携式临床分析系统中的空间方位确定 |
| US9885706B2 (en) | 2012-12-17 | 2018-02-06 | Abbott Point Of Care Inc. | Portable clinical analysis system for immunometric measurement |
| CN108680734B (zh) | 2012-12-17 | 2021-06-25 | 雅培医护站股份有限公司 | 便携式临床分析系统的操作和核查 |
| US9949674B2 (en) | 2012-12-17 | 2018-04-24 | Abbott Point Of Care Inc. | Portable clinical analysis system for hematocrit measurement |
| US8852877B2 (en) | 2012-12-28 | 2014-10-07 | Abbott Point Of Care Inc. | Apparatus and method for identifying a hook effect and expanding the dynamic range in point of care immunoassays |
| GB201302346D0 (en) * | 2013-02-11 | 2013-03-27 | Epistem Ltd | Sample preparation paper cartridge |
| EP2973098B1 (en) | 2013-03-15 | 2020-05-06 | Abbott Point Of Care, Inc. | Management system for point of care testing |
| WO2014158163A1 (en) * | 2013-03-28 | 2014-10-02 | Hewlett-Packard Development Company, L.P. | Fluid cartridge sub-assembly |
| US20160187239A1 (en) * | 2013-07-29 | 2016-06-30 | Mbio Diagnostics, Inc. | Assay cartridge processing systems and methods and associated assay cartridges |
| WO2015164542A1 (en) * | 2014-04-22 | 2015-10-29 | Nanoscopia (Cayman), Inc. | Sample holder and system for using |
| TWI547695B (zh) * | 2014-11-28 | 2016-09-01 | 宏達國際電子股份有限公司 | 分析裝置與檢測模組 |
| US10379044B2 (en) | 2015-01-20 | 2019-08-13 | Konica Minolta, Inc. | Analysis chip and analysis apparatus |
| CN107667405B (zh) | 2015-06-05 | 2022-02-18 | 雅培医护站股份有限公司 | 用于确保与单次使用测试设备一起使用的护理点仪器的质量合规性的系统和方法 |
| WO2016195894A1 (en) | 2015-06-05 | 2016-12-08 | Abbott Point Of Care Inc. | Systems and methods for assuring quality compliance of point-of-care single-use testing devices |
| US10634602B2 (en) | 2015-06-12 | 2020-04-28 | Cytochip Inc. | Fluidic cartridge for cytometry and additional analysis |
| US10022720B2 (en) | 2015-06-12 | 2018-07-17 | Cytochip Inc. | Fluidic units and cartridges for multi-analyte analysis |
| CN108027310B (zh) * | 2015-07-14 | 2020-12-22 | 芯易诊有限公司 | 流体盒中的体积感测 |
| WO2018065109A1 (en) | 2016-10-07 | 2018-04-12 | Boehringer Ingelheim Vetmedica Gmbh | Cartridge and method for testing a sample |
| USD843009S1 (en) * | 2016-10-14 | 2019-03-12 | Illumina, Inc. | Sample preparation cartridge |
| USD814652S1 (en) * | 2016-10-14 | 2018-04-03 | Spartan Bioscience In. | Cartridge |
| CN110720033A (zh) * | 2016-12-08 | 2020-01-21 | Essenlix 公司 | 分析样品卡和适配器及其使用 |
| KR102807434B1 (ko) | 2017-02-06 | 2025-05-15 | 프리시젼바이오 주식회사 | 유체분석 카트리지 및 이를 포함하는 유체분석 카트리지 어셈블리 |
| CN110944689B (zh) | 2017-06-07 | 2022-12-09 | 施菲姆德控股有限责任公司 | 血管内流体运动设备、系统和使用方法 |
| US11491487B2 (en) | 2017-10-23 | 2022-11-08 | Cytochip Inc. | Devices and methods for measuring analytes and target particles |
| EP3710076B1 (en) | 2017-11-13 | 2023-12-27 | Shifamed Holdings, LLC | Intravascular fluid movement devices, systems, and methods of use |
| WO2019152875A1 (en) | 2018-02-01 | 2019-08-08 | Shifamed Holdings, Llc | Intravascular blood pumps and methods of use and manufacture |
| WO2020028537A1 (en) | 2018-07-31 | 2020-02-06 | Shifamed Holdings, Llc | Intravascaular blood pumps and methods of use |
| US12220570B2 (en) | 2018-10-05 | 2025-02-11 | Shifamed Holdings, Llc | Intravascular blood pumps and methods of use |
| EP3880841B1 (en) | 2019-02-22 | 2023-05-31 | Hewlett-Packard Development Company, L.P. | Nucleic acid detection |
| US11480563B2 (en) * | 2019-03-25 | 2022-10-25 | Testcard Ltd. | Medical test card |
| WO2020242059A1 (en) * | 2019-05-29 | 2020-12-03 | Samsung Electronics Co., Ltd. | Electronic device including hinge structure |
| EP3996797A4 (en) | 2019-07-12 | 2023-08-02 | Shifamed Holdings, LLC | INTRAVASCULAR BLOOD PUMPS AND METHOD OF USE AND METHOD OF MAKING |
| US11654275B2 (en) | 2019-07-22 | 2023-05-23 | Shifamed Holdings, Llc | Intravascular blood pumps with struts and methods of use and manufacture |
| EP4010046A4 (en) | 2019-08-07 | 2023-08-30 | Calomeni, Michael | Catheter blood pumps and collapsible pump housings |
| WO2021062265A1 (en) | 2019-09-25 | 2021-04-01 | Shifamed Holdings, Llc | Intravascular blood pump systems and methods of use and control thereof |
| WO2021062270A1 (en) | 2019-09-25 | 2021-04-01 | Shifamed Holdings, Llc | Catheter blood pumps and collapsible pump housings |
| WO2021062260A1 (en) | 2019-09-25 | 2021-04-01 | Shifamed Holdings, Llc | Catheter blood pumps and collapsible blood conduits |
| US11571697B2 (en) * | 2019-11-07 | 2023-02-07 | Bo Xiao | Sampling and sensing device and method of use thereof |
| WO2021119478A1 (en) | 2019-12-11 | 2021-06-17 | Shifamed Holdings, Llc | Descending aorta and vena cava blood pumps |
| US20240035968A1 (en) * | 2020-08-27 | 2024-02-01 | Mbt Co., Ltd. | Method for detecting target biomolecule in biological sample, disposable optical fiber sensor therefor, and cartridge thereof |
| KR102427990B1 (ko) * | 2020-08-27 | 2022-08-04 | (주)엠비티 | 일회용 광섬유 센서 및 이의 카트리지를 포함하는, fo-lspr을 이용한 생체 분자 진단 시스템 |
| WO2022157916A1 (ja) * | 2021-01-22 | 2022-07-28 | 株式会社エンプラス | 液体取扱システム |
| KR102472080B1 (ko) * | 2021-01-29 | 2022-11-30 | (주)엠비티 | 초정밀 측정을 위한 휴대용 광섬유 국소 표면 플라즈몬 공명 측정 장치 |
| US11839043B2 (en) | 2021-04-29 | 2023-12-05 | Robert Bosch Llc | Electronic device with sealed housing |
| WO2024006876A1 (en) | 2022-06-29 | 2024-01-04 | Abbott Laboratories | Magnetic point-of-care systems and assays for determining gfap in biological samples |
| EP4630823A1 (en) * | 2022-12-09 | 2025-10-15 | Sensill, Inc. | Devices, methods, and systems for measuring and recording a reactant array |
Family Cites Families (57)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3853467A (en) | 1973-08-15 | 1974-12-10 | Gen Electric | Method and apparatus for immunological detection of biological particles |
| SE399768B (sv) * | 1975-09-29 | 1978-02-27 | Lilja Jan E | Kyvett for provtagning, blandning av, provet med ett reagensmedel och direkt utforande av, serskilt optisk, analys av det med reagensmedlet blandade provet |
| US4426451A (en) * | 1981-01-28 | 1984-01-17 | Eastman Kodak Company | Multi-zoned reaction vessel having pressure-actuatable control means between zones |
| US4444711A (en) | 1981-12-21 | 1984-04-24 | Husky Injection Molding Systems Ltd. | Method of operating a two-shot injection-molding machine |
| US4460534A (en) | 1982-09-07 | 1984-07-17 | International Business Machines Corporation | Two-shot injection molding |
| US4997526A (en) | 1985-03-19 | 1991-03-05 | Eic Laboratories, Inc. | Assaying for a biologically active component |
| US4686479A (en) | 1985-07-22 | 1987-08-11 | Young Chung C | Apparatus and control kit for analyzing blood sample values including hematocrit |
| CA1254616A (en) | 1985-11-11 | 1989-05-23 | Calum J. Mcneil | Electrochemical enzymic assay procedures |
| US4954087A (en) | 1988-04-27 | 1990-09-04 | I-Stat Corporation | Static-free interrogating connector for electric components |
| US5096669A (en) | 1988-09-15 | 1992-03-17 | I-Stat Corporation | Disposable sensing device for real time fluid analysis |
| US5200051A (en) | 1988-11-14 | 1993-04-06 | I-Stat Corporation | Wholly microfabricated biosensors and process for the manufacture and use thereof |
| US5063081A (en) | 1988-11-14 | 1991-11-05 | I-Stat Corporation | Method of manufacturing a plurality of uniform microfabricated sensing devices having an immobilized ligand receptor |
| US5081063A (en) | 1989-07-20 | 1992-01-14 | Harris Corporation | Method of making edge-connected integrated circuit structure |
| USD337164S (en) | 1990-07-19 | 1993-07-06 | I-Stat Corporation | Cartridge for a blood monitoring analyzer |
| US5112455A (en) | 1990-07-20 | 1992-05-12 | I Stat Corporation | Method for analytically utilizing microfabricated sensors during wet-up |
| US5254315A (en) | 1991-07-26 | 1993-10-19 | E. I. Du Pont De Nemours And Company | Carrier device |
| JP2922040B2 (ja) | 1992-01-10 | 1999-07-19 | ポーラ化成工業株式会社 | プロテインa分子膜により抗体タンパク質を固定化する方法及び抗体固定膜 |
| US5208649A (en) | 1992-02-20 | 1993-05-04 | University Of Cincinnati | Assembly for front face testing |
| US5807752A (en) | 1992-09-11 | 1998-09-15 | Boehringer Mannheim Corporation | Assay using an unblocked solid phase with immobilized analyte binding partner |
| US5656504A (en) | 1992-10-26 | 1997-08-12 | Pharmacia Biosensor Ab | Method of preventing undesired binding in solid phase assays |
| US5500187A (en) * | 1992-12-08 | 1996-03-19 | Westinghouse Electric Corporation | Disposable optical agglutination assay device and method for use |
| US5821399A (en) | 1993-07-16 | 1998-10-13 | I-Stat Corporation | Automatic test parameters compensation of a real time fluid analysis sensing device |
| CA2175056A1 (en) | 1993-10-28 | 1995-05-04 | Imants R. Lauks | Fluid sample collection and introduction device |
| US5447440A (en) | 1993-10-28 | 1995-09-05 | I-Stat Corporation | Apparatus for assaying viscosity changes in fluid samples and method of conducting same |
| JP3338551B2 (ja) | 1994-03-17 | 2002-10-28 | 塩野義製薬株式会社 | ヒト血清アルブミンの測定方法 |
| JP3368985B2 (ja) | 1994-05-10 | 2003-01-20 | バイエルコーポレーション | 自動供給装置 |
| US5514253A (en) | 1994-07-13 | 1996-05-07 | I-Stat Corporation | Method of measuring gas concentrations and microfabricated sensing device for practicing same |
| US5571410A (en) * | 1994-10-19 | 1996-11-05 | Hewlett Packard Company | Fully integrated miniaturized planar liquid sample handling and analysis device |
| US5597532A (en) | 1994-10-20 | 1997-01-28 | Connolly; James | Apparatus for determining substances contained in a body fluid |
| JP3839524B2 (ja) * | 1995-06-07 | 2006-11-01 | アジレント・テクノロジーズ・インク | 小型化全分析システム |
| US5916522A (en) | 1997-08-07 | 1999-06-29 | Careside, Inc. | Electrochemical analytical cartridge |
| US5919711A (en) * | 1997-08-07 | 1999-07-06 | Careside, Inc. | Analytical cartridge |
| SE9703314D0 (sv) | 1997-09-15 | 1997-09-15 | Sangtec Medical Ab | Capacity affinity sensor |
| DE69819996T2 (de) | 1997-09-27 | 2004-09-02 | Horiba Ltd. | Gerät für die Zählung von Blutzellen und zur immunologischen Bestimmung unter Verwendung von Vollblut |
| US6030827A (en) | 1998-01-23 | 2000-02-29 | I-Stat Corporation | Microfabricated aperture-based sensor |
| US6395235B1 (en) | 1998-08-21 | 2002-05-28 | Argonaut Technologies, Inc. | Devices and methods for accessing reaction vessels |
| US6296796B1 (en) | 1999-02-02 | 2001-10-02 | Trw Inc. | Method for molding a two-material part using a rotatable mold insert member |
| US6475372B1 (en) | 2000-02-02 | 2002-11-05 | Lifescan, Inc. | Electrochemical methods and devices for use in the determination of hematocrit corrected analyte concentrations |
| US20020019062A1 (en) | 1999-06-18 | 2002-02-14 | Peter Lea | Assay devices |
| US6750053B1 (en) | 1999-11-15 | 2004-06-15 | I-Stat Corporation | Apparatus and method for assaying coagulation in fluid samples |
| KR100348351B1 (ko) | 2000-05-24 | 2002-08-09 | 주식회사 바이오디지트 | 전기화학 멤브레인 스트립 바이오센서 |
| US20020155033A1 (en) | 2000-10-06 | 2002-10-24 | Protasis Corporation | Fluid Separate conduit cartridge |
| FI118061B (fi) | 2001-09-24 | 2007-06-15 | Beanor Oy | Menetelmä ja bioanturi analyysiä varten |
| US7419821B2 (en) | 2002-03-05 | 2008-09-02 | I-Stat Corporation | Apparatus and methods for analyte measurement and immunoassay |
| US20030224531A1 (en) | 2002-05-29 | 2003-12-04 | Brennen Reid A. | Microplate with an integrated microfluidic system for parallel processing minute volumes of fluids |
| US7537137B2 (en) | 2002-10-10 | 2009-05-26 | Csp Technologies, Inc. | Resealable moisture tight container assembly for strips and the like having a lip snap seal |
| ATE478812T1 (de) | 2002-10-10 | 2010-09-15 | Csp Technologies Inc | Wiederverschliessbare, feuchtigkeitsdichte behälter für streifen und ähnliches |
| US7263501B2 (en) | 2003-03-11 | 2007-08-28 | I-Stat Corporation | Point-of-care inventory management system and method |
| US7682833B2 (en) | 2003-09-10 | 2010-03-23 | Abbott Point Of Care Inc. | Immunoassay device with improved sample closure |
| WO2006041383A1 (en) | 2004-10-15 | 2006-04-20 | LÖFMAN, Emelie | Packaging for flat objects and method for producing the packaging |
| GB2433926A (en) | 2005-12-22 | 2007-07-11 | Lifescan Scotland Inc | Container with RFID for storing calibration information |
| CA2662751C (en) | 2006-09-06 | 2012-10-16 | Csp Technologies, Inc. | Non-round moisture-tight re-sealable containers with round sealing surfaces |
| US7712610B2 (en) | 2006-10-26 | 2010-05-11 | Lifescan Scotland Limited | Sensor vial having a deformable seal |
| US8057423B2 (en) * | 2007-07-05 | 2011-11-15 | Baxter International Inc. | Dialysis system having disposable cassette |
| JP2009121985A (ja) * | 2007-11-15 | 2009-06-04 | Fujifilm Corp | マイクロ流路チップ、マイクロ流路チップを使用するマイクロ流路チップ処理装置及びマイクロ流路チップ処理方法 |
| US8216529B2 (en) | 2008-09-15 | 2012-07-10 | Abbott Point Of Care Inc. | Fluid-containing pouches with reduced gas exchange and methods for making same |
| WO2010040103A1 (en) * | 2008-10-03 | 2010-04-08 | Micronics, Inc. | Microfluidic apparatus and methods for performing blood typing and crossmatching |
-
2010
- 2010-12-17 WO PCT/US2010/061070 patent/WO2011075663A1/en not_active Ceased
- 2010-12-17 EP EP10798910.5A patent/EP2512677B1/en active Active
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- 2014-06-09 US US14/299,259 patent/US9415389B2/en active Active
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| AU2014210593B2 (en) | 2016-12-22 |
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| EP2512677B1 (en) | 2018-08-15 |
| EP2512677A1 (en) | 2012-10-24 |
| US20110150705A1 (en) | 2011-06-23 |
| CN102686316B (zh) | 2015-05-06 |
| US20140301915A1 (en) | 2014-10-09 |
| AU2014210593A1 (en) | 2014-08-28 |
| JP5744906B2 (ja) | 2015-07-08 |
| AU2010330821B2 (en) | 2014-05-08 |
| WO2011075663A1 (en) | 2011-06-23 |
| AU2010330821A1 (en) | 2012-07-05 |
| US9415389B2 (en) | 2016-08-16 |
| CN102686316A (zh) | 2012-09-19 |
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