CA2781474C - Fibronectin: growth factor chimeras - Google Patents
Fibronectin: growth factor chimeras Download PDFInfo
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- CA2781474C CA2781474C CA2781474A CA2781474A CA2781474C CA 2781474 C CA2781474 C CA 2781474C CA 2781474 A CA2781474 A CA 2781474A CA 2781474 A CA2781474 A CA 2781474A CA 2781474 C CA2781474 C CA 2781474C
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- Prior art keywords
- growth factor
- igf
- fibronectin
- protein complex
- isolated protein
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- XYJRXVWERLGGKC-UHFFFAOYSA-D pentacalcium;hydroxide;triphosphate Chemical compound [OH-].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O XYJRXVWERLGGKC-UHFFFAOYSA-D 0.000 description 1
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/50—Fusion polypeptide containing protease site
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Toxicology (AREA)
- Dermatology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Oncology (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Materials For Medical Uses (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US12/627,647 US20100143442A1 (en) | 2003-02-05 | 2009-11-30 | Growth factor complexes and modulation of cell migration and growth |
| US12/627,647 | 2009-11-30 | ||
| US12/793,386 US8871709B2 (en) | 2003-02-05 | 2010-06-03 | Synthetic chimeric proteins comprising epidermal growth factor and vitronectin |
| US12/793,386 | 2010-06-03 | ||
| PCT/AU2010/001613 WO2011063477A1 (en) | 2009-11-30 | 2010-11-30 | Fibronectin: growth factor chimeras |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2781474A1 CA2781474A1 (en) | 2011-06-03 |
| CA2781474C true CA2781474C (en) | 2019-06-18 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2781474A Expired - Fee Related CA2781474C (en) | 2009-11-30 | 2010-11-30 | Fibronectin: growth factor chimeras |
Country Status (12)
| Country | Link |
|---|---|
| EP (1) | EP2507261B1 (enExample) |
| JP (1) | JP2013511960A (enExample) |
| KR (1) | KR101930916B1 (enExample) |
| CN (1) | CN102725308A (enExample) |
| AU (1) | AU2010324554B2 (enExample) |
| BR (1) | BR112012013035A8 (enExample) |
| CA (1) | CA2781474C (enExample) |
| ES (1) | ES2619938T3 (enExample) |
| NZ (1) | NZ600454A (enExample) |
| RU (1) | RU2012127364A (enExample) |
| WO (1) | WO2011063477A1 (enExample) |
| ZA (1) | ZA201203915B (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8871709B2 (en) * | 2003-02-05 | 2014-10-28 | Queensland University of Technolgy | Synthetic chimeric proteins comprising epidermal growth factor and vitronectin |
| CN103834664B (zh) * | 2014-03-27 | 2016-05-04 | 吉林大学 | 重组表皮生长因子egf及其制备方法 |
| CA3040467C (en) * | 2016-10-14 | 2023-10-31 | Neomatrix Therapeutics, Inc | Peptides derived from fibronectin with improved bioactivity and reduced susceptibility to neutrophil elastase degradation |
| WO2019010533A1 (en) * | 2017-07-12 | 2019-01-17 | Factor Therapeutics Limited | TREATMENT OF OCULAR DISORDERS |
| CN110123732A (zh) * | 2019-04-03 | 2019-08-16 | 广州市拉凯尔干细胞研究所 | 一种含有纤连蛋白化妆品原料制备方法 |
| KR102440312B1 (ko) * | 2020-08-28 | 2022-09-05 | 한국해양과학기술원 | 온도안정성을 향상시킨 fgf7 폴리펩타이드 및 그 용도 |
| CN119264240B (zh) * | 2024-09-10 | 2025-03-25 | 浙江诸暨聚源生物技术有限公司 | 功能增强的重组纤连蛋白及其制备方法和应用 |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| US4843000A (en) | 1979-12-26 | 1989-06-27 | Syntex (U.S.A.) Inc. | Simultaneous calibration heterogeneous immunoassay |
| US4849338A (en) | 1982-07-16 | 1989-07-18 | Syntex (U.S.A.) Inc. | Simultaneous calibration heterogeneous immunoassay |
| US4366241A (en) | 1980-08-07 | 1982-12-28 | Syva Company | Concentrating zone method in heterogeneous immunoassays |
| GB8607679D0 (en) | 1986-03-27 | 1986-04-30 | Winter G P | Recombinant dna product |
| US5091513A (en) | 1987-05-21 | 1992-02-25 | Creative Biomolecules, Inc. | Biosynthetic antibody binding sites |
| CA1341598C (en) | 1988-07-15 | 2009-09-29 | Central Sydney Area Health Service | Acid-labile sub-unit (als) of insulin-like growth factor binding proteincomplex |
| US6090790A (en) | 1989-12-14 | 2000-07-18 | Eriksson; Elof | Gene delivery by microneedle injection |
| JP2866134B2 (ja) * | 1990-02-05 | 1999-03-08 | 寳酒造株式会社 | 機能性ポリペプチド |
| AU649066B2 (en) | 1990-07-25 | 1994-05-12 | Syngene, Inc. | Circular extension for generating multiple nucleic acid complements |
| US6054122A (en) | 1990-11-27 | 2000-04-25 | The American National Red Cross | Supplemented and unsupplemented tissue sealants, methods of their production and use |
| JP2829405B2 (ja) * | 1991-10-14 | 1998-11-25 | 寳酒造株式会社 | 機能性ポリペプチド |
| US5958764A (en) | 1992-04-30 | 1999-09-28 | Baylor College Of Medicine | Specific expression vectors and methods of use |
| AU6136694A (en) | 1993-02-12 | 1994-08-29 | Repligen Corporation | Methods for generating broadly neutralizing anti-hiv antibodies and antigens capable of eliciting same |
| US5422252A (en) | 1993-06-04 | 1995-06-06 | Becton, Dickinson And Company | Simultaneous amplification of multiple targets |
| US5962427A (en) | 1994-02-18 | 1999-10-05 | The Regent Of The University Of Michigan | In vivo gene transfer methods for wound healing |
| AUPM672594A0 (en) | 1994-07-08 | 1994-08-04 | Royal Children's Hospital Research Foundation | A method for the prophylaxis and/or treatment of proliferative and/or inflammatory skin disorders |
| DE69518437T2 (de) * | 1994-11-29 | 2001-02-08 | Takara Shuzo Co., Ltd. | Verfahren zur herstellung transformierter zellen |
| ES2259182T3 (es) * | 1995-11-13 | 2006-09-16 | Takara Bio Inc. | Metodo de introduccion de genes en celulas diana por medio de retrovirus. |
| JP3974941B2 (ja) | 1995-11-21 | 2007-09-12 | イェール ユニバーシティ | 単分子セグメントの増幅および検出 |
| US5752019A (en) | 1995-12-22 | 1998-05-12 | International Business Machines Corporation | System and method for confirmationally-flexible molecular identification |
| US5835382A (en) | 1996-04-26 | 1998-11-10 | The Scripps Research Institute | Small molecule mimetics of erythropoietin |
| US6077987A (en) | 1997-09-04 | 2000-06-20 | North Shore-Long Island Jewish Research Institute | Genetic engineering of cells to enhance healing and tissue regeneration |
| WO1999047070A1 (en) | 1998-03-18 | 1999-09-23 | Wake Forest University | Improved implantable biomaterials, compositions and methods for their preparation and uses thereof |
| AUPP298498A0 (en) | 1998-04-17 | 1998-05-07 | Gropep Pty Ltd | Matrix binding factor |
| US6436897B2 (en) | 1998-06-01 | 2002-08-20 | Celtrix Pharmaceuticals, Inc. | Pharmaceutical formulations for IGF/IGFBP |
| WO2000055206A1 (en) | 1999-03-18 | 2000-09-21 | The Hope Heart Institute | Endothelial cell stimulation by a complex of fibronectin and vascular endothelial growth factor |
| AU2003900481A0 (en) * | 2003-02-05 | 2003-02-20 | Queensland University Of Technology | Synthetic modulators of cell migration and growth |
| JP2008125460A (ja) * | 2006-11-22 | 2008-06-05 | Institute Of Physical & Chemical Research | フィブリン結合性成長因子 |
| US8759300B2 (en) * | 2007-06-14 | 2014-06-24 | The Research Foundation For The State University Of New York | Polypeptides and methods of use |
-
2010
- 2010-11-30 KR KR1020127016766A patent/KR101930916B1/ko not_active Expired - Fee Related
- 2010-11-30 ES ES10832439.3T patent/ES2619938T3/es active Active
- 2010-11-30 WO PCT/AU2010/001613 patent/WO2011063477A1/en not_active Ceased
- 2010-11-30 BR BR112012013035A patent/BR112012013035A8/pt not_active Application Discontinuation
- 2010-11-30 NZ NZ600454A patent/NZ600454A/en not_active IP Right Cessation
- 2010-11-30 AU AU2010324554A patent/AU2010324554B2/en not_active Ceased
- 2010-11-30 EP EP10832439.3A patent/EP2507261B1/en not_active Not-in-force
- 2010-11-30 RU RU2012127364/10A patent/RU2012127364A/ru not_active Application Discontinuation
- 2010-11-30 JP JP2012540231A patent/JP2013511960A/ja active Pending
- 2010-11-30 CN CN201080062313XA patent/CN102725308A/zh active Pending
- 2010-11-30 CA CA2781474A patent/CA2781474C/en not_active Expired - Fee Related
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2012
- 2012-05-29 ZA ZA2012/03915A patent/ZA201203915B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CN102725308A (zh) | 2012-10-10 |
| ZA201203915B (en) | 2018-11-28 |
| EP2507261B1 (en) | 2016-12-21 |
| BR112012013035A8 (pt) | 2018-04-03 |
| ES2619938T3 (es) | 2017-06-27 |
| KR101930916B1 (ko) | 2018-12-19 |
| EP2507261A1 (en) | 2012-10-10 |
| AU2010324554A1 (en) | 2012-06-21 |
| EP2507261A4 (en) | 2013-04-10 |
| NZ600454A (en) | 2014-10-31 |
| RU2012127364A (ru) | 2014-01-10 |
| WO2011063477A1 (en) | 2011-06-03 |
| KR20120114277A (ko) | 2012-10-16 |
| JP2013511960A (ja) | 2013-04-11 |
| AU2010324554B2 (en) | 2014-07-31 |
| BR112012013035A2 (pt) | 2017-05-16 |
| CA2781474A1 (en) | 2011-06-03 |
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Legal Events
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| EEER | Examination request |
Effective date: 20161110 |
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| MKLA | Lapsed |
Effective date: 20201130 |