CA2773242C - Automatic applicator for liquid pharmaceutical preparations, particularly for insulin - Google Patents
Automatic applicator for liquid pharmaceutical preparations, particularly for insulin Download PDFInfo
- Publication number
- CA2773242C CA2773242C CA2773242A CA2773242A CA2773242C CA 2773242 C CA2773242 C CA 2773242C CA 2773242 A CA2773242 A CA 2773242A CA 2773242 A CA2773242 A CA 2773242A CA 2773242 C CA2773242 C CA 2773242C
- Authority
- CA
- Canada
- Prior art keywords
- dose
- spring
- coupling sleeve
- housing
- plunger
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 239000007788 liquid Substances 0.000 title claims abstract description 14
- 239000000825 pharmaceutical preparation Substances 0.000 title claims abstract description 11
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 title abstract description 46
- 102000004877 Insulin Human genes 0.000 title abstract description 23
- 108090001061 Insulin Proteins 0.000 title abstract description 23
- 229940125396 insulin Drugs 0.000 title abstract description 23
- 230000000903 blocking effect Effects 0.000 claims abstract description 13
- 238000002347 injection Methods 0.000 claims abstract description 13
- 239000007924 injection Substances 0.000 claims abstract description 13
- 230000008878 coupling Effects 0.000 claims description 35
- 238000010168 coupling process Methods 0.000 claims description 35
- 238000005859 coupling reaction Methods 0.000 claims description 35
- 230000007246 mechanism Effects 0.000 claims description 12
- 238000007689 inspection Methods 0.000 claims description 11
- 238000006073 displacement reaction Methods 0.000 claims description 6
- 238000000034 method Methods 0.000 claims 8
- 230000006835 compression Effects 0.000 claims 2
- 238000007906 compression Methods 0.000 claims 2
- 239000003814 drug Substances 0.000 abstract description 22
- 238000010276 construction Methods 0.000 description 6
- 230000001681 protective effect Effects 0.000 description 2
- 206010012601 diabetes mellitus Diseases 0.000 description 1
- 230000001131 transforming effect Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31533—Dosing mechanisms, i.e. setting a dose
- A61M5/31535—Means improving security or handling thereof, e.g. blocking means, means preventing insufficient dosing, means allowing correction of overset dose
- A61M5/31543—Means improving security or handling thereof, e.g. blocking means, means preventing insufficient dosing, means allowing correction of overset dose piston rod reset means, i.e. means for causing or facilitating retraction of piston rod to its starting position during cartridge change
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
- A61M5/2033—Spring-loaded one-shot injectors with or without automatic needle insertion
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31533—Dosing mechanisms, i.e. setting a dose
- A61M5/31535—Means improving security or handling thereof, e.g. blocking means, means preventing insufficient dosing, means allowing correction of overset dose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31533—Dosing mechanisms, i.e. setting a dose
- A61M5/31545—Setting modes for dosing
- A61M5/31548—Mechanically operated dose setting member
- A61M5/3155—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe
- A61M5/31551—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe including axial movement of dose setting member
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31533—Dosing mechanisms, i.e. setting a dose
- A61M5/31545—Setting modes for dosing
- A61M5/31548—Mechanically operated dose setting member
- A61M5/3155—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe
- A61M5/31553—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe without axial movement of dose setting member
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31533—Dosing mechanisms, i.e. setting a dose
- A61M5/31545—Setting modes for dosing
- A61M5/31548—Mechanically operated dose setting member
- A61M5/31555—Mechanically operated dose setting member by purely axial movement of dose setting member, e.g. during setting or filling of a syringe
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
- A61M5/31576—Constructional features or modes of drive mechanisms for piston rods
- A61M5/31583—Constructional features or modes of drive mechanisms for piston rods based on rotational translation, i.e. movement of piston rod is caused by relative rotation between the user activated actuator and the piston rod
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
- A61M2005/2006—Having specific accessories
- A61M2005/202—Having specific accessories cocking means, e.g. to bias the main drive spring of an injector
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
- A61M2005/2403—Ampoule inserted into the ampoule holder
- A61M2005/2407—Ampoule inserted into the ampoule holder from the rear
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
- A61M2005/2485—Ampoule holder connected to rest of syringe
- A61M2005/2488—Ampoule holder connected to rest of syringe via rotation, e.g. threads or bayonet
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M2005/3114—Filling or refilling
- A61M2005/3115—Filling or refilling spring-assisted
Landscapes
- Health & Medical Sciences (AREA)
- Vascular Medicine (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PLP.389427 | 2009-10-30 | ||
| PL389427A PL215310B1 (pl) | 2009-10-30 | 2009-10-30 | Automatyczny aplikator, zwlaszcza do insuliny |
| PCT/EP2010/054128 WO2010089418A2 (en) | 2009-10-30 | 2010-03-29 | Automatic applicator for liquid pharmaceutical preparations, particularly for insulin |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2773242A1 CA2773242A1 (en) | 2010-08-12 |
| CA2773242C true CA2773242C (en) | 2019-03-12 |
Family
ID=42542446
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2773242A Active CA2773242C (en) | 2009-10-30 | 2010-03-29 | Automatic applicator for liquid pharmaceutical preparations, particularly for insulin |
Country Status (13)
| Country | Link |
|---|---|
| US (4) | US9566386B2 (cg-RX-API-DMAC7.html) |
| EP (3) | EP2493533B1 (cg-RX-API-DMAC7.html) |
| JP (3) | JP5802211B2 (cg-RX-API-DMAC7.html) |
| KR (2) | KR101988582B1 (cg-RX-API-DMAC7.html) |
| CN (1) | CN102573962B (cg-RX-API-DMAC7.html) |
| AU (1) | AU2010210090B2 (cg-RX-API-DMAC7.html) |
| BR (1) | BR112012005853B8 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2773242C (cg-RX-API-DMAC7.html) |
| DK (2) | DK2493533T3 (cg-RX-API-DMAC7.html) |
| ES (2) | ES2635368T3 (cg-RX-API-DMAC7.html) |
| PL (1) | PL215310B1 (cg-RX-API-DMAC7.html) |
| RU (1) | RU2527156C2 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2010089418A2 (cg-RX-API-DMAC7.html) |
Families Citing this family (45)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6663602B2 (en) | 2000-06-16 | 2003-12-16 | Novo Nordisk A/S | Injection device |
| ES2334046T3 (es) | 2004-10-21 | 2010-03-04 | Novo Nordisk A/S | Mecanismo de disminucion para pluma regulable. |
| PL2023982T3 (pl) | 2006-05-18 | 2012-11-30 | Novo Nordisk As | Urządzenie wstrzykujące ze środkami blokującymi |
| US7959598B2 (en) | 2008-08-20 | 2011-06-14 | Asante Solutions, Inc. | Infusion pump systems and methods |
| GB0918145D0 (en) | 2009-10-16 | 2009-12-02 | Owen Mumford Ltd | Injector apparatus |
| PL215310B1 (pl) * | 2009-10-30 | 2013-11-29 | Kappa Medilab Spolka Z Ograniczona Odpowiedzialnoscia | Automatyczny aplikator, zwlaszcza do insuliny |
| GB201018827D0 (en) | 2010-11-08 | 2010-12-22 | Owen Mumford Ltd | Injection device |
| EP2468329A1 (en) * | 2010-12-21 | 2012-06-27 | Sanofi-Aventis Deutschland GmbH | Auto injector with a torsion spring |
| EP2707063B1 (en) * | 2011-05-12 | 2019-06-26 | SHL Medical AG | Medical delivery device with dose re-setting |
| US9533106B2 (en) | 2011-12-29 | 2017-01-03 | Novo Nordisk A/S | Torsion-spring based wind-up auto injector pen with dial-up/dial-down mechanism |
| PL220720B1 (pl) * | 2012-02-08 | 2015-12-31 | Copernicus Spółka Z Ograniczoną Odpowiedzialnością | Urządzenie wstrzykujące z mechanizmem resetu dawki |
| WO2013149186A1 (en) | 2012-03-30 | 2013-10-03 | Insulet Corporation | Fluid delivery device with transcutaneous access tool, insertion mechansim and blood glucose monitoring for use therewith |
| GB2501897B (en) | 2012-05-09 | 2014-09-03 | Owen Mumford Ltd | Injection devices |
| TR201808673T4 (tr) * | 2012-05-30 | 2018-07-23 | Sanofi Aventis Deutschland | Bir ilaç dağıtım cihazına yönelik tahrik mekanizması ve ilaç dağıtım cihazı. |
| AU2013269952A1 (en) | 2012-05-31 | 2014-11-13 | Novo Nordisk A/S | Dial-down mechanism for wind-up pen |
| TR201808342T4 (tr) | 2013-05-07 | 2018-07-23 | Sanofi Aventis Deutschland | Bir enjeksiyon cihazına bağlanmaya yönelik bir tamamlayıcı cihaz. |
| WO2014191189A1 (en) * | 2013-05-27 | 2014-12-04 | Sanofi-Aventis Deutschland Gmbh | Assembly for a drug delivery device and drug delivery device |
| EP3021896A1 (en) * | 2013-07-17 | 2016-05-25 | Sanofi | Counting mechanism for a drug delivery device |
| US9561324B2 (en) | 2013-07-19 | 2017-02-07 | Bigfoot Biomedical, Inc. | Infusion pump system and method |
| US10569015B2 (en) | 2013-12-02 | 2020-02-25 | Bigfoot Biomedical, Inc. | Infusion pump system and method |
| EP3094361B1 (en) * | 2014-01-13 | 2018-03-14 | Novo Nordisk A/S | Transmission arrangement for motorized drug delivery device |
| CN106794311A (zh) | 2014-10-08 | 2017-05-31 | 诺和诺德股份有限公司 | 用于注射装置的扭力弹簧和包括这种扭力弹簧的注射装置 |
| EP3223884B1 (en) * | 2014-11-24 | 2023-05-10 | Sanofi | Drug delivery device with variable piston force |
| WO2016135237A1 (en) | 2015-02-27 | 2016-09-01 | Novo Nordisk A/S | Drug delivery device with dose reset mechanism |
| EP3064239A1 (en) * | 2015-03-05 | 2016-09-07 | Carebay Europe Ltd. | Medicament delivery device with information provider system |
| US9878097B2 (en) | 2015-04-29 | 2018-01-30 | Bigfoot Biomedical, Inc. | Operating an infusion pump system |
| EP3288613B1 (en) | 2015-04-29 | 2021-12-08 | Novo Nordisk A/S | Drug delivery device with spring mechanism |
| CN106259891A (zh) * | 2015-05-28 | 2017-01-04 | 上海旺旺食品集团有限公司 | 一种益生菌口含片及其制备方法 |
| PL414382A1 (pl) * | 2015-10-15 | 2017-04-24 | Copernicus Spółka Z Ograniczoną Odpowiedzialnością | Mechanizm nastawczy, w szczególności do dozowania |
| PL227678B1 (pl) | 2015-12-22 | 2018-01-31 | Copernicus Spolka Z Ograniczona Odpowiedzialnoscia | Układ sterująco-napędowy dla urządzenia do iniekcji oraz urządzenie do iniekcji zaopatrzone w taki układ |
| EP3374900B1 (en) | 2016-01-05 | 2025-06-11 | Insulet Corporation | Operating multi-modal medicine delivery systems |
| US10449294B1 (en) | 2016-01-05 | 2019-10-22 | Bigfoot Biomedical, Inc. | Operating an infusion pump system |
| HK1256995A1 (zh) | 2016-01-14 | 2019-10-11 | Bigfoot Biomedical, Inc. | 药物输送设备、系统和方法中的阻塞解决方案 |
| CN106039475B (zh) * | 2016-05-18 | 2019-08-02 | 苏州鹏烨医疗科技有限公司 | 一种注射笔 |
| PL3108914T3 (pl) | 2016-07-07 | 2019-08-30 | Copernicus Sp. Z O.O. | Urządzenie wstrzykujące do podawania określonej liczby jednakowych dawek substancji płynnej |
| EP3506969A1 (en) | 2016-08-31 | 2019-07-10 | Novo Nordisk A/S | Drug delivery device with over-torque protection mechanism |
| US10302598B2 (en) | 2016-10-24 | 2019-05-28 | General Electric Company | Corrosion and crack detection for fastener nuts |
| PL232651B1 (pl) * | 2017-07-18 | 2019-07-31 | Copernicus Spolka Z Ograniczona Odpowiedzialnoscia | Sprzęgło z systemem blokowania dla medycznego urządzenia wstrzykującego |
| CN107308523A (zh) * | 2017-08-08 | 2017-11-03 | 甘肃成纪生物药业有限公司 | 微调注射笔 |
| PL237295B1 (pl) * | 2018-11-28 | 2021-04-06 | Copernicus Spolka Z Ograniczona Odpowiedzialnoscia | Mechanizm sterujący aplikatora i sposób jego montażu |
| RU2729432C1 (ru) * | 2019-10-23 | 2020-08-06 | Общество с ограниченной ответственностью «НЭКСТ БИО» | Устройство для доставки лекарственного средства |
| CN111558102B (zh) * | 2020-05-25 | 2020-12-15 | 宋娜 | 一种带自动上药装置的胰岛素注射盒 |
| CN115252094A (zh) * | 2021-04-30 | 2022-11-01 | 张任贤 | 一种注射器推进器 |
| CN113730729B (zh) * | 2021-09-13 | 2023-08-18 | 郑州瑞宇科技有限公司 | 一种手电动一体胰岛素注射笔及其注射方法 |
| KR102726943B1 (ko) * | 2022-01-04 | 2024-11-07 | 이오플로우(주) | 약액 주입 장치 |
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2009
- 2009-10-30 PL PL389427A patent/PL215310B1/pl unknown
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2010
- 2010-03-29 RU RU2012117569/14A patent/RU2527156C2/ru active
- 2010-03-29 KR KR1020187014935A patent/KR101988582B1/ko not_active Expired - Fee Related
- 2010-03-29 DK DK10713161.7T patent/DK2493533T3/da active
- 2010-03-29 AU AU2010210090A patent/AU2010210090B2/en not_active Ceased
- 2010-03-29 EP EP10713161.7A patent/EP2493533B1/en not_active Not-in-force
- 2010-03-29 WO PCT/EP2010/054128 patent/WO2010089418A2/en not_active Ceased
- 2010-03-29 DK DK15151119.3T patent/DK2913075T3/en active
- 2010-03-29 ES ES15151119.3T patent/ES2635368T3/es active Active
- 2010-03-29 EP EP17168878.1A patent/EP3235531A1/en not_active Withdrawn
- 2010-03-29 ES ES10713161.7T patent/ES2536838T3/es active Active
- 2010-03-29 CN CN201080046137.0A patent/CN102573962B/zh active Active
- 2010-03-29 KR KR1020127011308A patent/KR101863938B1/ko active Active
- 2010-03-29 JP JP2012535690A patent/JP5802211B2/ja not_active Expired - Fee Related
- 2010-03-29 EP EP15151119.3A patent/EP2913075B1/en active Active
- 2010-03-29 CA CA2773242A patent/CA2773242C/en active Active
- 2010-03-29 BR BR112012005853A patent/BR112012005853B8/pt active IP Right Grant
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2012
- 2012-04-28 US US13/459,147 patent/US9566386B2/en not_active Expired - Fee Related
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2015
- 2015-02-12 JP JP2015025509A patent/JP2015120003A/ja active Pending
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2016
- 2016-12-22 US US15/388,385 patent/US9895495B2/en active Active
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2017
- 2017-04-06 JP JP2017075871A patent/JP2017136426A/ja active Pending
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2018
- 2018-01-12 US US15/869,632 patent/US10064999B2/en active Active
- 2018-09-04 US US16/120,548 patent/US20190099556A1/en not_active Abandoned
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