CA2769885A1 - Procede et appareil utilisables dans le cadre d'un processus d'extraction d'antigenes - Google Patents
Procede et appareil utilisables dans le cadre d'un processus d'extraction d'antigenes Download PDFInfo
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- CA2769885A1 CA2769885A1 CA2769885A CA2769885A CA2769885A1 CA 2769885 A1 CA2769885 A1 CA 2769885A1 CA 2769885 A CA2769885 A CA 2769885A CA 2769885 A CA2769885 A CA 2769885A CA 2769885 A1 CA2769885 A1 CA 2769885A1
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- antigen retrieval
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- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
- G01N1/31—Apparatus therefor
- G01N1/312—Apparatus therefor for samples mounted on planar substrates
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Chemical & Material Sciences (AREA)
- Pathology (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Sampling And Sample Adjustment (AREA)
- Peptides Or Proteins (AREA)
Abstract
L'invention concerne un procédé d'extraction d'antigènes depuis un échantillon tissulaire fixé au formaldéhyde. Ledit procédé comprend les étapes consistant à incuber un échantillon tissulaire fixé au formaldéhyde dans une première solution d'extraction d'antigènes à une température supérieure à 90 °C, à transférer ledit échantillon tissulaire dans une seconde solution d'extraction d'antigènes et à incuber l'échantillon tissulaire dans la seconde solution d'extraction d'antigènes à une température supérieure à 90 °C. L'invention concerne également un nécessaire et un dispositif de mise en place d'échantillons permettant la mise en ?uvre dudit procédé.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US12/547,768 | 2009-08-26 | ||
| US12/547,768 US8067241B2 (en) | 2009-08-26 | 2009-08-26 | Method and apparatus for antigen retrieval process |
| PCT/SE2010/050902 WO2011025442A1 (fr) | 2009-08-26 | 2010-08-23 | Procédé et appareil utilisables dans le cadre d'un processus d'extraction d'antigènes |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2769885A1 true CA2769885A1 (fr) | 2011-03-03 |
| CA2769885C CA2769885C (fr) | 2018-06-26 |
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ID=43625473
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2769885A Expired - Fee Related CA2769885C (fr) | 2009-08-26 | 2010-08-23 | Procede et appareil utilisables dans le cadre d'un processus d'extraction d'antigenes |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US8067241B2 (fr) |
| EP (1) | EP2470877B1 (fr) |
| JP (1) | JP5752688B2 (fr) |
| KR (1) | KR101823697B1 (fr) |
| CN (1) | CN102597740B (fr) |
| AU (1) | AU2010287027B2 (fr) |
| BR (1) | BR112012004141B1 (fr) |
| CA (1) | CA2769885C (fr) |
| HK (1) | HK1173494A1 (fr) |
| NZ (1) | NZ598084A (fr) |
| RU (1) | RU2538022C2 (fr) |
| SG (1) | SG178486A1 (fr) |
| WO (1) | WO2011025442A1 (fr) |
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| US8956859B1 (en) | 2010-08-13 | 2015-02-17 | Aviex Technologies Llc | Compositions and methods for determining successful immunization by one or more vaccines |
| CN106030309B (zh) * | 2013-12-12 | 2019-11-26 | 休斯敦大学系统 | 通用抗原修复化合物及其使用方法 |
| US10203269B2 (en) | 2013-12-12 | 2019-02-12 | University Of Houston System | Method of retrieving elements from fixed tissue |
| CN103712837B (zh) * | 2013-12-29 | 2015-10-28 | 中国人民解放军成都军区总医院 | 悬浮脑片抗原修复压片夹 |
| JP6908531B2 (ja) * | 2015-01-27 | 2021-07-28 | ベンタナ メディカル システムズ， インコーポレイテッド | アルデヒドに基づく固定溶液における長時間浸漬を用いる、組織試料固定法 |
| FR3032797B1 (fr) | 2015-02-13 | 2017-03-03 | Cisbio Bioassays | Procede de quantification d'une proteine d'interet presente dans un echantillon biologique |
| CN110073222A (zh) | 2016-12-21 | 2019-07-30 | 文塔纳医疗系统公司 | 用于试剂递送的方法、系统和固体组合物 |
| JP6877550B2 (ja) | 2016-12-22 | 2021-05-26 | ヴェンタナ メディカル システムズ， インク． | 組織試料用の全自動核酸抽出方法 |
| EP3427829A1 (fr) | 2017-07-12 | 2019-01-16 | Lunaphore Technologies SA | Procédés d'extraction in situ d'antigènes d'un échantillon biologique et son imagerie |
| US10274498B1 (en) | 2018-04-05 | 2019-04-30 | Rarecyte, Inc. | Analyte detection |
| US10330684B1 (en) | 2018-04-05 | 2019-06-25 | Rarecyte, Inc. | Analyte detection |
| CN112684178A (zh) * | 2021-01-06 | 2021-04-20 | 深圳市圣通生物科技有限公司 | 一种免疫组化抗原修复缓冲液及其使用方法 |
| WO2022217084A1 (fr) | 2021-04-09 | 2022-10-13 | Neogenomics Laboratories, Inc. | Accumulation périvasculaire de cellules immunitaires dans le diagnostic et le traitement du cancer |
| CN113552362A (zh) * | 2021-07-23 | 2021-10-26 | 湖北百奥斯生物科技有限公司 | 一种新型信号放大的免疫荧光试剂盒 |
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| AU762808B2 (en) * | 1998-03-24 | 2003-07-03 | Biogenex Laboratories | Automated staining apparatus |
| US7951612B2 (en) * | 1999-07-08 | 2011-05-31 | Lee H. Angros | In situ heat induced antigen recovery and staining apparatus and method |
| AU6079500A (en) | 1999-07-08 | 2001-01-30 | Lee Angros | Antigen recovery and/or staining apparatus and method |
| US20010043884A1 (en) | 1999-12-14 | 2001-11-22 | Ervin Essenfeld | Microwave unit and system for tissue processing |
| JP2002151473A (ja) | 2000-11-13 | 2002-05-24 | Tokyo Electron Ltd | プラズマ処理装置及びその組立方法 |
| JP3797418B2 (ja) * | 2001-05-29 | 2006-07-19 | 茂樹 並松 | 抗原賦活化法及びその抗原賦活剤 |
| US20040029184A1 (en) * | 2002-08-09 | 2004-02-12 | Pickcell Laboratories B.V. | Method for antigen retrieval and submersion fluid compositions for use therein |
| GB0304515D0 (en) | 2003-02-27 | 2003-04-02 | Dakocytomation Denmark As | Standard |
| JP3899407B2 (ja) * | 2003-06-26 | 2007-03-28 | 国立大学法人 鹿児島大学 | 免疫組織化学的染色方法による抗原の検出方法 |
| US20050053626A1 (en) * | 2003-09-05 | 2005-03-10 | Harrington John Ames | Grace process biotechnology patent the cure to the herpes virus |
| JP2008501339A (ja) * | 2004-06-01 | 2008-01-24 | ジェンザイム・コーポレイション | Ａａｖベクターの凝集を防ぐための組成物およびその方法 |
| US7867443B2 (en) | 2004-07-23 | 2011-01-11 | Dako Denmark A/S | Method and apparatus for automated pre-treatment and processing of biological samples |
| JP5335420B2 (ja) * | 2005-05-24 | 2013-11-06 | リー エイチ． アングロス， | ｉｎｓｉｔｕ熱誘導抗原回復・着色装置および方法 |
| WO2007047450A1 (fr) | 2005-10-13 | 2007-04-26 | Aureon Laboratories, Inc. | Analyse immunohistochimique multiplexee in situ |
| CA2619799C (fr) * | 2007-01-30 | 2015-11-24 | Health Research Inc. | Methodes d'evaluation et de mise en oeuvre de traitements de maladies de la prostate |
| ES2385523T3 (es) * | 2007-02-09 | 2012-07-26 | Dako Denmark A/S | Recuperación de antígeno horizontal |
| CN101387641B (zh) * | 2007-09-11 | 2013-11-27 | 深圳市康百得生物科技有限公司 | 一种淡水鱼类肝吸虫快速免疫检测试剂盒和检测方法 |
| WO2009085574A2 (fr) * | 2007-12-28 | 2009-07-09 | Spring Bioscience Corporation | Extraction d'antigènes par énergie micro-onde dans des solvants non aqueux |
| WO2009110936A2 (fr) | 2007-12-28 | 2009-09-11 | Spring Bioscience Corporation | Procédés d’extraction d’antigène pour l’immunohistochimie |
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2009
- 2009-08-26 US US12/547,768 patent/US8067241B2/en active Active
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2010
- 2010-08-23 JP JP2012526689A patent/JP5752688B2/ja active Active
- 2010-08-23 NZ NZ598084A patent/NZ598084A/en not_active IP Right Cessation
- 2010-08-23 SG SG2012011300A patent/SG178486A1/en unknown
- 2010-08-23 AU AU2010287027A patent/AU2010287027B2/en not_active Ceased
- 2010-08-23 CN CN201080038562.5A patent/CN102597740B/zh active Active
- 2010-08-23 BR BR112012004141-0A patent/BR112012004141B1/pt not_active IP Right Cessation
- 2010-08-23 KR KR1020127004876A patent/KR101823697B1/ko active IP Right Grant
- 2010-08-23 CA CA2769885A patent/CA2769885C/fr not_active Expired - Fee Related
- 2010-08-23 RU RU2012106199/05A patent/RU2538022C2/ru active
- 2010-08-23 EP EP10812401.7A patent/EP2470877B1/fr active Active
- 2010-08-23 WO PCT/SE2010/050902 patent/WO2011025442A1/fr active Application Filing
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2011
- 2011-09-22 US US13/239,918 patent/US20120009666A1/en not_active Abandoned
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- 2013-01-15 HK HK13100622.1A patent/HK1173494A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| NZ598084A (en) | 2014-06-27 |
| CN102597740B (zh) | 2015-04-01 |
| BR112012004141A2 (pt) | 2016-03-22 |
| BR112012004141B1 (pt) | 2020-03-10 |
| EP2470877A4 (fr) | 2013-03-13 |
| JP2013503332A (ja) | 2013-01-31 |
| US20110053171A1 (en) | 2011-03-03 |
| CN102597740A (zh) | 2012-07-18 |
| HK1173494A1 (en) | 2013-05-16 |
| WO2011025442A1 (fr) | 2011-03-03 |
| JP5752688B2 (ja) | 2015-07-22 |
| AU2010287027A1 (en) | 2012-03-01 |
| KR101823697B1 (ko) | 2018-01-30 |
| AU2010287027B2 (en) | 2015-03-12 |
| EP2470877B1 (fr) | 2020-06-03 |
| CA2769885C (fr) | 2018-06-26 |
| RU2012106199A (ru) | 2013-10-10 |
| US20120009666A1 (en) | 2012-01-12 |
| US8067241B2 (en) | 2011-11-29 |
| EP2470877A1 (fr) | 2012-07-04 |
| KR20120049897A (ko) | 2012-05-17 |
| SG178486A1 (en) | 2012-03-29 |
| RU2538022C2 (ru) | 2015-01-10 |
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