CA2769251C - 5-fluoro-2-oxopyrimidine- 1(2h)-carboxylate derivatives - Google Patents
5-fluoro-2-oxopyrimidine- 1(2h)-carboxylate derivatives Download PDFInfo
- Publication number
- CA2769251C CA2769251C CA2769251A CA2769251A CA2769251C CA 2769251 C CA2769251 C CA 2769251C CA 2769251 A CA2769251 A CA 2769251A CA 2769251 A CA2769251 A CA 2769251A CA 2769251 C CA2769251 C CA 2769251C
- Authority
- CA
- Canada
- Prior art keywords
- optionally substituted
- compound
- ring system
- benzyl
- phenyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/47—One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
- A01N43/54—1,3-Diazines; Hydrogenated 1,3-diazines
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
- A01N47/08—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
- A01N47/10—Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof
- A01N47/16—Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof the nitrogen atom being part of a heterocyclic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/20—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D239/22—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Dentistry (AREA)
- Wood Science & Technology (AREA)
- Plant Pathology (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Agronomy & Crop Science (AREA)
- General Health & Medical Sciences (AREA)
- Pest Control & Pesticides (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US23223209P | 2009-08-07 | 2009-08-07 | |
| US61/232,232 | 2009-08-07 | ||
| PCT/US2010/044585 WO2011017544A1 (en) | 2009-08-07 | 2010-08-05 | 5-fluoro-2-oxopyrimidine- 1(2h)-carboxylate derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2769251A1 CA2769251A1 (en) | 2011-02-10 |
| CA2769251C true CA2769251C (en) | 2018-05-15 |
Family
ID=43535293
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2769251A Expired - Fee Related CA2769251C (en) | 2009-08-07 | 2010-08-05 | 5-fluoro-2-oxopyrimidine- 1(2h)-carboxylate derivatives |
Country Status (28)
| Country | Link |
|---|---|
| US (1) | US8318758B2 (forum.php) |
| EP (1) | EP2462133B1 (forum.php) |
| JP (1) | JP5818791B2 (forum.php) |
| KR (1) | KR101792286B1 (forum.php) |
| CN (1) | CN102548979B (forum.php) |
| AU (1) | AU2010279408B2 (forum.php) |
| BR (1) | BR112012002807B1 (forum.php) |
| CA (1) | CA2769251C (forum.php) |
| CL (1) | CL2012000314A1 (forum.php) |
| CO (1) | CO6491089A2 (forum.php) |
| CR (1) | CR20120033A (forum.php) |
| DK (1) | DK2462133T3 (forum.php) |
| EA (1) | EA022930B1 (forum.php) |
| EC (1) | ECSP12011651A (forum.php) |
| ES (1) | ES2506169T3 (forum.php) |
| HN (1) | HN2012000261A (forum.php) |
| IL (1) | IL217954A (forum.php) |
| IN (1) | IN2012DN00695A (forum.php) |
| MX (1) | MX2012001623A (forum.php) |
| NI (1) | NI201200019A (forum.php) |
| NZ (1) | NZ597638A (forum.php) |
| PE (1) | PE20120689A1 (forum.php) |
| PL (1) | PL2462133T3 (forum.php) |
| PT (1) | PT2462133E (forum.php) |
| RS (1) | RS53658B1 (forum.php) |
| UA (1) | UA106086C2 (forum.php) |
| WO (1) | WO2011017544A1 (forum.php) |
| ZA (1) | ZA201305992B (forum.php) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5784603B2 (ja) * | 2009-08-07 | 2015-09-24 | ダウ アグロサイエンシィズ エルエルシー | Ｎ１−スルホニル−５−フルオロピリミジノン誘導体 |
| CN104884062B (zh) | 2012-12-28 | 2018-11-06 | 阿达玛马克西姆股份有限公司 | N-(取代的)-5-氟-4-亚氨基-3-甲基-2-氧代-3,4-二氢嘧啶-1(2h)-甲酰胺衍生物 |
| EP3689142A1 (en) * | 2012-12-28 | 2020-08-05 | Adama Makhteshim Ltd. | 1-(substituted-benzoyl)-5-fluoro-4-imino-3-methyl-3,4-dihydropyrimidin-2(1h)-one derivatives |
| AU2013370493B2 (en) * | 2012-12-28 | 2017-08-17 | Adama Makhteshim Ltd. | N-(substituted)-5-fluoro-4-imino-3-methyl-2-oxo-3,4-dihydropyrimidine-1 (2H)-carboxylate derivatives |
| NZ749557A (en) | 2012-12-31 | 2020-01-31 | Adama Makhteshim Ltd | 3-alkyl-5-fluoro-4-substituted-imino-3,4-dihydropyrimidin-2(1h)-one derivatives as fungicides |
| CN111362881A (zh) | 2013-12-31 | 2020-07-03 | 阿达玛马克西姆股份有限公司 | 一种化合物及其制备方法 |
| PT3096619T (pt) | 2013-12-31 | 2025-09-11 | Adama Makhteshim Ltd | Misturas fungicidas sinérgicas para controlo de fungos em cereais |
| WO2016040193A1 (en) | 2014-09-08 | 2016-03-17 | Samumed, Llc | 3-(1h-imidazo[4,5-c]pyridin-2-yl)-1h-pyrazolo[3,4-b]pyridine and therapeutic uses thereof |
| KR20180080262A (ko) | 2015-11-06 | 2018-07-11 | 사뮤메드, 엘엘씨 | 골관절염의 치료 |
| JP7010851B2 (ja) | 2016-06-01 | 2022-02-10 | バイオスプライス セラピューティクス インコーポレイテッド | Ｎ－（５－（３－（７－（３－フルオロフェニル）－３Ｈ－イミダゾ［４，５－ｃ］ピリジン－２－イル）－１Ｈ－インダゾール－５－イル）ピリジン－３－イル）－３－メチルブタンアミドを調製するための方法 |
| IL271950B2 (en) | 2017-07-17 | 2024-06-01 | Adama Makhteshim Ltd | Polymorphs of 5-fluoro-4-imino-3-methyl-1-tosyl-4,3-dihydropyrimidin-2-one |
| BR112021008755A2 (pt) | 2018-11-05 | 2021-08-10 | Adama Makhteshim Ltd. | misturas e composições contendo 5-fluoro-4-imino-3- metil-1-tosil-3,4-dihidropirimidina-2-ona, e métodos de uso. |
| AR120035A1 (es) | 2019-09-23 | 2022-01-26 | Adama Makhteshim Ltd | Proceso para preparar 5-(fluoro-4-imino-3-metil)-1-tosil-3,4-dihidropirimidin-(1h)-ona y derivados del compuesto |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3368938A (en) * | 1966-01-13 | 1968-02-13 | Hoffmann La Roche | Controlling fungi with 5-fluorocytosine |
| JP2000506171A (ja) * | 1996-03-11 | 2000-05-23 | ノバルティス アクチェンゲゼルシャフト | 農薬としてのピリミジン−４−オン誘導体 |
| WO2004037159A2 (en) * | 2002-10-23 | 2004-05-06 | Obetherapy Biotechnology | Compounds, compositions and methods for modulating fat metabolism |
| AU2008249329C1 (en) * | 2007-04-27 | 2013-07-04 | Daiichi Sankyo Company Limited | Nitrogenated aromatic 6-membered ring derivative, and pharmaceutical agent comprising the same |
| EP2647287A1 (en) | 2008-08-01 | 2013-10-09 | Dow AgroSciences LLC | Use of 5-fluorocytosine and its derivatives as fungicides |
-
2010
- 2010-08-05 RS RS20140630A patent/RS53658B1/sr unknown
- 2010-08-05 CN CN201080045339.3A patent/CN102548979B/zh active Active
- 2010-08-05 BR BR112012002807-3A patent/BR112012002807B1/pt active IP Right Grant
- 2010-08-05 NZ NZ597638A patent/NZ597638A/en unknown
- 2010-08-05 KR KR1020127005932A patent/KR101792286B1/ko not_active Expired - Fee Related
- 2010-08-05 JP JP2012523954A patent/JP5818791B2/ja active Active
- 2010-08-05 PL PL10807174T patent/PL2462133T3/pl unknown
- 2010-08-05 AU AU2010279408A patent/AU2010279408B2/en not_active Ceased
- 2010-08-05 EA EA201270255A patent/EA022930B1/ru not_active IP Right Cessation
- 2010-08-05 PT PT108071747T patent/PT2462133E/pt unknown
- 2010-08-05 DK DK10807174.7T patent/DK2462133T3/en active
- 2010-08-05 UA UAA201202680A patent/UA106086C2/uk unknown
- 2010-08-05 EP EP10807174.7A patent/EP2462133B1/en active Active
- 2010-08-05 IN IN695DEN2012 patent/IN2012DN00695A/en unknown
- 2010-08-05 WO PCT/US2010/044585 patent/WO2011017544A1/en not_active Ceased
- 2010-08-05 ES ES10807174.7T patent/ES2506169T3/es active Active
- 2010-08-05 PE PE2012000170A patent/PE20120689A1/es not_active Application Discontinuation
- 2010-08-05 MX MX2012001623A patent/MX2012001623A/es active IP Right Grant
- 2010-08-05 CA CA2769251A patent/CA2769251C/en not_active Expired - Fee Related
- 2010-08-05 US US12/851,304 patent/US8318758B2/en active Active
-
2012
- 2012-01-18 CR CR20120033A patent/CR20120033A/es unknown
- 2012-01-27 CO CO12012413A patent/CO6491089A2/es active IP Right Grant
- 2012-02-02 HN HN2012000261A patent/HN2012000261A/es unknown
- 2012-02-03 NI NI201200019A patent/NI201200019A/es unknown
- 2012-02-05 IL IL217954A patent/IL217954A/en active IP Right Grant
- 2012-02-06 CL CL2012000314A patent/CL2012000314A1/es unknown
- 2012-02-07 EC ECSP12011651 patent/ECSP12011651A/es unknown
-
2013
- 2013-08-14 ZA ZA2013/05992A patent/ZA201305992B/en unknown
Also Published As
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| US9862686B2 (en) | N1-sulfonyl-5-fluoropyrimidinone derivatives | |
| CA2769251C (en) | 5-fluoro-2-oxopyrimidine- 1(2h)-carboxylate derivatives | |
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| CA2769656C (en) | N1-substituted-5-fluoro-2-oxopyrimidinone-1(2h)-carboxamide derivatives | |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request |
Effective date: 20150731 |
|
| MKLA | Lapsed |
Effective date: 20190806 |