CA2769006A1 - Method and apparatus for conducting an assay - Google Patents
Method and apparatus for conducting an assay Download PDFInfo
- Publication number
- CA2769006A1 CA2769006A1 CA2769006A CA2769006A CA2769006A1 CA 2769006 A1 CA2769006 A1 CA 2769006A1 CA 2769006 A CA2769006 A CA 2769006A CA 2769006 A CA2769006 A CA 2769006A CA 2769006 A1 CA2769006 A1 CA 2769006A1
- Authority
- CA
- Canada
- Prior art keywords
- platform
- nucleic acid
- acid strand
- discrete areas
- binding partner
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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Classifications
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- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/00029—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M1/00—Apparatus for enzymology or microbiology
- C12M1/10—Apparatus for enzymology or microbiology rotatably mounted
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- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
- B01L3/5085—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates
- B01L3/50851—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates specially adapted for heating or cooling samples
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- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/5308—Immunoassay; Biospecific binding assay; Materials therefor for analytes not provided for elsewhere, e.g. nucleic acids, uric acid, worms, mites
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- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
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- B01J2219/00603—Making arrays on substantially continuous surfaces
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- B01J2219/0061—The surface being organic
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- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
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- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
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- B01J2219/00603—Making arrays on substantially continuous surfaces
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- B01J2219/00637—Introduction of reactive groups to the surface by coating it with another layer
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- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00718—Type of compounds synthesised
- B01J2219/0072—Organic compounds
- B01J2219/00722—Nucleotides
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- B—PERFORMING OPERATIONS; TRANSPORTING
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- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
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- B01L2300/08—Geometry, shape and general structure
- B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
- B01L2300/0864—Configuration of multiple channels and/or chambers in a single devices comprising only one inlet and multiple receiving wells, e.g. for separation, splitting
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- B—PERFORMING OPERATIONS; TRANSPORTING
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- B01L2400/0409—Moving fluids with specific forces or mechanical means specific forces centrifugal forces
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- G—PHYSICS
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- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N2035/00465—Separating and mixing arrangements
- G01N2035/00495—Centrifuges
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- Immunology (AREA)
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| AU2012200646B2 (en) * | 2012-02-03 | 2014-09-25 | Pyrobett Pte Ltd. | Method and apparatus for conducting an assay |
| DK2809799T3 (en) * | 2012-02-03 | 2017-07-17 | Pyrobett Pte Ltd | Rotatable Nucleic Acid Sequencing Lead Platform |
| US9146248B2 (en) | 2013-03-14 | 2015-09-29 | Intelligent Bio-Systems, Inc. | Apparatus and methods for purging flow cells in nucleic acid sequencing instruments |
| US9591268B2 (en) | 2013-03-15 | 2017-03-07 | Qiagen Waltham, Inc. | Flow cell alignment methods and systems |
| US10222304B2 (en) * | 2013-03-15 | 2019-03-05 | Massachusetts Institute Of Technology | Deposition and imaging of particles on planar substrates |
| US20200330996A1 (en) * | 2016-06-02 | 2020-10-22 | Integrated Nano-Technologies, Inc. | System and method for optimizing heat transfer for target amplification within a diagnostic assay system |
| US11499962B2 (en) | 2017-11-17 | 2022-11-15 | Ultima Genomics, Inc. | Methods and systems for analyte detection and analysis |
| US10344328B2 (en) | 2017-11-17 | 2019-07-09 | Ultima Genomics, Inc. | Methods for biological sample processing and analysis |
| WO2020100039A1 (en) * | 2018-11-13 | 2020-05-22 | National Research Council Of Canada | World-to-chip automated interface for centrifugal microfluidic platforms |
| US10512911B1 (en) | 2018-12-07 | 2019-12-24 | Ultima Genomics, Inc. | Implementing barriers for controlled environments during sample processing and detection |
| US12239980B2 (en) | 2018-12-07 | 2025-03-04 | Ultima Genomics, Inc. | Implementing barriers for controlled environments during sample processing and detection |
| US10852518B1 (en) | 2019-03-14 | 2020-12-01 | Ultima Genomics, Inc. | Methods, devices, and systems for analyte detection and analysis |
| US10900078B2 (en) | 2019-03-14 | 2021-01-26 | Ultima Genomics, Inc. | Methods, devices, and systems for analyte detection and analysis |
| US11118223B2 (en) | 2019-03-14 | 2021-09-14 | Ultima Genomics, Inc. | Methods, devices, and systems for analyte detection and analysis |
| US10830703B1 (en) | 2019-03-14 | 2020-11-10 | Ultima Genomics, Inc. | Methods, devices, and systems for analyte detection and analysis |
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| US4883750A (en) | 1984-12-13 | 1989-11-28 | Applied Biosystems, Inc. | Detection of specific sequences in nucleic acids |
| US4971903A (en) | 1988-03-25 | 1990-11-20 | Edward Hyman | Pyrophosphate-based method and apparatus for sequencing nucleic acids |
| GB9210168D0 (en) | 1992-05-12 | 1992-06-24 | Cemu Bioteknik Ab | Method of sequencing dna |
| US5639428A (en) * | 1994-07-19 | 1997-06-17 | Becton Dickinson And Company | Method and apparatus for fully automated nucleic acid amplification, nucleic acid assay and immunoassay |
| US5750341A (en) | 1995-04-17 | 1998-05-12 | Lynx Therapeutics, Inc. | DNA sequencing by parallel oligonucleotide extensions |
| US6258533B1 (en) * | 1996-11-01 | 2001-07-10 | The University Of Iowa Research Foundation | Iterative and regenerative DNA sequencing method |
| AUPO652997A0 (en) * | 1997-04-30 | 1997-05-29 | Kindconi Pty Limited | Temperature cycling device and method |
| US5922617A (en) * | 1997-11-12 | 1999-07-13 | Functional Genetics, Inc. | Rapid screening assay methods and devices |
| US20020177144A1 (en) * | 1997-12-30 | 2002-11-28 | Jose Remacle | Detection and/or quantification method of a target molecule by a binding with a capture molecule fixed on the surface of a disc |
| GB9828785D0 (en) * | 1998-12-30 | 1999-02-17 | Amersham Pharm Biotech Ab | Sequencing systems |
| US6632655B1 (en) * | 1999-02-23 | 2003-10-14 | Caliper Technologies Corp. | Manipulation of microparticles in microfluidic systems |
| US6884395B2 (en) * | 2000-05-12 | 2005-04-26 | Gyros Ab | Integrated microfluidic disc |
| KR20020063359A (ko) * | 2001-01-27 | 2002-08-03 | 일렉트론 바이오 (주) | 핵산 및 올리거뉴클레오티드의 상보적 이중결합의 특정서열에 특이적으로 반응하는 절단기법을 이용한 핵산 혼성분석 방법 및 장치 |
| US20040234971A1 (en) * | 2001-02-01 | 2004-11-25 | Joany Jackman | Diagnosis of pathogen infections using mass spectral analysis of immune system modulators in post-exposure biological samples |
| WO2003087827A2 (en) * | 2001-04-11 | 2003-10-23 | Burstein Technologies, Inc. | Multi-parameter assays including analysis discs and methods relating thereto |
| AU2002952797A0 (en) * | 2002-11-20 | 2002-12-05 | Bio-Molecular Holdings Pty Limited | Centrifugal device and method using same |
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| US8597882B2 (en) | 2012-02-03 | 2013-12-03 | Pyrobett Pte. Ltd. | Method and apparatus for conducting an assay |
| CN104471077B (zh) * | 2012-05-21 | 2017-05-24 | 富鲁达公司 | 颗粒群的单颗粒分析 |
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| US8921040B2 (en) | 2014-12-30 |
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| EEER | Examination request |
Effective date: 20150728 |
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| FZDE | Discontinued |
Effective date: 20170707 |