CA2768711A1 - Gene expression markers for crohn's disease - Google Patents

Gene expression markers for crohn's disease Download PDF

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Publication number
CA2768711A1
CA2768711A1 CA2768711A CA2768711A CA2768711A1 CA 2768711 A1 CA2768711 A1 CA 2768711A1 CA 2768711 A CA2768711 A CA 2768711A CA 2768711 A CA2768711 A CA 2768711A CA 2768711 A1 CA2768711 A1 CA 2768711A1
Authority
CA
Canada
Prior art keywords
expression
ibd
genes
antibody
subject
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2768711A
Other languages
English (en)
French (fr)
Inventor
Alexander R. Abbas
Hilary Clark
Lauri Diehl
Charles Lees
Colin L. Noble
Jack Satsangi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Genentech Inc
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of CA2768711A1 publication Critical patent/CA2768711A1/en
Abandoned legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Transplantation (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA2768711A 2009-07-20 2010-07-19 Gene expression markers for crohn's disease Abandoned CA2768711A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US22704909P 2009-07-20 2009-07-20
US61/227,049 2009-07-20
US30208410P 2010-02-05 2010-02-05
US61/302,084 2010-02-05
PCT/US2010/042487 WO2011011339A1 (en) 2009-07-20 2010-07-19 Gene expression markers for crohn's disease

Publications (1)

Publication Number Publication Date
CA2768711A1 true CA2768711A1 (en) 2011-01-27

Family

ID=42732741

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2768711A Abandoned CA2768711A1 (en) 2009-07-20 2010-07-19 Gene expression markers for crohn's disease

Country Status (8)

Country Link
US (2) US20110033486A1 (https=)
EP (3) EP2757160A3 (https=)
JP (1) JP2012533322A (https=)
CN (1) CN102639710A (https=)
AU (1) AU2010276392A1 (https=)
CA (1) CA2768711A1 (https=)
SG (1) SG177699A1 (https=)
WO (1) WO2011011339A1 (https=)

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US9580752B2 (en) 2008-12-24 2017-02-28 Cedars-Sinai Medical Center Methods of predicting medically refractive ulcerative colitis (MR-UC) requiring colectomy
WO2014009535A2 (en) * 2012-07-12 2014-01-16 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods for predicting the survival time and treatment responsiveness of a patient suffering from a solid cancer with a signature of at least 7 genes
KR102343212B1 (ko) 2013-03-27 2021-12-23 세다르스-신나이 메디칼 센터 Tl1a 기능 및 관련된 신호전달 경로의 저해에 의한 섬유증 및 염증의 완화 및 반전
CN105209643A (zh) * 2013-05-17 2015-12-30 豪夫迈·罗氏有限公司 用于诊断和治疗炎性肠病的方法
WO2015010108A1 (en) 2013-07-19 2015-01-22 Cedars-Sinai Medical Center Signature of tl1a (tnfsf15) signaling pathway
KR20220065091A (ko) 2014-03-27 2022-05-19 제넨테크, 인크. 염증성 장 질환의 진단 및 치료 방법
EP3137628A4 (en) * 2014-05-02 2018-03-21 Cedars-Sinai Medical Center Methods of predicting medically refractive ulcerative colitis (mruc) requiring colectomy
US11186872B2 (en) 2016-03-17 2021-11-30 Cedars-Sinai Medical Center Methods of diagnosing inflammatory bowel disease through RNASET2
CN107541790B (zh) * 2016-06-24 2021-07-06 上海交通大学 一种糖基化检测的人凝集素/类人凝集素芯片及制备方法
IT201600090052A1 (it) * 2016-09-06 2018-03-06 Univ Degli Studi Padova Peptide per la diagnosi differenziale della Malattia di Crohn
CN106755293B (zh) * 2016-09-23 2020-09-04 宁波大学 一种与肺癌辅助诊断相关的lncRNA标志物及其应用
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CN112041933B (zh) * 2018-03-14 2025-05-13 皇家飞利浦有限公司 使用局部独特特征来解释rna测序数据的转录本表达水平的系统和方法
CN108893488A (zh) * 2018-06-19 2018-11-27 刘志强 一种重组质粒、dna疫苗及其制备方法和应用
JP2022533956A (ja) 2019-05-14 2022-07-27 プロメテウス バイオサイエンシーズ，インク． Ｔｌ１ａ患者を選択する方法、システム、およびデバイス
CN112578122B (zh) * 2019-09-27 2022-08-02 成都中医药大学 检测粪钙卫蛋白含量的试剂在制备畸形精子症筛查试剂盒中的用途
CN116168765B (zh) * 2023-04-25 2023-08-18 山东大学 基于改进strobemer的基因序列生成方法及系统
CN117031004B (zh) * 2023-08-09 2024-10-01 四川省医学科学院·四川省人民医院 一种检测网膜素-1的试剂在制备预测或评估ibs患者生活质量的产品中的应用

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Also Published As

Publication number Publication date
SG177699A1 (en) 2012-02-28
EP2584049A3 (en) 2013-08-28
AU2010276392A1 (en) 2012-03-08
EP2757160A2 (en) 2014-07-23
WO2011011339A1 (en) 2011-01-27
US20110033486A1 (en) 2011-02-10
US20140154275A1 (en) 2014-06-05
EP2584049A2 (en) 2013-04-24
EP2757160A3 (en) 2014-07-30
JP2012533322A (ja) 2012-12-27
CN102639710A (zh) 2012-08-15
EP2456890A1 (en) 2012-05-30
AU2010276392A2 (en) 2012-03-08

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Legal Events

Date Code Title Description
FZDE Discontinued

Effective date: 20160720