CA2768711A1 - Gene expression markers for crohn's disease - Google Patents

Gene expression markers for crohn's disease Download PDF

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Publication number
CA2768711A1
CA2768711A1 CA2768711A CA2768711A CA2768711A1 CA 2768711 A1 CA2768711 A1 CA 2768711A1 CA 2768711 A CA2768711 A CA 2768711A CA 2768711 A CA2768711 A CA 2768711A CA 2768711 A1 CA2768711 A1 CA 2768711A1
Authority
CA
Canada
Prior art keywords
expression
ibd
genes
antibody
subject
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2768711A
Other languages
English (en)
French (fr)
Inventor
Alexander R. Abbas
Hilary Clark
Lauri Diehl
Charles Lees
Colin L. Noble
Jack Satsangi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Genentech Inc
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of CA2768711A1 publication Critical patent/CA2768711A1/en
Abandoned legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/158Expression markers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Transplantation (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA2768711A 2009-07-20 2010-07-19 Gene expression markers for crohn's disease Abandoned CA2768711A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US22704909P 2009-07-20 2009-07-20
US61/227,049 2009-07-20
US30208410P 2010-02-05 2010-02-05
US61/302,084 2010-02-05
PCT/US2010/042487 WO2011011339A1 (en) 2009-07-20 2010-07-19 Gene expression markers for crohn's disease

Publications (1)

Publication Number Publication Date
CA2768711A1 true CA2768711A1 (en) 2011-01-27

Family

ID=42732741

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2768711A Abandoned CA2768711A1 (en) 2009-07-20 2010-07-19 Gene expression markers for crohn's disease

Country Status (8)

Country Link
US (2) US20110033486A1 (enExample)
EP (3) EP2584049A3 (enExample)
JP (1) JP2012533322A (enExample)
CN (1) CN102639710A (enExample)
AU (1) AU2010276392A1 (enExample)
CA (1) CA2768711A1 (enExample)
SG (1) SG177699A1 (enExample)
WO (1) WO2011011339A1 (enExample)

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US20140017711A1 (en) * 2011-03-25 2014-01-16 Cedars-Sinai Medical Center Methods of diagnosing ulcerative colitis and crohn's disease
US11242564B2 (en) * 2012-07-12 2022-02-08 Inserm (Institut National De La Sante Et De La Recherche Medicale) Methods for predicting the survival time and treatment responsiveness of a patient suffering from a solid cancer with a signature of at least 7 genes
EP3639841B1 (en) 2013-03-27 2023-09-06 Cedars-Sinai Medical Center Treating fibrosis by inhibiting tl1a
CN105209643A (zh) * 2013-05-17 2015-12-30 豪夫迈·罗氏有限公司 用于诊断和治疗炎性肠病的方法
EP3022295A4 (en) 2013-07-19 2017-03-01 Cedars-Sinai Medical Center Signature of tl1a (tnfsf15) signaling pathway
MA39804A (fr) * 2014-03-27 2017-02-01 Hoffmann La Roche Méthodes permettant le diagnostic et le traitement d'une maladie inflammatoire de l'intestin
EP3137628A4 (en) * 2014-05-02 2018-03-21 Cedars-Sinai Medical Center Methods of predicting medically refractive ulcerative colitis (mruc) requiring colectomy
JP7082945B2 (ja) 2016-03-17 2022-06-09 シーダーズ―シナイ メディカル センター Rnaset2により炎症性腸疾患を診断する方法
CN107541790B (zh) * 2016-06-24 2021-07-06 上海交通大学 一种糖基化检测的人凝集素/类人凝集素芯片及制备方法
IT201600090052A1 (it) * 2016-09-06 2018-03-06 Univ Degli Studi Padova Peptide per la diagnosi differenziale della Malattia di Crohn
CN106755293B (zh) * 2016-09-23 2020-09-04 宁波大学 一种与肺癌辅助诊断相关的lncRNA标志物及其应用
US10890579B2 (en) 2016-10-06 2021-01-12 The Research Foundation For The State University Of New York Methods and kits for detecting a fusion messenger RNA transcript or a polypeptide encoded by the fusion messenger RNA transcript
US20210005285A1 (en) * 2018-03-14 2021-01-07 Koninklijke Philips N.V. System and method using local unique features to interpret transcript expression levels for rna sequencing data
CN108893488A (zh) * 2018-06-19 2018-11-27 刘志强 一种重组质粒、dna疫苗及其制备方法和应用
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CN112578122B (zh) * 2019-09-27 2022-08-02 成都中医药大学 检测粪钙卫蛋白含量的试剂在制备畸形精子症筛查试剂盒中的用途
CN116168765B (zh) * 2023-04-25 2023-08-18 山东大学 基于改进strobemer的基因序列生成方法及系统
CN117031004B (zh) * 2023-08-09 2024-10-01 四川省医学科学院·四川省人民医院 一种检测网膜素-1的试剂在制备预测或评估ibs患者生活质量的产品中的应用

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Also Published As

Publication number Publication date
EP2757160A2 (en) 2014-07-23
JP2012533322A (ja) 2012-12-27
EP2584049A3 (en) 2013-08-28
CN102639710A (zh) 2012-08-15
SG177699A1 (en) 2012-02-28
EP2584049A2 (en) 2013-04-24
AU2010276392A2 (en) 2012-03-08
US20140154275A1 (en) 2014-06-05
WO2011011339A1 (en) 2011-01-27
US20110033486A1 (en) 2011-02-10
AU2010276392A1 (en) 2012-03-08
EP2757160A3 (en) 2014-07-30
EP2456890A1 (en) 2012-05-30

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Legal Events

Date Code Title Description
FZDE Discontinued

Effective date: 20160720