CA2757659A1 - Biomarkers for monitoring treatment of neuropsychiatric diseases - Google Patents

Biomarkers for monitoring treatment of neuropsychiatric diseases Download PDF

Info

Publication number
CA2757659A1
CA2757659A1 CA2757659A CA2757659A CA2757659A1 CA 2757659 A1 CA2757659 A1 CA 2757659A1 CA 2757659 A CA2757659 A CA 2757659A CA 2757659 A CA2757659 A CA 2757659A CA 2757659 A1 CA2757659 A1 CA 2757659A1
Authority
CA
Canada
Prior art keywords
subject
diagnostic
vagus nerve
nerve stimulation
score
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2757659A
Other languages
English (en)
French (fr)
Inventor
Bo Pi
John Bilello
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ridge Diagnostics Inc
Original Assignee
Ridge Diagnostics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ridge Diagnostics Inc filed Critical Ridge Diagnostics Inc
Publication of CA2757659A1 publication Critical patent/CA2757659A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B40/00ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
    • G16B40/10Signal processing, e.g. from mass spectrometry [MS] or from PCR
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/158Expression markers
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B40/00ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Medical Informatics (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Signal Processing (AREA)
  • Immunology (AREA)
  • Software Systems (AREA)
  • Evolutionary Biology (AREA)
  • Bioethics (AREA)
  • Theoretical Computer Science (AREA)
  • Public Health (AREA)
  • Pathology (AREA)
  • Evolutionary Computation (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Microbiology (AREA)
  • Artificial Intelligence (AREA)
  • Databases & Information Systems (AREA)
  • Data Mining & Analysis (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CA2757659A 2009-04-06 2010-04-06 Biomarkers for monitoring treatment of neuropsychiatric diseases Abandoned CA2757659A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US16698609P 2009-04-06 2009-04-06
US61/166,986 2009-04-06
PCT/US2010/030104 WO2010118035A2 (en) 2009-04-06 2010-04-06 Biomarkers for monitoring treatment of neuropsychiatric diseases

Publications (1)

Publication Number Publication Date
CA2757659A1 true CA2757659A1 (en) 2010-10-14

Family

ID=42936849

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2757659A Abandoned CA2757659A1 (en) 2009-04-06 2010-04-06 Biomarkers for monitoring treatment of neuropsychiatric diseases

Country Status (6)

Country Link
US (1) US20100280562A1 (enExample)
EP (1) EP2417448A4 (enExample)
JP (1) JP2012523009A (enExample)
CN (1) CN102460153A (enExample)
CA (1) CA2757659A1 (enExample)
WO (1) WO2010118035A2 (enExample)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10912712B2 (en) 2004-03-25 2021-02-09 The Feinstein Institutes For Medical Research Treatment of bleeding by non-invasive stimulation
US8868177B2 (en) * 2009-03-20 2014-10-21 ElectroCore, LLC Non-invasive treatment of neurodegenerative diseases
US8158374B1 (en) 2006-09-05 2012-04-17 Ridge Diagnostics, Inc. Quantitative diagnostic methods using multiple parameters
US9662490B2 (en) 2008-03-31 2017-05-30 The Feinstein Institute For Medical Research Methods and systems for reducing inflammation by neuromodulation and administration of an anti-inflammatory drug
CA2740736A1 (en) * 2008-10-15 2010-04-22 Ridge Diagnostics, Inc. Human biomarker hypermapping for depressive disorders
EP2356453A4 (en) 2008-11-18 2012-08-15 Ridge Diagnostics Inc METABOLISM SYNDROME AND HPA AXIS BIOMARKERS FOR HEAVY DEPRESSION
CA2757518A1 (en) * 2009-04-01 2010-10-07 Ridge Diagnostics, Inc. Biomarkers for monitoring treatment of neuropsychiatric diseases
US9211410B2 (en) 2009-05-01 2015-12-15 Setpoint Medical Corporation Extremely low duty-cycle activation of the cholinergic anti-inflammatory pathway to treat chronic inflammation
EP2440284B1 (en) 2009-06-09 2018-09-12 Setpoint Medical Corporation Nerve cuff with pocket for leadless stimulator
US11051744B2 (en) 2009-11-17 2021-07-06 Setpoint Medical Corporation Closed-loop vagus nerve stimulation
US20150241447A1 (en) * 2009-11-17 2015-08-27 Ralph J. ZITNIK Vagus nerve stimulation screening test
WO2011079309A2 (en) 2009-12-23 2011-06-30 Setpoint Medical Corporation Neural stimulation devices and systems for treatment of chronic inflammation
CA2788315A1 (en) * 2010-01-26 2011-08-04 Ridge Diagnostics, Inc. Multiple biomarker panels to stratify disease severity and monitor treatment of depression
WO2012081701A1 (ja) 2010-12-16 2012-06-21 独立行政法人産業技術総合研究所 髄液型糖タンパク質の富化及び分離方法、並びにその方法を用いた中枢神経系疾患用マーカーの探索方法及び中枢神経系疾患用マーカー
US20120238837A1 (en) * 2011-03-16 2012-09-20 Searete Llc, A Limited Liability Corporation Of The State Of Delaware System, devices, and methods for real-time monitoring of cerebrospinal fluid for markers of progressive conditions
US12172017B2 (en) 2011-05-09 2024-12-24 Setpoint Medical Corporation Vagus nerve stimulation to treat neurodegenerative disorders
US9572983B2 (en) 2012-03-26 2017-02-21 Setpoint Medical Corporation Devices and methods for modulation of bone erosion
US8737709B2 (en) * 2012-04-30 2014-05-27 General Electric Company Systems and methods for performing correlation analysis on clinical outcome and characteristics of biological tissue
US11525834B2 (en) 2013-07-11 2022-12-13 University Of North Texas Health Science Center At Fort Worth Blood-based screen for detecting neurological diseases in primary care settings
US11885816B2 (en) 2013-11-26 2024-01-30 University Of North Texas Health Science Center At Forth Worth Personalized medicine approach for treating cognitive loss
WO2016004375A2 (en) * 2014-07-02 2016-01-07 Ridge Diagnostics, Inc. Methods and materials for treating pain and depression
US11154712B2 (en) * 2014-08-28 2021-10-26 Medtronic Ardian Luxembourg S.A.R.L. Methods for assessing efficacy of renal neuromodulation and associated systems and devices
US11311725B2 (en) 2014-10-24 2022-04-26 Setpoint Medical Corporation Systems and methods for stimulating and/or monitoring loci in the brain to treat inflammation and to enhance vagus nerve stimulation
WO2016126807A1 (en) 2015-02-03 2016-08-11 Setpoint Medical Corporation Apparatus and method for reminding, prompting, or alerting a patient with an implanted stimulator
US10596367B2 (en) 2016-01-13 2020-03-24 Setpoint Medical Corporation Systems and methods for establishing a nerve block
WO2017127756A1 (en) 2016-01-20 2017-07-27 Setpoint Medical Corporation Control of vagal stimulation
EP3405255A4 (en) 2016-01-20 2019-10-16 Setpoint Medical Corporation IMPLANTABLE MICROSTIMULATORS AND INDUCTIVE CHARGING SYSTEMS
US11471681B2 (en) 2016-01-20 2022-10-18 Setpoint Medical Corporation Batteryless implantable microstimulators
US10583304B2 (en) 2016-01-25 2020-03-10 Setpoint Medical Corporation Implantable neurostimulator having power control and thermal regulation and methods of use
US11045126B2 (en) 2016-10-28 2021-06-29 Koa Health B.V. System and a method for enabling responsive cognitive behavioral therapy
US11872371B2 (en) 2017-04-20 2024-01-16 The Feinstein Institutes For Medical Research Systems and methods for real-time monitoring of physiological biomarkers through nerve signals and uses thereof
EP3668402B1 (en) 2017-08-14 2024-07-31 Setpoint Medical Corporation Vagus nerve stimulation pre-screening test
KR102633621B1 (ko) 2017-09-01 2024-02-05 벤 바이오사이언시스 코포레이션 진단 및 치료 모니터링용 바이오마커로서의 당펩티드의 식별 및 용도
US12287324B2 (en) 2018-01-18 2025-04-29 University Of North Texas Health Science Center At Fort Worth Companion diagnostics for NSAIDS and donepezil for treating specific subpopulations of patients suffering from Alzheimer's disease
US11260229B2 (en) 2018-09-25 2022-03-01 The Feinstein Institutes For Medical Research Methods and apparatuses for reducing bleeding via coordinated trigeminal and vagal nerve stimulation
EP3952982B1 (en) 2019-04-12 2024-03-27 Setpoint Medical Corporation Vagus nerve stimulation system to treat neurodegenerative disorders
CN111524596A (zh) * 2020-04-07 2020-08-11 上海市精神卫生中心(上海市心理咨询培训中心) 一种判断青少年双相障碍发病风险的方法
US11938324B2 (en) 2020-05-21 2024-03-26 The Feinstein Institutes For Medical Research Systems and methods for vagus nerve stimulation
US12444497B2 (en) 2021-05-17 2025-10-14 Setpoint Medical Corporation Neurostimulation parameter authentication and expiration system for neurostimulation

Family Cites Families (47)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5359681A (en) * 1993-01-11 1994-10-25 University Of Washington Fiber optic sensor and methods and apparatus relating thereto
US5882203A (en) * 1995-05-31 1999-03-16 Correa; Elsa I. Method of detecting depression
US5658802A (en) * 1995-09-07 1997-08-19 Microfab Technologies, Inc. Method and apparatus for making miniaturized diagnostic arrays
US5804453A (en) * 1996-02-09 1998-09-08 Duan-Jun Chen Fiber optic direct-sensing bioprobe using a phase-tracking approach
US20050123938A1 (en) * 1999-01-06 2005-06-09 Chondrogene Limited Method for the detection of osteoarthritis related gene transcripts in blood
US20030032773A1 (en) * 2000-02-24 2003-02-13 Herath Herath Mudiyanselage Athula Chandrasiri Proteins, genes and their use for diagnosis and treatment of bipolar affective disorder (BAD) and unipolar depression
US20040110938A1 (en) * 2000-02-24 2004-06-10 Parekh Rajesh Bhikhu Proteins, genes and their use for diagnosis and treatment of schizophrenia
AU4345001A (en) * 2000-03-09 2001-09-17 Clinical Analysis Corp Medical diagnostic system
US7094595B2 (en) * 2000-10-30 2006-08-22 Sru Biosystems, Inc. Label-free high-throughput optical technique for detecting biomolecular interactions
US6905816B2 (en) * 2000-11-27 2005-06-14 Intelligent Medical Devices, Inc. Clinically intelligent diagnostic devices and methods
ATE458199T1 (de) * 2001-05-04 2010-03-15 Biosite Inc Diagnostische marker der akuten koronaren syndrome und ihre verwendungen
US6710877B2 (en) * 2001-07-23 2004-03-23 Corning Incorporated Apparatus and methods for determining biomolecular interactions
US20050095646A1 (en) * 2001-11-19 2005-05-05 Sherman Michael I. Method of using a non-antibody protein to detect and measure an analyte
US7136518B2 (en) * 2003-04-18 2006-11-14 Medispectra, Inc. Methods and apparatus for displaying diagnostic data
US20040152107A1 (en) * 2002-09-18 2004-08-05 C. Anthony Altar Gene signature of electroshock therapy and methods of use
KR20040032451A (ko) * 2002-10-09 2004-04-17 삼성전자주식회사 생체신호 기반의 건강 관리 기능을 갖는 모바일 기기 및이를 이용한 건강 관리 방법
US7490085B2 (en) * 2002-12-18 2009-02-10 Ge Medical Systems Global Technology Company, Llc Computer-assisted data processing system and method incorporating automated learning
US7706871B2 (en) * 2003-05-06 2010-04-27 Nellcor Puritan Bennett Llc System and method of prediction of response to neurological treatment using the electroencephalogram
AU2004238259B2 (en) * 2003-05-06 2010-02-18 Covidien Lp System and method of assessment of the efficacy of treatment of neurological disorders using the electroencephalogram
US20040228766A1 (en) * 2003-05-14 2004-11-18 Witty Thomas R. Point of care diagnostic platform
US20040228765A1 (en) * 2003-05-14 2004-11-18 Witty Thomas R. Point of care diagnostic platform
US20050084880A1 (en) * 2003-07-11 2005-04-21 Ronald Duman Systems and methods for diagnosing & treating psychological and behavioral conditions
US20070092888A1 (en) * 2003-09-23 2007-04-26 Cornelius Diamond Diagnostic markers of hypertension and methods of use thereof
US20050069936A1 (en) * 2003-09-26 2005-03-31 Cornelius Diamond Diagnostic markers of depression treatment and methods of use thereof
US7394547B2 (en) * 2003-11-06 2008-07-01 Fortebio, Inc. Fiber-optic assay apparatus based on phase-shift interferometry
JP2005312435A (ja) * 2004-03-29 2005-11-10 Kazuhito Rokutan うつ病の評価方法
US20050254065A1 (en) * 2004-05-12 2005-11-17 Stokowski Stanley E Method and apparatus for detecting surface characteristics on a mask blank
EP1766398B1 (en) * 2004-06-24 2011-01-05 GE Healthcare Bio-Sciences AB Method for detecting molecular surface interactions
US20060063199A1 (en) * 2004-09-21 2006-03-23 Elgebaly Salwa A Diagnostic marker
US7445887B2 (en) * 2005-01-07 2008-11-04 Fortebio, Inc. Enzyme activity measurements using bio-layer interferometry
JP2007024822A (ja) * 2005-07-21 2007-02-01 Aska Pharmaceutical Co Ltd 男性の更年期又はうつ病の鑑別方法
CA2626490A1 (en) * 2005-10-18 2007-04-26 Cambridge Enterprise Limited Methods and biomarkers for diagnosing and monitoring psychotic disorders such as schizophrenia
US20070161042A1 (en) * 2006-01-11 2007-07-12 Fortebio, Inc. Methods for characterizing molecular interactions
EP2453236A3 (en) * 2006-02-17 2012-08-22 Atsuo Sekiyama Biological load indicator and method of measuring biological load
US20080015465A1 (en) * 2006-06-15 2008-01-17 Scuderi Gaetano J Methods for diagnosing and treating pain in the spinal cord
US7651836B2 (en) * 2006-08-04 2010-01-26 Hospital Santiago Apóstol Methods for diagnosis and prognostic of psychiatric diseases
US8158374B1 (en) * 2006-09-05 2012-04-17 Ridge Diagnostics, Inc. Quantitative diagnostic methods using multiple parameters
US20080199866A1 (en) * 2006-10-10 2008-08-21 The Board Of Trustees Of The Leland Stanford Junior University Snp detection and other methods for characterizing and treating bipolar disorder and other ailments
WO2008099972A1 (ja) * 2007-02-16 2008-08-21 Shimadzu Corporation 上皮性卵巣癌の組織型識別マーカー、及びそれを用いた組織型に基づく上皮性卵巣癌の罹患の識別法
US20080281531A1 (en) * 2007-03-15 2008-11-13 Kazuhito Rokutan Method for Diagnosing Depression
WO2009114627A2 (en) * 2008-03-12 2009-09-17 Ridge Diagnostics, Inc. Inflammatory biomarkers for monitoring depression disorders
EP2329260A4 (en) * 2008-03-04 2011-08-03 Ridge Diagnostics Inc DIAGNOSIS AND MONITORING OF DEPRESSIVE DISORDERS BASED ON A PLURALITY OF BIOMARKER PANELS
CA2740736A1 (en) * 2008-10-15 2010-04-22 Ridge Diagnostics, Inc. Human biomarker hypermapping for depressive disorders
EP2356453A4 (en) * 2008-11-18 2012-08-15 Ridge Diagnostics Inc METABOLISM SYNDROME AND HPA AXIS BIOMARKERS FOR HEAVY DEPRESSION
CA2757518A1 (en) * 2009-04-01 2010-10-07 Ridge Diagnostics, Inc. Biomarkers for monitoring treatment of neuropsychiatric diseases
CA2788315A1 (en) * 2010-01-26 2011-08-04 Ridge Diagnostics, Inc. Multiple biomarker panels to stratify disease severity and monitor treatment of depression
CN103370624A (zh) * 2010-12-06 2013-10-23 里奇诊断学股份有限公司 监控神经精神疾病治疗的生物标记

Also Published As

Publication number Publication date
US20100280562A1 (en) 2010-11-04
EP2417448A4 (en) 2012-10-24
WO2010118035A2 (en) 2010-10-14
JP2012523009A (ja) 2012-09-27
EP2417448A2 (en) 2012-02-15
WO2010118035A3 (en) 2011-01-13
CN102460153A (zh) 2012-05-16

Similar Documents

Publication Publication Date Title
US20100280562A1 (en) Biomarkers for monitoring treatment of neuropsychiatric diseases
EP2414824B1 (en) Biomarkers for monitoring treatment of neuropsychiatric diseases
JP5663314B2 (ja) 多数のバイオマーカーパネルに基づくうつ障害の診断およびモニタリング
JP5744063B2 (ja) うつ病の疾患重症度を層別化するためおよび処置をモニタリングするための複数のバイオマーカーパネル
US20120178118A1 (en) Biomarkers for monitoring treatment of neuropsychiatric diseases
JP5658571B2 (ja) うつ障害をモニタリングするための炎症バイオマーカー
US20170131295A1 (en) Multiple biomarker panels to stratify disease severity and monitor treatment of depression
JP5540000B2 (ja) うつ病性障害のヒトバイオマーカーハイパーマッピング
CN102301234B (zh) 针对重度抑郁疾病的代谢综合症状及hpa轴生物标志物
US20170161441A1 (en) Methods and materials for treating pain and depression
HK1171081A (en) Biomarkers for monitoring treatment of neuropsychiatric diseases
HK1171807A (en) Biomarkers for monitoring treatment of neuropsychiatric diseases
HK1190789A (en) Biomarkers for monitoring treatment of neuropsychiatric diseases
HK1164379A (en) Human biomarker hypermapping for depressive disorders

Legal Events

Date Code Title Description
EEER Examination request

Effective date: 20150407

FZDE Discontinued

Effective date: 20170406