CA2754826A1 - Live attenuated influenza virus vaccines comprising microrna response elements - Google Patents
Live attenuated influenza virus vaccines comprising microrna response elements Download PDFInfo
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- CA2754826A1 CA2754826A1 CA2754826A CA2754826A CA2754826A1 CA 2754826 A1 CA2754826 A1 CA 2754826A1 CA 2754826 A CA2754826 A CA 2754826A CA 2754826 A CA2754826 A CA 2754826A CA 2754826 A1 CA2754826 A1 CA 2754826A1
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| US15823309P | 2009-03-06 | 2009-03-06 | |
| US61/158,233 | 2009-03-06 | ||
| PCT/US2010/000709 WO2010101663A2 (en) | 2009-03-06 | 2010-03-08 | Live attenuated influenza virus vaccines comprising microrna response elements |
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| CA2754826A1 true CA2754826A1 (en) | 2010-09-10 |
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| JP (1) | JP2012519484A (enExample) |
| CA (1) | CA2754826A1 (enExample) |
| WO (1) | WO2010101663A2 (enExample) |
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| AU2004235396B2 (en) | 2003-04-29 | 2010-11-25 | Sarepta Therapeutics, Inc. | Compositions for enhancing transport and antisense efficacy of nucleic acid analog into cells |
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| US8877206B2 (en) | 2007-03-22 | 2014-11-04 | Pds Biotechnology Corporation | Stimulation of an immune response by cationic lipids |
| US20100016215A1 (en) | 2007-06-29 | 2010-01-21 | Avi Biopharma, Inc. | Compound and method for treating myotonic dystrophy |
| AU2009236306B2 (en) | 2008-04-17 | 2015-04-02 | Pds Biotechnology Corporation | Stimulation of an immune response by enantiomers of cationic lipids |
| US8883995B2 (en) * | 2009-03-06 | 2014-11-11 | Icahn School Of Medicine At Mount Sinai | Live attenuated influenza virus vaccines comprising microRNA response elements |
| US20110269665A1 (en) | 2009-06-26 | 2011-11-03 | Avi Biopharma, Inc. | Compound and method for treating myotonic dystrophy |
| WO2011131193A1 (en) * | 2010-04-24 | 2011-10-27 | Statens Serum Institut | Diagnosing and treating fibrotic diseases using micro-rna 17 |
| PT3351636T (pt) | 2010-05-14 | 2020-09-24 | Univ Oregon Health & Science | Vectores de hcmv e rhcmv recombinantes codificadores de um antigénio heterólogo isolado a partir de um vírus paramyxoviridae e seus usos |
| WO2012051491A1 (en) * | 2010-10-14 | 2012-04-19 | The United States Of America, As Represented By The Secretary National Institutes Of Health | Compositions and methods for controlling neurotropic viral pathogenesis by micro-rna targeting |
| JP6006292B2 (ja) * | 2011-04-08 | 2016-10-12 | インサーム（インスティテュ ナシオナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシェ メディカル）Ｉｎｓｅｒｍ（Ｉｎｓｔｉｔｕｔ Ｎａｔｉｏｎａｌ Ｄｅｌａ Ｓａｎｔｅ Ｅｔ Ｄｅ Ｌａ Ｒｅｃｈｅｒｃｈｅ Ｍｅｄｉｃａｌｅ） | インフルエンザウイルス複製を阻害するための方法および医薬組成物 |
| US9161948B2 (en) | 2011-05-05 | 2015-10-20 | Sarepta Therapeutics, Inc. | Peptide oligonucleotide conjugates |
| ES2667425T3 (es) | 2011-06-10 | 2018-05-10 | Oregon Health & Science University | Glucoproteínas y vectores recombinantes de CMV |
| US20130280215A1 (en) * | 2011-10-18 | 2013-10-24 | Geovax, Inc. | Mva vectors expressing polypeptides and having high level production in certain cell lines |
| EP2859103B1 (en) | 2012-06-06 | 2019-04-17 | Boehringer Ingelheim International GmbH | CELL ENGINEERING USING RNAs |
| US10286064B2 (en) | 2012-06-15 | 2019-05-14 | Pds Biotechnology Corporation | Cationic lipid vaccine compositions and methods of use |
| AU2013317805B2 (en) | 2012-09-21 | 2018-07-26 | Pds Biotechnology Corporation | Improved vaccine compositions and methods of use |
| LT2964769T (lt) | 2013-03-05 | 2018-12-10 | Oregon Health & Science University | Citomegalo viruso vektoriai, leidžiantys kontroliuoti ląstelių nukreipimą į taikinį |
| CA2898130A1 (en) | 2013-03-15 | 2014-09-18 | The Trustees Of The University Of Pennsylvania | Vaccines with biomolecular adjuvants |
| CN104694541A (zh) | 2013-12-09 | 2015-06-10 | 江苏命码生物科技有限公司 | 禽流感病毒miRNA及其鉴定、检测和应用 |
| WO2015195881A1 (en) * | 2014-06-18 | 2015-12-23 | The Regents Of The University Of California | Methods and compositions for inhibiting infection by influenza and viruses |
| NZ728208A (en) | 2014-07-16 | 2018-07-27 | Univ Oregon Health & Science | Human cytomegalovirus comprising exogenous antigens |
| WO2016061200A1 (en) * | 2014-10-14 | 2016-04-21 | Texas Tech University System | Live attenuated viral vaccine created by self-attenuation with species-specific artificial microrna |
| WO2016088380A1 (ja) * | 2014-12-03 | 2016-06-09 | 公益財団法人ヒューマンサイエンス振興財団 | ムンプスウイルスの弱毒化方法、ムンプスウイルス、及び、生ワクチン |
| EA201791806A1 (ru) | 2015-02-10 | 2017-12-29 | Орегон Хелс Энд Сайенс Юниверсити | Способы и композиции, полезные при генерировании неканонических cd8+ т-клеточных ответов |
| US11020417B2 (en) | 2015-06-04 | 2021-06-01 | Sarepta Therapeutics, Inc | Methods and compounds for treatment of lymphocyte-related diseases and conditions |
| US10927151B2 (en) | 2015-06-09 | 2021-02-23 | Sanofi Pasteur Inc. | Methods of optimizing nucleotide sequences encoding engineered influenza proteins |
| US10383935B2 (en) | 2015-09-23 | 2019-08-20 | Regents Of The University Of Minnesota | Methods of making and using live attenuated viruses |
| US10086063B2 (en) * | 2015-09-23 | 2018-10-02 | Regents Of The University Of Minnesota | Methods of making and using live attenuated viruses |
| US11612652B2 (en) | 2015-11-13 | 2023-03-28 | Pds Biotechnology Corporation | Lipids as synthetic vectors to enhance antigen processing and presentation ex-vivo in dendritic cell therapy |
| US10688164B2 (en) * | 2015-11-20 | 2020-06-23 | Oregon Health & Science University | CMV vectors comprising microRNA recognition elements |
| EP3481848B1 (en) * | 2016-07-08 | 2021-02-17 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Genomic sequences encoding for an attenuated mutant zika virus |
| WO2018075591A1 (en) | 2016-10-18 | 2018-04-26 | Oregon Health & Science University | Cytomegalovirus vectors eliciting t cells restricted by major histocompatibility complex e molecules |
| WO2019086463A1 (en) | 2017-10-30 | 2019-05-09 | Baxalta GmbH | Environmentally compatible detergents for inactivation of lipid-enveloped viruses |
| TW201924722A (zh) | 2017-12-05 | 2019-07-01 | 美商Ｐｄｓ生技公司 | 用於刺激第i型干擾素基因之方法及包含陽離子脂質的組合物 |
| JP2021508696A (ja) | 2017-12-22 | 2021-03-11 | コーダ−ジェニックス・インコーポレイテッドＣｏｄａ−Ｇｅｎｉｘ， Ｉｎｃ． | がん処置のためのコドン対脱最適化領域を有する組換え型ウイルス及びその使用法 |
| WO2019172982A1 (en) | 2018-03-08 | 2019-09-12 | Codagenix Inc. | Attenuated flaviviruses |
| KR102831806B1 (ko) | 2018-04-20 | 2025-07-09 | 텍사스 테크 유니버시티 시스템 | 병원체에 대한 자가-약독화된 예방 및 치료 백신 |
| WO2020244605A1 (zh) * | 2019-06-04 | 2020-12-10 | 凌斌 | 重组非结构蛋白1、含此的重组流感病毒及免疫组成物及其用于制备流感病毒疫苗组成物的用途 |
| JP2024535145A (ja) * | 2021-09-03 | 2024-09-27 | バヴァリアン・ノルディック・アクティーゼルスカブ | 改変ワクシニアウイルスアンカラ（ｍｖａ）による細胞傷害性導入遺伝子発現を下方調節するためのマイクロｒｎａの利用 |
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| ATE546528T1 (de) | 2002-11-13 | 2012-03-15 | Univ Jefferson | Zusammensetzungen und verfahren zur diagnose und behandlung von krebs |
| JP2007525175A (ja) * | 2003-04-23 | 2007-09-06 | ウィスコンシン アルムニ リサーチ ファウンデイション | 突然変異した膜タンパク質をその機能性の一部ウイルス |
| US8145436B2 (en) * | 2003-07-15 | 2012-03-27 | The Trustees Of The University Of Pennsylvania | Method and systems for identifying micro-RNA targets and synthesizing novel micro-RNAs and uses of the same |
| US8106180B2 (en) | 2003-08-07 | 2012-01-31 | Whitehead Institute For Biomedical Research | Methods and products for expression of micro RNAs |
| US7279275B2 (en) * | 2003-11-03 | 2007-10-09 | Washington University | Methods and compositions for detection of segmented negative strand RNA viruses |
| WO2006033691A2 (en) * | 2004-07-02 | 2006-03-30 | Niman Henry L | Copy choice recombination and uses thereof |
| US20070213293A1 (en) | 2005-04-08 | 2007-09-13 | Nastech Pharmaceutical Company Inc. | Rnai therapeutic for respiratory virus infection |
| US20070054872A1 (en) * | 2005-08-24 | 2007-03-08 | Mirus Bio Corporation | Regulatable or conditional expression systems |
| US20080045472A1 (en) * | 2006-03-31 | 2008-02-21 | Council Of Scientific And Industrial Research Bharat Biotech | Targets for human micro rnas in avian influenza virus (h5n1) genome |
| US9072701B2 (en) * | 2006-04-21 | 2015-07-07 | St. Jude Children's Research Hospital | Avian influenza viruses, vaccines, compositions, formulations, and methods |
| JP2010514424A (ja) * | 2006-12-22 | 2010-05-06 | ザ ペン ステート リサーチ ファウンデーション | 改変ポリメラーゼおよび弱毒化ウイルスならびにそれらの使用方法 |
| EP2115141A4 (en) | 2007-02-20 | 2010-08-04 | Monsanto Technology Llc | miRNA FROM INVERTEBRATES |
| PL2139515T5 (pl) * | 2007-03-30 | 2024-04-08 | The Research Foundation Of The State University Of New York | Atenuowane wirusy przydatne w szczepionkach |
| US20120115131A1 (en) * | 2007-05-31 | 2012-05-10 | Yale University | Genetic lesion associated with cancer |
| US9090894B2 (en) * | 2007-12-17 | 2015-07-28 | California Institute Of Technology | Modulating immune system development and function through microRNA MIR-146 |
| WO2009111892A1 (en) * | 2008-03-14 | 2009-09-17 | Ottawa Health Research Institute | Microrna mediated oncolytic targeting |
| US8883995B2 (en) * | 2009-03-06 | 2014-11-11 | Icahn School Of Medicine At Mount Sinai | Live attenuated influenza virus vaccines comprising microRNA response elements |
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- 2010-03-08 JP JP2011552950A patent/JP2012519484A/ja active Pending
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- 2010-03-08 CA CA2754826A patent/CA2754826A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
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| EP2403527A4 (en) | 2012-11-14 |
| JP2012519484A (ja) | 2012-08-30 |
| WO2010101663A3 (en) | 2010-10-28 |
| US20120148622A1 (en) | 2012-06-14 |
| WO2010101663A2 (en) | 2010-09-10 |
| US8883995B2 (en) | 2014-11-11 |
| EP2403527A2 (en) | 2012-01-11 |
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