CA2754826A1 - Live attenuated influenza virus vaccines comprising microrna response elements - Google Patents
Live attenuated influenza virus vaccines comprising microrna response elements Download PDFInfo
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- CA2754826A1 CA2754826A1 CA2754826A CA2754826A CA2754826A1 CA 2754826 A1 CA2754826 A1 CA 2754826A1 CA 2754826 A CA2754826 A CA 2754826A CA 2754826 A CA2754826 A CA 2754826A CA 2754826 A1 CA2754826 A1 CA 2754826A1
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| PCT/US2010/000709 WO2010101663A2 (en) | 2009-03-06 | 2010-03-08 | Live attenuated influenza virus vaccines comprising microrna response elements |
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| EP1629105B1 (en) | 2003-04-29 | 2010-09-01 | AVI BioPharma, Inc. | Compositions for enhancing transport and antisense efficacy of nucleic acid analog into cells |
| US8067571B2 (en) | 2005-07-13 | 2011-11-29 | Avi Biopharma, Inc. | Antibacterial antisense oligonucleotide and method |
| US8877206B2 (en) | 2007-03-22 | 2014-11-04 | Pds Biotechnology Corporation | Stimulation of an immune response by cationic lipids |
| US20100016215A1 (en) | 2007-06-29 | 2010-01-21 | Avi Biopharma, Inc. | Compound and method for treating myotonic dystrophy |
| AU2009236306B2 (en) | 2008-04-17 | 2015-04-02 | Pds Biotechnology Corporation | Stimulation of an immune response by enantiomers of cationic lipids |
| WO2010101663A2 (en) * | 2009-03-06 | 2010-09-10 | Mount Sinai School Of Medicine Of New York University | Live attenuated influenza virus vaccines comprising microrna response elements |
| US20110269665A1 (en) | 2009-06-26 | 2011-11-03 | Avi Biopharma, Inc. | Compound and method for treating myotonic dystrophy |
| WO2011131193A1 (en) * | 2010-04-24 | 2011-10-27 | Statens Serum Institut | Diagnosing and treating fibrotic diseases using micro-rna 17 |
| EP3333265B1 (en) | 2010-05-14 | 2020-02-05 | Oregon Health & Science University | Recombinant hcmv and rhcmv vectors encoding a heterologous antigen isolated from hepatitis b virus and uses thereof |
| WO2012051491A1 (en) * | 2010-10-14 | 2012-04-19 | The United States Of America, As Represented By The Secretary National Institutes Of Health | Compositions and methods for controlling neurotropic viral pathogenesis by micro-rna targeting |
| US9168236B2 (en) * | 2011-04-08 | 2015-10-27 | Institut National De La Santé Et De La Recherche Médicale (Inserm) | Methods and pharmaceutical compositions for inhibiting influenza viruses replication |
| US9161948B2 (en) | 2011-05-05 | 2015-10-20 | Sarepta Therapeutics, Inc. | Peptide oligonucleotide conjugates |
| SMT201800284T1 (it) | 2011-06-10 | 2018-07-17 | Univ Oregon Health & Science | Glicoproteine cmv e vettori ricombinanti |
| WO2013059498A1 (en) * | 2011-10-18 | 2013-04-25 | Geovax, Inc. | Mva vectors expressing polypeptides and having high level production in certain cell lines |
| EP3536789A1 (en) * | 2012-06-06 | 2019-09-11 | Boehringer Ingelheim International GmbH | Cell engineering using rnas |
| US10286064B2 (en) * | 2012-06-15 | 2019-05-14 | Pds Biotechnology Corporation | Cationic lipid vaccine compositions and methods of use |
| TWI672149B (zh) | 2012-09-21 | 2019-09-21 | 美商Ｐｄｓ生技公司 | 改良之疫苗組成物及使用方法 |
| SI2964769T1 (sl) | 2013-03-05 | 2018-12-31 | Oregon Health & Sccience University | Citomegalovirusni vektorji, ki omogočajo krmiljenje ciljanja T-celic |
| JP6445523B2 (ja) * | 2013-03-15 | 2018-12-26 | ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア | 生体分子アジュバントを含むワクチン |
| CN104694541A (zh) * | 2013-12-09 | 2015-06-10 | 江苏命码生物科技有限公司 | 禽流感病毒miRNA及其鉴定、检测和应用 |
| WO2015195881A1 (en) * | 2014-06-18 | 2015-12-23 | The Regents Of The University Of California | Methods and compositions for inhibiting infection by influenza and viruses |
| KR102205348B1 (ko) | 2014-07-16 | 2021-01-20 | 오레곤 헬스 앤드 사이언스 유니버시티 | 외인성 항원을 포함하는 인간 시토메갈로바이러스 |
| EP3207127A4 (en) * | 2014-10-14 | 2018-06-06 | Texas Tech University System | Live attenuated viral vaccine created by self-attenuation with species-specific artificial microrna |
| JP6620294B2 (ja) * | 2014-12-03 | 2019-12-18 | 公益財団法人ヒューマンサイエンス振興財団 | ムンプスウイルスの弱毒化方法、ムンプスウイルス、及び、生ワクチン |
| CN114317611A (zh) | 2015-02-10 | 2022-04-12 | 俄勒冈健康与科学大学 | 可用于产生非典型cd8+t细胞应答的方法和组合物 |
| US11020417B2 (en) | 2015-06-04 | 2021-06-01 | Sarepta Therapeutics, Inc | Methods and compounds for treatment of lymphocyte-related diseases and conditions |
| US10927151B2 (en) | 2015-06-09 | 2021-02-23 | Sanofi Pasteur Inc. | Methods of optimizing nucleotide sequences encoding engineered influenza proteins |
| US10383935B2 (en) | 2015-09-23 | 2019-08-20 | Regents Of The University Of Minnesota | Methods of making and using live attenuated viruses |
| US10086063B2 (en) | 2015-09-23 | 2018-10-02 | Regents Of The University Of Minnesota | Methods of making and using live attenuated viruses |
| EP4092112A1 (en) | 2015-11-13 | 2022-11-23 | PDS Biotechnology Corporation | Lipids as synthetic vectors to enhance antigen processing and presentation ex-vivo in dendritic cell therapy |
| AU2016355468B2 (en) * | 2015-11-20 | 2022-12-15 | Oregon Health & Science University | CMV vectors comprising microRNA recognition elements |
| JP7046848B2 (ja) * | 2016-07-08 | 2022-04-04 | アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル | 弱毒化突然変異体ジカウイルスをコードするゲノム配列 |
| CN110036112B (zh) | 2016-10-18 | 2024-05-10 | 俄勒冈健康与科学大学 | 引发受主要组织相容性复合体e分子限制的t细胞的巨细胞病毒载体 |
| JP7432506B2 (ja) | 2017-10-30 | 2024-02-16 | 武田薬品工業株式会社 | 脂質エンベロープウイルスを不活化するための環境適合性の界面活性剤 |
| AU2018378588A1 (en) | 2017-12-05 | 2020-06-25 | Pds Biotechnology Corporation | Methods and compositions comprising cationic lipids for stimulating type 1 interferon genes |
| US12178869B2 (en) | 2017-12-22 | 2024-12-31 | Codagenix Inc. | Recombinant virus with codon-pair deoptimized region and uses thereof for the treatment of cancer |
| RU2020132280A (ru) | 2018-03-08 | 2022-04-11 | Кодадженикс Инк. | Аттенуированные флавивирусы |
| WO2019204571A1 (en) | 2018-04-20 | 2019-10-24 | Texas Tech University System | Self-attenuated prophylactic and therapeutic vaccines against pathogens |
| WO2020244605A1 (zh) * | 2019-06-04 | 2020-12-10 | 凌斌 | 重组非结构蛋白1、含此的重组流感病毒及免疫组成物及其用于制备流感病毒疫苗组成物的用途 |
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| JP4939055B2 (ja) | 2002-11-13 | 2012-05-23 | トマス ジェファソン ユニバーシティ | 癌の診断および治療のための組成物および方法 |
| NZ542935A (en) * | 2003-04-23 | 2008-08-29 | Wisconsin Alumni Res Found | Recombinant influenza viruses holding a mutation in a transmembrane protein gene |
| US8145436B2 (en) * | 2003-07-15 | 2012-03-27 | The Trustees Of The University Of Pennsylvania | Method and systems for identifying micro-RNA targets and synthesizing novel micro-RNAs and uses of the same |
| US8106180B2 (en) | 2003-08-07 | 2012-01-31 | Whitehead Institute For Biomedical Research | Methods and products for expression of micro RNAs |
| US7279275B2 (en) | 2003-11-03 | 2007-10-09 | Washington University | Methods and compositions for detection of segmented negative strand RNA viruses |
| AU2005287395A1 (en) | 2004-07-02 | 2006-03-30 | Henry L. Niman | Copy choice recombination and uses thereof |
| US20070213293A1 (en) | 2005-04-08 | 2007-09-13 | Nastech Pharmaceutical Company Inc. | Rnai therapeutic for respiratory virus infection |
| US20070054872A1 (en) * | 2005-08-24 | 2007-03-08 | Mirus Bio Corporation | Regulatable or conditional expression systems |
| US20080045472A1 (en) * | 2006-03-31 | 2008-02-21 | Council Of Scientific And Industrial Research Bharat Biotech | Targets for human micro rnas in avian influenza virus (h5n1) genome |
| US9072701B2 (en) | 2006-04-21 | 2015-07-07 | St. Jude Children's Research Hospital | Avian influenza viruses, vaccines, compositions, formulations, and methods |
| WO2008140622A2 (en) * | 2006-12-22 | 2008-11-20 | The Penn State Research Foundation | Modified polymerases and attenuated viruses and methods of use thereof |
| CN101646769A (zh) | 2007-02-20 | 2010-02-10 | 孟山都技术公司 | 无脊椎动物微rna |
| CN103476425B (zh) * | 2007-03-30 | 2015-07-15 | 纽约州州立大学研究基金会 | 用于疫苗的减毒病毒 |
| EP2527472B1 (en) * | 2007-05-31 | 2016-09-28 | Yale University | A genetic lesion associated with cancer |
| WO2009079592A2 (en) * | 2007-12-17 | 2009-06-25 | California Institute Of Technology | Modulating immune system development and function through microrna mir-146 |
| WO2009111892A1 (en) * | 2008-03-14 | 2009-09-17 | Ottawa Health Research Institute | Microrna mediated oncolytic targeting |
| WO2010101663A2 (en) * | 2009-03-06 | 2010-09-10 | Mount Sinai School Of Medicine Of New York University | Live attenuated influenza virus vaccines comprising microrna response elements |
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- 2010-03-08 EP EP10749069A patent/EP2403527A4/en not_active Withdrawn
- 2010-03-08 JP JP2011552950A patent/JP2012519484A/ja active Pending
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| EP2403527A4 (en) | 2012-11-14 |
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| US8883995B2 (en) | 2014-11-11 |
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| US20120148622A1 (en) | 2012-06-14 |
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