CA2724322C - Diagnosis of melanoma and solar lentigo by nucleic acid analysis - Google Patents

Diagnosis of melanoma and solar lentigo by nucleic acid analysis Download PDF

Info

Publication number
CA2724322C
CA2724322C CA2724322A CA2724322A CA2724322C CA 2724322 C CA2724322 C CA 2724322C CA 2724322 A CA2724322 A CA 2724322A CA 2724322 A CA2724322 A CA 2724322A CA 2724322 C CA2724322 C CA 2724322C
Authority
CA
Canada
Prior art keywords
melanoma
skin
nucleic acid
protein
sample
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA2724322A
Other languages
English (en)
French (fr)
Other versions
CA2724322A1 (en
Inventor
Sherman H. Chang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dermtech Inc
Original Assignee
Dermtech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dermtech Inc filed Critical Dermtech Inc
Publication of CA2724322A1 publication Critical patent/CA2724322A1/en
Application granted granted Critical
Publication of CA2724322C publication Critical patent/CA2724322C/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B35/00—ICT specially adapted for in silico combinatorial libraries of nucleic acids, proteins or peptides
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16C—COMPUTATIONAL CHEMISTRY; CHEMOINFORMATICS; COMPUTATIONAL MATERIALS SCIENCE
    • G16C20/00—Chemoinformatics, i.e. ICT specially adapted for the handling of physicochemical or structural data of chemical particles, elements, compounds or mixtures
    • G16C20/60—In silico combinatorial chemistry
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/112—Disease subtyping, staging or classification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/16—Primer sets for multiplex assays
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/178—Oligonucleotides characterized by their use miRNA, siRNA or ncRNA

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physics & Mathematics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Pathology (AREA)
  • Theoretical Computer Science (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Computing Systems (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Library & Information Science (AREA)
  • Evolutionary Biology (AREA)
  • Medical Informatics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CA2724322A 2008-05-14 2009-05-14 Diagnosis of melanoma and solar lentigo by nucleic acid analysis Active CA2724322C (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US12773108P 2008-05-14 2008-05-14
US61/127,731 2008-05-14
US5398808P 2008-05-16 2008-05-16
US61/053,988 2008-05-16
US5814908P 2008-06-02 2008-06-02
US61/058,149 2008-06-02
PCT/US2009/044035 WO2009140550A2 (en) 2008-05-14 2009-05-14 Diagnosis of melanoma and solar lentigo by nucleic acid analysis

Publications (2)

Publication Number Publication Date
CA2724322A1 CA2724322A1 (en) 2009-11-19
CA2724322C true CA2724322C (en) 2019-07-16

Family

ID=41319348

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2724322A Active CA2724322C (en) 2008-05-14 2009-05-14 Diagnosis of melanoma and solar lentigo by nucleic acid analysis

Country Status (8)

Country Link
US (8) US20110160080A1 (https=)
EP (2) EP2626437A3 (https=)
JP (1) JP2011520451A (https=)
CN (1) CN102089444A (https=)
AU (1) AU2009246180B2 (https=)
BR (1) BRPI0913578A2 (https=)
CA (1) CA2724322C (https=)
WO (1) WO2009140550A2 (https=)

Families Citing this family (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100197518A1 (en) 2007-05-01 2010-08-05 Huichun Xu Methods for Diagnosing Ischemia
AU2008247502A1 (en) * 2007-05-04 2008-11-13 Dermtech International Diagnosis of melanoma by nucleic acid analysis
BRPI0913578A2 (pt) 2008-05-14 2017-06-06 Dermtech Int diagnose de melanoma e lentigo solar por análise de ácido nucléico
EP2593566B1 (en) 2010-07-14 2018-01-24 The Regents of The University of California Biomarkers for diagnosis of transient ischemic attacks
US20120065087A1 (en) 2010-07-15 2012-03-15 Regents Of The University Of California Biomarkers for diagnosis of stroke and its causes
US20120316076A1 (en) 2011-03-04 2012-12-13 The Regents Of The University Of California Biomarkers for the diagnosis of lacunar stroke
EP2691539B1 (en) 2011-03-31 2018-04-25 The Procter and Gamble Company Methods for identifying and evaluating skin-active agents effective for treating dandruff
EP2699222B1 (fr) * 2011-04-22 2019-02-06 L'Oréal Signature moléculaire des taches pigmentaires cutanées, associée à l'organisation de la matrice extracellulaire
FR2974371B1 (fr) * 2011-04-22 2016-10-28 Oreal Signature moleculaire des taches pigmentaires cutanees, associee a la famille des proteoglycanes et glycoproteines extracellulaires
FR2974373B1 (fr) * 2011-04-22 2016-09-02 Oreal Signature moleculaire des taches pigmentaires cutanees, associee a la matrice extracellulaire
FR2974370B1 (fr) * 2011-04-22 2016-09-02 Oreal Signature moleculaire des taches pigmentaires cutanees, associee a la voie de signalisation tgf-beta - smad
FR2974372B1 (fr) * 2011-04-22 2016-09-02 Oreal Signature moleculaire des taches pigmentaires cutanees, associee au remodelage de la matrice extracellulaire
US20150307940A1 (en) * 2011-04-22 2015-10-29 L'oreal Molecular signature of cutaneous pigmentary spots, associated with the extracellular matrix
US9410204B2 (en) 2012-01-07 2016-08-09 The Regents Of The University Of California Biomarkers for diagnosing ischemia
JP2015512261A (ja) * 2012-03-30 2015-04-27 ザ プロクター アンド ギャンブルカンパニー 色素沈着過剰状態の遺伝子発現シグネチャーを生成する方法
US9920357B2 (en) 2012-06-06 2018-03-20 The Procter & Gamble Company Systems and methods for identifying cosmetic agents for hair/scalp care compositions
AU2013277971B2 (en) * 2012-06-22 2018-11-15 Htg Molecular Diagnostics, Inc. Molecular malignancy in melanocytic lesions
KR102017562B1 (ko) * 2013-03-13 2019-09-03 (주)아모레퍼시픽 미백 효능 물질의 스크리닝 방법
WO2014151026A1 (en) * 2013-03-15 2014-09-25 Myriad Genetics, Inc. Genes and gene signatures for diagnosis and treatment of melanoma
US20150005184A1 (en) * 2013-06-28 2015-01-01 Dermtech International Diagnosis of melanoma by nucleic acid analysis
FR3015525B1 (fr) * 2013-12-20 2017-06-09 Oreal Biomarqueur rnase 7 du lentigo actinique
FR3015524B1 (fr) * 2013-12-20 2016-06-03 Oreal Signature moleculaire du lentigo actinique specifique des peaux asiatiques
FR3015523B1 (fr) * 2013-12-20 2020-05-29 L'oreal Signature moleculaire du lentigo actinique
FR3015526B1 (fr) * 2013-12-20 2017-02-17 Oreal Biomarqueur npy1r du lentigo actinique
US20220162682A1 (en) * 2020-11-24 2022-05-26 Dermtech, Inc. Assessment of mutation burden in skin
WO2022221326A1 (en) * 2021-04-13 2022-10-20 Dermtech, Inc. Gene classifiers and uses thereof
WO2019161126A1 (en) 2018-02-14 2019-08-22 Dermtech, Inc. Novel gene classifiers and uses thereof in non-melanoma skin cancers
WO2016003810A1 (en) 2014-07-02 2016-01-07 Myriad Genetics, Inc. Genes and gene signatures for diagnosis and treatment of melanoma
JPWO2016152352A1 (ja) * 2015-03-20 2018-01-11 国立大学法人名古屋大学 メラノーマ特異的バイオマーカー及びその利用
US10709428B2 (en) 2015-05-01 2020-07-14 Dermtech, Inc. Non-invasive skin collection system
EP3433615A1 (en) * 2016-03-21 2019-01-30 Institut National de la Sante et de la Recherche Medicale (INSERM) Methods for diagnosis and treatment of solar lentigo
EP3372693B1 (en) 2016-07-08 2020-02-12 Kao Corporation Method for preparing nucleic acid sample
CA3099275A1 (en) 2018-05-09 2019-11-14 Dermtech, Inc. Novel gene classifiers and uses thereof in autoimmune diseases
WO2020198229A1 (en) 2019-03-26 2020-10-01 Dermtech, Inc. Novel gene classifiers and uses thereof in skin cancers
CA3136108A1 (en) * 2019-04-05 2020-10-08 Dermtech, Inc. Novel gene classifiers for use in monitoring uv damage
EP3883149A1 (en) * 2020-03-20 2021-09-22 Volkswagen Ag Method, apparatus and computer program for predicting a future quality of service of a wireless communication link
EP4194565A4 (en) * 2020-08-10 2024-05-22 Cutis Biomedical Research Center Minimally invasive kit for diagnosing skin condition, comprising microneedle patch
USD988399S1 (en) 2021-02-16 2023-06-06 Dermtech, Inc. Dermatology report document
USD966300S1 (en) 2021-02-16 2022-10-11 Dermtech, Inc. Computer display panel with a graphical user interface for a dermatology report
USD966299S1 (en) 2021-02-16 2022-10-11 Dermtech, Inc. Computer display panel with a graphical user interface for a dermatology report
USD989861S1 (en) 2021-02-16 2023-06-20 Dermtech, Inc. Dermatology report document
US20250075275A1 (en) * 2021-08-05 2025-03-06 The Regents Of The University Of California Gene/protein expression guided melanoma surgery
FR3135992A1 (fr) * 2022-05-25 2023-12-01 L'oreal Signature moléculaire du lentigo actinique associée à la gestion des vésicules
USD1061554S1 (en) 2022-09-09 2025-02-11 Dermtech, Llc Computer display panel with a graphical user interface for a dermatology report
GB202302959D0 (en) 2023-02-28 2023-04-12 Mitra Bio Ltd A method for determining a stage of an epigenetic property of an epidermis
WO2024192031A1 (en) * 2023-03-12 2024-09-19 Novelna Inc. Melanoma detection proteins and methods of use thereof

Family Cites Families (254)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3441430A (en) 1964-11-19 1969-04-29 Minnesota Mining & Mfg Adhesives and adhesive tapes
US4122947A (en) 1978-01-27 1978-10-31 Falla Marjorie B Pre-packaged patient identification kit
JPS567007A (en) 1979-06-29 1981-01-24 Toshiba Corp Coating film thickness measuring apparatus
GB2061598B (en) 1979-10-15 1983-03-02 Chloride Silent Power Ltd Filling sodium-sulphur cells
US4458066A (en) 1980-02-29 1984-07-03 University Patents, Inc. Process for preparing polynucleotides
JPS57156456A (en) 1981-03-24 1982-09-27 Shizuoka Daigaku Preparation of 1,5,5-trimethyl-3-amino-4-cyanocyclohexa-1,3- diene and its derivative
US4388432A (en) 1981-12-15 1983-06-14 Permacel Repulpable acrylic acid based pressure-sensitive adhesive
US4537776A (en) 1983-06-21 1985-08-27 The Procter & Gamble Company Penetrating topical pharmaceutical compositions containing N-(2-hydroxyethyl) pyrrolidone
SE8404895L (sv) 1984-10-01 1986-03-17 Torkel Ingemar Fischer Medel for en overkenslighetstest
US4851510A (en) 1984-11-30 1989-07-25 Wadley Technologies, Inc. Monoclonal antibodies to novel melanoma-associated antigens
US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US4777964A (en) 1986-01-02 1988-10-18 David Briggs System for obtaining blood samples and submitting for testing of aids
US5460939A (en) 1986-04-18 1995-10-24 Advanced Tissue Sciences, Inc. Temporary living skin replacement
US4971800A (en) 1988-07-08 1990-11-20 The Regents Of The University Of California Method and compositions for enhancing the cutaneous penetration of pharmacologically active agents
US5493009A (en) 1989-11-14 1996-02-20 New York Medical College Antiidiotypic monoclonal antibodies MK2-23 anti-melanomal antibody 763.74
DE69121791T2 (de) 1990-06-08 1997-01-23 Behringwerke Ag Verfahren zur quantitativen Bestimmung von DNS-Sequenzen
US6033854A (en) 1991-12-16 2000-03-07 Biotronics Corporation Quantitative PCR using blocking oligonucleotides
US5583032A (en) 1992-10-21 1996-12-10 The Cleveland Clinic Foundation And National Institutes Of Health Method of cleaving specific strands of RNA
US5753612A (en) 1992-10-27 1998-05-19 Yissum Research Development Co. Of The Hebrew University Of Jerusalem Pharmaceutical composition and method for inhibiting hair growth by administration of activin or activin agonists
US5654286A (en) 1993-05-12 1997-08-05 Hostetler; Karl Y. Nucleotides for topical treatment of psoriasis, and methods for using same
KR960703956A (ko) 1993-07-08 1996-08-31 로버트 지. 반 슌넨베르그 아크릴릭-포화 고무 하이브리드 감압 접착제
WO1995006137A1 (en) 1993-08-27 1995-03-02 Australian Red Cross Society Detection of genes
US5843657A (en) 1994-03-01 1998-12-01 The United States Of America As Represented By The Department Of Health And Human Services Isolation of cellular material under microscopic visualization
US5989815A (en) 1994-03-18 1999-11-23 University Of Utah Research Foundation Methods for detecting predisposition to cancer at the MTS gene
US5962477A (en) 1994-04-12 1999-10-05 Adolor Corporation Screening methods for cytokine inhibitors
US5807522A (en) 1994-06-17 1998-09-15 The Board Of Trustees Of The Leland Stanford Junior University Methods for fabricating microarrays of biological samples
US7625697B2 (en) 1994-06-17 2009-12-01 The Board Of Trustees Of The Leland Stanford Junior University Methods for constructing subarrays and subarrays made thereby
JPH0852142A (ja) 1994-07-01 1996-02-27 Medical Biopsy Inc 試料保持手段を備えた生検針組立体及びその使用方法
IT1278052B1 (it) 1995-03-14 1997-11-17 Mendes Srl Uso delle immunoglobuline della classe g, in particolare delle immunoglobuline per uso endovenoso o per uso intramuscolare, per
US5750341A (en) 1995-04-17 1998-05-12 Lynx Therapeutics, Inc. DNA sequencing by parallel oligonucleotide extensions
US6852487B1 (en) 1996-02-09 2005-02-08 Cornell Research Foundation, Inc. Detection of nucleic acid sequence differences using the ligase detection reaction with addressable arrays
US6312909B1 (en) 1996-03-29 2001-11-06 Millennium Pharmaceuticals, Inc. Compositions and methods for the diagnosis prevention and treatment of tumor progression
US6054277A (en) 1996-05-08 2000-04-25 Regents Of The University Of Minnesota Integrated microchip genetic testing system
US5811239A (en) 1996-05-13 1998-09-22 Frayne Consultants Method for single base-pair DNA sequence variation detection
EP1736554B1 (en) 1996-05-29 2013-10-09 Cornell Research Foundation, Inc. Detection of nucleic acid sequence differences using coupled ligase detection and polymerase chain reactions
US6017704A (en) 1996-06-03 2000-01-25 The Johns Hopkins University School Of Medicine Method of detection of methylated nucleic acid using agents which modify unmethylated cytosine and distinguishing modified methylated and non-methylated nucleic acids
US5786146A (en) 1996-06-03 1998-07-28 The Johns Hopkins University School Of Medicine Method of detection of methylated nucleic acid using agents which modify unmethylated cytosine and distinguishing modified methylated and non-methylated nucleic acids
US5858683A (en) 1996-08-30 1999-01-12 Matritech, Inc. Methods and compositions for the detection of cervical cancer
US5921396A (en) 1997-01-21 1999-07-13 Brown, Jr.; Jacob T. Specimen collection kit for mailing and method of using same
US6056859A (en) 1997-02-12 2000-05-02 Lockheed Martin Energy Research Corporation Method and apparatus for staining immobilized nucleic acids
DE19733014A1 (de) 1997-07-31 1999-02-04 Beiersdorf Ag Selbstklebeband
US6551799B2 (en) 1999-12-07 2003-04-22 Genentech, Inc. Interleukin-22 polypeptides, nucleic acids encoding the same and methods for the treatment of pancreatic disorders
US20020006913A1 (en) 1997-11-04 2002-01-17 Von Borstel Reid W. Antimutagenic compositions for treatment and prevention of photodamage to skin
US6054276A (en) 1998-02-23 2000-04-25 Macevicz; Stephen C. DNA restriction site mapping
US6106732A (en) 1998-04-16 2000-08-22 Binax Services, Inc. Integral blood plasma or serum isolation, metering and transport device
US6891022B1 (en) 1998-04-23 2005-05-10 Genentech, Inc. NSP molecules
JP3813818B2 (ja) 1998-05-01 2006-08-23 アリゾナ ボード オブ リージェンツ オリゴヌクレオチドおよびｄｎａ分子のヌクレオチド配列の決定方法
US6780591B2 (en) 1998-05-01 2004-08-24 Arizona Board Of Regents Method of determining the nucleotide sequence of oligonucleotides and DNA molecules
US6787308B2 (en) 1998-07-30 2004-09-07 Solexa Ltd. Arrayed biomolecules and their use in sequencing
ATE491462T1 (de) 1998-08-18 2011-01-15 Dermtech Int Methode zum nachweis biologischer faktoren in der epidermis
KR100326937B1 (ko) 1998-09-23 2002-03-13 정연보 접착성 쉬트로 사람의 표피 ｄｎａ 샘플을 획득하는 방법
US6176836B1 (en) 1998-09-25 2001-01-23 David Trudil Biological sample collection kit
US6203987B1 (en) 1998-10-27 2001-03-20 Rosetta Inpharmatics, Inc. Methods for using co-regulated genesets to enhance detection and classification of gene expression patterns
US7700324B1 (en) 1998-11-03 2010-04-20 The Johns Hopkins University School Of Medicine Methylated CpG island amplification (MCA)
AU1853600A (en) 1999-01-06 2000-07-24 Choong-Chin Liew Method for the detection of gene transcripts in blood and uses thereof
US7094533B1 (en) 1999-01-21 2006-08-22 Board Of Regents Of The University Of Nebraska Therapeutic and diagnostic applications of prostatic acid phosphatase in prostate cancer
US6274362B1 (en) 1999-02-04 2001-08-14 Millennium Pharmaceuticals, Inc. RGS-containing molecules and uses thereof
US6982089B2 (en) 1999-02-24 2006-01-03 Tact Ip, Llc Cytokine antagonists for neurological and neuropsychiatric disorders
US6331393B1 (en) 1999-05-14 2001-12-18 University Of Southern California Process for high-throughput DNA methylation analysis
US6180349B1 (en) 1999-05-18 2001-01-30 The Regents Of The University Of California Quantitative PCR method to enumerate DNA copy number
US6569624B1 (en) 1999-08-12 2003-05-27 Wisconsin Alumni Research Foundation Identification of genetic markers of biological age and metabolism
AUPQ265899A0 (en) 1999-09-03 1999-09-30 Genetic Solutions Pty Ltd Sampling system
AU7987800A (en) 1999-09-29 2001-04-30 Lifespan Biosciences, Inc. Anti-aging nucleic acid and protein targets
US6447463B1 (en) 1999-11-10 2002-09-10 Piotr Borkowski Highly sensitive, practical, widely available diagnostic kit for fungal skin infections
US6726971B1 (en) 1999-12-13 2004-04-27 Tyco Adhesives Lp Thermally stable clear polyurethane adhesive tape
IL133976A (en) 2000-01-11 2006-09-05 Dermipsor Ltd Agents for the treatment of skin disorders
US7611869B2 (en) 2000-02-07 2009-11-03 Illumina, Inc. Multiplexed methylation detection methods
JP2001228449A (ja) * 2000-02-14 2001-08-24 Hamamatsu Photonics Kk レーザ集光装置及びレーザ加工装置
US20020037538A1 (en) 2000-05-09 2002-03-28 Trepicchio William L. Compositions, kits, and methods for identification, assessment, prevention, and therapy of psoriasis
EP1176200A3 (de) 2000-06-20 2005-01-12 Switch Biotech Aktiengesellschaft Verwendung von Polypeptiden oder diese kodierende Nukleinsäuren zur Diagnose oder Behandlung von Hauterkrankung oder Wundheilung sowie ihre Verwendung zur Indentifizierung von pharmakologisch aktiven Substanzen
US7105292B2 (en) 2000-09-08 2006-09-12 New York University Screening methods used to identify compounds that modulate a response of a cell to ultraviolet radiation exposure
US20020165192A1 (en) 2000-09-19 2002-11-07 Kerr William G. Control of NK cell function and survival by modulation of ship activity
US20030017573A1 (en) * 2000-10-04 2003-01-23 Board Of Regents, The University Of Texas System Polymerase kappa compositions and methods thereof
DE10100121A1 (de) 2001-01-03 2002-08-01 Henkel Kgaa Verfahren zur Bestimmung des Hautstreß oder der Hautalterung in vitro
US20020132274A1 (en) 2001-01-17 2002-09-19 Nevalainen Marja T. Diagnostic and monitorings methods for cancer
WO2002098370A2 (en) 2001-03-02 2002-12-12 Medimmune, Inc. Methods of administering/dosing cd2 antagonists for the prevention and treatment of autoimmune disorders or inflammatory disorders
US6642298B2 (en) 2001-03-16 2003-11-04 National Starch And Chemical Investment Holding Corporation Rubber-acrylic adhesive formulation
US6905827B2 (en) 2001-06-08 2005-06-14 Expression Diagnostics, Inc. Methods and compositions for diagnosing or monitoring auto immune and chronic inflammatory diseases
DE10130800B4 (de) 2001-06-22 2005-06-23 Epigenomics Ag Verfahren zum Nachweis von Cytosin-Methylierung mit hoher Sensitivität
AU2002346008A1 (en) 2001-06-28 2003-03-03 Dermtech International Method for detection of melanoma
US6749792B2 (en) 2001-07-09 2004-06-15 Lifescan, Inc. Micro-needles and methods of manufacture and use thereof
JP2003029201A (ja) 2001-07-11 2003-01-29 Canon Inc 画像投射装置及び画像補正方法
US20030133936A1 (en) 2001-07-12 2003-07-17 Byrne Michael Chapman CD25markers and uses thereof
US7229774B2 (en) * 2001-08-02 2007-06-12 Regents Of The University Of Michigan Expression profile of prostate cancer
US7247426B2 (en) * 2001-08-02 2007-07-24 Agilent Technologies, Inc. Classifying cancers
US6857262B2 (en) 2001-08-16 2005-02-22 Spx Corporation Catalytic converter function detection
JPWO2003032259A1 (ja) * 2001-09-27 2005-01-27 富士通株式会社 ネットワークを介したコンテンツ・データの効率的なダウンロード
CN1612936A (zh) 2001-11-09 2005-05-04 苏尔斯精细医药公司 利用基因表达分布图识别、监控和治疗疾病以及鉴定生物学状态
US6692032B2 (en) * 2001-11-28 2004-02-17 Melanie Ann Christy Mole monitoring system
US20030113906A1 (en) 2001-12-14 2003-06-19 Sangha Jangbir S. Method and apparatus for DNA collection
US7921999B1 (en) 2001-12-20 2011-04-12 Watson Laboratories, Inc. Peelable pouch for transdermal patch and method for packaging
US20090082265A1 (en) 2002-01-04 2009-03-26 Myriad Genetics, Incorporated Compositions and methods for treating diseases
US7396871B2 (en) 2002-01-14 2008-07-08 Eastman Chemical Comapny Rubber modified acrylic and/or vinyl hybrid resins
EP1470254A2 (en) 2002-01-30 2004-10-27 Epigenomics AG Method for the analysis of cytosine methylation patterns
US20030167556A1 (en) 2002-03-05 2003-09-11 Consumers Choice Systems, Inc. Methods and devices for transdermal delivery of anti-aging compounds for treatment and prevention of facial or neck skin aging
US20030224422A1 (en) 2002-04-08 2003-12-04 St. Jude Children's Research Hospital, Inc. Pre-and post therapy gene expression profiling to identify drug targets
WO2004046098A2 (en) 2002-05-16 2004-06-03 Vanderbilt University Method for predicting autoimmune diseases
US7217853B2 (en) 2002-05-24 2007-05-15 Corium International, Inc. Composition for cushions, wound dressings and other skin-contacting products
US7267951B2 (en) 2002-06-05 2007-09-11 Sloan-Kettering Institute For Cancer Research Method for evaluating a tissue or biopsy sample to determine if the sample is early-stage melanoma
AU2003302146B2 (en) 2002-06-26 2008-06-26 Cold Spring Harbor Laboratory Methods and compositions for determining methylation profiles
US20080260744A1 (en) 2002-09-09 2008-10-23 Omeros Corporation G protein coupled receptors and uses thereof
AU2003267097B2 (en) 2002-09-11 2009-09-17 Genentech, Inc. Novel composition and methods for the treatment of psoriasis
EP1572116A4 (en) 2002-11-26 2007-12-12 Genentech Inc COMPOSITIONS AND METHODS FOR THE TREATMENT OF IMMUNE DISEASES
US20070077553A1 (en) 2003-10-30 2007-04-05 Rosetta Genomics Bioinformatically detectable group of novel vaccinia regulatory genes and uses thereof
US20040191782A1 (en) 2003-03-31 2004-09-30 Yixin Wang Colorectal cancer prognostics
US7640114B2 (en) 2003-05-21 2009-12-29 The Wistar Institute Of Anatomy & Biology Method of diagnosis of cancer based on gene expression profiles in cells
EP1639090A4 (en) 2003-06-09 2008-04-16 Univ Michigan COMPOSITIONS AND METHODS OF TREATMENT AND DIAGNOSIS OF CANCER
WO2005012578A1 (en) 2003-07-31 2005-02-10 Sequenom, Inc. Methods for high level multiplexed polymerase chain reactions and homogeneous mass extension reactions for genotyping of polymorphisms
EP1510577A1 (en) 2003-08-29 2005-03-02 Qiagen GmbH Method for magnetic bead isolation of nucleic acids
IL157786A (en) 2003-09-07 2010-11-30 Ahava Dead Sea Lab Ltd Personalized cosmetics
EP1676116B8 (de) 2003-10-21 2012-07-04 Leica Microsystems CMS GmbH Verfahren zur automatischen erzeugung von laser-schnittlinien in der laser-mikrodissektion
CA2542542C (en) 2003-10-21 2015-09-15 Orion Genomics Llc Method of detecting a quantity of methylation at a locus
US7169560B2 (en) 2003-11-12 2007-01-30 Helicos Biosciences Corporation Short cycle methods for sequencing polynucleotides
EP1557449A1 (en) 2004-01-22 2005-07-27 3M Innovative Properties Company Adhesive tape for structural bonding
US20050261210A1 (en) 2004-02-19 2005-11-24 Bhatnagar Rajiv S Nonsense suppressor agents in treatment of cutaneous and gastrointestinal disorders
WO2005091777A2 (en) 2004-02-27 2005-10-06 Nuvelo, Inc. Methods and materials relating to insulin growth factor-like (igfl) polypeptides and polynucleotides
WO2005085477A1 (en) 2004-03-02 2005-09-15 Orion Genomics Llc Differential enzymatic fragmentation by whole genome amplification
JP4526839B2 (ja) 2004-03-05 2010-08-18 株式会社資生堂 角層中の酸化タンパク質を指標とする角層の透明性・保水性を評価する方法
US7183057B2 (en) 2004-03-31 2007-02-27 Dermtech International Tape stripping methods for analysis of skin disease and pathological skin state
US20050287593A1 (en) 2004-05-03 2005-12-29 Schering Corporation Use of cytokine expression to predict skin inflammation; methods of treatment
CN1993480A (zh) 2004-05-03 2007-07-04 先灵公司 Il－17表达预测皮肤炎症的用途；治疗方法
JP4790231B2 (ja) 2004-06-17 2011-10-12 花王株式会社 表皮の解析方法
EP1792181B1 (en) * 2004-06-21 2010-11-17 Progenra Inc. Diagnostic and screening methods and kits associated with proteolytic activity
US20070154889A1 (en) * 2004-06-25 2007-07-05 Veridex, Llc Methods and reagents for the detection of melanoma
ES2323972T3 (es) * 2004-06-25 2009-07-28 Veridex, Llc Metodos y reactivos para la deteccion de melanoma.
US7635563B2 (en) 2004-06-30 2009-12-22 Massachusetts Institute Of Technology High throughput methods relating to microRNA expression analysis
US20080032293A1 (en) 2004-07-15 2008-02-07 The University Of North Carolina At Chapel Hill Housekeeping Genes And Methods For Identifying Same
WO2006039399A2 (en) * 2004-09-29 2006-04-13 University Of Rochester Staufen 1 (stau1) - mediated mrna decay
WO2006043362A1 (ja) 2004-10-19 2006-04-27 Kumamoto University 悪性黒色腫（メラノーマ）の新規な診断キット
US7643818B2 (en) 2004-11-22 2010-01-05 Seven Networks, Inc. E-mail messaging to/from a mobile terminal
EP1817430B1 (en) 2004-11-29 2009-09-16 Klinikum der Universität Regensburg Means and methods for detecting methylated dna
US9063157B2 (en) 2005-03-18 2015-06-23 Shiseido Company, Ltd. Method for evaluating skin condition using squamous cell carcinoma antigen as marker
AU2006235271B2 (en) * 2005-04-07 2011-05-19 Novartis Vaccines And Diagnostics Inc. SEMA4D in cancer diagnosis, detection and treatment
EP1869222A4 (en) 2005-04-15 2010-01-20 Oncomethylome Sciences S A METHYLATION MARKERS FOR THE DIAGNOSIS AND TREATMENT OF CANCER
WO2006128192A2 (en) 2005-05-27 2006-11-30 John Wayne Cancer Institute Use of free circulating dna for diagnosis, prognosis, and treatment of cancer
US20070082347A1 (en) 2005-06-08 2007-04-12 Myriad Genetics, Incorporated Gene variants and use thereof
WO2006135886A2 (en) 2005-06-13 2006-12-21 The Regents Of The University Of Michigan Compositions and methods for treating and diagnosing cancer
JP2007050126A (ja) 2005-08-18 2007-03-01 Dr Ito Procare Cosmetics:Kk 美容方法
WO2007023808A1 (ja) 2005-08-23 2007-03-01 Fancl Corporation 皮膚老化マーカーとその利用技術
US7608395B2 (en) 2005-09-15 2009-10-27 Baylor Research Institute Systemic lupus erythematosus diagnostic assay
US20070243537A1 (en) 2006-04-14 2007-10-18 Tuck Edward F Human sample matching system
CN103149367B (zh) 2005-10-21 2015-04-01 株式会社芳珂 特应性皮炎标记物及其利用技术
CA2630974A1 (en) 2005-11-23 2007-05-31 University Of Utah Research Foundation Methods and compositions involving intrinsic genes
EP1971868A2 (en) 2006-01-05 2008-09-24 Galderma Research & Development, S.N.C. Acne lesions biomarkers and modulators thereof
JP5027528B2 (ja) 2006-03-02 2012-09-19 株式会社ファンケル 皮膚老化の検査方法
US20070281314A1 (en) * 2006-04-20 2007-12-06 Dermtech International Methods for capture and detection of micro-RNA molecules from the skin by non-invasive tape stripping
WO2007127756A2 (en) 2006-04-24 2007-11-08 Genentech, Inc. Methods and compositions for detecting autoimmune disorders
CA2652924A1 (en) 2006-06-19 2007-12-27 Wyeth Methods of modulating il-22 and il-17
WO2008013772A2 (en) 2006-07-27 2008-01-31 Merck & Co., Inc. Automated determination of chlamydia infection-forming units
AU2007292219B2 (en) 2006-09-06 2014-04-24 The Regents Of The University Of California Molecular diagnosis and classification of malignant melanoma
US7615349B2 (en) 2006-09-07 2009-11-10 H. Lee Moffitt Cancer Center And Research Institute, Inc. Melanoma gene signature
WO2008036238A2 (en) 2006-09-19 2008-03-27 Wyeth Use of lxr modulators for the prevention and treatment of skin aging
EP2069377A4 (en) 2006-09-27 2009-11-11 Univ California METHOD AND COMPOSITIONS FOR THE TREATMENT OF SKIN DISEASES AND SKIN FUNCTIONAL DISORDERS
US8148067B2 (en) 2006-11-09 2012-04-03 Xdx, Inc. Methods for diagnosing and monitoring the status of systemic lupus erythematosus
GB0700374D0 (en) 2007-01-09 2007-02-14 Oncomethylome Sciences S A NDRG family methylation markers
US8323899B2 (en) 2007-02-01 2012-12-04 Siemens Healthcare Diagnostics Inc. Silica magnetic particles with a high nucleic acid binding capacity
AU2008247502A1 (en) 2007-05-04 2008-11-13 Dermtech International Diagnosis of melanoma by nucleic acid analysis
US8911937B2 (en) 2007-07-19 2014-12-16 Brainreader Aps Method for detecting methylation status by using methylation-independent primers
WO2009014766A2 (en) 2007-07-26 2009-01-29 The University Of Utah Research Foundation Non-invasive recovery of rna and analysis of gene expression in skin
WO2009018447A2 (en) 2007-07-31 2009-02-05 New York University Diagnostic and treatment methods for characterizing bacterial microbiota in skin conditions
WO2009021141A1 (en) 2007-08-07 2009-02-12 The Johns Hopkins University Comprehensive high throughput arrays for relative methylation
US20090047309A1 (en) 2007-08-13 2009-02-19 Maes Daniel H Cosmetic methods and compositions for repairing human skin
US7965820B2 (en) 2007-08-17 2011-06-21 Brookhaven Science Associates, Llc Fiducial marker for correlating images
KR100999261B1 (ko) 2007-10-09 2010-12-07 (주)아모레퍼시픽 여성호르몬 결핍으로 초래되는 여성 피부의 노화 억제제 스크리닝 방법
EP2053131A1 (en) 2007-10-19 2009-04-29 Ludwig-Maximilians-Universität München Method for determining methylation at deoxycytosine residues
EP2212442A1 (en) 2007-10-26 2010-08-04 Galderma Research & Development Non-invasive method to perform skin inflammatory disease pharmaco-genomic studies and diagnosis method thereof
US20090246768A1 (en) 2008-02-15 2009-10-01 Sawalha Amr H Predicting and Diagnosing Patients With Autoimmune Disease
AU2009221778A1 (en) 2008-03-05 2009-09-11 The Regents Of The University Of California Molecular diagnosis and classification of malignant melanoma
WO2009123373A1 (en) 2008-04-04 2009-10-08 Goodgene Inc. New skin sampling kit which stores nucleic acids in stable status, genetic test methods by using the kit and their practical application
WO2009131733A1 (en) 2008-04-21 2009-10-29 The Trustees Of Columbia University In The City Of New York Gab2 amplification in melanoma
BRPI0913578A2 (pt) 2008-05-14 2017-06-06 Dermtech Int diagnose de melanoma e lentigo solar por análise de ácido nucléico
JP5568807B2 (ja) 2008-06-06 2014-08-13 静岡県 プロテオミクス解析を用いたメラノーママーカーの同定
EP2304048A4 (en) 2008-06-17 2011-07-27 Univ Rochester TUMORSUPPRESSION ABOUT PLEXIN C1
EP2151505A1 (en) 2008-08-05 2010-02-10 Institut Gustave Roussy Method for determining a predisposition to basal cell carcinoma and for screening treatments thereof
EP2977469A1 (en) 2008-08-28 2016-01-27 Dermtech International Determining age ranges of skin samples
JP2012504426A (ja) 2008-10-03 2012-02-23 デイナ ファーバー キャンサー インスティチュート，インコーポレイテッド Ｇｏｌｐｈ３を使用する癌の診断、予後およびモニタリングのための組成物、キットおよび方法
US20100105102A1 (en) 2008-10-22 2010-04-29 Reveal Sciences, Llc Device, method and apparatus for analyzing skin and hair
EP3978928A1 (en) 2008-11-14 2022-04-06 The Brigham and Women's Hospital, Inc. Therapeutic and diagnostic methods relating to cancer stem cells
WO2010056374A2 (en) 2008-11-17 2010-05-20 Veracyte, Inc. Methods and compositions of molecular profiling for disease diagnostics
HU0900117D0 (en) 2009-02-26 2009-04-28 Genetic Immunity Kutatasi Topical or transdermal delivery kit
US20130143747A1 (en) 2011-12-05 2013-06-06 Myriad Genetics, Incorporated Methods of detecting cancer
US20110040571A1 (en) 2009-08-14 2011-02-17 Felicity Warren System and method for providing for teledermatology
WO2011039734A2 (en) 2009-10-02 2011-04-07 Enzo Medico Use of genes involved in anchorage independence for the optimization of diagnosis and treatment of human cancer
EP2488874A4 (en) 2009-10-13 2013-08-14 Univ Johns Hopkins BIOMARKERS FOR THE IDENTIFICATION OF MELANOMOTUM CELLS
GB0921329D0 (en) 2009-12-04 2010-01-20 Univ Surrey Biomarker
CA2798657A1 (en) 2010-02-24 2011-09-01 Alexander Gutin Diagnostic methods involving loss of heterozygosity
US8741561B2 (en) 2010-03-01 2014-06-03 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Gene sets for detection of ultraviolet A exposure and methods of use thereof
AU2011242990B2 (en) 2010-04-19 2015-02-12 Biomarker Strategies, Llc. Compositions and methods for prediction of drug sensitivity, resistance, and disease progression
GB201012590D0 (en) 2010-07-27 2010-09-08 Queen Mary & Westfield College Methods for diagnosing cancer
US9605319B2 (en) 2010-08-30 2017-03-28 Myriad Genetics, Inc. Gene signatures for cancer diagnosis and prognosis
US20140045915A1 (en) 2010-08-31 2014-02-13 The General Hospital Corporation Cancer-related biological materials in microvesicles
WO2012037128A2 (en) 2010-09-14 2012-03-22 The University Of North Carolina At Chapel Hill Methods and kits for detecting melanoma
US20120201750A1 (en) 2010-09-20 2012-08-09 Bungwoo Ryu Serum biomarkers for melanoma metastasis
AU2011305696A1 (en) 2010-09-20 2013-05-02 Advanced Cell Diagnostics, Inc. Biomarkers for differentiating melanoma from benign nevus in the skin
WO2012115885A1 (en) 2011-02-22 2012-08-30 Caris Life Sciences Luxembourg Holdings, S.A.R.L. Circulating biomarkers
WO2012125411A1 (en) 2011-03-11 2012-09-20 Metamark Genetics, Inc. Methods of predicting prognosis in cancer
EP2721179A4 (en) 2011-06-16 2014-10-01 Caris Life Sciences Luxembourg Holdings S A R L BIOMARKER COMPOSITIONS AND METHOD THEREFOR
JP5965481B2 (ja) 2011-07-15 2016-08-03 レオ ファーマ アクティーゼルスカブ 皮膚ｔ細胞リンパ腫（ｃｔｃｌ）の診断用マイクロｒｎａプロファイリング
CN103874770A (zh) 2011-08-08 2014-06-18 卡里斯生命科学卢森堡控股有限责任公司 生物标志物组合物和方法
JP2014525584A (ja) 2011-08-31 2014-09-29 オンコサイト コーポレーション 癌の治療および診断のための方法および組成物
RU2014115845A (ru) 2011-09-21 2015-10-27 Ливинг Пруф, Инк. Композиции и способы лечения состояний нарушенной барьерной функции кожи
WO2013041724A1 (en) 2011-09-23 2013-03-28 Galderma Research & Development Human keratinocytes ptch1 cell line
CN103987861A (zh) 2011-10-14 2014-08-13 加州大学评议会 皮肤鳞状细胞癌和假性上皮瘤样增生的基于多重pcr的测试及其区分方法
AU2012324895B2 (en) 2011-10-19 2017-03-16 Galapagos Nv Antagonists of IL17C for the treatment of inflammatory disorders
WO2013098797A2 (en) 2011-12-31 2013-07-04 Kuriakose Moni Abraham Diagnostic tests for predicting prognosis, recurrence, resistance or sensitivity to therapy and metastatic status in cancer
JP6094481B2 (ja) 2012-05-02 2017-03-15 三菱レイヨン株式会社 皮膚に対する紫外線の影響を評価するためのプローブ又はプローブセット及び核酸マイクロアレイ
WO2013184905A1 (en) 2012-06-06 2013-12-12 Myriad Genetics, Inc. Hereditary cancer genes
EP3626309B1 (en) 2012-08-13 2023-03-08 The Rockefeller University Lxrbeta agonist for the treatment of cancer
DK3435084T3 (da) 2012-08-16 2023-05-30 Mayo Found Medical Education & Res Prostatakræftprognose under anvendelse af biomarkører
US9103749B2 (en) 2012-10-11 2015-08-11 Fast Forward Forensics, LLC Biological sample collection apparatus
US20160051493A1 (en) 2012-11-19 2016-02-25 The Trustees Of Columbia University In The City Of New York Methods of treatment of keratinocyte-derived lesions
TWI493169B (zh) 2013-01-18 2015-07-21 Univ Nat Cheng Kung 評估皮膚生理參數濃度及分布之光學系統及其方法
US10711310B2 (en) 2013-02-18 2020-07-14 Duke University Tert promoter mutations in gliomas and a subset of tumors
WO2014130507A1 (en) 2013-02-22 2014-08-28 Avery Dennison Corporation Multi-layer optically clear adhesives, foams, transfer tapes, and articles comprising such adhesives
WO2014176446A1 (en) 2013-04-26 2014-10-30 Dermtech International Biomarkers for diagnosis and treatment of acne vulgaris
TW201537175A (zh) 2013-06-28 2015-10-01 Chugai Pharmaceutical Co Ltd 預測罹患具皮膚搔癢之疾病的患者對ｉｌ－３１拮抗劑之治療的反應之方法
US20150005184A1 (en) 2013-06-28 2015-01-01 Dermtech International Diagnosis of melanoma by nucleic acid analysis
US20150377751A1 (en) 2013-08-01 2015-12-31 The Procter & Gamble Company Method of collecting and quantifying melanin in skin
FR3011009B1 (fr) 2013-09-25 2016-11-25 Oreal Signature bacterienne de la dermatite atopique et son utilisation dans la prevention et/ou le traitement de cette pathologie
AU2014367369B2 (en) 2013-12-19 2020-03-26 Instytut Biologii Doswiadczalnej Im. M. Nenckiego Polskiej Akademii Nauk A method for detecting an increased risk of developing skin cancer and a use of a genotype variant of the GRHL3 gene
WO2019161126A1 (en) 2018-02-14 2019-08-22 Dermtech, Inc. Novel gene classifiers and uses thereof in non-melanoma skin cancers
US20220162682A1 (en) 2020-11-24 2022-05-26 Dermtech, Inc. Assessment of mutation burden in skin
WO2022187196A1 (en) 2021-03-02 2022-09-09 Dermtech, Inc. Predicting therapeutic response
WO2022221326A1 (en) 2021-04-13 2022-10-20 Dermtech, Inc. Gene classifiers and uses thereof
WO2015184061A2 (en) 2014-05-28 2015-12-03 Dana-Farber Cancer Institute, Inc. Activating jak kinase biomarkers predictive of anti-immune checkpoint inhibitor response
US20160000936A1 (en) 2014-06-10 2016-01-07 Abbvie Inc. Biomarkers for inflammatory disease and methods of using same
US20160024595A1 (en) 2014-07-22 2016-01-28 Dermtech International Characterization of melanoma using a molecular signature
US10456870B2 (en) 2014-08-27 2019-10-29 Heraeus Deutschland GmbH & Co. KG Method for producing a soldered connection
US10709428B2 (en) 2015-05-01 2020-07-14 Dermtech, Inc. Non-invasive skin collection system
WO2017083576A1 (en) 2015-11-10 2017-05-18 Pathway Genomics Corporation Methods and systems for improving skin condition
US10852307B2 (en) 2015-12-22 2020-12-01 National Jewish Health Methods of detecting and preventing atopic allergic diseases
MX2018010362A (es) 2016-02-29 2019-03-28 Found Medicine Inc Metodos y sistemas para evaluar carga mutacional de tumores.
WO2017165199A1 (en) 2016-03-25 2017-09-28 The Trustees Of Columbia University In The City Of New York Next-generation biomarkers to detect sun damage and predict skin cancer risk
US20170329929A1 (en) 2016-05-11 2017-11-16 Sensus Healthcare Llc Virtual pathology for dermatology
CN106119242A (zh) 2016-06-24 2016-11-16 毕建红 一种基于自动化工作站的疑难微量法医物证dna提取试剂盒及其方法
CN110022875A (zh) 2016-07-11 2019-07-16 莱福斯希医药公司 治疗性抑制化合物
WO2018065384A1 (en) 2016-10-03 2018-04-12 Galderma Research & Development Expression profiles of abc and slc transporters in human and minipig skin, liver and kidney
CN110140040A (zh) 2016-11-09 2019-08-16 豪夫迈·罗氏有限公司 自动化的组织切割仪器及其使用方法
EP3541826B1 (en) 2016-11-15 2023-09-27 Quest Diagnostics Investments LLC Methods for detecting dna mutations using mitra tip extraction
FR3060755B1 (fr) 2016-12-16 2024-07-12 Oreal Methode de diagnostic d'une peau presentant des signes de secheresse
WO2018161062A1 (en) 2017-03-03 2018-09-07 Children's Hospital Medical Center Non-invasive methods for skin sample collection and analysis
AU2018251770B2 (en) 2017-04-10 2024-03-14 Dermtech, Llc Non-invasive skin-based detection methods
EP3645028B1 (en) 2017-06-27 2025-07-09 Institute For Cancer Research d/b/a The Research Institute of Fox Chase Cancer Center Mhc-1 genotype restricts the oncogenic mutational landscape
CA3099275A1 (en) 2018-05-09 2019-11-14 Dermtech, Inc. Novel gene classifiers and uses thereof in autoimmune diseases
US20190369119A1 (en) 2018-06-04 2019-12-05 Avon Products, Inc. Protein Biomarkers for Identifying and Treating Aging Skin and Skin Conditions
GB201810897D0 (en) 2018-07-03 2018-08-15 Chronomics Ltd Phenotype prediction
GB2576374A (en) 2018-08-17 2020-02-19 Ecole Polytechnique Fed Lausanne Epfl Skin cell analysis
CN109785903A (zh) 2018-12-29 2019-05-21 哈尔滨工业大学（深圳） 一种基因表达数据分类器
WO2020198229A1 (en) 2019-03-26 2020-10-01 Dermtech, Inc. Novel gene classifiers and uses thereof in skin cancers
CA3136108A1 (en) 2019-04-05 2020-10-08 Dermtech, Inc. Novel gene classifiers for use in monitoring uv damage
JP2023522952A (ja) 2020-04-22 2023-06-01 ダームテック，インク． 遠隔皮膚科診断のシステムと方法
EP4147043A4 (en) 2020-05-08 2024-04-24 Dermtech, Inc. Automated sample scanning and segregation system and methods
EP4346624A4 (en) 2021-06-04 2025-03-26 Dermtech, Inc. Sample collection system

Also Published As

Publication number Publication date
US20210198749A1 (en) 2021-07-01
AU2009246180A1 (en) 2009-11-19
US20140154684A1 (en) 2014-06-05
AU2009246180B2 (en) 2015-11-05
US20210246514A1 (en) 2021-08-12
US20210222258A1 (en) 2021-07-22
EP2626437A2 (en) 2013-08-14
US20190367994A1 (en) 2019-12-05
CA2724322A1 (en) 2009-11-19
US11753687B2 (en) 2023-09-12
EP2294216A4 (en) 2011-11-23
JP2011520451A (ja) 2011-07-21
US10407729B2 (en) 2019-09-10
US20110160080A1 (en) 2011-06-30
US9057109B2 (en) 2015-06-16
EP2294216A2 (en) 2011-03-16
US11332795B2 (en) 2022-05-17
US20140256584A1 (en) 2014-09-11
WO2009140550A3 (en) 2010-02-25
CN102089444A (zh) 2011-06-08
US20150361509A1 (en) 2015-12-17
EP2626437A3 (en) 2013-12-11
WO2009140550A2 (en) 2009-11-19
WO2009140550A9 (en) 2010-01-07
BRPI0913578A2 (pt) 2017-06-06

Similar Documents

Publication Publication Date Title
US11753687B2 (en) Diagnosis of melanoma and solar lentigo by nucleic acid analysis
US20080274908A1 (en) Diagnosis of melanoma by nucleic acid analysis
Prueitt et al. Expression of microRNAs and protein‐coding genes associated with perineural invasion in prostate cancer
AU2009285645B2 (en) Determining age ranges of skin samples
US20150005184A1 (en) Diagnosis of melanoma by nucleic acid analysis
US20090192045A1 (en) Molecular staging of stage ii and iii colon cancer and prognosis
WO2014176446A1 (en) Biomarkers for diagnosis and treatment of acne vulgaris
WO2012093821A2 (ko) 초기유방암의 예후 예측용 유전자 및 이를 이용한 초기유방암의 예후예측 방법
US20140100125A1 (en) Methods, Kits and Compositions for Determining Severity and Survival of Heart Failure in a Subject
Hwang et al. Genomic copy number alterations as predictive markers of systemic recurrence in breast cancer
US20150329911A1 (en) Nucleic acid biomarkers for prostate cancer
Class et al. Patent application title: DIAGNOSIS OF MELANOMA AND SOLAR LENTIGO BY NUCLEIC ACID ANALYSIS Inventors: Sherman H. Chang (San Diego, CA, US) Sherman H. Chang (San Diego, CA, US)
HK1155781A (en) Method and apparatus for determining a probability of colorectal cancer in a subject

Legal Events

Date Code Title Description
EEER Examination request

Effective date: 20140513

R11 Change to the name of applicant or owner or transfer of ownership requested

Free format text: ST27 STATUS EVENT CODE: A-4-4-R10-R11-R127 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: TRANSFER RECORDAL REQUEST OR RESPONSE

Effective date: 20250306

W00 Other event occurred

Free format text: ST27 STATUS EVENT CODE: A-4-4-W10-W00-W111 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: CORRESPONDENT DETERMINED COMPLIANT

Effective date: 20250423

MPN Maintenance fee for patent paid

Free format text: FEE DESCRIPTION TEXT: MF (PATENT, 16TH ANNIV.) - STANDARD

Year of fee payment: 16

U00 Fee paid

Free format text: ST27 STATUS EVENT CODE: A-4-4-U10-U00-U101 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE REQUEST RECEIVED

Effective date: 20250509

U11 Full renewal or maintenance fee paid

Free format text: ST27 STATUS EVENT CODE: A-4-4-U10-U11-U102 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE FEE PAYMENT PAID IN FULL

Effective date: 20250509

R14 Transfer of ownership recorded

Free format text: ST27 STATUS EVENT CODE: A-4-4-R10-R14-R129 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: TRANSFER REQUIREMENTS DETERMINED COMPLIANT

Effective date: 20251117