BRPI0512587A - processo e reagentes para detecção de melanoma - Google Patents

processo e reagentes para detecção de melanoma

Info

Publication number
BRPI0512587A
BRPI0512587A BRPI0512587-1A BRPI0512587A BRPI0512587A BR PI0512587 A BRPI0512587 A BR PI0512587A BR PI0512587 A BRPI0512587 A BR PI0512587A BR PI0512587 A BRPI0512587 A BR PI0512587A
Authority
BR
Brazil
Prior art keywords
reagents
detection process
melanoma
melanoma detection
assay
Prior art date
Application number
BRPI0512587-1A
Other languages
English (en)
Inventor
Yixin Wang
Dimitri Talantov
Abhijit Mazumder
Original Assignee
Veridex Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Veridex Llc filed Critical Veridex Llc
Publication of BRPI0512587A publication Critical patent/BRPI0512587A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
    • C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/112—Disease subtyping, staging or classification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/16—Primer sets for multiplex assays
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A90/00—Technologies having an indirect contribution to adaptation to climate change
    • Y02A90/10—Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Hospice & Palliative Care (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)

Abstract

PROCESSOS E REAGENTES PARA DETECçãO DE MELANOMA. A presente invenção refere-se a um ensaio para identificar um melanócito maligno é conduzido determinando se a expressão diferencial de genes particulares indicativa de melanoma excede a um valor de corte. O ensaio pode ser executado intra-operativamente em tecido de linfonodo.
BRPI0512587-1A 2004-06-25 2005-06-24 processo e reagentes para detecção de melanoma BRPI0512587A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US58290604P 2004-06-25 2004-06-25
PCT/US2005/022846 WO2006002433A2 (en) 2004-06-24 2005-06-24 Methods and reagents for the detection of melanoma

Publications (1)

Publication Number Publication Date
BRPI0512587A true BRPI0512587A (pt) 2007-09-18

Family

ID=35782385

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0512587-1A BRPI0512587A (pt) 2004-06-25 2005-06-24 processo e reagentes para detecção de melanoma

Country Status (16)

Country Link
EP (1) EP1812590B1 (pt)
JP (1) JP2008504034A (pt)
KR (1) KR20070048701A (pt)
CN (1) CN101258249A (pt)
AT (1) ATE428808T1 (pt)
AU (1) AU2005258331B2 (pt)
BR (1) BRPI0512587A (pt)
CA (1) CA2572338A1 (pt)
DE (1) DE602005013998D1 (pt)
DK (1) DK1812590T3 (pt)
ES (1) ES2323972T3 (pt)
IL (1) IL180208A0 (pt)
MX (1) MX2007000291A (pt)
NZ (1) NZ552324A (pt)
PT (1) PT1812590E (pt)
WO (1) WO2006002433A2 (pt)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104673905B (zh) 2005-06-20 2016-09-07 领先细胞医疗诊断有限公司 检测单个细胞中的核酸和鉴定异质大细胞群中罕见细胞的方法
WO2007035690A2 (en) * 2005-09-19 2007-03-29 Veridex, Llc Methods for diagnosing pancreatic cancer
FR2890859B1 (fr) 2005-09-21 2012-12-21 Oreal Oligonucleotide d'arn double brin inhibant l'expression de la tyrosinase
US20100029504A1 (en) 2007-01-16 2010-02-04 Phigenix, Inc. Detecting pax2 for the diagnosis of breast cancer
JP2007289063A (ja) 2006-04-25 2007-11-08 Shiseido Co Ltd しみ部位亢進遺伝子群を指標とした皮膚しみ形成予知方法、皮膚しみ形成抑制剤のスクリーニング方法
US7851144B2 (en) 2006-08-18 2010-12-14 The University Of Washington Compositions and methods for detecting cancer
BRPI0807227A2 (pt) * 2007-02-01 2019-01-22 Veridex Llc métodos e materiais para identificação da origem de um carcinoma de origem primária desconhecida
WO2008141275A1 (en) * 2007-05-11 2008-11-20 The Johns Hopkins University Biomarkers for melanoma
CN102089444A (zh) 2008-05-14 2011-06-08 德玛泰克国际公司 利用核酸分析方法来诊断黑素瘤和太阳能雀斑
IL206810A (en) * 2009-07-08 2015-07-30 Janssen Diagnostics Llc Methods for identifying melanoma and kits for using these methods
JP2013013327A (ja) * 2009-10-29 2013-01-24 Actgen Inc Ｍａｎｓｃ１蛋白質に結合し、抗癌活性を有する抗体
EP2619321B1 (en) * 2010-09-20 2018-08-01 Advanced Cell Diagnostics, Inc. Biomarkers for differentiating melanoma from benign nevus in the skin
CN107365847A (zh) 2010-10-21 2017-11-21 领先细胞医疗诊断有限公司 用于原位检测核酸的超灵敏方法
EP2864500B1 (en) * 2012-06-22 2018-08-22 HTG Molecular Diagnostics, Inc. Molecular malignancy in melanocytic lesions
EP3913068B1 (en) 2015-10-12 2023-08-02 Advanced Cell Diagnostics, Inc. In situ detection of nucleotide variants in high noise samples, and compositions and methods related thereto
CN105331686B (zh) * 2015-10-21 2018-09-21 中国科学院生物物理研究所 Myosin9b蛋白特异性抗体的制备及Myosin9b基因家族变化在肿瘤诊断及预后中的应用
EP3526259A4 (en) * 2016-10-13 2020-06-17 Dana-Farber Cancer Institute, Inc. COMPOSITIONS AND METHODS FOR PREDICTING THE REACTION AND RESISTANCE TO A CTLA4 BLOCKAGE IN MELANOMAS USING A GENE EXPRESSION SIGNATURE
CN106884018B (zh) * 2017-01-19 2021-03-23 江苏大学 一种检测致癌蛋白表皮生长因子受体的试剂及试剂盒
US11976332B2 (en) 2018-02-14 2024-05-07 Dermtech, Inc. Gene classifiers and uses thereof in non-melanoma skin cancers
CN109371113A (zh) * 2018-10-29 2019-02-22 湖南健基生物技术有限公司 一种检测人类apoe和slco1b1基因多态性的组合物、试剂盒、样品处理方法和应用
AU2020247911A1 (en) 2019-03-26 2021-11-11 Dermtech, Inc. Novel gene classifiers and uses thereof in skin cancers
CN112773730B (zh) * 2021-01-28 2023-01-03 南昌大学 微小rna在美白护肤产品中的应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5310652A (en) * 1986-08-22 1994-05-10 Hoffman-La Roche Inc. Reverse transcription with thermostable DNA polymerase-high temperature reverse transcription
DE19949594A1 (de) * 1999-10-14 2001-04-26 Deutsches Krebsforsch Rekombinante attenuierte Listerien zur Immuntherapie
CA2411601A1 (en) * 2000-06-05 2001-12-13 Avalon Pharmaceuticals Cancer gene determination and therapeutic screening using signature gene sets
WO2002027028A1 (en) * 2000-09-28 2002-04-04 Atairgin Technologies, Inc. A method of determining tumor characteristics by determining abnormal copy number or expression level of lipid-associated genes
AU2003268275C1 (en) * 2002-08-29 2010-04-01 Cytocure Llc Methods for up-regulating antigen expression in tumors
US20060188889A1 (en) * 2003-11-04 2006-08-24 Christopher Burgess Use of differentially expressed nucleic acid sequences as biomarkers for cancer

Also Published As

Publication number Publication date
DK1812590T3 (da) 2009-07-13
ES2323972T3 (es) 2009-07-28
JP2008504034A (ja) 2008-02-14
IL180208A0 (en) 2007-07-04
PT1812590E (pt) 2009-07-06
MX2007000291A (es) 2007-08-07
WO2006002433A2 (en) 2006-01-05
EP1812590B1 (en) 2009-04-15
NZ552324A (en) 2009-11-27
CA2572338A1 (en) 2006-01-05
AU2005258331B2 (en) 2009-12-10
DE602005013998D1 (de) 2009-05-28
CN101258249A (zh) 2008-09-03
ATE428808T1 (de) 2009-05-15
AU2005258331A1 (en) 2006-01-05
WO2006002433A3 (en) 2006-08-24
KR20070048701A (ko) 2007-05-09
EP1812590A2 (en) 2007-08-01

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B11E Dismissal acc. art. 34 of ipl - requirements for examination incomplete
B11T Dismissal of application maintained [chapter 11.20 patent gazette]