CA2698017C - Bone cement mixing and delivery system and methods of use thereof - Google Patents
Bone cement mixing and delivery system and methods of use thereof Download PDFInfo
- Publication number
- CA2698017C CA2698017C CA2698017A CA2698017A CA2698017C CA 2698017 C CA2698017 C CA 2698017C CA 2698017 A CA2698017 A CA 2698017A CA 2698017 A CA2698017 A CA 2698017A CA 2698017 C CA2698017 C CA 2698017C
- Authority
- CA
- Canada
- Prior art keywords
- tube
- powder
- tubes
- bone cement
- gas
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 238000002156 mixing Methods 0.000 title claims abstract description 44
- 238000000034 method Methods 0.000 title claims abstract description 25
- 239000002639 bone cement Substances 0.000 title claims abstract description 23
- 239000000843 powder Substances 0.000 claims abstract description 66
- 239000012530 fluid Substances 0.000 claims abstract description 20
- 238000004891 communication Methods 0.000 claims abstract description 6
- 239000001506 calcium phosphate Substances 0.000 claims description 42
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical group [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 claims description 41
- 229910000389 calcium phosphate Inorganic materials 0.000 claims description 39
- 235000011010 calcium phosphates Nutrition 0.000 claims description 39
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims description 12
- 239000011780 sodium chloride Substances 0.000 claims description 12
- 230000004888 barrier function Effects 0.000 claims description 9
- 230000000881 depressing effect Effects 0.000 claims description 9
- 239000002274 desiccant Substances 0.000 claims description 9
- 238000013022 venting Methods 0.000 claims description 9
- 238000004806 packaging method and process Methods 0.000 claims description 4
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 4
- 239000013060 biological fluid Substances 0.000 claims description 3
- 239000008363 phosphate buffer Substances 0.000 claims description 3
- 239000007788 liquid Substances 0.000 abstract description 21
- 238000013461 design Methods 0.000 abstract description 3
- 239000000203 mixture Substances 0.000 description 28
- 239000000463 material Substances 0.000 description 27
- 239000004568 cement Substances 0.000 description 15
- 210000002381 plasma Anatomy 0.000 description 8
- 210000004369 blood Anatomy 0.000 description 7
- 239000008280 blood Substances 0.000 description 7
- 239000011575 calcium Substances 0.000 description 7
- 239000007789 gas Substances 0.000 description 6
- 238000012546 transfer Methods 0.000 description 6
- 210000000988 bone and bone Anatomy 0.000 description 5
- 239000000306 component Substances 0.000 description 5
- FUFJGUQYACFECW-UHFFFAOYSA-L calcium hydrogenphosphate Chemical compound [Ca+2].OP([O-])([O-])=O FUFJGUQYACFECW-UHFFFAOYSA-L 0.000 description 4
- RBLGLDWTCZMLRW-UHFFFAOYSA-K dicalcium phosphate dihydrate Substances O.O.[Ca+2].[Ca+2].[O-]P([O-])([O-])=O RBLGLDWTCZMLRW-UHFFFAOYSA-K 0.000 description 4
- 229910052588 hydroxylapatite Inorganic materials 0.000 description 4
- XYJRXVWERLGGKC-UHFFFAOYSA-D pentacalcium;hydroxide;triphosphate Chemical compound [OH-].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O XYJRXVWERLGGKC-UHFFFAOYSA-D 0.000 description 4
- -1 polypropylene Polymers 0.000 description 4
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 description 3
- 239000013543 active substance Substances 0.000 description 3
- 229910052586 apatite Inorganic materials 0.000 description 3
- 239000003795 chemical substances by application Substances 0.000 description 3
- 238000011109 contamination Methods 0.000 description 3
- VSIIXMUUUJUKCM-UHFFFAOYSA-D pentacalcium;fluoride;triphosphate Chemical compound [F-].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O VSIIXMUUUJUKCM-UHFFFAOYSA-D 0.000 description 3
- 238000002360 preparation method Methods 0.000 description 3
- XKRFYHLGVUSROY-UHFFFAOYSA-N Argon Chemical compound [Ar] XKRFYHLGVUSROY-UHFFFAOYSA-N 0.000 description 2
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 2
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 2
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 description 2
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 2
- KKEYFWRCBNTPAC-UHFFFAOYSA-N Terephthalic acid Chemical compound OC(=O)C1=CC=C(C(O)=O)C=C1 KKEYFWRCBNTPAC-UHFFFAOYSA-N 0.000 description 2
- 239000012503 blood component Substances 0.000 description 2
- 229910052791 calcium Inorganic materials 0.000 description 2
- JUNWLZAGQLJVLR-UHFFFAOYSA-J calcium diphosphate Chemical compound [Ca+2].[Ca+2].[O-]P([O-])(=O)OP([O-])([O-])=O JUNWLZAGQLJVLR-UHFFFAOYSA-J 0.000 description 2
- ROPDWRCJTIRLTR-UHFFFAOYSA-L calcium metaphosphate Chemical compound [Ca+2].[O-]P(=O)=O.[O-]P(=O)=O ROPDWRCJTIRLTR-UHFFFAOYSA-L 0.000 description 2
- 229940043256 calcium pyrophosphate Drugs 0.000 description 2
- 230000015556 catabolic process Effects 0.000 description 2
- 210000004027 cell Anatomy 0.000 description 2
- 238000005056 compaction Methods 0.000 description 2
- 230000006835 compression Effects 0.000 description 2
- 238000007906 compression Methods 0.000 description 2
- 230000007547 defect Effects 0.000 description 2
- 230000002950 deficient Effects 0.000 description 2
- 238000006731 degradation reaction Methods 0.000 description 2
- 235000019821 dicalcium diphosphate Nutrition 0.000 description 2
- 239000004023 fresh frozen plasma Substances 0.000 description 2
- 239000011521 glass Substances 0.000 description 2
- KBQIPTXDQGPPIO-UHFFFAOYSA-K heptacalcium;phosphate Chemical compound [Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O KBQIPTXDQGPPIO-UHFFFAOYSA-K 0.000 description 2
- 230000036571 hydration Effects 0.000 description 2
- 238000006703 hydration reaction Methods 0.000 description 2
- 238000001727 in vivo Methods 0.000 description 2
- 238000002347 injection Methods 0.000 description 2
- 239000007924 injection Substances 0.000 description 2
- 229910000392 octacalcium phosphate Inorganic materials 0.000 description 2
- 239000004033 plastic Substances 0.000 description 2
- 229920003023 plastic Polymers 0.000 description 2
- 210000004623 platelet-rich plasma Anatomy 0.000 description 2
- 229920000642 polymer Polymers 0.000 description 2
- 238000003825 pressing Methods 0.000 description 2
- 230000008439 repair process Effects 0.000 description 2
- 239000000243 solution Substances 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- YIGWVOWKHUSYER-UHFFFAOYSA-F tetracalcium;hydrogen phosphate;diphosphate Chemical compound [Ca+2].[Ca+2].[Ca+2].[Ca+2].OP([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O YIGWVOWKHUSYER-UHFFFAOYSA-F 0.000 description 2
- GBNXLQPMFAUCOI-UHFFFAOYSA-H tetracalcium;oxygen(2-);diphosphate Chemical compound [O-2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O GBNXLQPMFAUCOI-UHFFFAOYSA-H 0.000 description 2
- 239000003634 thrombocyte concentrate Substances 0.000 description 2
- 229910000391 tricalcium phosphate Inorganic materials 0.000 description 2
- 235000019731 tricalcium phosphate Nutrition 0.000 description 2
- 229940078499 tricalcium phosphate Drugs 0.000 description 2
- 238000009736 wetting Methods 0.000 description 2
- 238000005033 Fourier transform infrared spectroscopy Methods 0.000 description 1
- 229910019142 PO4 Inorganic materials 0.000 description 1
- 239000004698 Polyethylene Substances 0.000 description 1
- 239000004743 Polypropylene Substances 0.000 description 1
- 239000004793 Polystyrene Substances 0.000 description 1
- 230000006978 adaptation Effects 0.000 description 1
- 239000003570 air Substances 0.000 description 1
- 239000003146 anticoagulant agent Substances 0.000 description 1
- 229940127219 anticoagulant drug Drugs 0.000 description 1
- 229910052786 argon Inorganic materials 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 230000005540 biological transmission Effects 0.000 description 1
- 239000010836 blood and blood product Substances 0.000 description 1
- 229940125691 blood product Drugs 0.000 description 1
- 210000001185 bone marrow Anatomy 0.000 description 1
- YYRMJZQKEFZXMX-UHFFFAOYSA-L calcium bis(dihydrogenphosphate) Chemical compound [Ca+2].OP(O)([O-])=O.OP(O)([O-])=O YYRMJZQKEFZXMX-UHFFFAOYSA-L 0.000 description 1
- 239000001569 carbon dioxide Substances 0.000 description 1
- 229910002092 carbon dioxide Inorganic materials 0.000 description 1
- 239000000919 ceramic Substances 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 239000004927 clay Substances 0.000 description 1
- VEIOBOXBGYWJIT-UHFFFAOYSA-N cyclohexane;methanol Chemical compound OC.OC.C1CCCCC1 VEIOBOXBGYWJIT-UHFFFAOYSA-N 0.000 description 1
- 238000000354 decomposition reaction Methods 0.000 description 1
- 239000011888 foil Substances 0.000 description 1
- 239000001307 helium Substances 0.000 description 1
- 229910052734 helium Inorganic materials 0.000 description 1
- SWQJXJOGLNCZEY-UHFFFAOYSA-N helium atom Chemical compound [He] SWQJXJOGLNCZEY-UHFFFAOYSA-N 0.000 description 1
- 230000000887 hydrating effect Effects 0.000 description 1
- 239000007943 implant Substances 0.000 description 1
- 238000005304 joining Methods 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000007769 metal material Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 239000002808 molecular sieve Substances 0.000 description 1
- 229910000150 monocalcium phosphate Inorganic materials 0.000 description 1
- 235000019691 monocalcium phosphate Nutrition 0.000 description 1
- 229910052757 nitrogen Inorganic materials 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- 230000000399 orthopedic effect Effects 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 239000006072 paste Substances 0.000 description 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 1
- 239000010452 phosphate Substances 0.000 description 1
- 239000004417 polycarbonate Substances 0.000 description 1
- 229920000515 polycarbonate Polymers 0.000 description 1
- 229920000573 polyethylene Polymers 0.000 description 1
- 229920005644 polyethylene terephthalate glycol copolymer Polymers 0.000 description 1
- 229920001155 polypropylene Polymers 0.000 description 1
- 229920002223 polystyrene Polymers 0.000 description 1
- 239000011148 porous material Substances 0.000 description 1
- 239000002243 precursor Substances 0.000 description 1
- 239000003755 preservative agent Substances 0.000 description 1
- 230000002335 preservative effect Effects 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 210000002966 serum Anatomy 0.000 description 1
- 239000000741 silica gel Substances 0.000 description 1
- 229910002027 silica gel Inorganic materials 0.000 description 1
- 239000002002 slurry Substances 0.000 description 1
- URGAHOPLAPQHLN-UHFFFAOYSA-N sodium aluminosilicate Chemical compound [Na+].[Al+3].[O-][Si]([O-])=O.[O-][Si]([O-])=O URGAHOPLAPQHLN-UHFFFAOYSA-N 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 230000000153 supplemental effect Effects 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 238000012800 visualization Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
- A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws or setting implements
- A61B17/88—Osteosynthesis instruments; Methods or means for implanting or extracting internal or external fixation devices
- A61B17/8802—Equipment for handling bone cement or other fluid fillers
- A61B17/8833—Osteosynthesis tools specially adapted for handling bone cement or fluid fillers; Means for supplying bone cement or fluid fillers to introducing tools, e.g. cartridge handling means
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
- B01F25/40—Static mixers
- B01F25/45—Mixers in which the materials to be mixed are pressed together through orifices or interstitial spaces, e.g. between beads
- B01F25/451—Mixers in which the materials to be mixed are pressed together through orifices or interstitial spaces, e.g. between beads characterised by means for moving the materials to be mixed or the mixture
- B01F25/4512—Mixers in which the materials to be mixed are pressed together through orifices or interstitial spaces, e.g. between beads characterised by means for moving the materials to be mixed or the mixture with reciprocating pistons
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
- B01F25/40—Static mixers
- B01F25/45—Mixers in which the materials to be mixed are pressed together through orifices or interstitial spaces, e.g. between beads
- B01F25/452—Mixers in which the materials to be mixed are pressed together through orifices or interstitial spaces, e.g. between beads characterised by elements provided with orifices or interstitial spaces
- B01F25/4521—Mixers in which the materials to be mixed are pressed together through orifices or interstitial spaces, e.g. between beads characterised by elements provided with orifices or interstitial spaces the components being pressed through orifices in elements, e.g. flat plates or cylinders, which obstruct the whole diameter of the tube
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F31/00—Mixers with shaking, oscillating, or vibrating mechanisms
- B01F31/65—Mixers with shaking, oscillating, or vibrating mechanisms the materials to be mixed being directly submitted to a pulsating movement, e.g. by means of an oscillating piston or air column
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
- B01F35/71—Feed mechanisms
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
- B01F35/71—Feed mechanisms
- B01F35/712—Feed mechanisms for feeding fluids
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
- B01F35/71—Feed mechanisms
- B01F35/716—Feed mechanisms characterised by the relative arrangement of the containers for feeding or mixing the components
- B01F35/7161—Feed mechanisms characterised by the relative arrangement of the containers for feeding or mixing the components the containers being connected coaxially before contacting the contents
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
- B01F35/71—Feed mechanisms
- B01F35/716—Feed mechanisms characterised by the relative arrangement of the containers for feeding or mixing the components
- B01F35/7163—Feed mechanisms characterised by the relative arrangement of the containers for feeding or mixing the components the containers being connected in a mouth-to-mouth, end-to-end disposition, i.e. the openings are juxtaposed before contacting the contents
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
- B01F35/71—Feed mechanisms
- B01F35/717—Feed mechanisms characterised by the means for feeding the components to the mixer
- B01F35/7174—Feed mechanisms characterised by the means for feeding the components to the mixer using pistons, plungers or syringes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
- B01F35/75—Discharge mechanisms
- B01F35/754—Discharge mechanisms characterised by the means for discharging the components from the mixer
- B01F35/75425—Discharge mechanisms characterised by the means for discharging the components from the mixer using pistons or plungers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
- A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws or setting implements
- A61B17/88—Osteosynthesis instruments; Methods or means for implanting or extracting internal or external fixation devices
- A61B17/8802—Equipment for handling bone cement or other fluid fillers
- A61B17/8805—Equipment for handling bone cement or other fluid fillers for introducing fluid filler into bone or extracting it
- A61B17/8827—Equipment for handling bone cement or other fluid fillers for introducing fluid filler into bone or extracting it with filtering, degassing, venting or pressure relief means
Landscapes
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Surgery (AREA)
- Dispersion Chemistry (AREA)
- Heart & Thoracic Surgery (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Materials For Medical Uses (AREA)
- Surgical Instruments (AREA)
- Mixers With Rotating Receptacles And Mixers With Vibration Mechanisms (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CA2928681A CA2928681C (en) | 2007-08-29 | 2008-08-28 | Bone cement mixing and delivery system and methods of use thereof |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US96657907P | 2007-08-29 | 2007-08-29 | |
| US60/966,579 | 2007-08-29 | ||
| PCT/US2008/010214 WO2009032173A1 (en) | 2007-08-29 | 2008-08-28 | Bone cement mixing and delivery system and methods of use thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2928681A Division CA2928681C (en) | 2007-08-29 | 2008-08-28 | Bone cement mixing and delivery system and methods of use thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2698017A1 CA2698017A1 (en) | 2009-03-12 |
| CA2698017C true CA2698017C (en) | 2016-12-13 |
Family
ID=40429189
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2698017A Active CA2698017C (en) | 2007-08-29 | 2008-08-28 | Bone cement mixing and delivery system and methods of use thereof |
| CA2928681A Active CA2928681C (en) | 2007-08-29 | 2008-08-28 | Bone cement mixing and delivery system and methods of use thereof |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2928681A Active CA2928681C (en) | 2007-08-29 | 2008-08-28 | Bone cement mixing and delivery system and methods of use thereof |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US9427715B2 (enExample) |
| EP (1) | EP2200523B1 (enExample) |
| JP (1) | JP2010537718A (enExample) |
| KR (1) | KR101634664B1 (enExample) |
| CN (1) | CN101835434A (enExample) |
| AU (1) | AU2008296990B2 (enExample) |
| CA (2) | CA2698017C (enExample) |
| WO (1) | WO2009032173A1 (enExample) |
Families Citing this family (59)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1928520B1 (en) * | 2005-09-07 | 2011-11-09 | Thomas Steffen | Device for injecting high viscosity material |
| KR101634664B1 (ko) | 2007-08-29 | 2016-06-29 | 에텍스 코포레이션 | 골 시멘트 혼합 및 전달 시스템 및 그의 사용 방법 |
| KR101692911B1 (ko) | 2008-04-15 | 2017-01-17 | 라이프 사이언스 엔터프라이즈 | 칼슘 포스페이트 혼합 골 시멘트를 이용한 척추의 최소 침습적 치료방법 |
| ES2554169T3 (es) * | 2008-07-15 | 2015-12-16 | Thomas Steffen | Dispositivo de inyección de cemento óseo |
| CN102232860A (zh) * | 2010-04-26 | 2011-11-09 | 邵卫星 | 一种骨水泥注入器及向骨水泥注入器中装入骨水泥的方法 |
| GB201014514D0 (en) * | 2010-09-01 | 2010-10-13 | Biocomposites Ltd | Mixing and dispensing apparatus for bone void filler |
| USD663833S1 (en) | 2010-11-11 | 2012-07-17 | Pioneer Surgical Technology, Inc. | Mixing syringe |
| US8864708B1 (en) | 2010-12-03 | 2014-10-21 | Medical Device Engineering, LLC. | Tamper indicating closure assembly |
| WO2012082773A1 (en) * | 2010-12-13 | 2012-06-21 | Biomimetic Therapeutics, Inc. | Compositions and methods for spine fusion procedures |
| US9101429B2 (en) * | 2011-04-27 | 2015-08-11 | Jiin-Huey Chern Lin | Method and apparatus for delivering cement paste into a bone cavity |
| DE102011101486A1 (de) | 2011-05-13 | 2012-11-15 | Heraeus Medical Gmbh | Vorrichtung und Verfahren zum Entgasen und Austragen von Knochenzement |
| US9604184B2 (en) | 2013-03-06 | 2017-03-28 | Orthovita, Inc. | Mixing system and valve assembly |
| US10912898B1 (en) | 2014-02-03 | 2021-02-09 | Medical Device Engineering Llc | Tamper evident cap for medical fitting |
| US10207099B1 (en) | 2014-02-21 | 2019-02-19 | Patrick Vitello | Closure assembly for medical fitting |
| US10166347B1 (en) | 2014-07-18 | 2019-01-01 | Patrick Vitello | Closure assembly for a medical device |
| US10576020B2 (en) * | 2015-06-18 | 2020-03-03 | Neomed, Inc. | Syringe-to-syringe coupler |
| US10773067B2 (en) | 2014-09-08 | 2020-09-15 | Neomed, Inc. | Enteral connectors having coupling features |
| US10300263B1 (en) | 2015-02-27 | 2019-05-28 | Timothy Brandon Hunt | Closure assembly for a medical connector |
| US10166343B1 (en) | 2015-03-13 | 2019-01-01 | Timothy Brandon Hunt | Noise evident tamper cap |
| US10315024B1 (en) | 2015-03-19 | 2019-06-11 | Patick Vitello | Torque limiting closure assembly |
| CN104873264B (zh) * | 2015-06-09 | 2016-12-07 | 刘训伟 | 用于树脂类骨水泥和磷酸钙骨水泥联合灌注的设备 |
| USD825746S1 (en) | 2015-06-18 | 2018-08-14 | Neomed, Inc. | Syringe-to-syringe coupler |
| WO2017011754A1 (en) | 2015-07-15 | 2017-01-19 | Neomed, Inc. | Enteral adaptor couplings |
| EP3419582B1 (en) | 2016-02-24 | 2022-07-13 | Avent, Inc. | Fluid transfer connector |
| US12447112B2 (en) | 2016-02-24 | 2025-10-21 | Avent, Inc. | Fluid transfer connector |
| JP2016209599A (ja) * | 2016-05-20 | 2016-12-15 | ライフ サイエンス エンタープライジズ インコーポレイテッド | リン酸カルシウム配合骨セメントを用いる脊椎骨の最小侵襲治療（ｍｉｔｖ） |
| US10150115B2 (en) * | 2016-07-21 | 2018-12-11 | Spacepharma SA | System and method for rehydrating powder and delivering the rehydrated powder to a reactor |
| USD833006S1 (en) | 2016-11-28 | 2018-11-06 | Neomed, Inc. | Fluid transfer connector |
| US10307548B1 (en) | 2016-12-14 | 2019-06-04 | Timothy Brandon Hunt | Tracking system and method for medical devices |
| US11097071B1 (en) | 2016-12-14 | 2021-08-24 | International Medical Industries Inc. | Tamper evident assembly |
| US10953162B1 (en) | 2016-12-28 | 2021-03-23 | Timothy Brandon Hunt | Tamper evident closure assembly |
| US10758684B1 (en) | 2017-03-03 | 2020-09-01 | Jonathan J. Vitello | Tamper evident assembly |
| DE102017104854B4 (de) * | 2017-03-08 | 2019-05-29 | Heraeus Medical Gmbh | Zweiteilige Lager- und Mischvorrichtung zur Herstellung eines Knochenzements und Verfahren hierzu |
| US11040149B1 (en) | 2017-03-30 | 2021-06-22 | International Medical Industries | Tamper evident closure assembly for a medical device |
| US10888672B1 (en) | 2017-04-06 | 2021-01-12 | International Medical Industries, Inc. | Tamper evident closure assembly for a medical device |
| DE102017107569A1 (de) | 2017-04-07 | 2018-10-11 | Heraeus Medical Gmbh | Vorrichtung zum Lagern, Vermischen und Austragen eines Knochenzements und Verfahren hierzu |
| US10933202B1 (en) | 2017-05-19 | 2021-03-02 | International Medical Industries Inc. | Indicator member of low strength resistance for a tamper evident closure |
| US10898659B1 (en) | 2017-05-19 | 2021-01-26 | International Medical Industries Inc. | System for handling and dispensing a plurality of products |
| US10575887B2 (en) | 2017-08-04 | 2020-03-03 | Medtronic Holding Company Sàrl | Dispensing system and methods of use |
| US11541180B1 (en) | 2017-12-21 | 2023-01-03 | Patrick Vitello | Closure assembly having a snap-fit construction |
| US11278681B1 (en) | 2018-02-20 | 2022-03-22 | Robert Banik | Tamper evident adaptor closure |
| US11413406B1 (en) | 2018-03-05 | 2022-08-16 | Jonathan J. Vitello | Tamper evident assembly |
| US11793987B1 (en) | 2018-07-02 | 2023-10-24 | Patrick Vitello | Flex tec closure assembly for a medical dispenser |
| US11857751B1 (en) | 2018-07-02 | 2024-01-02 | International Medical Industries Inc. | Assembly for a medical connector |
| US11779520B1 (en) | 2018-07-02 | 2023-10-10 | Patrick Vitello | Closure for a medical dispenser including a one-piece tip cap |
| US11690994B1 (en) | 2018-07-13 | 2023-07-04 | Robert Banik | Modular medical connector |
| US11426328B1 (en) | 2018-08-31 | 2022-08-30 | Alexander Ollmann | Closure for a medical container |
| US11471610B1 (en) | 2018-10-18 | 2022-10-18 | Robert Banik | Asymmetrical closure for a medical device |
| USD948713S1 (en) | 2019-09-03 | 2022-04-12 | International Medical Industries, Inc. | Asymmetrical self righting tip cap |
| USD903865S1 (en) | 2018-11-19 | 2020-12-01 | International Medical Industries, Inc. | Self-righting tip cap |
| US11911339B1 (en) | 2019-08-15 | 2024-02-27 | Peter Lehel | Universal additive port cap |
| US11697527B1 (en) | 2019-09-11 | 2023-07-11 | Logan Hendren | Tamper evident closure assembly |
| US11357588B1 (en) | 2019-11-25 | 2022-06-14 | Patrick Vitello | Needle packaging and disposal assembly |
| US11904149B1 (en) | 2020-02-18 | 2024-02-20 | Jonathan Vitello | Oral tamper evident closure with retained indicator |
| US11523970B1 (en) | 2020-08-28 | 2022-12-13 | Jonathan Vitello | Tamper evident shield |
| WO2022108017A1 (ko) * | 2020-11-20 | 2022-05-27 | (주) 메드파크 | 골 이식재 조성물 |
| US12070591B1 (en) | 2020-12-14 | 2024-08-27 | Patrick Vitello | Snap action tamper evident closure assembly |
| US11872187B1 (en) | 2020-12-28 | 2024-01-16 | Jonathan Vitello | Tamper evident seal for a vial cover |
| US12172803B1 (en) | 2021-10-04 | 2024-12-24 | Patrick Vitello | Tamper evident integrated closure |
Family Cites Families (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3770026A (en) * | 1971-09-17 | 1973-11-06 | J Isenberg | Apparatus and method for accurately loading syringes |
| US4551135A (en) * | 1981-06-22 | 1985-11-05 | Sterling Drug Inc. | Syringe for extrusion of semi-plastic material |
| DE8420774U1 (de) * | 1984-07-11 | 1985-09-12 | Draenert, Klaus, Dr.Med. Dr.Med.Habil., 8000 Muenchen | Vorrichtung zum Mischen und Applizieren von Knochenzement |
| US4743229A (en) * | 1986-09-29 | 1988-05-10 | Collagen Corporation | Collagen/mineral mixing device and method |
| US4919153A (en) | 1988-10-11 | 1990-04-24 | Origin Medsystems, Inc. | Method and apparatus for removing pre-placed prosthetic joints and preparing for their replacement |
| US4973168A (en) * | 1989-01-13 | 1990-11-27 | Chan Kwan Ho | Vacuum mixing/bone cement cartridge and kit |
| US5226877A (en) * | 1989-06-23 | 1993-07-13 | Epstein Gordon H | Method and apparatus for preparing fibrinogen adhesive from whole blood |
| DE9011685U1 (de) * | 1990-08-10 | 1991-12-12 | THERA Patent GmbH & Co. KG Gesellschaft für industrielle Schutzrechte, 82229 Seefeld | Granulatspritze |
| US5336699A (en) * | 1992-02-20 | 1994-08-09 | Orthopaedic Research Institute | Bone cement having chemically joined reinforcing fillers |
| US5676976A (en) | 1995-05-19 | 1997-10-14 | Etex Corporation | Synthesis of reactive amorphous calcium phosphates |
| US5783217A (en) | 1995-11-07 | 1998-07-21 | Etex Corporation | Low temperature calcium phosphate apatite and a method of its manufacture |
| US5902839A (en) * | 1996-12-02 | 1999-05-11 | Northwestern University | Bone cement and method of preparation |
| US7572263B2 (en) * | 1998-04-01 | 2009-08-11 | Arthrocare Corporation | High pressure applicator |
| JP2002532155A (ja) * | 1998-12-14 | 2002-10-02 | エーオー リサーチ インスティチュート ダフォス | 骨セメントの調製方法 |
| JP2003518411A (ja) * | 1999-12-29 | 2003-06-10 | リジェネレーション テクノロジーズ インク． | ペースト再構成のためのシステムおよびその使用法 |
| EP1303236B1 (en) * | 2000-07-14 | 2008-12-03 | Kyphon SARL | Systems for treating vertebral bodies |
| US6592251B2 (en) * | 2001-01-26 | 2003-07-15 | Howmedica Osteonics Corp. | Cement mixing and dispensing device |
| EP1441842A4 (en) * | 2001-10-09 | 2006-04-12 | Immedica | MULTI-COMPONENT PRODUCT HANDLING AND ADMINISTRATION SYSTEM |
| US6840961B2 (en) * | 2001-12-21 | 2005-01-11 | Etex Corporation | Machinable preformed calcium phosphate bone substitute material implants |
| AU2003228676A1 (en) | 2002-04-26 | 2003-11-10 | Surgical Sealants, Inc. | Mixing device for surgical sealants, and method thereof |
| US7776594B2 (en) * | 2002-10-10 | 2010-08-17 | Wright Medical Technology, Inc. | Bone marrow infusion chamber and method |
| ATE488205T1 (de) * | 2003-03-14 | 2010-12-15 | Depuy Spine Inc | Hydraulische vorrichtung zur knochenzementeinspritzung bei perkutaner vertebroplastie |
| WO2005069837A2 (en) | 2004-01-13 | 2005-08-04 | Royer Biomedical, Inc. | Non-aqueous compositions for treatment of orthopedic defects and delivery of bioactive agents |
| US20050209555A1 (en) * | 2004-03-18 | 2005-09-22 | Lance Middleton | Systems and methods for mixing fluids |
| JP2008504895A (ja) * | 2004-06-29 | 2008-02-21 | スパイン・ウェイブ・インコーポレーテッド | 椎間板の欠陥及び損傷を治療する方法 |
| US7329235B2 (en) * | 2004-08-02 | 2008-02-12 | Bertron Kim W | Powder and liquid mixing syringe |
| US8038682B2 (en) * | 2004-08-17 | 2011-10-18 | Boston Scientific Scimed, Inc. | Apparatus and methods for delivering compounds into vertebrae for vertebroplasty |
| SE530710C2 (sv) * | 2005-07-05 | 2008-08-19 | Biomet Cementing Technologies | Förfarande och anordning för att bringa en pulver- och en vätskekomponent, företrädesvis polymer och monomer, i kontakt med varandra för att blanda dessa, företrädesvis till bencement |
| US20070026030A1 (en) * | 2005-07-27 | 2007-02-01 | Berkeley Advanced Biomaterials, Inc. | Method of preparing rheological materials for bone and cartilage repair |
| US8641667B2 (en) * | 2005-10-20 | 2014-02-04 | DePuy Synthes Products, LLC | Perfusion device and method |
| US20070185495A1 (en) * | 2006-01-30 | 2007-08-09 | Howmedica International S. De R. L. | Plug-in syringe stand |
| KR101634664B1 (ko) | 2007-08-29 | 2016-06-29 | 에텍스 코포레이션 | 골 시멘트 혼합 및 전달 시스템 및 그의 사용 방법 |
-
2008
- 2008-08-28 KR KR1020107005678A patent/KR101634664B1/ko active Active
- 2008-08-28 US US12/675,455 patent/US9427715B2/en not_active Expired - Fee Related
- 2008-08-28 AU AU2008296990A patent/AU2008296990B2/en active Active
- 2008-08-28 CN CN200880105069A patent/CN101835434A/zh active Pending
- 2008-08-28 JP JP2010522956A patent/JP2010537718A/ja active Pending
- 2008-08-28 WO PCT/US2008/010214 patent/WO2009032173A1/en not_active Ceased
- 2008-08-28 CA CA2698017A patent/CA2698017C/en active Active
- 2008-08-28 CA CA2928681A patent/CA2928681C/en active Active
- 2008-08-28 EP EP08829040.8A patent/EP2200523B1/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| CA2928681C (en) | 2018-03-27 |
| US20110112543A1 (en) | 2011-05-12 |
| CA2698017A1 (en) | 2009-03-12 |
| CN101835434A (zh) | 2010-09-15 |
| KR20100061489A (ko) | 2010-06-07 |
| EP2200523A4 (en) | 2011-02-23 |
| EP2200523A1 (en) | 2010-06-30 |
| WO2009032173A1 (en) | 2009-03-12 |
| EP2200523B1 (en) | 2014-05-14 |
| CA2928681A1 (en) | 2009-03-12 |
| AU2008296990A1 (en) | 2009-03-12 |
| AU2008296990B2 (en) | 2014-12-18 |
| US9427715B2 (en) | 2016-08-30 |
| KR101634664B1 (ko) | 2016-06-29 |
| JP2010537718A (ja) | 2010-12-09 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CA2698017C (en) | Bone cement mixing and delivery system and methods of use thereof | |
| US8876911B2 (en) | Delivery device for biological composites and method of preparation thereof | |
| US6736799B1 (en) | Delivery device for biological composites and method of preparation thereof | |
| US5037445A (en) | Method and kit for molding surgical implants | |
| CA2438192C (en) | System for reconstituting pastes and methods of using same | |
| US20120071884A1 (en) | Mixing and dispensing apparatus for bone void filler | |
| EP3072538B1 (en) | Bioactive flowable wash-out resistant bone graft material and method for production thereof | |
| US8641667B2 (en) | Perfusion device and method | |
| JP2018143762A (ja) | 骨セメント製造用の二部構成の貯蔵および混合装置および関連の方法 | |
| JP2003527197A (ja) | 埋植材料用の調製および注入装置 | |
| CA2826628C (en) | Gelling collagen and means for providing same | |
| EP3043895A2 (en) | Dual component applicator | |
| WO2002040963A2 (en) | Biologically active composites and methods for their production and use | |
| US20210161572A1 (en) | Flowable bioactive bone void filler | |
| CN116251235A (zh) | 多孔骨引导/诱导自固化磷酸钙复合材料及其制备方法 | |
| AU2002250192A1 (en) | System for reconstituting pastes and methods of using same |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request |
Effective date: 20130823 |