CA2680481C - Intravesical apaziquone administration following transurethral resection for treating cancer - Google Patents

Intravesical apaziquone administration following transurethral resection for treating cancer Download PDF

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Publication number
CA2680481C
CA2680481C CA2680481A CA2680481A CA2680481C CA 2680481 C CA2680481 C CA 2680481C CA 2680481 A CA2680481 A CA 2680481A CA 2680481 A CA2680481 A CA 2680481A CA 2680481 C CA2680481 C CA 2680481C
Authority
CA
Canada
Prior art keywords
apaziquone
cancer
bladder
administration
transurethral resection
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA2680481A
Other languages
English (en)
French (fr)
Other versions
CA2680481A1 (en
Inventor
Luigi Lenaz
Shanta Chawla
Mario Beer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Spectrum Pharmaceuticals Inc
Original Assignee
Spectrum Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Spectrum Pharmaceuticals Inc filed Critical Spectrum Pharmaceuticals Inc
Publication of CA2680481A1 publication Critical patent/CA2680481A1/en
Application granted granted Critical
Publication of CA2680481C publication Critical patent/CA2680481C/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Dermatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CA2680481A 2007-03-13 2008-03-13 Intravesical apaziquone administration following transurethral resection for treating cancer Expired - Fee Related CA2680481C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US89461007P 2007-03-13 2007-03-13
US60/894,610 2007-03-13
PCT/US2008/056912 WO2008112934A1 (en) 2007-03-13 2008-03-13 Intravesical apaziquone administration following transurethral resection for treating cancer

Publications (2)

Publication Number Publication Date
CA2680481A1 CA2680481A1 (en) 2008-09-18
CA2680481C true CA2680481C (en) 2016-06-21

Family

ID=39494173

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2680481A Expired - Fee Related CA2680481C (en) 2007-03-13 2008-03-13 Intravesical apaziquone administration following transurethral resection for treating cancer

Country Status (17)

Country Link
US (1) US20080227841A1 (ru)
EP (1) EP2134322B1 (ru)
JP (2) JP5788143B2 (ru)
KR (1) KR20090128479A (ru)
CN (1) CN101677942B (ru)
AR (1) AR065732A1 (ru)
AU (1) AU2008224962B2 (ru)
BR (1) BRPI0808804A2 (ru)
CA (1) CA2680481C (ru)
ES (1) ES2727257T3 (ru)
IL (1) IL200899A0 (ru)
MX (1) MX2009009777A (ru)
NZ (1) NZ579609A (ru)
RU (2) RU2480200C2 (ru)
TW (1) TWI434684B (ru)
WO (1) WO2008112934A1 (ru)
ZA (1) ZA200906328B (ru)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201213486D0 (en) * 2012-07-30 2012-09-12 Univ Salford The Quinone compounds and their uses for the treatment of cancer
US9278124B2 (en) 2012-10-16 2016-03-08 Halozyme, Inc. Hypoxia and hyaluronan and markers thereof for diagnosis and monitoring of diseases and conditions and related methods

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2178305C1 (ru) * 2000-11-02 2002-01-20 Гарбер Александр Григорьевич Ирригационный раствор
AU2002350115A1 (en) * 2001-11-01 2003-05-12 Spectrum Pharmaceuticals, Inc. Medical compositions for intravesical treatment of bladder cancer
RU2002121829A (ru) * 2002-08-07 2004-02-27 Сгму Способ лечения местнораспространенных форм рака мочевого пузыря

Also Published As

Publication number Publication date
EP2134322B1 (en) 2019-02-20
TW200904410A (en) 2009-02-01
WO2008112934A1 (en) 2008-09-18
RU2012157329A (ru) 2014-07-10
NZ579609A (en) 2012-01-12
JP2010521488A (ja) 2010-06-24
ZA200906328B (en) 2010-05-26
RU2009137770A (ru) 2011-04-20
CN101677942B (zh) 2013-10-30
AU2008224962A1 (en) 2008-09-18
BRPI0808804A2 (pt) 2014-08-19
CA2680481A1 (en) 2008-09-18
JP5788143B2 (ja) 2015-09-30
AU2008224962B2 (en) 2013-07-25
IL200899A0 (en) 2010-05-17
AR065732A1 (es) 2009-06-24
US20080227841A1 (en) 2008-09-18
MX2009009777A (es) 2009-11-26
RU2480200C2 (ru) 2013-04-27
ES2727257T3 (es) 2019-10-15
TWI434684B (zh) 2014-04-21
RU2623142C2 (ru) 2017-06-22
EP2134322A1 (en) 2009-12-23
CN101677942A (zh) 2010-03-24
JP2014028841A (ja) 2014-02-13
KR20090128479A (ko) 2009-12-15

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Legal Events

Date Code Title Description
EEER Examination request

Effective date: 20130206

MKLA Lapsed

Effective date: 20210913

MKLA Lapsed

Effective date: 20200313