CA2679097C - Disposable tubing set for use with a cell expansion apparatus and method for sterile sampling - Google Patents
Disposable tubing set for use with a cell expansion apparatus and method for sterile sampling Download PDFInfo
- Publication number
- CA2679097C CA2679097C CA 2679097 CA2679097A CA2679097C CA 2679097 C CA2679097 C CA 2679097C CA 2679097 CA2679097 CA 2679097 CA 2679097 A CA2679097 A CA 2679097A CA 2679097 C CA2679097 C CA 2679097C
- Authority
- CA
- Canada
- Prior art keywords
- cellular
- area
- tube
- cellular growth
- growth area
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 230000010261 cell growth Effects 0.000 title claims abstract description 82
- 238000000034 method Methods 0.000 title claims description 16
- 238000005070 sampling Methods 0.000 title claims description 6
- 239000012530 fluid Substances 0.000 claims abstract description 61
- 230000001413 cellular effect Effects 0.000 claims abstract description 32
- 239000012528 membrane Substances 0.000 claims abstract description 19
- 238000004891 communication Methods 0.000 claims abstract description 16
- 150000001875 compounds Chemical class 0.000 claims description 12
- 238000013508 migration Methods 0.000 claims description 12
- 230000005012 migration Effects 0.000 claims description 12
- 238000007789 sealing Methods 0.000 claims description 6
- 210000004027 cell Anatomy 0.000 description 33
- 239000012510 hollow fiber Substances 0.000 description 14
- 239000007789 gas Substances 0.000 description 8
- 239000000835 fiber Substances 0.000 description 6
- 239000002699 waste material Substances 0.000 description 6
- 238000011072 cell harvest Methods 0.000 description 5
- 239000000463 material Substances 0.000 description 4
- 210000000130 stem cell Anatomy 0.000 description 4
- 239000004812 Fluorinated ethylene propylene Substances 0.000 description 3
- 238000002617 apheresis Methods 0.000 description 3
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 3
- 239000000306 component Substances 0.000 description 3
- 239000002874 hemostatic agent Substances 0.000 description 3
- 230000002503 metabolic effect Effects 0.000 description 3
- 229910052760 oxygen Inorganic materials 0.000 description 3
- 239000001301 oxygen Substances 0.000 description 3
- 229920009441 perflouroethylene propylene Polymers 0.000 description 3
- 230000002572 peristaltic effect Effects 0.000 description 3
- 239000004814 polyurethane Substances 0.000 description 3
- 229920000915 polyvinyl chloride Polymers 0.000 description 3
- 239000004800 polyvinyl chloride Substances 0.000 description 3
- 239000000047 product Substances 0.000 description 3
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 description 2
- JHIVVAPYMSGYDF-UHFFFAOYSA-N cyclohexanone Chemical compound O=C1CCCCC1 JHIVVAPYMSGYDF-UHFFFAOYSA-N 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 235000015097 nutrients Nutrition 0.000 description 2
- 239000002245 particle Substances 0.000 description 2
- 229920002635 polyurethane Polymers 0.000 description 2
- 230000001172 regenerating effect Effects 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 238000012546 transfer Methods 0.000 description 2
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 description 1
- 102000004127 Cytokines Human genes 0.000 description 1
- 108090000695 Cytokines Proteins 0.000 description 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
- JVTAAEKCZFNVCJ-UHFFFAOYSA-M Lactate Chemical compound CC(O)C([O-])=O JVTAAEKCZFNVCJ-UHFFFAOYSA-M 0.000 description 1
- 239000004952 Polyamide Substances 0.000 description 1
- 239000004698 Polyethylene Substances 0.000 description 1
- 239000003570 air Substances 0.000 description 1
- 244000000022 airborne pathogen Species 0.000 description 1
- 239000012080 ambient air Substances 0.000 description 1
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 239000006227 byproduct Substances 0.000 description 1
- 229910002092 carbon dioxide Inorganic materials 0.000 description 1
- 239000001569 carbon dioxide Substances 0.000 description 1
- 230000015556 catabolic process Effects 0.000 description 1
- 230000019522 cellular metabolic process Effects 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- HGAZMNJKRQFZKS-UHFFFAOYSA-N chloroethene;ethenyl acetate Chemical compound ClC=C.CC(=O)OC=C HGAZMNJKRQFZKS-UHFFFAOYSA-N 0.000 description 1
- 238000011109 contamination Methods 0.000 description 1
- 229910052802 copper Inorganic materials 0.000 description 1
- 239000010949 copper Substances 0.000 description 1
- 230000002950 deficient Effects 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 239000003792 electrolyte Substances 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- HQQADJVZYDDRJT-UHFFFAOYSA-N ethene;prop-1-ene Chemical group C=C.CC=C HQQADJVZYDDRJT-UHFFFAOYSA-N 0.000 description 1
- 239000012737 fresh medium Substances 0.000 description 1
- 239000008103 glucose Substances 0.000 description 1
- 230000012010 growth Effects 0.000 description 1
- 239000003102 growth factor Substances 0.000 description 1
- 210000002901 mesenchymal stem cell Anatomy 0.000 description 1
- 239000002207 metabolite Substances 0.000 description 1
- 229920000110 poly(aryl ether sulfone) Polymers 0.000 description 1
- 229920002647 polyamide Polymers 0.000 description 1
- -1 polyethylene Polymers 0.000 description 1
- 229920000573 polyethylene Polymers 0.000 description 1
- 229920000036 polyvinylpyrrolidone Polymers 0.000 description 1
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 description 1
- 239000001267 polyvinylpyrrolidone Substances 0.000 description 1
- 238000004382 potting Methods 0.000 description 1
- 230000037452 priming Effects 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 230000035755 proliferation Effects 0.000 description 1
- 230000008439 repair process Effects 0.000 description 1
- 230000010076 replication Effects 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 238000003466 welding Methods 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/42—Integrated assemblies, e.g. cassettes or cartridges
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M1/00—Apparatus for enzymology or microbiology
- C12M1/26—Inoculator or sampler
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/28—Constructional details, e.g. recesses, hinges disposable or single use
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/48—Holding appliances; Racks; Supports
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
- C12M29/04—Filters; Permeable or porous membranes or plates, e.g. dialysis
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M33/00—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Sustainable Development (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Clinical Laboratory Science (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US89246007P | 2007-03-01 | 2007-03-01 | |
| US60/892,460 | 2007-03-01 | ||
| US97138207P | 2007-09-11 | 2007-09-11 | |
| US60/971,382 | 2007-09-11 | ||
| PCT/US2008/052185 WO2008109200A1 (en) | 2007-03-01 | 2008-01-28 | Disposable tubing set for use with a cell expansion apparatus and method for sterile sampling |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2679097A1 CA2679097A1 (en) | 2008-09-12 |
| CA2679097C true CA2679097C (en) | 2015-04-28 |
Family
ID=39522125
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA 2679097 Expired - Fee Related CA2679097C (en) | 2007-03-01 | 2008-01-28 | Disposable tubing set for use with a cell expansion apparatus and method for sterile sampling |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US7718430B2 (enExample) |
| EP (1) | EP2115117A1 (enExample) |
| JP (1) | JP5149313B2 (enExample) |
| KR (1) | KR101440171B1 (enExample) |
| CN (1) | CN101622337B (enExample) |
| AU (1) | AU2008223280B2 (enExample) |
| CA (1) | CA2679097C (enExample) |
| WO (1) | WO2008109200A1 (enExample) |
Families Citing this family (50)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2115117A1 (en) * | 2007-03-01 | 2009-11-11 | CaridianBCT, Inc. | Disposable tubing set for use with a cell expansion apparatus and method for sterile sampling |
| EP2129764B1 (en) | 2007-03-05 | 2018-10-10 | Terumo BCT, Inc. | Cell expansion system and methods of use |
| US20080220522A1 (en) * | 2007-03-05 | 2008-09-11 | Gambro Bct, Inc. | Methods to Control Cell Movement in Hollow Fiber Bioreactors |
| US8999046B2 (en) | 2008-10-27 | 2015-04-07 | Terumo Bct, Inc. | Air removal chamber for a cell expansion system and method of use associated therewith |
| US9284523B2 (en) * | 2008-10-27 | 2016-03-15 | Terumo Bct, Inc. | Premounted fluid conveyance assembly for cell expansion system and method of use associated therewith |
| US8399245B2 (en) * | 2009-02-18 | 2013-03-19 | Terumo Bct, Inc. | Rotation system for cell growth chamber of a cell expansion system and method of use therefor |
| CA2757538A1 (en) * | 2009-04-03 | 2010-10-07 | Xcellerex, Inc. | Tissue and organ graft bioreactor and method of operation |
| GB0906836D0 (en) * | 2009-04-21 | 2009-06-03 | Cymtox Ltd | Consumable component kit |
| WO2011090605A2 (en) * | 2009-12-29 | 2011-07-28 | Caridianbct, Inc. | Method of loading and distributing cells in a bioreactor of a cell expansion system |
| US8539672B2 (en) * | 2010-10-01 | 2013-09-24 | Zevex, Inc. | Method for improving accuracy in a peristaltic pump system based on tubing material properties |
| US9725689B2 (en) | 2010-10-08 | 2017-08-08 | Terumo Bct, Inc. | Configurable methods and systems of growing and harvesting cells in a hollow fiber bioreactor system |
| WO2012168295A1 (en) | 2011-06-06 | 2012-12-13 | ReGenesys BVBA | Expansion of stem cells in hollow fiber bioreactors |
| DE102012200938B4 (de) | 2012-01-23 | 2016-08-18 | Alpha Plan Gmbh | Bio- und medizintechnisches Baukastensystem |
| US9175259B2 (en) * | 2012-08-20 | 2015-11-03 | Terumo Bct, Inc. | Method of loading and distributing cells in a bioreactor of a cell expansion system |
| JP2015526094A (ja) * | 2012-08-20 | 2015-09-10 | テルモ ビーシーティー、インコーポレーテッド | 細胞成長チャンバーを循環する流体の成分を濃縮する方法 |
| EP3068867B1 (en) | 2013-11-16 | 2018-04-18 | Terumo BCT, Inc. | Expanding cells in a bioreactor |
| US11008547B2 (en) | 2014-03-25 | 2021-05-18 | Terumo Bct, Inc. | Passive replacement of media |
| US10077421B2 (en) | 2014-04-24 | 2018-09-18 | Terumo Bct, Inc. | Measuring flow rate |
| EP3198006B1 (en) | 2014-09-26 | 2021-03-24 | Terumo BCT, Inc. | Scheduled feed |
| WO2017004592A1 (en) | 2015-07-02 | 2017-01-05 | Terumo Bct, Inc. | Cell growth with mechanical stimuli |
| CN105087380A (zh) * | 2015-07-31 | 2015-11-25 | 南方医科大学珠江医院 | 大规模培养动物细胞的系统 |
| GB201600315D0 (en) * | 2015-08-13 | 2016-02-24 | Gen Electric | Heatseal sampling |
| WO2017205667A1 (en) | 2016-05-25 | 2017-11-30 | Terumo Bct, Inc. | Cell expansion |
| US11104874B2 (en) | 2016-06-07 | 2021-08-31 | Terumo Bct, Inc. | Coating a bioreactor |
| US11685883B2 (en) | 2016-06-07 | 2023-06-27 | Terumo Bct, Inc. | Methods and systems for coating a cell growth surface |
| CN115044471B (zh) | 2016-08-27 | 2025-05-27 | 三维生物科技有限公司 | 生物反应器 |
| EP3565883A1 (en) | 2017-02-10 | 2019-11-13 | Lonza Ltd | Cell culture system and method |
| US11624046B2 (en) | 2017-03-31 | 2023-04-11 | Terumo Bct, Inc. | Cell expansion |
| JP7393945B2 (ja) | 2017-03-31 | 2023-12-07 | テルモ ビーシーティー、インコーポレーテッド | 細胞増殖 |
| US10696961B2 (en) | 2017-12-01 | 2020-06-30 | Global Life Sciences Solutions Usa Llc | Magnetic cell isolation techniques |
| US11932842B2 (en) | 2018-02-09 | 2024-03-19 | Global Life Sciences Solutions Usa Llc | Bioprocessing apparatus |
| US11414639B2 (en) | 2018-02-09 | 2022-08-16 | Global Life Sciences Solutions Usa Llc | Bioprocessing vessel |
| US12077743B2 (en) | 2018-02-09 | 2024-09-03 | Global Life Sciences Solutions Usa Llc | Apparatus for fluid line management in a bioprocessing system |
| US11920119B2 (en) | 2018-02-09 | 2024-03-05 | Global Life Sciences Solutions Usa Llc | Systems and methods for bioprocessing |
| SG11202007439TA (en) * | 2018-02-09 | 2020-09-29 | Global Life Sciences Solutions Usa Llc | Systems and methods for bioprocessing |
| US11371007B2 (en) | 2018-02-09 | 2022-06-28 | Global Life Sciences Solutions Usa Llc | System and method for fluid flow management in a bioprocessing system |
| US12252682B2 (en) | 2018-02-09 | 2025-03-18 | Global Life Sciences Solutions Usa Llc | System and method for fluid flow management in a bioprocessing system |
| US10889792B2 (en) | 2018-02-09 | 2021-01-12 | Global Life Sciences Solutions Usa Llc | Cell expansion vessel systems and methods |
| JP7225796B2 (ja) * | 2018-12-27 | 2023-02-21 | 大日本印刷株式会社 | サンプリング機能付き容器 |
| JP7638277B2 (ja) * | 2020-02-06 | 2025-03-03 | テルモ株式会社 | 流路カセット、細胞培養キット及び細胞培養システム |
| GB202017182D0 (en) | 2020-10-29 | 2020-12-16 | Cytiva Sweden Ab | Fluid coupling network for sampling a bioreactor |
| WO2023122133A1 (en) * | 2021-12-22 | 2023-06-29 | Pbs Biotech, Inc. | Apparatus and methods for treating media in large-scale bioreactors |
| US12599710B2 (en) | 2022-03-10 | 2026-04-14 | Terumo Bct, Inc. | Methods and interfaces for providing donation process feedback |
| US12653937B2 (en) | 2022-03-10 | 2026-06-16 | Terumo Bct, Inc. | Apheresis system safety features |
| US12521474B2 (en) | 2022-03-10 | 2026-01-13 | Terumo Bct, Inc. | Soft cassette with integrated features |
| US12691032B2 (en) | 2022-03-10 | 2026-07-28 | Terumo Bct, Inc. | Bottle tray with magnetic coupling and load cell overload protection |
| US12379916B2 (en) | 2022-03-10 | 2025-08-05 | Terumo Bct, Inc. | Communications and operation control of apheresis systems |
| US12458740B2 (en) | 2022-03-10 | 2025-11-04 | Terumo Bct, Inc. | Modular serviceability sleds and interconnections |
| US12478551B2 (en) | 2022-03-10 | 2025-11-25 | Terumo Bct, Inc. | Collection bottle with integrated cap, handle, and shield features |
| US20250304901A1 (en) * | 2024-03-26 | 2025-10-02 | Waters Technologies Corporation | Pneumatic transfer of fluid samples over lengthy conduits |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4889812A (en) * | 1986-05-12 | 1989-12-26 | C. D. Medical, Inc. | Bioreactor apparatus |
| JPH0576582A (ja) * | 1991-09-20 | 1993-03-30 | Hitachi Ltd | マイクロ波滅菌方法、その滅菌装置及び培養システム |
| EP1325110A4 (en) * | 2000-10-02 | 2009-03-25 | Thomas F Cannon | AUTOMATED BIOCULTURE AND BIOCULTURAL EXPERIENCE SYSTEM |
| US7198940B2 (en) * | 2000-10-25 | 2007-04-03 | Shot Hardware Optimization Technology, Inc. | Bioreactor apparatus and cell culturing system |
| WO2002087491A1 (en) | 2001-04-27 | 2002-11-07 | Baxter International Inc. | Sealing apparatus and method |
| JP4837893B2 (ja) * | 2001-12-10 | 2011-12-14 | カリディアンビーシーティー、インコーポレーテッド | 赤血球を白血球減少させる方法および装置 |
| US8492140B2 (en) * | 2002-04-08 | 2013-07-23 | Octane Biotech Inc. | Automated tissue engineering system |
| US20040009542A1 (en) * | 2002-05-03 | 2004-01-15 | Gambro, Inc. | Apparatus and method for detecting bacteria in blood products |
| JP4668568B2 (ja) * | 2003-08-26 | 2011-04-13 | 株式会社メディネット | 培養容器、培養装置および細胞の培養方法 |
| WO2006026835A1 (en) * | 2004-09-10 | 2006-03-16 | Unisearch Limited | Device and method to prevent culture media degradation |
| JP2008539738A (ja) * | 2005-05-09 | 2008-11-20 | サクソニア バイオテック ゲーエムベーハー | 細胞培養モジュール用供給システム |
| EP2115117A1 (en) | 2007-03-01 | 2009-11-11 | CaridianBCT, Inc. | Disposable tubing set for use with a cell expansion apparatus and method for sterile sampling |
-
2008
- 2008-01-28 EP EP08728380A patent/EP2115117A1/en not_active Withdrawn
- 2008-01-28 JP JP2009551768A patent/JP5149313B2/ja not_active Expired - Fee Related
- 2008-01-28 WO PCT/US2008/052185 patent/WO2008109200A1/en not_active Ceased
- 2008-01-28 AU AU2008223280A patent/AU2008223280B2/en not_active Ceased
- 2008-01-28 US US12/021,013 patent/US7718430B2/en not_active Expired - Fee Related
- 2008-01-28 CA CA 2679097 patent/CA2679097C/en not_active Expired - Fee Related
- 2008-01-28 KR KR1020097020706A patent/KR101440171B1/ko not_active Expired - Fee Related
- 2008-01-28 CN CN2008800067945A patent/CN101622337B/zh not_active Expired - Fee Related
-
2010
- 2010-02-16 US US12/706,380 patent/US8163555B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| WO2008109200A1 (en) | 2008-09-12 |
| US8163555B2 (en) | 2012-04-24 |
| CN101622337A (zh) | 2010-01-06 |
| CN101622337B (zh) | 2013-04-24 |
| JP2010519903A (ja) | 2010-06-10 |
| CA2679097A1 (en) | 2008-09-12 |
| KR20090121372A (ko) | 2009-11-25 |
| AU2008223280A1 (en) | 2008-09-12 |
| US7718430B2 (en) | 2010-05-18 |
| KR101440171B1 (ko) | 2014-09-15 |
| US20100144037A1 (en) | 2010-06-10 |
| EP2115117A1 (en) | 2009-11-11 |
| JP5149313B2 (ja) | 2013-02-20 |
| US20080213894A1 (en) | 2008-09-04 |
| AU2008223280B2 (en) | 2013-09-19 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US7718430B2 (en) | Disposable tubing set for use with a cell expansion apparatus and method for sterile sampling | |
| US20080227190A1 (en) | Cell Expansion Apparatus with Plate Bioreactor | |
| JP7362812B2 (ja) | 交互接線流の使い捨て濾過ユニット | |
| US8906688B2 (en) | Cell expansion system and methods of use | |
| US10022487B2 (en) | Single collection bag blood collection system, method and apparatus | |
| JP2020528284A5 (enExample) | ||
| JPS62171669A (ja) | 細胞を培養し、老廃物を取出し、生産物を濃縮する装置および方法 | |
| CN101321856A (zh) | 用于细胞培养模块的供应系统 | |
| CN113498432A (zh) | 用于自动化生物反应器的细胞浓缩方法和装置 | |
| EP2566950B1 (en) | Method and apparatus for controlling a cell expansion apparatus | |
| US20240287439A1 (en) | Systems and methods for manufacturing cells | |
| KR20230119680A (ko) | 바이오 처리 시스템용 배양 용기 | |
| KR20230119645A (ko) | 세포 농축, 단리 및 제형화를 위한 시스템 및 방법 | |
| KR20230119644A (ko) | 바이오 처리 시스템 및 방법 | |
| WO2018129467A1 (en) | Devices and methods for bio-processing cellular samples | |
| HK40051570A (en) | Cell concentration methods and devices for use in automated bioreactors |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| MKLA | Lapsed |
Effective date: 20200128 |