CN101622337B - 用于与细胞扩增装置一起使用的一次性管道成套设备和无菌取样的方法 - Google Patents

用于与细胞扩增装置一起使用的一次性管道成套设备和无菌取样的方法 Download PDF

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Publication number
CN101622337B
CN101622337B CN2008800067945A CN200880006794A CN101622337B CN 101622337 B CN101622337 B CN 101622337B CN 2008800067945 A CN2008800067945 A CN 2008800067945A CN 200880006794 A CN200880006794 A CN 200880006794A CN 101622337 B CN101622337 B CN 101622337B
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fluid
growth area
cellular growth
feed region
sample
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Expired - Fee Related
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Chinese (zh)
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CN101622337A (zh
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G·D·安特韦勒
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Terumo BCT Inc
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Terumo BCT Inc
Gambro BCT Inc
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/42—Integrated assemblies, e.g. cassettes or cartridges
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M1/00—Apparatus for enzymology or microbiology
    • C12M1/26—Inoculator or sampler
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/28—Constructional details, e.g. recesses, hinges disposable or single use
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/48—Holding appliances; Racks; Supports
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/04—Filters; Permeable or porous membranes or plates, e.g. dialysis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M33/00—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Sustainable Development (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Clinical Laboratory Science (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
CN2008800067945A 2007-03-01 2008-01-28 用于与细胞扩增装置一起使用的一次性管道成套设备和无菌取样的方法 Expired - Fee Related CN101622337B (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US89246007P 2007-03-01 2007-03-01
US60/892,460 2007-03-01
US97138207P 2007-09-11 2007-09-11
US60/971,382 2007-09-11
PCT/US2008/052185 WO2008109200A1 (en) 2007-03-01 2008-01-28 Disposable tubing set for use with a cell expansion apparatus and method for sterile sampling

Publications (2)

Publication Number Publication Date
CN101622337A CN101622337A (zh) 2010-01-06
CN101622337B true CN101622337B (zh) 2013-04-24

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CN2008800067945A Expired - Fee Related CN101622337B (zh) 2007-03-01 2008-01-28 用于与细胞扩增装置一起使用的一次性管道成套设备和无菌取样的方法

Country Status (8)

Country Link
US (2) US7718430B2 (enExample)
EP (1) EP2115117A1 (enExample)
JP (1) JP5149313B2 (enExample)
KR (1) KR101440171B1 (enExample)
CN (1) CN101622337B (enExample)
AU (1) AU2008223280B2 (enExample)
CA (1) CA2679097C (enExample)
WO (1) WO2008109200A1 (enExample)

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WO2012048298A2 (en) 2010-10-08 2012-04-12 Caridianbct, Inc. Methods and systems of growing and harvesting cells in a hollow fiber bioreactor system with control conditions
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US9175259B2 (en) * 2012-08-20 2015-11-03 Terumo Bct, Inc. Method of loading and distributing cells in a bioreactor of a cell expansion system
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US11008547B2 (en) 2014-03-25 2021-05-18 Terumo Bct, Inc. Passive replacement of media
US10077421B2 (en) 2014-04-24 2018-09-18 Terumo Bct, Inc. Measuring flow rate
WO2016049421A1 (en) 2014-09-26 2016-03-31 Terumo Bct, Inc. Scheduled feed
WO2017004592A1 (en) 2015-07-02 2017-01-05 Terumo Bct, Inc. Cell growth with mechanical stimuli
CN105087380A (zh) * 2015-07-31 2015-11-25 南方医科大学珠江医院 大规模培养动物细胞的系统
GB201600315D0 (en) * 2015-08-13 2016-02-24 Gen Electric Heatseal sampling
US11965175B2 (en) 2016-05-25 2024-04-23 Terumo Bct, Inc. Cell expansion
US11685883B2 (en) 2016-06-07 2023-06-27 Terumo Bct, Inc. Methods and systems for coating a cell growth surface
US11104874B2 (en) 2016-06-07 2021-08-31 Terumo Bct, Inc. Coating a bioreactor
CN115044471B (zh) 2016-08-27 2025-05-27 三维生物科技有限公司 生物反应器
US11559811B2 (en) 2017-02-10 2023-01-24 Lonza Ltd. Cell culture system and method
US11629332B2 (en) 2017-03-31 2023-04-18 Terumo Bct, Inc. Cell expansion
US11624046B2 (en) 2017-03-31 2023-04-11 Terumo Bct, Inc. Cell expansion
US10696961B2 (en) 2017-12-01 2020-06-30 Global Life Sciences Solutions Usa Llc Magnetic cell isolation techniques
US11371007B2 (en) 2018-02-09 2022-06-28 Global Life Sciences Solutions Usa Llc System and method for fluid flow management in a bioprocessing system
US12077743B2 (en) 2018-02-09 2024-09-03 Global Life Sciences Solutions Usa Llc Apparatus for fluid line management in a bioprocessing system
US12252682B2 (en) 2018-02-09 2025-03-18 Global Life Sciences Solutions Usa Llc System and method for fluid flow management in a bioprocessing system
US10889792B2 (en) 2018-02-09 2021-01-12 Global Life Sciences Solutions Usa Llc Cell expansion vessel systems and methods
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JP7314151B2 (ja) * 2018-02-09 2023-07-25 グローバル・ライフ・サイエンシズ・ソリューションズ・ユーエスエー・エルエルシー バイオプロセッシングのための使い捨てキット
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WO2023122133A1 (en) * 2021-12-22 2023-06-29 Pbs Biotech, Inc. Apparatus and methods for treating media in large-scale bioreactors
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US12478551B2 (en) 2022-03-10 2025-11-25 Terumo Bct, Inc. Collection bottle with integrated cap, handle, and shield features
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Publication number Publication date
CA2679097C (en) 2015-04-28
CN101622337A (zh) 2010-01-06
JP2010519903A (ja) 2010-06-10
US8163555B2 (en) 2012-04-24
WO2008109200A1 (en) 2008-09-12
AU2008223280B2 (en) 2013-09-19
KR101440171B1 (ko) 2014-09-15
US7718430B2 (en) 2010-05-18
US20100144037A1 (en) 2010-06-10
CA2679097A1 (en) 2008-09-12
JP5149313B2 (ja) 2013-02-20
KR20090121372A (ko) 2009-11-25
US20080213894A1 (en) 2008-09-04
EP2115117A1 (en) 2009-11-11
AU2008223280A1 (en) 2008-09-12

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Applicant after: TERUMO BCT, Inc.

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Applicant before: GAMBRO BCT, Inc.

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