CA2676843A1 - Method for producing novel ige based reagents - Google Patents

Method for producing novel ige based reagents Download PDF

Info

Publication number
CA2676843A1
CA2676843A1 CA002676843A CA2676843A CA2676843A1 CA 2676843 A1 CA2676843 A1 CA 2676843A1 CA 002676843 A CA002676843 A CA 002676843A CA 2676843 A CA2676843 A CA 2676843A CA 2676843 A1 CA2676843 A1 CA 2676843A1
Authority
CA
Canada
Prior art keywords
protein
binding
ige
ligand
antibody
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002676843A
Other languages
English (en)
French (fr)
Inventor
Kristiina Takkinen
Juha Rouvinen
Merja Niemi
Sirpa Jylhae
Marja-Leena Laukkanen
Hans Soederlund
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
DESENTUM Oy
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FI20075059A external-priority patent/FI20075059A0/fi
Priority claimed from FI20075707A external-priority patent/FI20075707A0/fi
Application filed by Individual filed Critical Individual
Publication of CA2676843A1 publication Critical patent/CA2676843A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • CCHEMISTRY; METALLURGY
    • C40COMBINATORIAL TECHNOLOGY
    • C40BCOMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B30/00Methods of screening libraries
    • C40B30/04Methods of screening libraries by measuring the ability to specifically bind a target molecule, e.g. antibody-antigen binding, receptor-ligand binding
    • CCHEMISTRY; METALLURGY
    • C40COMBINATORIAL TECHNOLOGY
    • C40BCOMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00Libraries per se, e.g. arrays, mixtures
    • C40B40/04Libraries containing only organic compounds
    • C40B40/10Libraries containing peptides or polypeptides, or derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/60Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/622Single chain antibody (scFv)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
CA002676843A 2007-01-29 2008-01-29 Method for producing novel ige based reagents Abandoned CA2676843A1 (en)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
FI20075059A FI20075059A0 (fi) 2007-01-29 2007-01-29 Allergeeniä sitovat monoklonaaliset IgE-vasta-aineet ja hypoallergeenit:tyypin l lgE:n ja allergeenin immunokompleksivuorovaikutus
FI20075059 2007-01-29
US88786207P 2007-02-02 2007-02-02
US60/887,862 2007-02-02
US97788107P 2007-10-05 2007-10-05
FI20075707 2007-10-05
US60/977,881 2007-10-05
FI20075707A FI20075707A0 (fi) 2007-10-05 2007-10-05 Menetelmä uusien IgE-pohjaisten reagenssien valmistamiseksi
PCT/FI2008/050027 WO2008092993A1 (en) 2007-01-29 2008-01-29 Method for producing novel ige based reagents

Publications (1)

Publication Number Publication Date
CA2676843A1 true CA2676843A1 (en) 2008-08-07

Family

ID=39673692

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002676843A Abandoned CA2676843A1 (en) 2007-01-29 2008-01-29 Method for producing novel ige based reagents

Country Status (7)

Country Link
US (1) US20100311604A1 (enExample)
EP (1) EP2115139B8 (enExample)
JP (1) JP2010516747A (enExample)
AU (1) AU2008211807B2 (enExample)
CA (1) CA2676843A1 (enExample)
NZ (1) NZ577858A (enExample)
WO (1) WO2008092993A1 (enExample)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011156734A2 (en) 2010-06-11 2011-12-15 Hitachi Chemical Co., Ltd. Method of characterizing vascular diseases
JP5755326B2 (ja) * 2010-06-11 2015-07-29 日立化成株式会社 腎機能の特徴を決定する方法
WO2012170037A1 (en) 2011-06-10 2012-12-13 Hitachi Chemical Co., Ltd. Vesicle capturing devices and methods for using same
JP6232618B2 (ja) 2012-06-28 2017-11-22 国立大学法人広島大学 ヒト汗中に含まれる新規ヒスタミン遊離物質
US9989538B2 (en) 2012-08-17 2018-06-05 Hiroshima University Monoclonal IgE antibody that binds to sweat allergy antigen protein
WO2014182330A1 (en) 2013-05-06 2014-11-13 Hitachi Chemical Company Ltd Devices and methods for capturing target molecules
EP2820947A1 (en) * 2013-07-05 2015-01-07 B Cell Design Transgenic non-human mammal for producing chimeric human immunoglobulin E antibodies
US10266895B2 (en) 2014-11-05 2019-04-23 Hitachi Chemical Company Ltd. Exosomes and microvesicles in intestinal luminal fluids and stool and use of same for the assessment of inflammatory bowel disease
WO2016077537A1 (en) 2014-11-12 2016-05-19 Hitachi Chemical Co., Ltd. Method and device for diagnosing organ injury
US11028443B2 (en) 2015-08-31 2021-06-08 Showa Denko Materials Co., Ltd. Molecular methods for assessing urothelial disease
TW202409084A (zh) 2016-03-04 2024-03-01 美商Jn生物科學有限責任公司 針對tigit之抗體
JP2020508697A (ja) * 2017-01-31 2020-03-26 エム・エス・エム・プロテイン・テクノロジーズ・インコーポレイテッド 抗cxcr4抗体
KR20230019152A (ko) 2020-06-02 2023-02-07 아르커스 바이오사이언시즈 인코포레이티드 Tigit에 대한 항체
CN119626432B (zh) * 2025-02-17 2025-05-27 杭州艾替捷英科技有限公司 针对宠物过敏源检测结果大数据的云架构聚类管理方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2059842A1 (en) * 1991-02-11 1992-08-12 Richard A. Chizzonite Ige-receptor-antibodies
US5965709A (en) * 1991-08-14 1999-10-12 Genentech, Inc. IgE antagonists
US6063621A (en) * 1992-10-27 2000-05-16 Queen's University At Kingston Antibodies to a multidrug resistance protein
ZA966075B (en) * 1995-07-27 1998-01-19 Genentech Inc Protein formulation.
US6299875B1 (en) * 1998-06-04 2001-10-09 Panacea Pharmaceuticals, Llc Methods to block IGE binding to cell surface receptors of mast cells
FI112501B (fi) * 2001-05-18 2003-12-15 Valtion Teknillinen Heveiiniä sitovat monoklonaaliset vasta-aineet
US7438907B2 (en) * 2002-11-15 2008-10-21 Genmab A/S Human monoclonal antibodies against CD25
JP2005024245A (ja) * 2003-03-25 2005-01-27 Rikogaku Shinkokai Abcタンパク質と相互作用する物質のスクリーニング方法
WO2005051299A2 (en) * 2003-11-19 2005-06-09 Dyax Corp. Metalloproteinase-binding proteins

Also Published As

Publication number Publication date
JP2010516747A (ja) 2010-05-20
EP2115139A1 (en) 2009-11-11
AU2008211807B2 (en) 2013-09-19
EP2115139B1 (en) 2015-01-28
EP2115139B8 (en) 2015-03-18
EP2115139A4 (en) 2011-03-23
WO2008092993A1 (en) 2008-08-07
NZ577858A (en) 2012-02-24
AU2008211807A1 (en) 2008-08-07
US20100311604A1 (en) 2010-12-09

Similar Documents

Publication Publication Date Title
AU2008211807B2 (en) Method for producing novel IgE based reagents
Huston et al. Engineered antibodies take center stage
JP4477579B2 (ja) 抗体の軽鎖スクリーニング方法
CN103201293B (zh) 评估和鉴定或发展条件活性治疗蛋白的方法
US8241858B2 (en) Rapid, sensitive and quantitative methods for tissue and cell-based proteomics via consecutive addition of quantifiable extenders
JP2010516747A5 (enExample)
WO2008054030A1 (fr) Peptide liant l'igg
DK2114996T3 (en) A process for the preparation of hypo allergens
EP1918302A2 (en) Methods for the identification and the isolation of epitope specific antibodies
EP2262835A1 (en) Immunoglobulin compositions and methods of producing same
Hemmi et al. Construction of a circularly connected VHH bispecific antibody (cyclobody) for the desirable positioning of antigen-binding sites
CN109336973B (zh) 抗转铁蛋白抗体及其用途
CN110642947A (zh) 抗人cd147的单克隆抗体、表达载体、细胞株及其应用
Alvarenga et al. Recombinant antibodies: trends for standardized immunological probes and drugs
US20050118161A1 (en) Hevein-binding monoclonal antibodies
JP2024523921A (ja) 特異的バインダーの選択手段及び方法
CN105683755B (zh) 陷阱分子和检测分子的用途及其相关试剂盒和组合物
CN113999306B (zh) 一种获得识别空间构象表位抗体的方法
Hammond et al. Isolation of antibodies which neutralise the activity of early pregnancy factor
Kramer et al. Antibodies for biosensors
CN117836308A (zh) 用于选择特异性结合剂的手段和方法
DE PONT Max Planck Institute for Biophysics
Shibui et al. Mimotopes to Cetuximab Isolated by mRNA-Display using Random Peptide Libraries and their Characteristics
Economopoulos The Generation of Affinity Reagents Using High-throughput Phage Display and Building the Foundations of a Novel High-throughput Intrabody Pipeline
Klagge Generation and Screening of the Synthetic Human Combinatorial Antibody Library HuCAL GOLD

Legal Events

Date Code Title Description
EEER Examination request

Effective date: 20130115

FZDE Dead

Effective date: 20161121