CA2676119C - Transvascular nerve stimulation apparatus and methods - Google Patents

Transvascular nerve stimulation apparatus and methods Download PDF

Info

Publication number
CA2676119C
CA2676119C CA2676119A CA2676119A CA2676119C CA 2676119 C CA2676119 C CA 2676119C CA 2676119 A CA2676119 A CA 2676119A CA 2676119 A CA2676119 A CA 2676119A CA 2676119 C CA2676119 C CA 2676119C
Authority
CA
Canada
Prior art keywords
electrodes
stimulation
nerve
electrode
pairs
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA2676119A
Other languages
English (en)
French (fr)
Other versions
CA2676119A1 (en
Inventor
Joaquin Andres Hoffer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Lungpacer Medical Inc
Original Assignee
Lungpacer Medical Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lungpacer Medical Inc filed Critical Lungpacer Medical Inc
Priority to CA2877177A priority Critical patent/CA2877177C/en
Publication of CA2676119A1 publication Critical patent/CA2676119A1/en
Application granted granted Critical
Publication of CA2676119C publication Critical patent/CA2676119C/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/3606—Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
    • A61N1/3611—Respiration control
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
    • A61N1/0551—Spinal or peripheral nerve electrodes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
    • A61N1/0551—Spinal or peripheral nerve electrodes
    • A61N1/0558—Anchoring or fixation means therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3601—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation of respiratory organs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/36128—Control systems
    • A61N1/36135—Control systems using physiological parameters
    • A61N1/36139—Control systems using physiological parameters with automatic adjustment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/36128—Control systems
    • A61N1/36146—Control systems specified by the stimulation parameters
    • A61N1/36182—Direction of the electrical field, e.g. with sleeve around stimulating electrode
    • A61N1/36185—Selection of the electrode configuration

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pulmonology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physiology (AREA)
  • Biophysics (AREA)
  • Electrotherapy Devices (AREA)
CA2676119A 2007-01-29 2008-01-29 Transvascular nerve stimulation apparatus and methods Active CA2676119C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA2877177A CA2877177C (en) 2007-01-29 2008-01-29 Transvascular nerve stimulation apparatus and methods

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US88703107P 2007-01-29 2007-01-29
US60/887,031 2007-01-29
PCT/CA2008/000179 WO2008092246A1 (en) 2007-01-29 2008-01-29 Transvascular nerve stimulation apparatus and methods

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CA2877177A Division CA2877177C (en) 2007-01-29 2008-01-29 Transvascular nerve stimulation apparatus and methods

Publications (2)

Publication Number Publication Date
CA2676119A1 CA2676119A1 (en) 2008-08-07
CA2676119C true CA2676119C (en) 2021-01-19

Family

ID=39673597

Family Applications (3)

Application Number Title Priority Date Filing Date
CA2676119A Active CA2676119C (en) 2007-01-29 2008-01-29 Transvascular nerve stimulation apparatus and methods
CA3000408A Active CA3000408C (en) 2007-01-29 2008-01-29 Transvascular nerve stimulation apparatus and methods
CA2877177A Active CA2877177C (en) 2007-01-29 2008-01-29 Transvascular nerve stimulation apparatus and methods

Family Applications After (2)

Application Number Title Priority Date Filing Date
CA3000408A Active CA3000408C (en) 2007-01-29 2008-01-29 Transvascular nerve stimulation apparatus and methods
CA2877177A Active CA2877177C (en) 2007-01-29 2008-01-29 Transvascular nerve stimulation apparatus and methods

Country Status (7)

Country Link
US (17) US8571662B2 (enExample)
EP (1) EP2107920B1 (enExample)
JP (1) JP5465538B2 (enExample)
CA (3) CA2676119C (enExample)
DK (1) DK2107920T3 (enExample)
ES (1) ES2430613T3 (enExample)
WO (1) WO2008092246A1 (enExample)

Families Citing this family (93)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7480532B2 (en) 2003-10-22 2009-01-20 Cvrx, Inc. Baroreflex activation for pain control, sedation and sleep
US12179014B2 (en) 2005-11-18 2024-12-31 Zoll Respicardia, Inc. Transvenous phrenic nerve stimulation system
US10406366B2 (en) 2006-11-17 2019-09-10 Respicardia, Inc. Transvenous phrenic nerve stimulation system
WO2007061902A2 (en) 2005-11-18 2007-05-31 Cardiac Concepts System and method to modulate phrenic nerve to prevent sleep apnea
JP5256048B2 (ja) * 2006-02-03 2013-08-07 シネコー・エルエルシー 神経調節のための脈管内デバイス
US8909341B2 (en) 2007-01-22 2014-12-09 Respicardia, Inc. Device and method for the treatment of breathing disorders and cardiac disorders
CA2676119C (en) 2007-01-29 2021-01-19 Simon Fraser University Transvascular nerve stimulation apparatus and methods
US9987488B1 (en) 2007-06-27 2018-06-05 Respicardia, Inc. Detecting and treating disordered breathing
US9199075B1 (en) 2008-02-07 2015-12-01 Respicardia, Inc. Transvascular medical lead
US7925352B2 (en) 2008-03-27 2011-04-12 Synecor Llc System and method for transvascularly stimulating contents of the carotid sheath
US9889299B2 (en) 2008-10-01 2018-02-13 Inspire Medical Systems, Inc. Transvenous method of treating sleep apnea
EP2364178A1 (en) 2008-10-13 2011-09-14 E- Pacing, Inc. Devices and methods for electrical stimulation of the diaphragm and nerves
US8478423B2 (en) 2009-04-07 2013-07-02 Boston Scientific Neuromodulation Corporation Insulator layers for leads of implantable electric stimulation systems and methods of making and using
AU2010254490B2 (en) * 2009-05-26 2014-06-12 Cardiac Pacemakers, Inc. Helically formed coil for a neural cuff electrode
US8233987B2 (en) 2009-09-10 2012-07-31 Respicardia, Inc. Respiratory rectification
US9468755B2 (en) * 2009-09-30 2016-10-18 Respicardia, Inc. Medical lead with preformed bias
US8620428B2 (en) * 2009-12-17 2013-12-31 Cardiac Pacemakers, Inc. Electrical inibition of the phrenic nerve during cardiac pacing
US9050453B2 (en) 2010-03-19 2015-06-09 National Cerebral And Cardiovascular Center Electrostimulation system, and electrostimulation electrode assembly and biological implantable electrode therefore
JP5624779B2 (ja) * 2010-03-19 2014-11-12 オリンパス株式会社 電気刺激システム
JP5537213B2 (ja) * 2010-03-26 2014-07-02 オリンパス株式会社 電気刺激電極組立体
US20130018444A1 (en) * 2011-07-11 2013-01-17 Glenn Richard A Intravascular electrodes for transvascular stimulation
WO2012149511A2 (en) 2011-04-28 2012-11-01 Synecor Llc Neuromodulation systems and methods for treating acute heart failure syndromes
EP3002037B1 (en) 2010-09-15 2018-06-06 Cardiac Pacemakers, Inc. Automatic selection of lead configuration for a neural stimulation lead
US20120095371A1 (en) 2010-10-18 2012-04-19 CardioSonic Ltd. Ultrasound transducer and cooling thereof
WO2012052925A1 (en) 2010-10-18 2012-04-26 CardioSonic Ltd. An ultrasound transceiver and control of a thermal damage process
US10569083B2 (en) 2010-11-11 2020-02-25 IINN, Inc. Motor devices for motor nerve root stimulation
EP2651431B1 (en) * 2010-12-17 2018-03-07 Neural Diabetes LLC System and apparatus for control of pancreatic beta cell function to improve glucose homeostatis and insulin production
US8909316B2 (en) 2011-05-18 2014-12-09 St. Jude Medical, Cardiology Division, Inc. Apparatus and method of assessing transvascular denervation
US8996114B2 (en) 2011-06-28 2015-03-31 Cardiac Pacemakers, Inc. Strain relief feature for an implantable medical device lead
US8639355B2 (en) 2011-07-07 2014-01-28 Cardiac Pacemakers, Inc. Insulation and stability features for an implantable medical device lead
US20130072995A1 (en) 2011-07-11 2013-03-21 Terrance Ransbury Catheter system for acute neuromodulation
WO2013022543A2 (en) 2011-07-11 2013-02-14 Synecor Llc Catheter system for acute neuromodulation
US9446240B2 (en) 2011-07-11 2016-09-20 Interventional Autonomics Corporation System and method for neuromodulation
EP2793996B1 (en) 2011-12-21 2016-02-24 Cardiac Pacemakers, Inc. Directional features for implantable medical leads
IN2014MN01970A (enExample) * 2012-03-05 2015-07-03 Univ Fraser Simon
RU2644933C2 (ru) * 2012-03-08 2018-02-14 Медтроник Аф Люксембург Сарл Отбор образцов биомаркеров в контексте устройств для нейромодуляции и соответствующие системы и способы
US8903509B2 (en) 2012-03-21 2014-12-02 Cardiac Pacemakers Inc. Systems and methods for stimulation of vagus nerve
WO2013157011A2 (en) 2012-04-18 2013-10-24 CardioSonic Ltd. Tissue treatment
US11395921B2 (en) 2012-04-29 2022-07-26 Nuxcel2 Llc Intravascular electrode arrays for neuromodulation
WO2013165920A1 (en) * 2012-04-29 2013-11-07 Synecor Llc Intravascular electrode arrays for neuromodulation
US11357447B2 (en) 2012-05-31 2022-06-14 Sonivie Ltd. Method and/or apparatus for measuring renal denervation effectiveness
AU2013280184B2 (en) * 2012-06-21 2017-08-24 Lungpacer Medical Inc. Transvascular diaphragm pacing systems and methods of use
US9283379B2 (en) 2012-10-02 2016-03-15 Cardiac Pacemakers, Inc. Pinch to open cuff electrode
JP6096300B2 (ja) 2012-10-02 2017-03-15 カーディアック ペースメイカーズ， インコーポレイテッド カフ電極アセンブリおよびリードアセンブリ
EP2938396B1 (en) 2012-12-28 2017-02-22 Cardiac Pacemakers, Inc. Stimulation cuff and implantation tool
JP6069523B2 (ja) 2013-02-13 2017-02-01 カーディアック ペースメイカーズ， インコーポレイテッド 一体型つる状体を備えたカフ電極
JP6212814B2 (ja) * 2013-05-21 2017-10-18 国立研究開発法人科学技術振興機構 多点プローブ及びそれを構成する電子接点シート、多点プローブアレイ並びに多点プローブの製造方法
US10933259B2 (en) 2013-05-23 2021-03-02 CardioSonic Ltd. Devices and methods for renal denervation and assessment thereof
EP3760276B1 (en) * 2013-11-22 2023-08-30 Lungpacer Medical Inc. Apparatus for assisted breathing by transvascular nerve stimulation
WO2015109401A1 (en) 2014-01-21 2015-07-30 Simon Fraser University Systems and related methods for optimization of multi-electrode nerve pacing
AU2015229669A1 (en) * 2014-03-09 2016-09-29 Neuro Tronik Ip Holding (Jersey) Limited Systems and methods for neuromodulation of sympathetic and parasympathetic cardiac nerves
US12070601B2 (en) 2014-03-28 2024-08-27 Pinnacle Bionics. Inc. Stimulation system for exercising diaphragm and method of operation thereof
EP2959938B1 (fr) * 2014-06-25 2017-03-22 Sorin CRM SAS Sonde implantable comprenant un manchon enroulable autour d'un organe tel qu'un nerf
US20170312525A1 (en) * 2014-08-06 2017-11-02 NeuroTronik IP Holding (Jersey) Limited Systems and methods for neuromodulation of sympathetic and parasympathetic cardiac nerves
JP2017523849A (ja) * 2014-08-06 2017-08-24 ニューロトロニク アイ・ピー ホールディング （ジャージー） リミテッド 経血管的な神経変調療法のための電極および電極の位置決めシステム
EP3223712B1 (en) * 2014-11-26 2023-08-30 Sonivie Ltd. Devices for pulmonary hypertension treatment
EP3064131A1 (en) * 2015-03-03 2016-09-07 BIOTRONIK SE & Co. KG Combined vagus-phrenic nerve stimulation apparatus
SG11201706753QA (en) 2015-03-10 2017-09-28 Stent Tek Ltd Surgical system, device and methods of use thereof for the percutaneous creation of an arteriovenous fistula (avf)
AU2016248118A1 (en) * 2015-04-13 2018-02-22 Neuro Tronik IP Holding (Yersey) Limited Systems and methods for generating therapeutic electric fields for capture of nervous system targets
US20200254249A1 (en) 2015-11-17 2020-08-13 Inspire Medical Systems, Inc. Microstimulation sleep disordered breathing (sdb) therapy device
ES2977539T3 (es) * 2015-12-14 2024-08-26 Stimdia Medical Inc Estimulación eléctrica para la preservación y restablecimiento de la función del diafragma
AU2017240755B2 (en) 2016-04-01 2022-03-10 Cyberonics, Inc. Vagus nerve stimulation patient selection
WO2017184753A1 (en) 2016-04-19 2017-10-26 Inspire Medical Systems, Inc. Accelerometer-based sensing for sleep disordered breathing (sdb) care
US11478643B2 (en) 2017-01-10 2022-10-25 Inspire Medical Systems, Inc. Power element for an implantable medical device
EP3600434A4 (en) 2017-03-20 2021-01-06 Sonievie Ltd. TREATMENT OF PULMONAL HYPERTENSION
US10293164B2 (en) 2017-05-26 2019-05-21 Lungpacer Medical Inc. Apparatus and methods for assisted breathing by transvascular nerve stimulation
GB2563651A (en) * 2017-06-22 2018-12-26 Galvani Bioelectronics Ltd Nerve stimulation and monitoring device
WO2019006239A1 (en) 2017-06-30 2019-01-03 Lungpacer Medical Inc. DEVICES FOR PREVENTION, MODERATION AND / OR TREATMENT OF COGNITIVE DISORDER
US10195429B1 (en) 2017-08-02 2019-02-05 Lungpacer Medical Inc. Systems and methods for intravascular catheter positioning and/or nerve stimulation
US10940308B2 (en) 2017-08-04 2021-03-09 Lungpacer Medical Inc. Systems and methods for trans-esophageal sympathetic ganglion recruitment
WO2019046658A1 (en) * 2017-08-30 2019-03-07 The Alfred E. Mann Foundation For Scientific Research STIMULATION SYSTEMS AND METHODS FOR SELECTIVELY RECRUITING FASCICLES IN A NERVOUS TRUNK HYPOGLASS
US20190175908A1 (en) 2017-12-11 2019-06-13 Lungpacer Medical Inc. Systems and methods for strengthening a respiratory muscle
US11590341B2 (en) * 2017-12-22 2023-02-28 Electrocore, Inc Vagal nerve stimulation therapy
EP3781055B1 (en) 2018-04-20 2025-06-25 Stent Tek Limited Apparatus for orientation display and alignment in percutaneous devices
EP4548964A1 (en) 2018-11-08 2025-05-07 Lungpacer Medical Inc. Stimulation systems and related user interfaces
WO2020102193A1 (en) 2018-11-13 2020-05-22 Inspire Medical Systems, Inc. Multiple type sleep apnea
US11446485B2 (en) * 2019-04-26 2022-09-20 Nextern Innovation, Llc Lead for the temporary stimulation of a peripheral nerve
WO2020232333A1 (en) 2019-05-16 2020-11-19 Lungpacer Medical Inc. Systems and methods for sensing and stimulation
WO2020252037A1 (en) 2019-06-12 2020-12-17 Lungpacer Medical Inc. Circuitry for medical stimulation systems
US11324954B2 (en) 2019-06-28 2022-05-10 Covidien Lp Achieving smooth breathing by modified bilateral phrenic nerve pacing
GB2585882B (en) * 2019-07-19 2021-09-01 The Francis Crick Institute Ltd Electrochemical probe
US12262988B2 (en) 2019-07-25 2025-04-01 Inspire Medical Systems, Inc. Respiration detection
US11738197B2 (en) 2019-07-25 2023-08-29 Inspire Medical Systems, Inc. Systems and methods for operating an implantable medical device based upon sensed posture information
AU2021336294A1 (en) 2020-09-02 2023-03-30 The Alfred E. Mann Foundation For Scientific Research Electrode leads having multi-application nerve cuffs and associated systems and methods
ES3047777T3 (en) * 2020-12-21 2025-12-04 Inbrain Neuroelectronics Sl Flexible electrode carrier
DE102021110445A1 (de) 2021-02-17 2022-09-01 Stimit Ag Stimulationsmethoden für eine elektromagnetisch oder elektrisch kontrollierte Eigenatmung
PL4056135T3 (pl) 2021-03-09 2023-10-02 Circle Safe Stymulacja nerwu przeponowego
WO2022211946A1 (en) 2021-03-30 2022-10-06 The Alfred E. Mann Foundation For Scientific Research Electrode leads having nerve cuffs and associated systems
EP4366818A1 (en) 2021-07-09 2024-05-15 The Alfred E. Mann Foundation for Scientific Research Electrode leads having multi-application helical nerve cuffs and associated systems and methods
WO2023149911A1 (en) 2022-02-01 2023-08-10 The Alfred E. Mann Foundation For Scientific Research Electrode leads having nerve contact elements with coil contacts and associated systems and methods
JP2025528185A (ja) * 2022-08-11 2025-08-26 スティムディア メディカル，インコーポレイテッド 横隔膜刺激のための装置および方法
US20240066289A1 (en) * 2022-08-26 2024-02-29 Covidien Lp Endovascular deep brain stimulation
CN118217528A (zh) * 2022-12-19 2024-06-21 上海神奕医疗科技有限公司 植入式电极装置及电极系统

Family Cites Families (515)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1003992A (en) 1911-02-20 1911-09-26 Hans P Hansen Locomotive ash-pan.
US1040636A (en) 1911-05-22 1912-10-08 Corwin Telephone Mfg Company Telephony.
US1002254A (en) 1911-06-02 1911-09-05 Lyndall Forse Wheel for vehicles.
US1003501A (en) 1911-06-10 1911-09-19 Emil Podlesak Speed-governor.
US1041320A (en) 1911-08-08 1912-10-15 Loren W Mcintyre Tool for marking cement pavements.
US1019542A (en) 1911-10-06 1912-03-05 Albert Henry Smith Feed mechanism for automatic lathes.
US1033559A (en) 1911-11-06 1912-07-23 Joseph E Dunn Mechanism for concentrating liquids.
US1030027A (en) 1912-01-04 1912-06-18 Floyd L Stage Vehicle-signal.
US1031503A (en) 1912-01-18 1912-07-02 David Alfven Milking-machine.
US1036936A (en) 1912-01-19 1912-08-27 Acme Wire Co Electrical coil and method of making the same.
US1044899A (en) 1912-02-21 1912-11-19 George S Mclean Wire-straightener.
US1029316A (en) 1912-03-06 1912-06-11 Harris L Rosenthal Machine for piling textile fabrics.
US1049327A (en) 1912-04-29 1913-01-07 Marseilles Company Elevator-drag.
US1039131A (en) 1912-06-18 1912-09-24 Matthews & Co Jas H Changeable type-blocks.
US1693734A (en) 1923-06-29 1928-12-04 Mcintosh Electrical Corp Switching means for effecting electrotherapeutic treatment
US2532788A (en) 1948-01-03 1950-12-05 Stanley J Sarnoff Artificial respiration by electronic stimulation
US2664880A (en) 1951-11-23 1954-01-05 Jr Nathaniel B Wales Electric stimulator for artificial respiration
US3348548A (en) 1965-04-26 1967-10-24 William M Chardack Implantable electrode with stiffening stylet
US3470876A (en) 1966-09-28 1969-10-07 John Barchilon Dirigible catheter
US3835864A (en) 1970-09-21 1974-09-17 Rasor Ass Inc Intra-cardiac stimulator
US3769984A (en) 1971-03-11 1973-11-06 Sherwood Medical Ind Inc Pacing catheter with frictional fit lead attachment
US3817241A (en) 1972-02-16 1974-06-18 Henry And Carol Grausz Disposable central venous catheter and method of use
US3938502A (en) 1972-02-22 1976-02-17 Nicolaas Bom Apparatus with a catheter for examining hollow organs or bodies with the ultrasonic waves
US3804098A (en) 1972-04-17 1974-04-16 Medronic Inc Body implantable lead
US3896373A (en) 1972-11-30 1975-07-22 Stein Paul D Method and apparatus for determining cross-sectional area of a blood conduit and volumetric flow therethrough
US3847157A (en) 1973-06-18 1974-11-12 J Caillouette Medico-surgical tube
US3851641A (en) 1973-11-29 1974-12-03 J Toole Method and apparatus for determining internal impedance of animal body part
US3983881A (en) 1975-05-21 1976-10-05 Telectronics Pty. Limited Muscle stimulator
US4054881A (en) 1976-04-26 1977-10-18 The Austin Company Remote object position locater
US4114601A (en) 1976-08-09 1978-09-19 Micro Tec Instrumentation, Inc. Medical and surgical implement detection system
US4072146A (en) 1976-09-08 1978-02-07 Howes Randolph M Venous catheter device
USRE31873F1 (en) 1976-09-08 1988-11-15 Venous catheter device
US4143872A (en) 1977-04-07 1979-03-13 Hudson Oxygen Therapy Sales Company Lung volume exerciser
US4173228A (en) 1977-05-16 1979-11-06 Applied Medical Devices Catheter locating device
US4249539A (en) 1979-02-09 1981-02-10 Technicare Corporation Ultrasound needle tip localization system
US4317078A (en) 1979-10-15 1982-02-23 Ohio State University Research Foundation Remote position and orientation detection employing magnetic flux linkage
US4380237A (en) 1979-12-03 1983-04-19 Massachusetts General Hospital Apparatus for making cardiac output conductivity measurements
US4643201A (en) 1981-02-02 1987-02-17 Medtronic, Inc. Single-pass A-V lead
US4431005A (en) 1981-05-07 1984-02-14 Mccormick Laboratories, Inc. Method of and apparatus for determining very accurately the position of a device inside biological tissue
US4416289A (en) 1981-05-07 1983-11-22 Mccormick Laboratories, Inc. Circuits for determining very accurately the position of a device inside biological tissue
US4445501A (en) 1981-05-07 1984-05-01 Mccormick Laboratories, Inc. Circuits for determining very accurately the position of a device inside biological tissue
US4431006A (en) 1982-01-07 1984-02-14 Technicare Corporation Passive ultrasound needle probe locator
US4407294A (en) 1982-01-07 1983-10-04 Technicare Corporation Ultrasound tissue probe localization system
US4681117A (en) 1983-02-15 1987-07-21 Brodman Richard F Intracardiac catheter and a method for detecting myocardial ischemia
US4573481A (en) 1984-06-25 1986-03-04 Huntington Institute Of Applied Research Implantable electrode array
US4586923A (en) 1984-06-25 1986-05-06 Cordis Corporation Curving tip catheter
US4587975A (en) 1984-07-02 1986-05-13 Cardiac Pacemakers, Inc. Dimension sensitive angioplasty catheter
US4697595A (en) 1984-07-24 1987-10-06 Telectronics N.V. Ultrasonically marked cardiac catheters
YU132884A (en) 1984-07-26 1987-12-31 Branko Breyer Electrode cateter with ultrasonic marking
US4674518A (en) 1985-09-06 1987-06-23 Cardiac Pacemakers, Inc. Method and apparatus for measuring ventricular volume
US4683890A (en) 1985-12-23 1987-08-04 Brunswick Manufacturing Co., Inc. Method and apparatus for controlled breathing employing internal and external electrodes
US4827935A (en) 1986-04-24 1989-05-09 Purdue Research Foundation Demand electroventilator
US4771788A (en) 1986-07-18 1988-09-20 Pfizer Hospital Products Group, Inc. Doppler tip wire guide
US4852580A (en) 1986-09-17 1989-08-01 Axiom Medical, Inc. Catheter for measuring bioimpedance
US4830008A (en) 1987-04-24 1989-05-16 Meer Jeffrey A Method and system for treatment of sleep apnea
US4819662A (en) 1987-10-26 1989-04-11 Cardiac Pacemakers, Inc. Cardiac electrode with drug delivery capabilities
US4860769A (en) 1987-11-12 1989-08-29 Thomas J. Fogarty Implantable defibrillation electrode
CA1330285C (en) 1987-12-22 1994-06-21 Geoffrey S. Martin Triple lumen catheter
US4840182A (en) 1988-04-04 1989-06-20 Rhode Island Hospital Conductance catheter
US4944088A (en) 1988-05-25 1990-07-31 Medtronic, Inc. Ring electrode for multiconductor pacing leads
US4951682A (en) 1988-06-22 1990-08-28 The Cleveland Clinic Foundation Continuous cardiac output by impedance measurements in the heart
US4905698A (en) 1988-09-13 1990-03-06 Pharmacia Deltec Inc. Method and apparatus for catheter location determination
US4911174A (en) 1989-02-13 1990-03-27 Cardiac Pacemakers, Inc. Method for matching the sense length of an impedance measuring catheter to a ventricular chamber
US4957110A (en) 1989-03-17 1990-09-18 C. R. Bard, Inc. Steerable guidewire having electrodes for measuring vessel cross-section and blood flow
US4934049A (en) 1989-07-07 1990-06-19 Medtronic, Inc. Method for fabrication of a medical electrode
US4989617A (en) 1989-07-14 1991-02-05 Case Western Reserve University Intramuscular electrode for neuromuscular stimulation system
US5010895A (en) * 1989-08-03 1991-04-30 Empi, Inc. Expandable vaginal electrode
US5036848A (en) 1989-10-16 1991-08-06 Brunswick Biomedical Technologies, Inc. Method and apparatus for controlling breathing employing internal and external electrodes
US5005587A (en) 1989-11-13 1991-04-09 Pacing Systems, Inc. Braid Electrode leads and catheters and methods for using the same
US5254088A (en) 1990-02-02 1993-10-19 Ep Technologies, Inc. Catheter steering mechanism
US5115818A (en) 1990-02-14 1992-05-26 Medtronic, Inc. Implantable electrode
US5042143A (en) 1990-02-14 1991-08-27 Medtronic, Inc. Method for fabrication of implantable electrode
CH681351A5 (enExample) 1990-04-12 1993-03-15 Hans Baer Dr
US5056519A (en) 1990-05-14 1991-10-15 Vince Dennis J Unilateral diaphragmatic pacer
US5265604A (en) 1990-05-14 1993-11-30 Vince Dennis J Demand - diaphragmatic pacing (skeletal muscle pressure modified)
US5383923A (en) 1990-10-20 1995-01-24 Webster Laboratories, Inc. Steerable catheter having puller wire with shape memory
DE9015857U1 (de) 1990-11-21 1991-02-07 B. Braun Melsungen Ag, 3508 Melsungen Führungssonde
US5170802A (en) 1991-01-07 1992-12-15 Medtronic, Inc. Implantable electrode for location within a blood vessel
US5224491A (en) 1991-01-07 1993-07-06 Medtronic, Inc. Implantable electrode for location within a blood vessel
US5465717A (en) 1991-02-15 1995-11-14 Cardiac Pathways Corporation Apparatus and Method for ventricular mapping and ablation
US5345936A (en) 1991-02-15 1994-09-13 Cardiac Pathways Corporation Apparatus with basket assembly for endocardial mapping
US5456254A (en) 1991-02-15 1995-10-10 Cardiac Pathways Corp Flexible strip assembly having insulating layer with conductive pads exposed through insulating layer and device utilizing the same
US5156151A (en) * 1991-02-15 1992-10-20 Cardiac Pathways Corporation Endocardial mapping and ablation system and catheter probe
US5146918A (en) 1991-03-19 1992-09-15 Medtronic, Inc. Demand apnea control of central and obstructive sleep apnea
US5184621A (en) 1991-05-29 1993-02-09 C. R. Bard, Inc. Steerable guidewire having electrodes for measuring vessel cross-section and blood flow
JP2582010B2 (ja) 1991-07-05 1997-02-19 芳嗣 山田 呼吸筋活動のモニタ装置
US5241957A (en) 1991-11-18 1993-09-07 Medtronic, Inc. Bipolar temporary pacing lead and connector and permanent bipolar nerve wire
US5509411A (en) 1993-01-29 1996-04-23 Cardima, Inc. Intravascular sensing device
US5324322A (en) 1992-04-20 1994-06-28 Case Western Reserve University Thin film implantable electrode and method of manufacture
US5843028A (en) 1992-05-11 1998-12-01 Medical Innovations Corporation Multi-lumen endoscopic catheter
US5411025A (en) 1992-06-30 1995-05-02 Cordis Webster, Inc. Cardiovascular catheter with laterally stable basket-shaped electrode array
WO1994007564A2 (en) 1992-10-01 1994-04-14 Cardiac Pacemakers, Inc. Stent-type defibrillation electrode structures
EP1046406B1 (en) 1992-12-04 2003-10-15 C.R. Bard, Inc. Actuator for use with a catheter with independent proximal and distal control
US5368564A (en) 1992-12-23 1994-11-29 Angeion Corporation Steerable catheter
US5330522A (en) 1992-12-29 1994-07-19 Siemens Pacesetter, Inc. Ring electrode for a multilumen lead and method of constructing a multilumen lead
US5813399A (en) 1993-03-16 1998-09-29 Puritan Bennett Corporation System and method for closed loop airway pressure control during the inspiratory cycle of a breath in a patient ventilator using the exhalation valve as a microcomputer-controlled relief valve
JPH08511005A (ja) 1993-06-01 1996-11-19 コーテックス ファーマシューティカルズ インコーポレイテッド 神経疾患の治療におけるアルカリ性または酸性ホスファターゼインヒビター
US5348536A (en) 1993-08-02 1994-09-20 Quinton Instrument Company Coextruded catheter and method of forming
US5607462A (en) 1993-09-24 1997-03-04 Cardiac Pathways Corporation Catheter assembly, catheter and multi-catheter introducer for use therewith
US5486159A (en) 1993-10-01 1996-01-23 Mahurkar; Sakharam D. Multiple-lumen catheter
US5555618A (en) 1993-10-12 1996-09-17 Arrow International Investment Corp. Method of making electrode-carrying catheter
US5417208A (en) 1993-10-12 1995-05-23 Arrow International Investment Corp. Electrode-carrying catheter and method of making same
US5524632A (en) 1994-01-07 1996-06-11 Medtronic, Inc. Method for implanting electromyographic sensing electrodes
US5527358A (en) 1994-01-21 1996-06-18 Medtronic, Inc. Temporary medical electrical lead
JP3269125B2 (ja) 1994-01-28 2002-03-25 東レ株式会社 アトピー性皮膚炎治療薬
US5476498A (en) 1994-08-15 1995-12-19 Incontrol, Inc. Coronary sinus channel lead and method
US5549655A (en) 1994-09-21 1996-08-27 Medtronic, Inc. Method and apparatus for synchronized treatment of obstructive sleep apnea
US5604231A (en) 1995-01-06 1997-02-18 Smith; Carr J. Pharmaceutical compositions for prevention and treatment of ulcerative colitis
US5678535A (en) 1995-04-21 1997-10-21 Dimarco; Anthony Fortunato Method and apparatus for electrical stimulation of the respiratory muscles to achieve artificial ventilation in a patient
US5584873A (en) 1995-05-08 1996-12-17 Medtronic, Inc. Medical lead with compression lumens
AU7286996A (en) 1995-10-18 1997-05-07 Ciba-Geigy Ag Thermopile powered transdermal drug delivery device
US6198970B1 (en) 1995-10-27 2001-03-06 Esd Limited Liability Company Method and apparatus for treating oropharyngeal respiratory and oral motor neuromuscular disorders with electrical stimulation
EP0955881B1 (en) 1995-11-17 2001-05-23 New York University Apparatus and method for pressure and temperature waveform analysis
US5697377A (en) 1995-11-22 1997-12-16 Medtronic, Inc. Catheter mapping system and method
NL1001890C2 (nl) * 1995-12-13 1997-06-17 Cordis Europ Catheter met plaatvormige elektrode-reeks.
US5716392A (en) 1996-01-05 1998-02-10 Medtronic, Inc. Minimally invasive medical electrical lead
US6096728A (en) 1996-02-09 2000-08-01 Amgen Inc. Composition and method for treating inflammatory diseases
US5772693A (en) 1996-02-09 1998-06-30 Cardiac Control Systems, Inc. Single preformed catheter configuration for a dual-chamber pacemaker system
US5665103A (en) 1996-03-07 1997-09-09 Scimed Life Systems, Inc. Stent locating device
US6166048A (en) 1999-04-20 2000-12-26 Targacept, Inc. Pharmaceutical compositions for inhibition of cytokine production and secretion
US7225019B2 (en) 1996-04-30 2007-05-29 Medtronic, Inc. Method and system for nerve stimulation and cardiac sensing prior to and during a medical procedure
US20070208388A1 (en) 1996-04-30 2007-09-06 Jahns Scott E Method and system for nerve stimulation and cardiac sensing prior to and during a medical procedure
USRE38705E1 (en) 1996-04-30 2005-02-22 Medtronic, Inc. Method and device for electronically controlling the beating of a heart using venous electrical stimulation of nerve fibers
US6449507B1 (en) 1996-04-30 2002-09-10 Medtronic, Inc. Method and system for nerve stimulation prior to and during a medical procedure
US6006134A (en) 1998-04-30 1999-12-21 Medtronic, Inc. Method and device for electronically controlling the beating of a heart using venous electrical stimulation of nerve fibers
US5913848A (en) 1996-06-06 1999-06-22 Luther Medical Products, Inc. Hard tip over-the-needle catheter and method of manufacturing the same
US5827192A (en) 1996-08-21 1998-10-27 Cleveland Clinic Foundation Method of determining the conductivity of blood
US5971933A (en) 1996-09-17 1999-10-26 Cleveland Clinic Foundation Method and apparatus to correct for electric field non-uniformity in conductance catheter volumetry
SE9603841D0 (sv) 1996-10-18 1996-10-18 Pacesetter Ab A tissue stimulating apparatus
US5776111A (en) 1996-11-07 1998-07-07 Medical Components, Inc. Multiple catheter assembly
US5785706A (en) * 1996-11-18 1998-07-28 Daig Corporation Nonsurgical mapping and treatment of cardiac arrhythmia using a catheter contained within a guiding introducer containing openings
US5782828A (en) 1996-12-11 1998-07-21 Irvine Biomedical, Inc. Ablation catheter with multiple flexible curves
US5755765A (en) 1997-01-24 1998-05-26 Cardiac Pacemakers, Inc. Pacing lead having detachable positioning member
US5916163A (en) 1997-03-07 1999-06-29 Ep Technologies, Inc. Graphical user interface for use with multiple electrode catheters
US5954761A (en) * 1997-03-25 1999-09-21 Intermedics Inc. Implantable endocardial lead assembly having a stent
US5779732A (en) 1997-03-31 1998-07-14 Medtronic, Inc. Method and apparatus for implanting a film with an exandable stent
US5944022A (en) 1997-04-28 1999-08-31 American Cardiac Ablation Co. Inc. Catheter positioning system
US6869431B2 (en) 1997-07-08 2005-03-22 Atrionix, Inc. Medical device with sensor cooperating with expandable member
US5824027A (en) 1997-08-14 1998-10-20 Simon Fraser University Nerve cuff having one or more isolated chambers
US6479523B1 (en) 1997-08-26 2002-11-12 Emory University Pharmacologic drug combination in vagal-induced asystole
US6249708B1 (en) 1997-08-26 2001-06-19 Angeion Corporation Fluted channel construction for a multi-conductor catheter lead
US5922014A (en) 1997-09-02 1999-07-13 Medtronic, Inc. Single pass lead and method of use
US6024702A (en) 1997-09-03 2000-02-15 Pmt Corporation Implantable electrode manufactured with flexible printed circuit
US6123699A (en) 1997-09-05 2000-09-26 Cordis Webster, Inc. Omni-directional steerable catheter
US6179832B1 (en) * 1997-09-11 2001-01-30 Vnus Medical Technologies, Inc. Expandable catheter having two sets of electrodes
US6183463B1 (en) 1997-12-01 2001-02-06 Cordis Webster, Inc. Bidirectional steerable cathether with bidirectional control handle
US6120476A (en) 1997-12-01 2000-09-19 Cordis Webster, Inc. Irrigated tip catheter
US6171277B1 (en) 1997-12-01 2001-01-09 Cordis Webster, Inc. Bi-directional control handle for steerable catheter
US6415187B1 (en) 1998-02-10 2002-07-02 Advanced Bionics Corporation Implantable, expandable, multicontact electrodes and insertion needle for use therewith
US6251126B1 (en) 1998-04-23 2001-06-26 Medtronic Inc Method and apparatus for synchronized treatment of obstructive sleep apnea
US6269269B1 (en) 1998-04-23 2001-07-31 Medtronic Inc. Method and apparatus for synchronized treatment of obstructive sleep apnea
US6161047A (en) 1998-04-30 2000-12-12 Medtronic Inc. Apparatus and method for expanding a stimulation lead body in situ
DE29902386U1 (de) 1998-05-12 1999-06-17 PROSAN d.o.o., Ruše Spülkasten für ein WC-Klosett
US6240320B1 (en) 1998-06-05 2001-05-29 Intermedics Inc. Cardiac lead with zone insulated electrodes
US6134478A (en) 1998-06-05 2000-10-17 Intermedics Inc. Method for making cardiac leads with zone insulated electrodes
US6002965A (en) 1998-06-10 1999-12-14 Katz; Amiram Self applied device and method for prevention of deep vein thrombosis
US6463327B1 (en) 1998-06-11 2002-10-08 Cprx Llc Stimulatory device and methods to electrically stimulate the phrenic nerve
US6213960B1 (en) 1998-06-19 2001-04-10 Revivant Corporation Chest compression device with electro-stimulation
WO1999065561A1 (en) 1998-06-19 1999-12-23 Cordis Webster, Inc. Method and apparatus for transvascular treatment of tachycardia and fibrillation
SE9802335D0 (sv) 1998-06-30 1998-06-30 Siemens Elema Ab Andningshjälpsystem
US6322559B1 (en) * 1998-07-06 2001-11-27 Vnus Medical Technologies, Inc. Electrode catheter having coil structure
US6198974B1 (en) 1998-08-14 2001-03-06 Cordis Webster, Inc. Bi-directional steerable catheter
US7972323B1 (en) 1998-10-02 2011-07-05 Boston Scientific Scimed, Inc. Steerable device for introducing diagnostic and therapeutic apparatus into the body
FR2784300B1 (fr) 1998-10-13 2000-12-08 Ela Medical Sa Sonde de stimulation du ventricule gauche implantable dans le reseau veineux coronarien pour dispositif medical implantable actif, notamment stimulateur de type "multisite"
SE9803508D0 (sv) 1998-10-14 1998-10-14 Siemens Elema Ab System for assisted breathing
US6208881B1 (en) 1998-10-20 2001-03-27 Micropure Medical, Inc. Catheter with thin film electrodes and method for making same
US7076307B2 (en) 2002-05-09 2006-07-11 Boveja Birinder R Method and system for modulating the vagus nerve (10th cranial nerve) with electrical pulses using implanted and external components, to provide therapy neurological and neuropsychiatric disorders
US6212435B1 (en) 1998-11-13 2001-04-03 Respironics, Inc. Intraoral electromuscular stimulation device and method
EP1025822A1 (de) 1999-02-08 2000-08-09 Paul Hartmann Aktiengesellschaft Saugkörper für Hygieneartikel
US6210339B1 (en) 1999-03-03 2001-04-03 Endosonics Corporation Flexible elongate member having one or more electrical contacts
US6161029A (en) 1999-03-08 2000-12-12 Medtronic, Inc. Apparatus and method for fixing electrodes in a blood vessel
DE19912635A1 (de) 1999-03-20 2000-09-21 Biotronik Mess & Therapieg Dilatierbare Herzelektrodenanordnung zur Implantation insbesondere im Koronarsinus des Herzens
US6136021A (en) 1999-03-23 2000-10-24 Cardiac Pacemakers, Inc. Expandable electrode for coronary venous leads
US6593754B1 (en) 1999-04-01 2003-07-15 Actuant Corporation Compact subsurface object locator
US6216045B1 (en) 1999-04-26 2001-04-10 Advanced Neuromodulation Systems, Inc. Implantable lead and method of manufacture
US6126649A (en) 1999-06-10 2000-10-03 Transvascular, Inc. Steerable catheter with external guidewire as catheter tip deflector
CA2376903A1 (en) 1999-06-25 2001-01-04 Emory University Devices and methods for vagus nerve stimulation
WO2001000264A1 (en) 1999-06-30 2001-01-04 University Of Florida Research Foundation, Inc. Ventilator monitor system and method of using same
US6702780B1 (en) 1999-09-08 2004-03-09 Super Dimension Ltd. Steering configuration for catheter with rigid distal device
US6236892B1 (en) 1999-10-07 2001-05-22 Claudio A. Feler Spinal cord stimulation lead
US6295475B1 (en) 1999-10-27 2001-09-25 Pacesetter, Inc. Single-pass atrial ventricular lead with multiple atrial ring electrodes and a selective atrial electrode adaptor for the coronary sinus region
US7177686B1 (en) 1999-11-10 2007-02-13 Pacesetter, Inc. Using photo-plethysmography to monitor autonomic tone and performing pacing optimization based on monitored autonomic tone
US20040215235A1 (en) * 1999-11-16 2004-10-28 Barrx, Inc. Methods and systems for determining physiologic characteristics for treatment of the esophagus
US6556873B1 (en) 1999-11-29 2003-04-29 Medtronic, Inc. Medical electrical lead having variable bending stiffness
US20020026228A1 (en) 1999-11-30 2002-02-28 Patrick Schauerte Electrode for intravascular stimulation, cardioversion and/or defibrillation
US6415183B1 (en) 1999-12-09 2002-07-02 Cardiac Pacemakers, Inc. Method and apparatus for diaphragmatic pacing
US8221402B2 (en) * 2000-01-19 2012-07-17 Medtronic, Inc. Method for guiding a medical device
US6885888B2 (en) 2000-01-20 2005-04-26 The Cleveland Clinic Foundation Electrical stimulation of the sympathetic nerve chain
US6493590B1 (en) 2000-02-09 2002-12-10 Micronet Medical, Inc. Flexible band electrodes for medical leads
AU2001257582A1 (en) 2000-03-14 2001-09-24 Children's Medical Center Corporation, The Method for improving respiratory function and inhibiting muscular degeneration
US6397108B1 (en) 2000-04-03 2002-05-28 Medtronic Inc. Safety adaptor for temporary medical leads
US6638268B2 (en) * 2000-04-07 2003-10-28 Imran K. Niazi Catheter to cannulate the coronary sinus
US6442413B1 (en) * 2000-05-15 2002-08-27 James H. Silver Implantable sensor
US6610713B2 (en) 2000-05-23 2003-08-26 North Shore - Long Island Jewish Research Institute Inhibition of inflammatory cytokine production by cholinergic agonists and vagus nerve stimulation
US6508802B1 (en) 2000-05-23 2003-01-21 Cornell Research Foundation, Inc. Remote sensing gene therapy delivery device and method of administering a therapeutic solution to a heart
US6719749B1 (en) 2000-06-01 2004-04-13 Medical Components, Inc. Multilumen catheter assembly and methods for making and inserting the same
US6695832B2 (en) 2000-06-01 2004-02-24 Twincath, Llc Multilumen catheter and methods for making the catheter
US20030125786A1 (en) * 2000-07-13 2003-07-03 Gliner Bradford Evan Methods and apparatus for effectuating a lasting change in a neural-function of a patient
US6584362B1 (en) 2000-08-30 2003-06-24 Cardiac Pacemakers, Inc. Leads for pacing and/or sensing the heart from within the coronary veins
US7149585B2 (en) 2001-03-30 2006-12-12 Micronet Medical, Inc. Lead body and method of lead body construction
US7555349B2 (en) 2000-09-26 2009-06-30 Advanced Neuromodulation Systems, Inc. Lead body and method of lead body construction
US7499742B2 (en) * 2001-09-26 2009-03-03 Cvrx, Inc. Electrode structures and methods for their use in cardiovascular reflex control
US6757970B1 (en) 2000-11-07 2004-07-06 Advanced Bionics Corporation Method of making multi-contact electrode array
SE0004141D0 (sv) 2000-11-13 2000-11-13 Siemens Elema Ab Method for adaptive triggering of breathing devices and a breathing device
WO2002045795A2 (en) * 2000-12-07 2002-06-13 Medtronic, Inc. Directional brain stimulation and recording leads
US7519421B2 (en) 2001-01-16 2009-04-14 Kenergy, Inc. Vagal nerve stimulation using vascular implanted devices for treatment of atrial fibrillation
US6445953B1 (en) 2001-01-16 2002-09-03 Kenergy, Inc. Wireless cardiac pacing system with vascular electrode-stents
DE10103288A1 (de) 2001-01-25 2002-08-01 Patrick Schauerte Gefäßschleuse zur intravaskulären Nervenstimulation und Flüssigkeitsinfusion
DE10105383C2 (de) 2001-02-06 2003-06-05 Heptec Gmbh Antischnarchgerät
ZA200306564B (en) 2001-02-26 2004-10-15 Optinose As Nasal devices.
US7167751B1 (en) 2001-03-01 2007-01-23 Advanced Bionics Corporation Method of using a fully implantable miniature neurostimulator for vagus nerve stimulation
US6585718B2 (en) 2001-05-02 2003-07-01 Cardiac Pacemakers, Inc. Steerable catheter with shaft support system for resisting axial compressive loads
CA2448912C (en) 2001-05-30 2012-01-03 Innersa Technology Implantable devices having a liquid crystal polymer substrate
JP4295086B2 (ja) 2001-07-11 2009-07-15 ヌバシブ， インコーポレイテッド 手術の間の神経近接度、神経の方向、および病理学を決定するシステムおよび方法
US6569114B2 (en) 2001-08-31 2003-05-27 Biosense Webster, Inc. Steerable catheter with struts
US7974693B2 (en) 2001-08-31 2011-07-05 Bio Control Medical (B.C.M.) Ltd. Techniques for applying, configuring, and coordinating nerve fiber stimulation
EP1435828A4 (en) 2001-09-25 2009-11-11 Nuvasive Inc SYSTEM AND METHOD FOR IMPLEMENTING SURGICAL INTERVENTIONS AND INVESTIGATIONS
US7168429B2 (en) 2001-10-12 2007-01-30 Ric Investments, Llc Auto-titration pressure support system and method of using same
US6934583B2 (en) 2001-10-22 2005-08-23 Pacesetter, Inc. Implantable lead and method for stimulating the vagus nerve
US6993384B2 (en) * 2001-12-04 2006-01-31 Advanced Bionics Corporation Apparatus and method for determining the relative position and orientation of neurostimulation leads
US6721603B2 (en) 2002-01-25 2004-04-13 Cyberonics, Inc. Nerve stimulation as a treatment for pain
WO2003068944A2 (en) 2002-02-13 2003-08-21 Dana-Farber Cancer Institute, Inc. METHODS AND COMPOSITION FOR MODULATING TYPE I MUSCLE FORMATION USING PGC-1α-
US7620451B2 (en) * 2005-12-29 2009-11-17 Ardian, Inc. Methods and apparatus for pulsed electric field neuromodulation via an intra-to-extravascular approach
US7653438B2 (en) 2002-04-08 2010-01-26 Ardian, Inc. Methods and apparatus for renal neuromodulation
US20030195571A1 (en) 2002-04-12 2003-10-16 Burnes John E. Method and apparatus for the treatment of central sleep apnea using biventricular pacing
US6978178B2 (en) * 2002-04-30 2005-12-20 Medtronic, Inc. Method and apparatus for selecting an optimal electrode configuration of a medical electrical lead having a multiple electrode array
BR0311849A (pt) 2002-05-08 2005-04-05 Univ California Sistema para formar um bloqueio de condução em uma estrutura de tecido cardìaco para tratar uma arritmia cardìaca em um coração de um paciente, métodos para tratar uma arritmia cardìaca em um coração de um paciente e para montar um sistema de tratamento de arritmia cardìaca a partir de uma pluralidade de sistemas de distribuição cardìacos, e, sistema para tratar uma arritmia cardìaca em um coração de um paciente
US7292890B2 (en) 2002-06-20 2007-11-06 Advanced Bionics Corporation Vagus nerve stimulation via unidirectional propagation of action potentials
SE0202537D0 (sv) 2002-08-28 2002-08-28 Siemens Elema Ab Nervstimuleringsapparat
US20040064069A1 (en) 2002-09-30 2004-04-01 Reynolds Brian R. Medical device with support member
SE0203108D0 (en) 2002-10-22 2002-10-22 Siemens Elema Ab Multi-Electrode Catheter
US20050033137A1 (en) 2002-10-25 2005-02-10 The Regents Of The University Of Michigan Ablation catheters and methods for their use
US7277757B2 (en) 2002-10-31 2007-10-02 Medtronic, Inc. Respiratory nerve stimulation
US7130700B2 (en) 2002-11-19 2006-10-31 Medtronic, Inc. Multilumen body for an implantable medical device
US20040111139A1 (en) 2002-12-10 2004-06-10 Mccreery Douglas B. Apparatus and methods for differential stimulation of nerve fibers
US7613515B2 (en) 2003-02-03 2009-11-03 Enteromedics Inc. High frequency vagal blockage therapy
CA2516559C (en) 2003-02-21 2016-09-27 Electro-Cat, Llc System and method for measuring cross-sectional areas and pressure gradients in luminal organs
US7142903B2 (en) 2003-03-12 2006-11-28 Biosense Webster, Inc. Catheter with contractable mapping assembly
US7155278B2 (en) 2003-04-21 2006-12-26 Medtronic, Inc. Neurostimulation to treat effects of sleep apnea
EP3064242A1 (en) 2003-04-28 2016-09-07 Advanced Circulatory Systems Inc. Ventilator and methods for treating head trauma and low blood circulation
US20060287679A1 (en) 2003-05-16 2006-12-21 Stone Robert T Method and system to control respiration by means of confounding neuro-electrical signals
US20060111755A1 (en) 2003-05-16 2006-05-25 Stone Robert T Method and system to control respiration by means of neuro-electrical coded signals
US6999820B2 (en) 2003-05-29 2006-02-14 Advanced Neuromodulation Systems, Inc. Winged electrode body for spinal cord stimulation
US7529589B2 (en) * 2003-06-04 2009-05-05 Synecor Llc Intravascular electrophysiological system and methods
US7235070B2 (en) 2003-07-02 2007-06-26 St. Jude Medical, Atrial Fibrillation Division, Inc. Ablation fluid manifold for ablation catheter
TW200503738A (en) 2003-07-16 2005-02-01 Tzu Chi Buddhist General Hospital Method for extracting antineoplastic components from bupleurum scorzonerifolium
US7840270B2 (en) 2003-07-23 2010-11-23 Synapse Biomedical, Inc. System and method for conditioning a diaphragm of a patient
US20050027338A1 (en) 2003-07-29 2005-02-03 Advanced Neuromodulation Systems, Inc. Stretchable lead body, method of manufacture, and system
US20050033136A1 (en) 2003-08-01 2005-02-10 Assaf Govari Catheter with electrode strip
US7591265B2 (en) 2003-09-18 2009-09-22 Cardiac Pacemakers, Inc. Coordinated use of respiratory and cardiac therapies for sleep disordered breathing
US7662101B2 (en) 2003-09-18 2010-02-16 Cardiac Pacemakers, Inc. Therapy control based on cardiopulmonary status
EP1660004A4 (en) 2003-08-18 2017-05-31 Breathe Technologies, Inc. Method and device for non-invasive ventilation with nasal interface
ATE413902T1 (de) 2003-08-18 2008-11-15 Cardiac Pacemakers Inc Patientenüberwachungssystem
US7887493B2 (en) 2003-09-18 2011-02-15 Cardiac Pacemakers, Inc. Implantable device employing movement sensing for detecting sleep-related disorders
US8147486B2 (en) 2003-09-22 2012-04-03 St. Jude Medical, Atrial Fibrillation Division, Inc. Medical device with flexible printed circuit
US7502650B2 (en) * 2003-09-22 2009-03-10 Cvrx, Inc. Baroreceptor activation for epilepsy control
US20050070981A1 (en) * 2003-09-29 2005-03-31 Sumit Verma Active fixation coronary sinus lead apparatus
NO319063B1 (no) 2003-10-06 2005-06-13 Laerdal Medical As Medisinsk pasientsimulator
US8467876B2 (en) 2003-10-15 2013-06-18 Rmx, Llc Breathing disorder detection and therapy delivery device and method
US7970475B2 (en) 2003-10-15 2011-06-28 Rmx, Llc Device and method for biasing lung volume
US20080161878A1 (en) 2003-10-15 2008-07-03 Tehrani Amir J Device and method to for independently stimulating hemidiaphragms
US20080215106A1 (en) 2003-10-15 2008-09-04 Chang Lee Thoracoscopically implantable diaphragm stimulator
US20080288015A1 (en) 2003-10-15 2008-11-20 Rmx, Llc Diaphragm stimulation device and method for use with cardiovascular or heart patients
US8265759B2 (en) 2003-10-15 2012-09-11 Rmx, Llc Device and method for treating disorders of the cardiovascular system or heart
US9259573B2 (en) 2003-10-15 2016-02-16 Rmx, Llc Device and method for manipulating exhalation
US20110288609A1 (en) 2003-10-15 2011-11-24 Rmx, Llc Therapeutic diaphragm stimulation device and method
US8244358B2 (en) 2003-10-15 2012-08-14 Rmx, Llc Device and method for treating obstructive sleep apnea
US20080288010A1 (en) 2003-10-15 2008-11-20 Rmx, Llc Subcutaneous diaphragm stimulation device and method for use
US20060167523A1 (en) 2003-10-15 2006-07-27 Tehrani Amir J Device and method for improving upper airway functionality
US7979128B2 (en) 2003-10-15 2011-07-12 Rmx, Llc Device and method for gradually controlling breathing
US8160711B2 (en) 2003-10-15 2012-04-17 Rmx, Llc Multimode device and method for controlling breathing
US20120158091A1 (en) 2003-10-15 2012-06-21 Rmx, Llc Therapeutic diaphragm stimulation device and method
US8140164B2 (en) 2003-10-15 2012-03-20 Rmx, Llc Therapeutic diaphragm stimulation device and method
US7142919B2 (en) * 2003-10-24 2006-11-28 Medtronic, Inc. Reconfigurable, fault tolerant multiple-electrode cardiac lead systems
US20060074449A1 (en) * 2003-11-03 2006-04-06 Stephen Denker Intravascular stimulation system with wireless power supply
US7077823B2 (en) 2003-11-19 2006-07-18 Biosense Webster, Inc. Bidirectional steerable catheter with slidable mated puller wires
US7802571B2 (en) 2003-11-21 2010-09-28 Tehrani Fleur T Method and apparatus for controlling a ventilator
WO2005053789A2 (en) 2003-11-25 2005-06-16 Advanced Neuromodulation Systems, Inc. Directional stimulation lead and orientation system, and improved percutaneous-insertion needle and method of implanting a lead
US7363085B1 (en) 2004-01-26 2008-04-22 Pacesetters, Inc. Augmenting hypoventilation
US7421296B1 (en) 2004-01-26 2008-09-02 Pacesetter, Inc. Termination of respiratory oscillations characteristic of Cheyne-Stokes respiration
US7519425B2 (en) 2004-01-26 2009-04-14 Pacesetter, Inc. Tiered therapy for respiratory oscillations characteristic of Cheyne-Stokes respiration
CN100544670C (zh) 2004-02-18 2009-09-30 马奎特紧急护理公司 使用肌电活动来优化病人的呼吸辅助的设备
US7569029B2 (en) 2004-04-12 2009-08-04 Clark Timothy W I Multi-lumen catheter
US7082331B1 (en) 2004-04-21 2006-07-25 Pacesetter, Inc. System and method for applying therapy during hyperpnea phase of periodic breathing using an implantable medical device
US7245971B2 (en) * 2004-04-21 2007-07-17 Pacesetter, Inc. System and method for applying therapy during hyperpnea phase of periodic breathing using an implantable medical device
US8412348B2 (en) * 2004-05-06 2013-04-02 Boston Scientific Neuromodulation Corporation Intravascular self-anchoring integrated tubular electrode body
US20070106357A1 (en) 2005-11-04 2007-05-10 Stephen Denker Intravascular Electronics Carrier Electrode for a Transvascular Tissue Stimulation System
US7747323B2 (en) 2004-06-08 2010-06-29 Cardiac Pacemakers, Inc. Adaptive baroreflex stimulation therapy for disordered breathing
US7591799B2 (en) 2004-06-14 2009-09-22 Biosense Webster, Inc. Steering mechanism for bi-directional catheter
US7225016B1 (en) 2004-06-16 2007-05-29 Pacesetter, Inc. Implantable medical device with nerve signal sensing
US7371220B1 (en) 2004-06-30 2008-05-13 Pacesetter, Inc. System and method for real-time apnea/hypopnea detection using an implantable medical system
US7962215B2 (en) 2004-07-23 2011-06-14 Synapse Biomedical, Inc. Ventilatory assist system and methods to improve respiratory function
EP1621247A1 (de) 2004-07-30 2006-02-01 MAN DWE GmbH Durchführung von exothermen Gasphasenreaktionen
US20060058852A1 (en) 2004-09-10 2006-03-16 Steve Koh Multi-variable feedback control of stimulation for inspiratory facilitation
US7340302B1 (en) 2004-09-27 2008-03-04 Pacesetter, Inc. Treating sleep apnea in patients using phrenic nerve stimulation
US9026228B2 (en) * 2004-10-21 2015-05-05 Medtronic, Inc. Transverse tripole neurostimulation lead, system and method
US20060122661A1 (en) 2004-12-03 2006-06-08 Mandell Lee J Diaphragmatic pacing with activity monitor adjustment
US10537741B2 (en) * 2004-12-03 2020-01-21 Boston Scientific Neuromodulation Corporation System and method for choosing electrodes in an implanted stimulator device
NZ556274A (en) 2004-12-08 2010-05-28 Ventus Medical Inc Respiratory devices and methods of use
US20060130833A1 (en) 2004-12-16 2006-06-22 Magdy Younes Treatment of obstructive sleep apnea
US7869865B2 (en) 2005-01-07 2011-01-11 Biosense Webster, Inc. Current-based position sensing
US8019439B2 (en) 2005-01-11 2011-09-13 Boston Scientific Neuromodulation Corporation Lead assembly and method of making same
US7891085B1 (en) 2005-01-11 2011-02-22 Boston Scientific Neuromodulation Corporation Electrode array assembly and method of making same
US7269459B1 (en) 2005-02-08 2007-09-11 Pacesetter, Inc. Implantable cardiac device with selectable tiered sleep apnea therapies and method
US7255511B2 (en) 2005-02-22 2007-08-14 Dolan Kevin P Releasable dovetail corner joint
US7702385B2 (en) * 2005-11-16 2010-04-20 Boston Scientific Neuromodulation Corporation Electrode contact configurations for an implantable stimulator
US7363086B1 (en) 2005-03-21 2008-04-22 Pacesetter, Inc. Capture verification in respiratory diaphragm stimulation
US20060217791A1 (en) 2005-03-23 2006-09-28 Arrow International, Inc. Multi-lumen catheter having external electrical leads
US7499748B2 (en) 2005-04-11 2009-03-03 Cardiac Pacemakers, Inc. Transvascular neural stimulation device
US7676275B1 (en) * 2005-05-02 2010-03-09 Pacesetter, Inc. Endovascular lead for chronic nerve stimulation
US7561923B2 (en) 2005-05-09 2009-07-14 Cardiac Pacemakers, Inc. Method and apparatus for controlling autonomic balance using neural stimulation
US7617003B2 (en) 2005-05-16 2009-11-10 Cardiac Pacemakers, Inc. System for selective activation of a nerve trunk using a transvascular reshaping lead
US7949412B1 (en) 2005-06-02 2011-05-24 Advanced Bionics, Llc Coated electrode array having uncoated electrode contacts
US7430447B2 (en) * 2005-06-06 2008-09-30 Pacesetter, Inc. Evoked response and impedance measures for monitoring heart failure and respiration
US7553305B2 (en) 2005-06-09 2009-06-30 Enpath Medical, Inc. Push-pull wire anchor
US8036750B2 (en) 2005-06-13 2011-10-11 Cardiac Pacemakers, Inc. System for neural control of respiration
US20070005053A1 (en) 2005-06-30 2007-01-04 Dando Jeremy D Ablation catheter with contoured openings in insulated electrodes
US7879030B2 (en) 2005-07-27 2011-02-01 St. Jude Medical, Atrial Fibrillation Division, Inc. Multipolar, virtual-electrode catheter with at least one surface electrode and method for ablation
US7416552B2 (en) 2005-08-22 2008-08-26 St. Jude Medical, Atrial Fibrillation Division, Inc. Multipolar, multi-lumen, virtual-electrode catheter with at least one surface electrode and method for ablation
US7519426B1 (en) 2005-10-07 2009-04-14 Pacesetter, Inc. Techniques for reducing orthostatic hypotension
US7771388B2 (en) 2005-10-12 2010-08-10 Daniel Olsen Steerable catheter system
WO2007047989A2 (en) * 2005-10-19 2007-04-26 Duke University Electrode systems and related methods for providing therapeutic differential tissue stimulation
US7636600B1 (en) 2005-10-21 2009-12-22 Pacesetter, Inc. Pressure monitoring for apnea prevention and/or therapy
US7616990B2 (en) 2005-10-24 2009-11-10 Cardiac Pacemakers, Inc. Implantable and rechargeable neural stimulator
CA2628417C (en) 2005-11-08 2014-07-08 Custom Medical Applications, Inc. Reinforced catheter with articulated distal tip
US10406366B2 (en) 2006-11-17 2019-09-10 Respicardia, Inc. Transvenous phrenic nerve stimulation system
WO2007061902A2 (en) 2005-11-18 2007-05-31 Cardiac Concepts System and method to modulate phrenic nerve to prevent sleep apnea
US12179014B2 (en) 2005-11-18 2024-12-31 Zoll Respicardia, Inc. Transvenous phrenic nerve stimulation system
US8696656B2 (en) 2005-11-18 2014-04-15 Medtronic Cryocath Lp System and method for monitoring bioimpedance and respiration
JP2009521276A (ja) 2005-12-22 2009-06-04 プロテウス バイオメディカル インコーポレイテッド 植え込み型集積回路
US7672728B2 (en) 2005-12-28 2010-03-02 Cardiac Pacemakers, Inc. Neural stimulator to treat sleep disordered breathing
US8281792B2 (en) 2005-12-31 2012-10-09 John W Royalty Electromagnetic diaphragm assist device and method for assisting a diaphragm function
US7813805B1 (en) 2006-01-11 2010-10-12 Pacesetter, Inc. Subcardiac threshold vagal nerve stimulation
US7763034B2 (en) * 2006-01-24 2010-07-27 Medtronic, Inc. Transobturator lead implantation for pelvic floor stimulation
JP5256048B2 (ja) 2006-02-03 2013-08-07 シネコー・エルエルシー 神経調節のための脈管内デバイス
US7347695B2 (en) 2006-02-03 2008-03-25 Ware Linda M Chronic obstructive pulmonary disease simulator
US20070191908A1 (en) 2006-02-16 2007-08-16 Jacob Doreen K Method and apparatus for stimulating a denervated muscle
US8585753B2 (en) * 2006-03-04 2013-11-19 John James Scanlon Fibrillated biodegradable prosthesis
US7810497B2 (en) 2006-03-20 2010-10-12 Ric Investments, Llc Ventilatory control system
US7900626B2 (en) 2006-04-17 2011-03-08 Daly Robert W Method and system for controlling breathing
WO2007146076A2 (en) 2006-06-07 2007-12-21 Cherik Bulkes Biological tissue stimulator with flexible electrode carrier
WO2007146842A2 (en) 2006-06-08 2007-12-21 Surgical Solutions Llc Medical device with articulating shaft
US20080039916A1 (en) 2006-08-08 2008-02-14 Olivier Colliou Distally distributed multi-electrode lead
US8103341B2 (en) * 2006-08-25 2012-01-24 Cardiac Pacemakers, Inc. System for abating neural stimulation side effects
US8121692B2 (en) 2006-08-30 2012-02-21 Cardiac Pacemakers, Inc. Method and apparatus for neural stimulation with respiratory feedback
US8050765B2 (en) 2006-08-30 2011-11-01 Cardiac Pacemakers, Inc. Method and apparatus for controlling neural stimulation during disordered breathing
US20080065002A1 (en) 2006-09-07 2008-03-13 Neurosystec Corporation Catheter for Localized Drug Delivery and/or Electrical Stimulation
WO2008045877A2 (en) 2006-10-10 2008-04-17 St. Jude Medical, Atrial Fibrillation Division, Inc. Electrode tip and ablation system
US7794407B2 (en) 2006-10-23 2010-09-14 Bard Access Systems, Inc. Method of locating the tip of a central venous catheter
US8388546B2 (en) 2006-10-23 2013-03-05 Bard Access Systems, Inc. Method of locating the tip of a central venous catheter
EP2101873A2 (en) 2006-12-06 2009-09-23 Medtronic, Inc. User interface with toolbar for programming electrical stimulation therapy
US9314618B2 (en) 2006-12-06 2016-04-19 Spinal Modulation, Inc. Implantable flexible circuit leads and methods of use
US8280513B2 (en) 2006-12-22 2012-10-02 Rmx, Llc Device and method to treat flow limitations
US7996092B2 (en) * 2007-01-16 2011-08-09 Ndi Medical, Inc. Devices, systems, and methods employing a molded nerve cuff electrode
US8909341B2 (en) 2007-01-22 2014-12-09 Respicardia, Inc. Device and method for the treatment of breathing disorders and cardiac disorders
CA2676119C (en) 2007-01-29 2021-01-19 Simon Fraser University Transvascular nerve stimulation apparatus and methods
US20080183255A1 (en) 2007-01-30 2008-07-31 Cardiac Pacemakers, Inc. Side port lead delivery system
US20080183264A1 (en) 2007-01-30 2008-07-31 Cardiac Pacemakers, Inc. Electrode configurations for transvascular nerve stimulation
US20080183187A1 (en) 2007-01-30 2008-07-31 Cardiac Pacemakers, Inc. Direct delivery system for transvascular lead
US7917230B2 (en) 2007-01-30 2011-03-29 Cardiac Pacemakers, Inc. Neurostimulating lead having a stent-like anchor
US20080183265A1 (en) 2007-01-30 2008-07-31 Cardiac Pacemakers, Inc. Transvascular lead with proximal force relief
US7949409B2 (en) * 2007-01-30 2011-05-24 Cardiac Pacemakers, Inc. Dual spiral lead configurations
US20080183186A1 (en) 2007-01-30 2008-07-31 Cardiac Pacemakers, Inc. Method and apparatus for delivering a transvascular lead
US8244378B2 (en) 2007-01-30 2012-08-14 Cardiac Pacemakers, Inc. Spiral configurations for intravascular lead stability
US7819883B2 (en) 2007-03-13 2010-10-26 Cardiac Pacemakers, Inc. Method and apparatus for endoscopic access to the vagus nerve
GB0707906D0 (en) 2007-04-24 2007-05-30 Apparatus for detecting the position of a catheter
CN101674859B (zh) 2007-04-27 2015-12-02 马奎特紧急护理公司 用于emg控制的呼吸器的控制单元和显示单元
US10492729B2 (en) 2007-05-23 2019-12-03 St. Jude Medical, Cardiology Division, Inc. Flexible high-density mapping catheter tips and flexible ablation catheter tips with onboard high-density mapping electrodes
WO2008157180A1 (en) 2007-06-13 2008-12-24 E-Pacing, Inc. Implantable devices and methods for stimulation of cardiac and other tissues
EP2170458A1 (en) 2007-06-13 2010-04-07 E- Pacing, Inc. Implantable devices and methods for stimulation of cardiac or other tissues
US9987488B1 (en) 2007-06-27 2018-06-05 Respicardia, Inc. Detecting and treating disordered breathing
EP2164560B8 (en) 2007-06-29 2016-10-12 NewStim, Inc. Systems for cardiac rhythm management using an electrode arrangement
US20090024047A1 (en) 2007-07-20 2009-01-22 Cardiac Pacemakers, Inc. Devices and methods for respiration therapy
US8265736B2 (en) 2007-08-07 2012-09-11 Cardiac Pacemakers, Inc. Method and apparatus to perform electrode combination selection
US9037239B2 (en) 2007-08-07 2015-05-19 Cardiac Pacemakers, Inc. Method and apparatus to perform electrode combination selection
US7994655B2 (en) 2007-08-17 2011-08-09 Inovise Medical, Inc. Mechanical, anatomical heart-pumping assist
US8135471B2 (en) 2007-08-28 2012-03-13 Cardiac Pacemakers, Inc. Method and apparatus for inspiratory muscle stimulation using implantable device
US8485980B2 (en) 2007-09-28 2013-07-16 Maquet Critical Care Ab Electrode positioning
WO2009048610A1 (en) 2007-10-10 2009-04-16 Cardiac Pacemakers, Inc. Respiratory stimulation for treating periodic breathing
WO2009059033A1 (en) 2007-10-30 2009-05-07 Synapse Biomedical, Inc. Method of improving sleep disordered breathing
US8428726B2 (en) 2007-10-30 2013-04-23 Synapse Biomedical, Inc. Device and method of neuromodulation to effect a functionally restorative adaption of the neuromuscular system
EP2992825B1 (en) 2007-11-26 2017-11-01 C.R. Bard Inc. Integrated system for intravascular placement of a catheter
US8406883B1 (en) 2007-12-27 2013-03-26 Boston Scientific Neuromodulation Corporation Lead assembly for electrical stimulation systems and methods of making and using
US20130123891A1 (en) 2008-02-01 2013-05-16 John Swanson High density terminal contacts for stimulation lead and stimulation system employing the same, and method of stimulation lead fabrication
US9199075B1 (en) 2008-02-07 2015-12-01 Respicardia, Inc. Transvascular medical lead
US7925352B2 (en) 2008-03-27 2011-04-12 Synecor Llc System and method for transvascularly stimulating contents of the carotid sheath
US8052607B2 (en) 2008-04-22 2011-11-08 St. Jude Medical, Atrial Fibrillation Division, Inc. Ultrasound imaging catheter with pivoting head
US8315713B2 (en) 2008-04-30 2012-11-20 Medtronic, Inc. Techniques for placing medical leads for electrical stimulation of nerve tissue
US20090275997A1 (en) * 2008-05-01 2009-11-05 Michael Allen Faltys Vagus nerve stimulation electrodes and methods of use
WO2009134459A2 (en) 2008-05-02 2009-11-05 The Johns Hopkins University Portable negative pressure ventilation device and methods and software related thereto
US9409012B2 (en) 2008-06-19 2016-08-09 Cardiac Pacemakers, Inc. Pacemaker integrated with vascular intervention catheter
US8239037B2 (en) 2008-07-06 2012-08-07 Synecor Llc Intravascular implant anchors having remote communication and/or battery recharging capabilities
US8160701B2 (en) 2008-07-08 2012-04-17 Cardiac Pacemakers, Inc. Systems and methods for delivering vagal nerve stimulation
US8734437B2 (en) 2008-07-23 2014-05-27 Boston Scientific Scimed, Inc. Catheter having electrically conductive pathways
JP4545210B2 (ja) 2008-09-11 2010-09-15 日本ライフライン株式会社 除細動カテーテル
EP2364178A1 (en) 2008-10-13 2011-09-14 E- Pacing, Inc. Devices and methods for electrical stimulation of the diaphragm and nerves
US20100114227A1 (en) 2008-10-30 2010-05-06 Pacesetter, Inc. Systems and Methds for Use by an Implantable Medical Device for Controlling Vagus Nerve Stimulation Based on Heart Rate Reduction Curves and Thresholds to Mitigate Heart Failure
US8386053B2 (en) 2008-10-31 2013-02-26 Medtronic, Inc. Subclavian ansae stimulation
EP2346567A4 (en) 2008-11-13 2012-04-25 Proteus Biomedical Inc MULTIPLEX MULTI ELECTRODE NEURO STIMULATION DEVICE
JP2012508622A (ja) 2008-11-13 2012-04-12 プロテウス バイオメディカル インコーポレイテッド 充電式刺激リード、システム、および方法
WO2010056707A1 (en) 2008-11-14 2010-05-20 Cardiac Pacemakers, Inc. Mass attribute detection through phrenic stimulation
US8644939B2 (en) 2008-11-18 2014-02-04 Neurostream Technologies General Partnership Method and device for the detection, identification and treatment of sleep apnea/hypopnea
KR101088806B1 (ko) 2009-01-07 2011-12-01 주식회사 뉴로바이오시스 액정 폴리머를 이용한 미세 전극 어레이 패키지 및 그의 제조 방법
WO2010091435A2 (en) 2009-02-09 2010-08-12 Proteus Biomedical, Inc. Multiplexed multi-electrode neurostimulation devices with integrated circuit having integrated electrodes
US9226688B2 (en) 2009-03-10 2016-01-05 Medtronic Xomed, Inc. Flexible circuit assemblies
US9226689B2 (en) 2009-03-10 2016-01-05 Medtronic Xomed, Inc. Flexible circuit sheet
US20100268311A1 (en) 2009-04-17 2010-10-21 Ralph Cardinal Method for Implanting Electrode on Nerve
US8626292B2 (en) 2009-05-27 2014-01-07 Cardiac Pacemakers, Inc. Respiration sensor processing for phrenic nerve activation detection
US9149642B2 (en) 2009-05-27 2015-10-06 Cardiac Pacemakers, Inc. Method and apparatus for phrenic nerve activation detection with respiration cross-checking
US9532724B2 (en) 2009-06-12 2017-01-03 Bard Access Systems, Inc. Apparatus and method for catheter navigation using endovascular energy mapping
US8694123B2 (en) 2009-06-19 2014-04-08 Medtronic, Inc. Helical electrode arrangements for medical leads
US8340783B2 (en) 2009-06-30 2012-12-25 Medtronic, Inc. Implantable medical device lead with selectively exposed electrodes and reinforcement member
AU2010281644A1 (en) 2009-08-05 2012-02-23 Ndi Medical, Llc Systems and methods for maintaining airway patency
US8374704B2 (en) 2009-09-02 2013-02-12 Cardiac Pacemakers, Inc. Polyisobutylene urethane, urea and urethane/urea copolymers and medical leads containing the same
US8644952B2 (en) 2009-09-02 2014-02-04 Cardiac Pacemakers, Inc. Medical devices including polyisobutylene based polymers and derivatives thereof
US9072899B1 (en) 2009-09-04 2015-07-07 Todd Nickloes Diaphragm pacemaker
US8233987B2 (en) 2009-09-10 2012-07-31 Respicardia, Inc. Respiratory rectification
US9468755B2 (en) 2009-09-30 2016-10-18 Respicardia, Inc. Medical lead with preformed bias
US8617228B2 (en) 2009-10-23 2013-12-31 Medtronic Cryocath Lp Method and system for preventing nerve injury during a medical procedure
CN102821676B (zh) 2010-01-29 2016-09-07 C·R·巴德股份有限公司 牺牲导管
BR112012019354B1 (pt) 2010-02-02 2021-09-08 C.R.Bard, Inc Método para localização de um dispositivo médico implantável
JP5537213B2 (ja) 2010-03-26 2014-07-02 オリンパス株式会社 電気刺激電極組立体
US20110230945A1 (en) 2010-03-19 2011-09-22 Olympus Corporation Electrostimulation system, and electrostimulation electrode assembly and biological implantable electrode therefor
US20110270358A1 (en) 2010-04-30 2011-11-03 Medtronic, Inc. Implantable medical device programming using gesture-based control
US10631912B2 (en) 2010-04-30 2020-04-28 Medtronic Xomed, Inc. Interface module for use with nerve monitoring and electrosurgery
US8755889B2 (en) 2010-04-30 2014-06-17 Medtronic, Inc. Method and apparatus to enhance therapy during stimulation of vagus nerve
WO2011153027A1 (en) 2010-06-03 2011-12-08 Cardiac Pacemakers, Inc. System for controlling target of neurostimulation using temporal parameters
EP2575961B1 (en) 2010-06-03 2018-08-29 Cardiac Pacemakers, Inc. System for spatially selective vagus nerve stimulation
JP4940332B2 (ja) 2010-06-15 2012-05-30 日本ライフライン株式会社 カテーテル
US20120130217A1 (en) 2010-11-23 2012-05-24 Kauphusman James V Medical devices having electrodes mounted thereon and methods of manufacturing therefor
KR101889567B1 (ko) 2010-06-30 2018-08-17 메드-엘 엘렉트로메디지니쉐 게라에테 게엠베하 귀 임플란트 전극 및 제조 방법
AU2011282294B9 (en) 2010-07-19 2014-09-25 Cardiac Pacemakers, Inc. Minimally invasive lead system for vagus nerve stimulation
CA2802333A1 (en) 2010-07-29 2012-02-02 Boston Scientific Neuromodulation Corporation Systems and methods for making and using electrical stimulation systems having multi-lead-element lead bodies
EP2600936B1 (en) 2010-08-06 2018-09-19 Cardiac Pacemakers, Inc. User interface system for use with multipolar pacing leads
US8934956B2 (en) 2010-08-31 2015-01-13 Interventional Autonomics Corporation Intravascular electrodes and anchoring devices for transvascular stimulation
US20120078320A1 (en) 2010-09-29 2012-03-29 Medtronic, Inc. Prioritized programming of multi-electrode pacing leads
KR101304338B1 (ko) 2010-10-21 2013-09-11 주식회사 엠아이텍 액정폴리머 기반의 전광극 신경 인터페이스 및 그 제조 방법
WO2012058461A1 (en) 2010-10-29 2012-05-03 C.R.Bard, Inc. Bioimpedance-assisted placement of a medical device
US8391956B2 (en) 2010-11-18 2013-03-05 Robert D. Zellers Medical device location systems, devices and methods
US8560086B2 (en) 2010-12-02 2013-10-15 St. Jude Medical, Atrial Fibrillation Division, Inc. Catheter electrode assemblies and methods of construction therefor
US8781582B2 (en) 2011-01-19 2014-07-15 Medtronic, Inc. Vagal stimulation
US8718763B2 (en) 2011-01-19 2014-05-06 Medtronic, Inc. Vagal stimulation
US8706223B2 (en) 2011-01-19 2014-04-22 Medtronic, Inc. Preventative vagal stimulation
US8781583B2 (en) 2011-01-19 2014-07-15 Medtronic, Inc. Vagal stimulation
US8725259B2 (en) 2011-01-19 2014-05-13 Medtronic, Inc. Vagal stimulation
ES2813411T3 (es) 2011-01-25 2021-03-23 Apellis Holdings Llc Aparato y métodos para ayudar a respirar
US9550041B2 (en) 2011-02-04 2017-01-24 Advanced Pain Center, Llc. Continuous single wire steerable catheter
US9744349B2 (en) 2011-02-10 2017-08-29 Respicardia, Inc. Medical lead and implantation
US8430864B2 (en) 2011-02-16 2013-04-30 Biosense Webster, Inc. Catheter with multiple deflections
US8504158B2 (en) 2011-05-09 2013-08-06 Medtronic, Inc. Phrenic nerve stimulation during cardiac refractory period
US9615759B2 (en) 2011-07-12 2017-04-11 Bard Access Systems, Inc. Devices and methods for ECG guided vascular access
US20130018427A1 (en) 2011-07-15 2013-01-17 Khiem Pham Screw Implants For Bone Fusion
US20130030497A1 (en) 2011-07-27 2013-01-31 Medtronic, Inc. Nerve stimulator for reduced muscle fatigue
US8706235B2 (en) 2011-07-27 2014-04-22 Medtronic, Inc. Transvenous method to induce respiration
US8805511B2 (en) 2011-07-27 2014-08-12 Medtronic, Inc. Method and apparatus to detect subcerebral ischemia
US8478413B2 (en) 2011-07-27 2013-07-02 Medtronic, Inc. Bilateral phrenic nerve stimulation with reduced dyssynchrony
US9861817B2 (en) 2011-07-28 2018-01-09 Medtronic, Inc. Medical device to provide breathing therapy
US8509902B2 (en) 2011-07-28 2013-08-13 Medtronic, Inc. Medical device to provide breathing therapy
US10201385B2 (en) 2011-09-01 2019-02-12 Biosense Webster (Israel) Ltd. Catheter adapted for direct tissue contact
US9724018B2 (en) 2011-10-27 2017-08-08 Medtronic Cryocath Lp Method for monitoring phrenic nerve function
US8897879B2 (en) 2011-11-04 2014-11-25 Medtronic, Inc. Method and apparatus for therapies of the cardiovascular and cardiorenal system
EP2775899B1 (en) 2011-11-07 2017-08-23 Medtronic Ardian Luxembourg S.à.r.l. Endovascular nerve monitoring devices and associated systems
US9956396B2 (en) 2012-02-08 2018-05-01 Medtronic Bakken Research Center B.V. Thin film for a lead for brain applications
IN2014MN01970A (enExample) 2012-03-05 2015-07-03 Univ Fraser Simon
US8903509B2 (en) 2012-03-21 2014-12-02 Cardiac Pacemakers Inc. Systems and methods for stimulation of vagus nerve
US10413203B2 (en) 2012-03-27 2019-09-17 Cardiac Pacemakers, Inc. Baseline determination for phrenic nerve stimulation detection
WO2013165920A1 (en) 2012-04-29 2013-11-07 Synecor Llc Intravascular electrode arrays for neuromodulation
WO2013165584A1 (en) 2012-05-04 2013-11-07 St. Jude Medical, Atrial Fibrillation Division, Inc. System and method for controlling delivery of ablation energy to tissue
AU2013266508A1 (en) 2012-05-25 2014-11-06 Boston Scientific Neuromodulation Corporation Methods for stimulating the dorsal root ganglion with a lead having segmented electrodes
AU2013280184B2 (en) 2012-06-21 2017-08-24 Lungpacer Medical Inc. Transvascular diaphragm pacing systems and methods of use
WO2014008171A1 (en) 2012-07-02 2014-01-09 Medisci L.L.C. Method and device for respiratory and cardiorespiratory support
US8504161B1 (en) 2012-08-07 2013-08-06 Medtronic, Inc. Modulate vagal signals to reduce inflammation
US10137262B2 (en) 2012-08-20 2018-11-27 Koninklijke Philips N.V. Synchronizing mechanical in-exsufflation and diaphragmatic pacing
EP2722071A1 (en) 2012-10-16 2014-04-23 Sapiens Steering Brain Stimulation B.V. A probe, especially a probe for neural applications
US20140121716A1 (en) 2012-10-31 2014-05-01 Medtronic, Inc. High voltage therapy diversion algorithms
WO2014071386A1 (en) 2012-11-05 2014-05-08 Regents Of The University Of Minnesota Non-invasive lung pacing
CN102949770B (zh) 2012-11-09 2015-04-22 张红璇 一种体外膈肌起搏与呼吸机协同送气的方法及其装置
US9072864B2 (en) 2012-11-28 2015-07-07 Ad-Tech Medical Instrument Corporation Catheter with depth electrode for dual-purpose use
US9884179B2 (en) 2012-12-05 2018-02-06 Bbattelle Memorial Institute Neural sleeve for neuromuscular stimulation, sensing and recording
US9884178B2 (en) 2012-12-05 2018-02-06 Battelle Memorial Institute Neuromuscular stimulation cuff
US10335592B2 (en) 2012-12-19 2019-07-02 Viscardia, Inc. Systems, devices, and methods for improving hemodynamic performance through asymptomatic diaphragm stimulation
EP2934668B1 (en) 2012-12-19 2018-08-22 VisCardia, Inc. Hemodynamic performance enhancement through asymptomatic diaphragm stimulation
US9485873B2 (en) 2013-03-15 2016-11-01 Lawrence Livermore National Security, Llc Depositing bulk or micro-scale electrodes
EP2818104B1 (de) 2013-06-25 2016-01-06 VascoMed GmbH Katheter und Verfahren zur Herstellung desselben
US9427566B2 (en) 2013-08-14 2016-08-30 Syntilla Medical LLC Implantable neurostimulation lead for head pain
WO2015030734A1 (en) 2013-08-27 2015-03-05 Advanced Bionics Ag Thermoformed electrode arrays
US9504837B2 (en) 2013-10-25 2016-11-29 Medtronic, Inc. Automated phrenic nerve stimulation and pacing capture threshold test
US9205258B2 (en) 2013-11-04 2015-12-08 ElectroCore, LLC Nerve stimulator system
EP3760276B1 (en) 2013-11-22 2023-08-30 Lungpacer Medical Inc. Apparatus for assisted breathing by transvascular nerve stimulation
WO2015106116A1 (en) 2014-01-10 2015-07-16 Boston Scientific Scimed, Inc. Medical devices with flexible circuit assemblies
WO2015109401A1 (en) 2014-01-21 2015-07-30 Simon Fraser University Systems and related methods for optimization of multi-electrode nerve pacing
US9498631B2 (en) 2014-02-20 2016-11-22 Medtronic, Inc. Automated phrenic nerve stimulation and pacing capture threshold test
US9844644B2 (en) 2014-03-05 2017-12-19 Oscor Inc. Intravascular sheath with mapping capabilities to deliver therapeutic devices to a targeted location within a blood vessel
US12070601B2 (en) 2014-03-28 2024-08-27 Pinnacle Bionics. Inc. Stimulation system for exercising diaphragm and method of operation thereof
US10194978B2 (en) 2014-06-13 2019-02-05 Medtronic Cryocath Lp Supporting catheter for use for phrenic nerve pacing
KR101654801B1 (ko) 2014-08-08 2016-09-07 서울대학교산학협력단 액정 폴리머 기반의 신경 임플란트용 전극 어레이와 패키지 및 그 제조 방법
WO2016033245A1 (en) 2014-08-26 2016-03-03 Rmx, Llc Devices and methods for reducing intrathoracic pressure
US9474894B2 (en) 2014-08-27 2016-10-25 Aleva Neurotherapeutics Deep brain stimulation lead
EP3185751A1 (en) 2014-08-29 2017-07-05 Incyphae Inc. Method and apparatus for enhancing nervous function
US10507321B2 (en) 2014-11-25 2019-12-17 Medtronic Bakken Research Center B.V. Multilayer structure and method of manufacturing a multilayer structure
US10622107B2 (en) 2015-02-13 2020-04-14 Medtronic, Inc. Tools for medical device configuration
US20160331326A1 (en) 2015-02-13 2016-11-17 National University Of Singapore Flexible neural strip electrodes, flexible neural ribbon electrodes and compartment based embedded nerve tissue electrode interfaces for peripheral nerves
EP3064131A1 (en) 2015-03-03 2016-09-07 BIOTRONIK SE & Co. KG Combined vagus-phrenic nerve stimulation apparatus
US9872989B2 (en) 2015-04-02 2018-01-23 The Florida International University Board Of Trustees System and method for neuromorphic controlled adaptive pacing of respiratory muscles and nerves
CN108348755B (zh) * 2015-07-24 2021-09-24 心脏起搏器股份公司 用于刺激部位选择的系统和方法
AU2016297965B2 (en) 2015-07-30 2019-04-04 Boston Scientific Neuromodulation Corporation User interface for custom patterned electrical stimulation
ES2977539T3 (es) 2015-12-14 2024-08-26 Stimdia Medical Inc Estimulación eléctrica para la preservación y restablecimiento de la función del diafragma
US10369361B2 (en) 2016-04-29 2019-08-06 Viscardia, Inc. Leads for implantable medical device that affects pressures within the intrathoracic cavity through diaphragmatic stimulation
US10695564B2 (en) 2016-06-02 2020-06-30 Battelle Memorial Institute Flexible sheet for neuromuscular stimulation
WO2017210672A1 (en) 2016-06-03 2017-12-07 The Cleveland Clinic Foundation Systems and methods for monitoring a depth of neuromuscular blockade
US10207103B2 (en) 2016-07-05 2019-02-19 Pacesetter, Inc. Implantable thin film devices
US10898262B2 (en) 2016-10-25 2021-01-26 Biosense Webster (Israel) Ltd. Catheter distal end made of plastic tube and flexible printed circuit boards
US10293164B2 (en) 2017-05-26 2019-05-21 Lungpacer Medical Inc. Apparatus and methods for assisted breathing by transvascular nerve stimulation
US10195429B1 (en) 2017-08-02 2019-02-05 Lungpacer Medical Inc. Systems and methods for intravascular catheter positioning and/or nerve stimulation
CA3090028A1 (en) 2018-02-06 2019-08-15 Stimit Ag Ventilation machine and method of ventilating a patient

Also Published As

Publication number Publication date
US9108059B2 (en) 2015-08-18
US9950167B2 (en) 2018-04-24
US20190201690A1 (en) 2019-07-04
US20160367816A1 (en) 2016-12-22
US9968785B2 (en) 2018-05-15
EP2107920A4 (en) 2010-06-02
US20150306397A1 (en) 2015-10-29
US20250170402A1 (en) 2025-05-29
US20100036451A1 (en) 2010-02-11
CA3000408A1 (en) 2008-08-07
US9108058B2 (en) 2015-08-18
US20200147377A1 (en) 2020-05-14
DK2107920T3 (da) 2013-10-21
US9220898B2 (en) 2015-12-29
US9566436B2 (en) 2017-02-14
US11027130B2 (en) 2021-06-08
WO2008092246A1 (en) 2008-08-07
EP2107920B1 (en) 2013-07-10
US9168377B2 (en) 2015-10-27
US20150012070A1 (en) 2015-01-08
CA2877177A1 (en) 2008-08-07
US9026231B2 (en) 2015-05-05
CA3000408C (en) 2024-04-02
US10792499B2 (en) 2020-10-06
ES2430613T3 (es) 2013-11-21
HK1137682A1 (en) 2010-08-06
US20140039286A1 (en) 2014-02-06
US20140343632A1 (en) 2014-11-20
US10561843B2 (en) 2020-02-18
JP5465538B2 (ja) 2014-04-09
US20180361149A1 (en) 2018-12-20
US20210316140A1 (en) 2021-10-14
US20170120057A1 (en) 2017-05-04
US8571662B2 (en) 2013-10-29
US20200222694A1 (en) 2020-07-16
US20140343636A1 (en) 2014-11-20
US10864374B2 (en) 2020-12-15
US20160367815A1 (en) 2016-12-22
EP2107920A1 (en) 2009-10-14
US20180296835A1 (en) 2018-10-18
CA2676119A1 (en) 2008-08-07
US10022546B2 (en) 2018-07-17
US12268877B2 (en) 2025-04-08
JP2010516353A (ja) 2010-05-20
CA2877177C (en) 2018-05-22
US20140343635A1 (en) 2014-11-20
US10765867B2 (en) 2020-09-08

Similar Documents

Publication Publication Date Title
US12268877B2 (en) Transvascular nerve stimulation apparatus and methods
US8369954B2 (en) System and method for transvascularly stimulating contents of the carotid sheath
HK1137682B (en) Transvascular nerve stimulation apparatus

Legal Events

Date Code Title Description
EEER Examination request

Effective date: 20130108