CA2674007A1 - Process for manufacturing vaccines - Google Patents
Process for manufacturing vaccines Download PDFInfo
- Publication number
- CA2674007A1 CA2674007A1 CA002674007A CA2674007A CA2674007A1 CA 2674007 A1 CA2674007 A1 CA 2674007A1 CA 002674007 A CA002674007 A CA 002674007A CA 2674007 A CA2674007 A CA 2674007A CA 2674007 A1 CA2674007 A1 CA 2674007A1
- Authority
- CA
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- Prior art keywords
- saccharide
- protein
- amino
- aliquot
- protein carrier
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Virology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Toxicology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0700136.5 | 2007-01-04 | ||
| GBGB0700136.5A GB0700136D0 (en) | 2007-01-04 | 2007-01-04 | Process for manufacturing vaccines |
| PCT/EP2008/050011 WO2008081014A2 (en) | 2007-01-04 | 2008-01-02 | Process for manufacturing vaccines |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2674007A1 true CA2674007A1 (en) | 2008-07-10 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002674007A Abandoned CA2674007A1 (en) | 2007-01-04 | 2008-01-02 | Process for manufacturing vaccines |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US8858955B2 (enExample) |
| EP (1) | EP2099487B1 (enExample) |
| JP (1) | JP5683815B2 (enExample) |
| CA (1) | CA2674007A1 (enExample) |
| ES (1) | ES2546186T3 (enExample) |
| GB (1) | GB0700136D0 (enExample) |
| WO (1) | WO2008081014A2 (enExample) |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| PT1946769E (pt) * | 2000-06-29 | 2012-06-27 | Smithkline Beecham Biolog | Composição de vacina multivalente com dose reduzida de haemophilus influenzae de tipo b |
| US7527797B1 (en) | 2000-09-01 | 2009-05-05 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Vibrio cholerae 0139 conjugate vaccines |
| ATE536884T1 (de) * | 2005-06-27 | 2011-12-15 | Glaxosmithkline Biolog Sa | Immunogene zusammensetzung |
| US20180221466A9 (en) * | 2006-06-12 | 2018-08-09 | Glaxosmithkline Biologicals S.A. | Use of alpha-toxin for treating and preventing staphylococcus infections |
| EP2666784B1 (en) | 2007-08-31 | 2017-04-05 | University Of Chicago | Methods and compositions related to immunizing against staphylococcal lung diseases and conditions |
| US9181329B2 (en) | 2007-08-31 | 2015-11-10 | The University Of Chicago | Methods and compositions related to immunizing against Staphylococcal lung diseases and conditions |
| WO2010014304A1 (en) | 2008-07-29 | 2010-02-04 | University Of Chicago | Compositions and methods related to staphylococcal bacterium proteins |
| CA2748149C (en) * | 2008-12-24 | 2018-03-06 | Netherlands Vaccine Institute | Modified steptococcus pneumonia pneumolysin (ply) polypeptides |
| HRP20160274T1 (hr) | 2009-04-03 | 2016-04-08 | University Of Chicago | Pripravci i metode vezane za varijante proteina a (spa) |
| ES2565377T3 (es) * | 2009-04-14 | 2016-04-04 | Glaxosmithkline Biologicals Sa | Composiciones para inmunización contra Staphylococcus aureus |
| RU2580299C2 (ru) | 2009-06-29 | 2016-04-10 | Дженосеа Биосайенсиз, Инк. | Вакцины и композиции, направленные против streptococcus pneumoniae |
| PL2493498T3 (pl) | 2009-10-30 | 2017-08-31 | Glaxosmithkline Biologicals Sa | Oczyszczanie sacharydów otoczkowych staphylococcus aureus typu 5 i typu 8 |
| CN102939105B (zh) | 2009-12-22 | 2016-11-16 | 赛诺菲巴斯德有限公司 | 免疫原性组合物和相关的方法 |
| ES2655701T3 (es) | 2010-07-02 | 2018-02-21 | The University Of Chicago | Composiciones y métodos relacionados con variantes de la proteína A (SpA) |
| EP2665490B1 (en) | 2011-01-20 | 2020-03-04 | Genocea Biosciences, Inc. | Vaccines and compositions against streptococcus pneumoniae |
| US8945588B2 (en) | 2011-05-06 | 2015-02-03 | The University Of Chicago | Methods and compositions involving protective staphylococcal antigens, such as EBH polypeptides |
| NZ702285A (en) * | 2012-04-26 | 2016-07-29 | Univ Chicago | Staphylococcal coagulase antigens and methods of their use |
| KR20170030635A (ko) * | 2014-07-18 | 2017-03-17 | 잇빤 자이단호진 가가쿠오요비겟세이료호겐쿠쇼 | 바이러스 유사 입자를 포함하는 백신 |
| US9107906B1 (en) | 2014-10-28 | 2015-08-18 | Adma Biologics, Inc. | Compositions and methods for the treatment of immunodeficiency |
| US10881723B2 (en) | 2016-01-15 | 2021-01-05 | Km Biologics Co., Ltd. | Vaccine containing immobilized virus particles |
| WO2017137954A2 (en) * | 2016-02-12 | 2017-08-17 | The University Of Chicago | Compositions and methods related to antibodies that neutralize coagulase activity during staphylococcus aureus disease |
| MX2019002489A (es) | 2016-09-02 | 2019-10-21 | Sanofi Pasteur Inc | Vacuna contra neisseria meningitidis. |
| EP4588521A3 (en) | 2016-12-30 | 2025-10-22 | Vaxcyte, Inc. | Polypeptide-antigen conjugates with non-natural amino acids |
| US11951165B2 (en) | 2016-12-30 | 2024-04-09 | Vaxcyte, Inc. | Conjugated vaccine carrier proteins |
| US10259865B2 (en) | 2017-03-15 | 2019-04-16 | Adma Biologics, Inc. | Anti-pneumococcal hyperimmune globulin for the treatment and prevention of pneumococcal infection |
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| DE3071552D1 (en) | 1979-09-21 | 1986-05-22 | Hitachi Ltd | Semiconductor switch |
| DE3040825A1 (de) * | 1980-10-30 | 1982-09-09 | Dr. Karl Thomae Gmbh, 7950 Biberach | Neues tridekapeptid, verfahren zu seiner herstellung und verwendung |
| US4673574A (en) | 1981-08-31 | 1987-06-16 | Anderson Porter W | Immunogenic conjugates |
| US4695624A (en) | 1984-05-10 | 1987-09-22 | Merck & Co., Inc. | Covalently-modified polyanionic bacterial polysaccharides, stable covalent conjugates of such polysaccharides and immunogenic proteins with bigeneric spacers, and methods of preparing such polysaccharides and conjugates and of confirming covalency |
| IT1187753B (it) | 1985-07-05 | 1987-12-23 | Sclavo Spa | Coniugati glicoproteici ad attivita' immunogenica trivalente |
| JPH0776236B2 (ja) * | 1988-04-13 | 1995-08-16 | 富士写真フイルム株式会社 | 蛋白質修飾物 |
| US5180815A (en) * | 1988-04-13 | 1993-01-19 | Fuji Photo Film Co., Ltd. | Modified protein for carrying hapten |
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| EP0482068A1 (en) | 1989-07-14 | 1992-04-29 | American Cyanamid Company | Cytokine and hormone carriers for conjugate vaccines |
| IT1237764B (it) | 1989-11-10 | 1993-06-17 | Eniricerche Spa | Peptidi sintetici utili come carriers universali per la preparazione di coniugati immunogenici e loro impiego per lo sviluppo di vaccini sintetici. |
| DE69113564T2 (de) | 1990-08-13 | 1996-05-30 | American Cyanamid Co | Faser-Hemagglutinin von Bordetella pertussis als Träger für konjugierten Impfstoff. |
| US5153312A (en) | 1990-09-28 | 1992-10-06 | American Cyanamid Company | Oligosaccharide conjugate vaccines |
| CA2059692C (en) | 1991-01-28 | 2004-11-16 | Peter J. Kniskern | Pneumoccoccal polysaccharide conjugate vaccine |
| NZ249704A (en) | 1992-02-11 | 1996-11-26 | Jackson H M Found Military Med | A two carrier immunogenic construct comprising a 70+ kd molecule conjugated to at least 1 t-dependent antigen, preparation, compositions containing the construct |
| IT1262896B (it) | 1992-03-06 | 1996-07-22 | Composti coniugati formati da proteine heat shock (hsp) e oligo-poli- saccaridi, loro uso per la produzione di vaccini. | |
| IL102687A (en) | 1992-07-30 | 1997-06-10 | Yeda Res & Dev | Conjugates of poorly immunogenic antigens and synthetic pepide carriers and vaccines comprising them |
| ES2210262T3 (es) | 1993-09-22 | 2004-07-01 | Henry M. Jackson Foundation For The Advancement Of Military Medicine | Procedimiento que permite activar un glucido soluble con la ayuda de nuevos reactivos cianilantes para producir estructuras inmunogenas. |
| WO1996029094A1 (en) | 1995-03-22 | 1996-09-26 | Andrew Lees | Producing immunogenic constructs using soluble carbohydrates activated via organic cyanylating reagents |
| PT1090642E (pt) | 1995-06-07 | 2008-09-09 | Glaxosmithkline Biolog Sa | Vacinas compreendendo um conjugado de antigénio polissacarídico - proteína veículo e proteína veículo livre |
| WO1998026799A1 (en) | 1996-12-18 | 1998-06-25 | The Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services | Conjugate vaccine for salmonella paratyphi a |
| GB9713156D0 (en) | 1997-06-20 | 1997-08-27 | Microbiological Res Authority | Vaccines |
| US5965714A (en) * | 1997-10-02 | 1999-10-12 | Connaught Laboratories, Inc. | Method for the covalent attachment of polysaccharides to protein molecules |
| CA2329897A1 (en) * | 1998-04-28 | 1999-11-04 | Galenica Pharmaceuticals, Inc. | Polysaccharide-antigen conjugates |
| TWI281403B (en) | 1999-03-19 | 2007-05-21 | Smithkline Beecham Biolog | Vaccine |
| AU781027B2 (en) | 1999-04-09 | 2005-04-28 | Department Of Health & Human Services | Recombinant toxin a protein carrier for polysaccharide conjugate vaccines |
| GB0007432D0 (en) | 2000-03-27 | 2000-05-17 | Microbiological Res Authority | Proteins for use as carriers in conjugate vaccines |
| WO2002091998A2 (en) | 2001-05-11 | 2002-11-21 | Aventis Pasteur, Inc. | Novel meningitis conjugate vaccine |
| GB0115176D0 (en) | 2001-06-20 | 2001-08-15 | Chiron Spa | Capular polysaccharide solubilisation and combination vaccines |
| US20030113350A1 (en) * | 2001-09-19 | 2003-06-19 | Fattom Ali I. | Glycoconjugate vaccines for use in immune-compromised populations |
| DK2255826T3 (en) | 2002-08-02 | 2016-06-20 | Glaxosmithkline Biologicals Sa | Neisserial vaccine compositions comprising a combination of antigens. |
| NZ561879A (en) * | 2003-03-07 | 2009-05-31 | Wyeth Corp | Polysaccharide - staphylococcal surface adhesin carrier protein conjugates for immunization against nosocomial infections |
| EP2893938B1 (en) * | 2004-09-22 | 2019-03-06 | GlaxoSmithKline Biologicals SA | Immunogenic composition for use in vaccination against Staphylococcei |
| GB0428394D0 (en) * | 2004-12-24 | 2005-02-02 | Chiron Srl | Saccharide conjugate vaccines |
| ATE536884T1 (de) | 2005-06-27 | 2011-12-15 | Glaxosmithkline Biolog Sa | Immunogene zusammensetzung |
| US7491517B2 (en) | 2006-07-19 | 2009-02-17 | Jeeri R Reddy | Method of producing meningococcal meningitis vaccine for Neisseria meningitidis serotypes A,C,Y, and W-135 |
| US7935407B2 (en) * | 2009-02-23 | 2011-05-03 | Tsung-Wei Chen | Decorations |
-
2007
- 2007-01-04 GB GBGB0700136.5A patent/GB0700136D0/en not_active Ceased
-
2008
- 2008-01-02 WO PCT/EP2008/050011 patent/WO2008081014A2/en not_active Ceased
- 2008-01-02 US US12/521,797 patent/US8858955B2/en not_active Expired - Fee Related
- 2008-01-02 ES ES08707820.0T patent/ES2546186T3/es active Active
- 2008-01-02 EP EP08707820.0A patent/EP2099487B1/en not_active Not-in-force
- 2008-01-02 JP JP2009544404A patent/JP5683815B2/ja not_active Expired - Fee Related
- 2008-01-02 CA CA002674007A patent/CA2674007A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20100143399A1 (en) | 2010-06-10 |
| WO2008081014A3 (en) | 2008-08-21 |
| EP2099487B1 (en) | 2015-06-24 |
| ES2546186T3 (es) | 2015-09-21 |
| JP2010514817A (ja) | 2010-05-06 |
| JP5683815B2 (ja) | 2015-03-11 |
| EP2099487A2 (en) | 2009-09-16 |
| GB0700136D0 (en) | 2007-02-14 |
| WO2008081014A2 (en) | 2008-07-10 |
| US8858955B2 (en) | 2014-10-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| EEER | Examination request |
Effective date: 20121213 |
|
| FZDE | Discontinued |
Effective date: 20180103 |