CA2671569A1 - Means for the treatment of acute and chronic disorders of cerebral circulation, including insult, based on hydrogenated pyrido (4, 3-b) indoles (variants), pharmacological means based thereon and method for the use thereof - Google Patents
Means for the treatment of acute and chronic disorders of cerebral circulation, including insult, based on hydrogenated pyrido (4, 3-b) indoles (variants), pharmacological means based thereon and method for the use thereof Download PDFInfo
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- CA2671569A1 CA2671569A1 CA002671569A CA2671569A CA2671569A1 CA 2671569 A1 CA2671569 A1 CA 2671569A1 CA 002671569 A CA002671569 A CA 002671569A CA 2671569 A CA2671569 A CA 2671569A CA 2671569 A1 CA2671569 A1 CA 2671569A1
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Classifications
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Epidemiology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| RU2006143332 | 2006-12-07 | ||
| RU2006143332/15A RU2340342C2 (ru) | 2006-12-07 | 2006-12-07 | СРЕДСТВО ДЛЯ ЛЕЧЕНИЯ ОСТРЫХ И ХРОНИЧЕСКИХ НАРУШЕНИЙ МОЗГОВОГО КРОВООБРАЩЕНИЯ, В ТОМ ЧИСЛЕ ИНСУЛЬТА, НА ОСНОВЕ ГИДРИРОВАННЫХ ПИРИДО[4,3-b]ИНДОЛОВ (ВАРИАНТЫ), ФАРМАКОЛОГИЧЕСКОЕ СРЕДСТВО НА ЕГО ОСНОВЕ И СПОСОБ ЕГО ПРИМЕНЕНИЯ |
| PCT/US2007/024626 WO2008073231A1 (en) | 2006-12-07 | 2007-11-30 | Means for the treatment of acute and chronic disorders of cerebral circulation, including insult, based on hydrogenated pyrido (4, 3-b) indoles (variants), pharmacological means based thereon and method for the use thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2671569A1 true CA2671569A1 (en) | 2008-06-19 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002671569A Abandoned CA2671569A1 (en) | 2006-12-07 | 2007-11-30 | Means for the treatment of acute and chronic disorders of cerebral circulation, including insult, based on hydrogenated pyrido (4, 3-b) indoles (variants), pharmacological means based thereon and method for the use thereof |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20110112132A1 (enExample) |
| EP (1) | EP2101578A4 (enExample) |
| JP (1) | JP2010511701A (enExample) |
| AU (1) | AU2007332878A1 (enExample) |
| CA (1) | CA2671569A1 (enExample) |
| RU (1) | RU2340342C2 (enExample) |
| WO (1) | WO2008073231A1 (enExample) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2010003149A (es) | 2007-09-20 | 2010-11-10 | D2E Llc | Derivados que contienen fluor de pirido[4,3-b]indoles hidrogenados con propiedades neuroprotectoras y de mejoramiento de cognicion, proceso de preparacion y uso. |
| RU2007139634A (ru) | 2007-10-25 | 2009-04-27 | Сергей Олегович Бачурин (RU) | Новые тиазол-, триазол- или оксадиазол-содержащие тетрациклические соединения |
| RU2544856C2 (ru) | 2008-01-25 | 2015-03-20 | Сергей Олегович Бачурин | НОВЫЕ ПРОИЗВОДНЫЕ 2,3,4,5-ТЕТРАГИДРО-1-ПИРИДО[4,3-b]ИНДОЛА И СПОСОБЫ ИХ ПРИМЕНЕНИЯ |
| WO2009120717A2 (en) | 2008-03-24 | 2009-10-01 | Medivation Technologies, Inc. | Pyrido [3, 4-b] indoles and methods of use |
| CL2009000725A1 (es) | 2008-03-24 | 2009-05-29 | Medivation Technologies Inc | Compuestos derivados de heterociclos con uniones puente sustituidos, moduladores de receptores adrenergicos, de serotonina, de dopamina y de histaminas; composicion farmaceutica; kit farmaceutico; y su uso en el tratamiento del trastorno cognitivo y trastorno psicotico. |
| CA2742322A1 (en) | 2008-10-31 | 2010-05-06 | Medivation Technologies, Inc. | Azepino[4,5-b]indoles and methods of use |
| CA2742320A1 (en) | 2008-10-31 | 2010-05-06 | Medivation Technologies, Inc. | Pyrido[4,3-b]indoles containing rigid moieties |
| WO2010093425A1 (en) | 2009-02-11 | 2010-08-19 | Sepracor Inc. | Histamine h3 inverse agonists and antagonists and methods of use thereof |
| CN102480955B (zh) | 2009-04-29 | 2015-08-05 | 梅迪维新技术公司 | 吡啶并[4,3-b]吲哚类和使用方法 |
| CA2760516A1 (en) | 2009-04-29 | 2011-02-17 | Medivation Technologies, Inc. | Pyrido[4,3-b]indoles and methods of use |
| EP2480081A4 (en) | 2009-09-23 | 2013-03-06 | Medivation Technologies Inc | Bridged heterocyclic compounds and methods for their use |
| WO2011038161A1 (en) | 2009-09-23 | 2011-03-31 | Medivation Technologies, Inc. | Pyrido[4,3-b]indoles and methods of use |
| US9079904B2 (en) * | 2009-09-23 | 2015-07-14 | Medivation Technologies, Inc. | Pyrido[3,4-B]indoles and methods of use |
| WO2011103460A1 (en) | 2010-02-18 | 2011-08-25 | Medivation Technologies, Inc. | Fused tetracyclic pyrido[4,3-b]indole and pyrido[3,4-b]ondole derivatives and methods of use |
| US9034865B2 (en) | 2010-02-18 | 2015-05-19 | Medivation Technologies, Inc. | Pyrido [4,3-B] indole and pyrido [3,4-B] indole derivatives and methods of use |
| WO2011103485A1 (en) | 2010-02-18 | 2011-08-25 | Medivation Technologies, Inc. | Fused tetracyclic pyrido[4,3-b]indole and pyrido[3,4-b]indole derivatives and methods of use |
| WO2011103430A1 (en) | 2010-02-19 | 2011-08-25 | Medivation Technologies, Inc. | Pyrido[4,3-b]indole and pyrido[3,4-b]indole derivatives and methods of use |
| WO2012112964A2 (en) | 2011-02-18 | 2012-08-23 | Medivation Technologies, Inc. | PYRIDO[4,3-b]INDOLE AND PYRIDO[3,4-b]INDOLE DERIVATIVES AND METHODS OF USE |
| US9434747B2 (en) | 2011-02-18 | 2016-09-06 | Medivation Technologies, Inc. | Methods of treating diabetes |
| US9199985B2 (en) | 2011-02-18 | 2015-12-01 | Medivation Technologies, Inc. | Compounds and methods for treatment of hypertension |
| US8791132B2 (en) | 2011-02-18 | 2014-07-29 | Medivation Technologies, Inc. | Compounds and methods for treatment of hypertension |
| RU2477131C1 (ru) * | 2012-01-17 | 2013-03-10 | Алиса Владимировна Алесенко | СРЕДСТВО ДЛЯ НЕЙТРАЛИЗАЦИИ ТОКСИЧЕСКОГО ДЕЙСТВИЯ ФАКТОРА НЕКРОЗА ОПУХОЛИ НА ОСНОВЕ ГИДРИРОВАННЫХ ПИРИДО (4,3-b) ИНДОЛОВ, ФАРМАКОЛОГИЧЕСКОЕ СРЕДСТВО НА ЕГО ОСНОВЕ И СПОСОБ ЛЕЧЕНИЯ АУТОИММУННЫХ ЗАБОЛЕВАНИЙ НА ОСНОВЕ НЕЙТРАЛИЗАЦИИ ТОКСИЧЕСКОГО ДЕЙСТВИЯ ФАКТОРА НЕКРОЗА ОПУХОЛИ |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1118990A (zh) * | 1993-03-08 | 1996-03-20 | 藤泽药品工业株式会社 | 治疗或预防脑血管疾病药物 |
| RU2140417C1 (ru) * | 1995-10-17 | 1999-10-27 | Институт физиологически активных веществ РАН | Производные гидрированных пиридо(4,3-b)индолов, способы их получения, фармацевтическая композиция и способ лечения |
| RU2106864C1 (ru) * | 1995-10-23 | 1998-03-20 | Николай Серафимович Зефиров | Средство для лечения болезни альцгеймера |
| RU2283108C2 (ru) * | 2003-12-08 | 2006-09-10 | Сергей Олегович Бачурин | ГЕРОПРОТЕКТОР НА ОСНОВЕ ГИДРИРОВАННЫХ ПИРИДО(4,3-b) ИНДОЛОВ (ВАРИАНТЫ), ФАРМАКОЛОГИЧЕСКОЕ СРЕДСТВО НА ЕГО ОСНОВЕ И СПОСОБ ЕГО ПРИМЕНЕНИЯ |
| GB2422828A (en) * | 2005-02-03 | 2006-08-09 | Hunter Fleming Ltd | Tricyclic cytoprotective compounds comprising an indole residue |
-
2006
- 2006-12-07 RU RU2006143332/15A patent/RU2340342C2/ru not_active IP Right Cessation
-
2007
- 2007-11-30 WO PCT/US2007/024626 patent/WO2008073231A1/en not_active Ceased
- 2007-11-30 JP JP2009540237A patent/JP2010511701A/ja active Pending
- 2007-11-30 US US12/518,090 patent/US20110112132A1/en not_active Abandoned
- 2007-11-30 CA CA002671569A patent/CA2671569A1/en not_active Abandoned
- 2007-11-30 EP EP07867589A patent/EP2101578A4/en not_active Withdrawn
- 2007-11-30 AU AU2007332878A patent/AU2007332878A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| RU2340342C2 (ru) | 2008-12-10 |
| WO2008073231A1 (en) | 2008-06-19 |
| EP2101578A1 (en) | 2009-09-23 |
| EP2101578A4 (en) | 2012-09-05 |
| RU2006143332A (ru) | 2008-06-20 |
| JP2010511701A (ja) | 2010-04-15 |
| AU2007332878A1 (en) | 2008-06-19 |
| US20110112132A1 (en) | 2011-05-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| EEER | Examination request |
Effective date: 20121129 |
|
| FZDE | Discontinued |
Effective date: 20150515 |