CA2669217C - Mutant .delta.8 desaturase genes engineered by targeted mutagenesis and their use in making polyunsaturated fatty acids - Google Patents
Mutant .delta.8 desaturase genes engineered by targeted mutagenesis and their use in making polyunsaturated fatty acids Download PDFInfo
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- CA2669217C CA2669217C CA2669217A CA2669217A CA2669217C CA 2669217 C CA2669217 C CA 2669217C CA 2669217 A CA2669217 A CA 2669217A CA 2669217 A CA2669217 A CA 2669217A CA 2669217 C CA2669217 C CA 2669217C
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
- C12N9/0083—Miscellaneous (1.14.99)
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- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
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- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
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| US11/635,258 | 2006-12-07 | ||
| PCT/US2007/025001 WO2008073271A1 (en) | 2006-12-07 | 2007-12-05 | Mutant delta8 desaturase genes engineered by targeted mutagenesis and their use in making polyunsaturated fatty acids |
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| CA2669217C true CA2669217C (en) | 2015-07-14 |
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| US7790156B2 (en) * | 2007-04-10 | 2010-09-07 | E. I. Du Pont De Nemours And Company | Δ-8 desaturases and their use in making polyunsaturated fatty acids |
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| CN102595917A (zh) | 2009-06-16 | 2012-07-18 | 纳幕尔杜邦公司 | 来自改善的优化的解脂耶氏酵母菌株的高二十碳五烯酸油 |
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| CA2805882A1 (en) | 2010-08-11 | 2012-02-16 | E. I. Dupont De Nemours And Company | Improved aquaculture meat products |
| KR20140008295A (ko) | 2010-08-26 | 2014-01-21 | 이 아이 듀폰 디 네모아 앤드 캄파니 | 돌연변이 델타-9 연장효소 및 다중불포화 지방산의 제조에서의 그들의 용도 |
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| AU2011293180B2 (en) | 2010-08-26 | 2017-03-02 | E. I. Du Pont De Nemours And Company | Recombinant microbial host cells for high eicosapentaenoic acid production |
| MX2013004944A (es) * | 2010-11-05 | 2013-06-28 | Basf Plant Science Co Gmbh | Metodo para aumentar el rendimiento y la produccion de quimicos finos en las plantas. |
| US8735137B2 (en) | 2010-12-30 | 2014-05-27 | E I Du Pont De Nemours And Company | Use of Saccharomyces cerevisiae SUC2 gene in Yarrowia lipolytica for sucrose utilization |
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| US8816111B2 (en) | 2012-06-15 | 2014-08-26 | Commonwealth Scientific And Industrial Research Organisation | Lipid comprising polyunsaturated fatty acids |
| EP2935591B1 (en) | 2012-12-21 | 2017-07-05 | E. I. du Pont de Nemours and Company | Down-regulation of a polynucleotide encoding a sou2 sorbitol utilization protein to modify lipid production in microbial cells |
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| CN104293769B (zh) * | 2014-10-27 | 2016-06-01 | 徐毅 | 一种来源于绿色巴夫藻的delta8去饱和酶新基因 |
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| US7198937B2 (en) * | 2004-11-04 | 2007-04-03 | E. I. Du Pont De Nemours And Company | Mortierella alpina diacylglycerol acyltransferase for alteration of polyunsaturated fatty acids and oil content in oleaginous organisms |
| US8685679B2 (en) * | 2004-11-04 | 2014-04-01 | E I Du Pont De Nemours And Company | Acyltransferase regulation to increase the percent of polyunsaturated fatty acids in total lipids and oils of oleaginous organisms |
| US7470532B2 (en) * | 2005-10-19 | 2008-12-30 | E.I. Du Pont De Nemours And Company | Mortierella alpina C16/18 fatty acid elongase |
| AU2006316610B2 (en) * | 2005-11-23 | 2012-06-14 | E. I. Du Pont De Nemours And Company | Delta-9 elongases and their use in making polyunsaturated fatty acids |
| US7465793B2 (en) * | 2006-04-20 | 2008-12-16 | E.I. Du Pont De Nemours And Company | Synthetic Δ17 desaturase derived from Phytophthora ramourum and its use in making polyunsaturated fatty acids |
| US7943823B2 (en) | 2006-04-28 | 2011-05-17 | E.I. Du Pont De Nemours And Company | Delta-8 desaturase and its use in making polyunsaturated fatty acids |
| EP2013335A2 (en) * | 2006-05-01 | 2009-01-14 | E.I. Du Pont De Nemours And Company | Fungal delta12 desaturase and delta15 desaturase motifs |
| US7678560B2 (en) * | 2006-05-17 | 2010-03-16 | E.I. Du Pont De Nemours And Company | Δ 5 desaturase and its use in making polyunsaturated fatty acids |
| US7695950B2 (en) * | 2006-05-17 | 2010-04-13 | E. I. Du Pont De Nemours And Company | Δ5 desaturase and its use in making polyunsaturated fatty acids |
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2006
- 2006-12-07 US US11/635,258 patent/US7709239B2/en not_active Expired - Fee Related
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2007
- 2007-12-05 CA CA2669217A patent/CA2669217C/en not_active Expired - Fee Related
- 2007-12-05 EP EP07862593.6A patent/EP2087106B1/en not_active Not-in-force
- 2007-12-05 DK DK07862593.6T patent/DK2087106T3/en active
- 2007-12-05 WO PCT/US2007/025001 patent/WO2008073271A1/en not_active Ceased
- 2007-12-05 AU AU2007332918A patent/AU2007332918B2/en not_active Ceased
- 2007-12-05 CN CN2007800452327A patent/CN101627118B/zh not_active Expired - Fee Related
- 2007-12-05 JP JP2009540294A patent/JP5769374B2/ja not_active Expired - Fee Related
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2010
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Also Published As
| Publication number | Publication date |
|---|---|
| US20080138868A1 (en) | 2008-06-12 |
| JP5769374B2 (ja) | 2015-08-26 |
| WO2008073271A1 (en) | 2008-06-19 |
| CA2669217A1 (en) | 2008-06-19 |
| US7709239B2 (en) | 2010-05-04 |
| EP2087106B1 (en) | 2015-03-04 |
| AU2007332918A1 (en) | 2008-06-19 |
| AU2007332918B2 (en) | 2013-02-07 |
| JP2010512146A (ja) | 2010-04-22 |
| WO2008073271A9 (en) | 2009-04-30 |
| US20100297713A1 (en) | 2010-11-25 |
| DK2087106T3 (en) | 2015-06-08 |
| US8026089B2 (en) | 2011-09-27 |
| CN101627118B (zh) | 2013-07-17 |
| CN101627118A (zh) | 2010-01-13 |
| EP2087106A1 (en) | 2009-08-12 |
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