CA2661599C - Fusion proteins comprising tnf and fibritin trimerization domain - Google Patents
Fusion proteins comprising tnf and fibritin trimerization domain Download PDFInfo
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- CA2661599C CA2661599C CA2661599A CA2661599A CA2661599C CA 2661599 C CA2661599 C CA 2661599C CA 2661599 A CA2661599 A CA 2661599A CA 2661599 A CA2661599 A CA 2661599A CA 2661599 C CA2661599 C CA 2661599C
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70575—NGF/TNF-superfamily, e.g. CD70, CD95L, CD153, CD154
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
- C07K2319/73—Fusion polypeptide containing domain for protein-protein interaction containing coiled-coiled motif (leucine zippers)
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Toxicology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Cell Biology (AREA)
- Rheumatology (AREA)
- Diabetes (AREA)
- Hospice & Palliative Care (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Transplantation (AREA)
- Communicable Diseases (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Oncology (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CA2860945A CA2860945C (en) | 2006-08-28 | 2007-08-28 | Fusion proteins comprising trail and fibritin trimerization domain |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP06017891.0 | 2006-08-28 | ||
| EP06017891A EP1894940A1 (en) | 2006-08-28 | 2006-08-28 | TNF superfamily fusion proteins |
| PCT/EP2007/007517 WO2008025516A2 (en) | 2006-08-28 | 2007-08-28 | Tnf superfamily fusion proteins |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2860945A Division CA2860945C (en) | 2006-08-28 | 2007-08-28 | Fusion proteins comprising trail and fibritin trimerization domain |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2661599A1 CA2661599A1 (en) | 2008-03-06 |
| CA2661599C true CA2661599C (en) | 2015-06-09 |
Family
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Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
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| CA2661599A Expired - Fee Related CA2661599C (en) | 2006-08-28 | 2007-08-28 | Fusion proteins comprising tnf and fibritin trimerization domain |
| CA2860945A Expired - Fee Related CA2860945C (en) | 2006-08-28 | 2007-08-28 | Fusion proteins comprising trail and fibritin trimerization domain |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2860945A Expired - Fee Related CA2860945C (en) | 2006-08-28 | 2007-08-28 | Fusion proteins comprising trail and fibritin trimerization domain |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US8147843B2 (enExample) |
| EP (2) | EP1894940A1 (enExample) |
| JP (1) | JP5274464B2 (enExample) |
| AT (1) | ATE505481T1 (enExample) |
| AU (1) | AU2007291490A1 (enExample) |
| CA (2) | CA2661599C (enExample) |
| DE (1) | DE602007013920D1 (enExample) |
| WO (1) | WO2008025516A2 (enExample) |
Families Citing this family (71)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2657801T3 (es) | 2007-07-10 | 2018-03-06 | Apogenix Ag | Proteínas de fusión de colectina de la superfamilia de TNF |
| ES2524553T3 (es) * | 2008-06-17 | 2014-12-10 | Apogenix Gmbh | Receptores multiméricos de TNF |
| US20110189194A1 (en) * | 2008-07-14 | 2011-08-04 | Deutsches Krebsforschungszentrum Stiftung Des Offentlichen Rechts | Use of cd95 inhibitors for the treatment of inflammatory disorders |
| EP3103875A1 (en) * | 2008-07-21 | 2016-12-14 | Apogenix AG | Tnfsf single chain molecules |
| ES2593049T3 (es) | 2009-01-09 | 2016-12-05 | Apogenix Ag | Proteínas de fusión que forman trímeros |
| TWI476001B (zh) | 2011-12-26 | 2015-03-11 | Ind Tech Res Inst | 三倍體Ｆｃ融合蛋白及其用途 |
| AU2013295647B2 (en) | 2012-07-26 | 2018-02-08 | The Henry M. Jackson Foundation For The Advancement Of Military Medicine, Inc. | Multimeric fusion protein vaccine and immunotherapeutic |
| WO2014100913A1 (en) * | 2012-12-24 | 2014-07-03 | Beijing Anxinhuaide Biotech. Co., Ltd | Improving the half life of a therapeutic polypeptide by fusing with a trimeric scaffold protein via a spacer |
| NO2776305T3 (enExample) | 2014-04-23 | 2018-01-27 | ||
| BR102014031185A8 (pt) * | 2014-12-12 | 2021-05-04 | Fund De Amparo A Pesquisa Do Estado De Sao Paulo Fapesp | proteína recombinante indutora da apoptose; processo de obtenção da dita proteína e o seu uso no tratamento do câncer |
| JP7179464B2 (ja) | 2015-01-20 | 2022-11-29 | アイジーエム バイオサイエンシズ インコーポレイテッド | 腫瘍壊死因子 （ｔｎｆ） スーパーファミリー受容体結合分子およびその使用 |
| MA41460A (fr) | 2015-02-03 | 2017-12-12 | Oncomed Pharm Inc | Agents de liaison à la tnfrsf et leurs utilisations |
| EP3076179A1 (en) | 2015-03-30 | 2016-10-05 | Deutsches Krebsforschungszentrum Stiftung des Öffentlichen Rechts | Diagnosis and treatment of low grade gliomas |
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| WO2019103857A1 (en) | 2017-11-22 | 2019-05-31 | Iovance Biotherapeutics, Inc. | Expansion of peripheral blood lymphocytes (pbls) from peripheral blood |
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| KR102956273B1 (ko) | 2018-01-08 | 2026-04-24 | 이오반스 바이오테라퓨틱스, 인크. | 종양 항원-특이적 t-세포에 대해 풍부화된 til 생성물의 생성 방법 |
| US11713446B2 (en) | 2018-01-08 | 2023-08-01 | Iovance Biotherapeutics, Inc. | Processes for generating TIL products enriched for tumor antigen-specific T-cells |
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| EP1365027A4 (en) * | 2000-05-26 | 2005-06-22 | Mochida Pharm Co Ltd | FUSION PROTEINS AS FAS-LIGAND |
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2006
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- 2007-08-28 AU AU2007291490A patent/AU2007291490A1/en not_active Abandoned
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- 2007-08-28 EP EP07801940A patent/EP2069392B1/en not_active Not-in-force
- 2007-08-28 CA CA2661599A patent/CA2661599C/en not_active Expired - Fee Related
- 2007-08-28 WO PCT/EP2007/007517 patent/WO2008025516A2/en not_active Ceased
- 2007-08-28 JP JP2009525967A patent/JP5274464B2/ja not_active Expired - Fee Related
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2012
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Also Published As
| Publication number | Publication date |
|---|---|
| ATE505481T1 (de) | 2011-04-15 |
| JP2010501191A (ja) | 2010-01-21 |
| EP2069392B1 (en) | 2011-04-13 |
| AU2007291490A1 (en) | 2008-03-06 |
| US8580273B2 (en) | 2013-11-12 |
| CA2661599A1 (en) | 2008-03-06 |
| US20110027218A1 (en) | 2011-02-03 |
| EP2069392A2 (en) | 2009-06-17 |
| EP1894940A1 (en) | 2008-03-05 |
| CA2860945C (en) | 2015-12-29 |
| JP5274464B2 (ja) | 2013-08-28 |
| DE602007013920D1 (de) | 2011-05-26 |
| WO2008025516A3 (en) | 2008-04-17 |
| US8147843B2 (en) | 2012-04-03 |
| WO2008025516A2 (en) | 2008-03-06 |
| CA2860945A1 (en) | 2008-03-06 |
| US20120148527A1 (en) | 2012-06-14 |
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