CA2656620C - Cd20 binding molecules for the treatment of copd - Google Patents

Cd20 binding molecules for the treatment of copd Download PDF

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Publication number
CA2656620C
CA2656620C CA2656620A CA2656620A CA2656620C CA 2656620 C CA2656620 C CA 2656620C CA 2656620 A CA2656620 A CA 2656620A CA 2656620 A CA2656620 A CA 2656620A CA 2656620 C CA2656620 C CA 2656620C
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CA
Canada
Prior art keywords
antibody
human
mutant
use according
seq
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Active
Application number
CA2656620A
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English (en)
French (fr)
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CA2656620A1 (en
Inventor
Paul Parren
Steen Lisby
Ole Baadsgaard
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Genmab AS
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Genmab AS
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Publication of CA2656620A1 publication Critical patent/CA2656620A1/en
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Publication of CA2656620C publication Critical patent/CA2656620C/en
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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2887—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against CD20
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Pain & Pain Management (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CA2656620A 2006-07-04 2007-07-04 Cd20 binding molecules for the treatment of copd Active CA2656620C (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
DKPA200600916 2006-07-04
DKPA200600916 2006-07-04
US81859306P 2006-07-05 2006-07-05
US60/818,593 2006-07-05
PCT/DK2007/000339 WO2008003319A1 (en) 2006-07-04 2007-07-04 Cd20 binding molecules for the treatment of copd

Publications (2)

Publication Number Publication Date
CA2656620A1 CA2656620A1 (en) 2008-01-10
CA2656620C true CA2656620C (en) 2018-03-13

Family

ID=47390906

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2656620A Active CA2656620C (en) 2006-07-04 2007-07-04 Cd20 binding molecules for the treatment of copd

Country Status (5)

Country Link
US (1) US20130004480A1 (enExample)
EP (1) EP2046383B1 (enExample)
JP (2) JP5605895B2 (enExample)
CA (1) CA2656620C (enExample)
WO (1) WO2008003319A1 (enExample)

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US10501512B2 (en) 2012-04-02 2019-12-10 Modernatx, Inc. Modified polynucleotides
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WO2016168565A1 (en) * 2015-04-16 2016-10-20 President And Fellows Of Harvard College Methods for treatment of chronic obstructive pulmonary disease and/or therapy monitoring
US20180096104A1 (en) * 2016-10-05 2018-04-05 MED Inc. Disease management system
CA3045944A1 (en) 2016-12-07 2018-06-14 Progenity, Inc. Gastrointestinal tract detection methods, devices and systems
CN108395482B (zh) 2017-02-08 2021-02-05 西比曼生物科技（香港）有限公司 一种靶向cd20抗原嵌合抗原受体的构建及其工程化t细胞的活性鉴定
CA3054632A1 (en) 2017-03-30 2018-10-04 Progenity, Inc. Treatment of a disease of the gastrointestinal tract with an immune modulatory agent released using an ingestible device
US12227565B2 (en) 2018-06-20 2025-02-18 Biora Therapeutics, Inc. Method of formulating a pharmaceutical composition comprising administering an immune modulator to the small intestine
US20230041197A1 (en) 2018-06-20 2023-02-09 Progenity, Inc. Treatment of a disease of the gastrointestinal tract with an immunomodulator
CN113348011B (zh) 2018-11-19 2023-04-18 比奥拉治疗股份有限公司 用生物治疗剂治疗疾病的方法和装置
CN121197633A (zh) 2019-12-13 2025-12-26 比特比德科有限责任公司 用于将治疗剂递送至胃肠道的可摄取装置
CN113402612A (zh) 2020-03-17 2021-09-17 西比曼生物科技（香港）有限公司 靶向cd19和cd20的联合嵌合抗原受体及其应用
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Also Published As

Publication number Publication date
EP2046383B1 (en) 2014-11-19
JP2014208651A (ja) 2014-11-06
JP2009541374A (ja) 2009-11-26
JP5605895B2 (ja) 2014-10-15
EP2046383A1 (en) 2009-04-15
US20130004480A1 (en) 2013-01-03
WO2008003319A1 (en) 2008-01-10
CA2656620A1 (en) 2008-01-10

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