CA2656034A1 - Fused [d]pyridazin-7-ones - Google Patents
Fused [d]pyridazin-7-ones Download PDFInfo
- Publication number
- CA2656034A1 CA2656034A1 CA002656034A CA2656034A CA2656034A1 CA 2656034 A1 CA2656034 A1 CA 2656034A1 CA 002656034 A CA002656034 A CA 002656034A CA 2656034 A CA2656034 A CA 2656034A CA 2656034 A1 CA2656034 A1 CA 2656034A1
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- Prior art keywords
- hydrogen
- groups
- compound
- substituted
- alkyl
- Prior art date
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- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
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- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
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- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
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- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
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- Engineering & Computer Science (AREA)
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- Ophthalmology & Optometry (AREA)
- Hospice & Palliative Care (AREA)
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US81571706P | 2006-06-22 | 2006-06-22 | |
| US60/815,717 | 2006-06-22 | ||
| US11/820,887 | 2007-06-21 | ||
| US11/820,887 US7732447B2 (en) | 2006-06-22 | 2007-06-21 | Fused [d]pyridazin-7-ones |
| PCT/US2007/014559 WO2007149557A1 (en) | 2006-06-22 | 2007-06-22 | FUSED [d]PYRIDAZIN-7-ONES |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2656034A1 true CA2656034A1 (en) | 2007-12-27 |
Family
ID=38626544
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002656034A Abandoned CA2656034A1 (en) | 2006-06-22 | 2007-06-22 | Fused [d]pyridazin-7-ones |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US7732447B2 (https=) |
| EP (1) | EP2035429B1 (https=) |
| JP (1) | JP2010504277A (https=) |
| CN (1) | CN101501038B (https=) |
| AU (1) | AU2007261305B2 (https=) |
| CA (1) | CA2656034A1 (https=) |
| ES (1) | ES2393216T3 (https=) |
| IL (1) | IL196014A0 (https=) |
| MX (1) | MX2008016388A (https=) |
| NZ (1) | NZ573693A (https=) |
| WO (1) | WO2007149557A1 (https=) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2744498C (en) | 2008-11-25 | 2017-10-24 | University Of Rochester | Mlk inhibitors and methods of use |
| AU2011258465B2 (en) | 2010-05-24 | 2016-12-15 | University Of Rochester | Bicyclic heteroaryl kinase inhibitors and methods of use |
| EP2925319B1 (en) | 2012-11-30 | 2019-01-09 | University Of Rochester | Mixed lineage kinase inhibitors for hiv/aids therapies |
| UA115576C2 (uk) * | 2012-12-06 | 2017-11-27 | Байєр Фарма Акцієнгезелльшафт | Похідні бензимідазолу як антагоністи ер4 |
| KR102129842B1 (ko) * | 2013-10-02 | 2020-07-06 | 주식회사 대웅제약 | 술포닐인돌 유도체 및 이의 제조방법 |
| CN110573509B (zh) * | 2017-02-28 | 2023-05-26 | 北京生命科学研究所 | Mlkl抑制剂 |
| RU2019133646A (ru) * | 2017-03-30 | 2021-04-30 | Ф. Хоффманн-Ля Рош Аг | Изохинолины в качестве ингибиторов hpk1 |
| US11485734B2 (en) | 2018-10-02 | 2022-11-01 | Northwestern University | Beta-carbolines as positive allosteric modulators of the human serotonin receptor 2C (5-HT2C) |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
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| GB9109972D0 (en) * | 1991-05-09 | 1991-07-03 | Ici Plc | Therapeutic compounds |
| JP3553158B2 (ja) | 1994-10-14 | 2004-08-11 | ポーラ化成工業株式会社 | ピリダジノインドール誘導体 |
| EP1002535A1 (en) | 1998-10-28 | 2000-05-24 | Hrissanthi Ikonomidou | New use of glutamate antagonists for the treatment of cancer |
| GB0121941D0 (en) | 2001-09-11 | 2001-10-31 | Astrazeneca Ab | Chemical compounds |
| FR2833953B1 (fr) * | 2001-12-21 | 2004-12-03 | Sanofi Synthelabo | DERIVES DE 3-HETEROARYL-3,5-DIHYDRO-4-OXO-4H-PYRIDAZINO [4,5-b]INDOLE-1-CARBOXAMIDE, LEUR PREPARATION ET LEUR APPLICATION EN THERAPEUTIQUE |
| AU2003272175A1 (en) | 2002-10-21 | 2004-05-04 | Aprea Ab | Reactivation of wild type p53 in human tumour cells by a low molecular weight compound |
| FR2876377B1 (fr) | 2004-10-11 | 2007-03-16 | Univ Claude Bernard Lyon | Nouveaux derives de 9h-pyrido[2,3-b]indole, leur procede de preparation, ainsi que les compositions pharmaceutiques contenant de tels composes |
-
2007
- 2007-06-21 US US11/820,887 patent/US7732447B2/en not_active Expired - Fee Related
- 2007-06-22 CN CN2007800297073A patent/CN101501038B/zh not_active Expired - Fee Related
- 2007-06-22 NZ NZ573693A patent/NZ573693A/en not_active IP Right Cessation
- 2007-06-22 WO PCT/US2007/014559 patent/WO2007149557A1/en not_active Ceased
- 2007-06-22 ES ES07796360T patent/ES2393216T3/es active Active
- 2007-06-22 AU AU2007261305A patent/AU2007261305B2/en not_active Ceased
- 2007-06-22 MX MX2008016388A patent/MX2008016388A/es active IP Right Grant
- 2007-06-22 EP EP07796360A patent/EP2035429B1/en not_active Not-in-force
- 2007-06-22 JP JP2009516579A patent/JP2010504277A/ja not_active Ceased
- 2007-06-22 CA CA002656034A patent/CA2656034A1/en not_active Abandoned
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2008
- 2008-12-17 IL IL196014A patent/IL196014A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP2010504277A (ja) | 2010-02-12 |
| IL196014A0 (en) | 2009-09-01 |
| EP2035429B1 (en) | 2012-09-19 |
| AU2007261305B2 (en) | 2012-10-04 |
| EP2035429A1 (en) | 2009-03-18 |
| ES2393216T3 (es) | 2012-12-19 |
| HK1128467A1 (en) | 2009-10-30 |
| NZ573693A (en) | 2011-12-22 |
| AU2007261305A1 (en) | 2007-12-27 |
| CN101501038A (zh) | 2009-08-05 |
| WO2007149557A1 (en) | 2007-12-27 |
| MX2008016388A (es) | 2009-02-12 |
| US20070299061A1 (en) | 2007-12-27 |
| US7732447B2 (en) | 2010-06-08 |
| CN101501038B (zh) | 2012-07-18 |
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| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| FZDE | Discontinued |
Effective date: 20140625 |