AU2007261305B2 - Fused (d)pyridazin-7-ones - Google Patents
Fused (d)pyridazin-7-ones Download PDFInfo
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- AU2007261305B2 AU2007261305B2 AU2007261305A AU2007261305A AU2007261305B2 AU 2007261305 B2 AU2007261305 B2 AU 2007261305B2 AU 2007261305 A AU2007261305 A AU 2007261305A AU 2007261305 A AU2007261305 A AU 2007261305A AU 2007261305 B2 AU2007261305 B2 AU 2007261305B2
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- HRZFUMHJMZEROT-UHFFFAOYSA-L sodium disulfite Chemical compound [Na+].[Na+].[O-]S(=O)S([O-])(=O)=O HRZFUMHJMZEROT-UHFFFAOYSA-L 0.000 description 1
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- 239000000454 talc Substances 0.000 description 1
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- 125000000999 tert-butyl group Chemical group [H]C([H])([H])C(*)(C([H])([H])[H])C([H])([H])[H] 0.000 description 1
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- 125000003718 tetrahydrofuranyl group Chemical group 0.000 description 1
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- 125000001712 tetrahydronaphthyl group Chemical group C1(CCCC2=CC=CC=C12)* 0.000 description 1
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Classifications
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- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Neurology (AREA)
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- Neurosurgery (AREA)
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US81571706P | 2006-06-22 | 2006-06-22 | |
| US60/815,717 | 2006-06-22 | ||
| US11/820,887 | 2007-06-21 | ||
| US11/820,887 US7732447B2 (en) | 2006-06-22 | 2007-06-21 | Fused [d]pyridazin-7-ones |
| PCT/US2007/014559 WO2007149557A1 (en) | 2006-06-22 | 2007-06-22 | FUSED [d]PYRIDAZIN-7-ONES |
Publications (2)
| Publication Number | Publication Date |
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| AU2007261305A1 AU2007261305A1 (en) | 2007-12-27 |
| AU2007261305B2 true AU2007261305B2 (en) | 2012-10-04 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
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| AU2007261305A Ceased AU2007261305B2 (en) | 2006-06-22 | 2007-06-22 | Fused (d)pyridazin-7-ones |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US7732447B2 (https=) |
| EP (1) | EP2035429B1 (https=) |
| JP (1) | JP2010504277A (https=) |
| CN (1) | CN101501038B (https=) |
| AU (1) | AU2007261305B2 (https=) |
| CA (1) | CA2656034A1 (https=) |
| ES (1) | ES2393216T3 (https=) |
| IL (1) | IL196014A0 (https=) |
| MX (1) | MX2008016388A (https=) |
| NZ (1) | NZ573693A (https=) |
| WO (1) | WO2007149557A1 (https=) |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CA2744498C (en) | 2008-11-25 | 2017-10-24 | University Of Rochester | Mlk inhibitors and methods of use |
| AU2011258465B2 (en) | 2010-05-24 | 2016-12-15 | University Of Rochester | Bicyclic heteroaryl kinase inhibitors and methods of use |
| EP2925319B1 (en) | 2012-11-30 | 2019-01-09 | University Of Rochester | Mixed lineage kinase inhibitors for hiv/aids therapies |
| UA115576C2 (uk) * | 2012-12-06 | 2017-11-27 | Байєр Фарма Акцієнгезелльшафт | Похідні бензимідазолу як антагоністи ер4 |
| KR102129842B1 (ko) * | 2013-10-02 | 2020-07-06 | 주식회사 대웅제약 | 술포닐인돌 유도체 및 이의 제조방법 |
| CN110573509B (zh) * | 2017-02-28 | 2023-05-26 | 北京生命科学研究所 | Mlkl抑制剂 |
| RU2019133646A (ru) * | 2017-03-30 | 2021-04-30 | Ф. Хоффманн-Ля Рош Аг | Изохинолины в качестве ингибиторов hpk1 |
| US11485734B2 (en) | 2018-10-02 | 2022-11-01 | Northwestern University | Beta-carbolines as positive allosteric modulators of the human serotonin receptor 2C (5-HT2C) |
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| GB9109972D0 (en) * | 1991-05-09 | 1991-07-03 | Ici Plc | Therapeutic compounds |
| JP3553158B2 (ja) | 1994-10-14 | 2004-08-11 | ポーラ化成工業株式会社 | ピリダジノインドール誘導体 |
| EP1002535A1 (en) | 1998-10-28 | 2000-05-24 | Hrissanthi Ikonomidou | New use of glutamate antagonists for the treatment of cancer |
| GB0121941D0 (en) | 2001-09-11 | 2001-10-31 | Astrazeneca Ab | Chemical compounds |
| FR2833953B1 (fr) * | 2001-12-21 | 2004-12-03 | Sanofi Synthelabo | DERIVES DE 3-HETEROARYL-3,5-DIHYDRO-4-OXO-4H-PYRIDAZINO [4,5-b]INDOLE-1-CARBOXAMIDE, LEUR PREPARATION ET LEUR APPLICATION EN THERAPEUTIQUE |
| AU2003272175A1 (en) | 2002-10-21 | 2004-05-04 | Aprea Ab | Reactivation of wild type p53 in human tumour cells by a low molecular weight compound |
| FR2876377B1 (fr) | 2004-10-11 | 2007-03-16 | Univ Claude Bernard Lyon | Nouveaux derives de 9h-pyrido[2,3-b]indole, leur procede de preparation, ainsi que les compositions pharmaceutiques contenant de tels composes |
-
2007
- 2007-06-21 US US11/820,887 patent/US7732447B2/en not_active Expired - Fee Related
- 2007-06-22 CN CN2007800297073A patent/CN101501038B/zh not_active Expired - Fee Related
- 2007-06-22 NZ NZ573693A patent/NZ573693A/en not_active IP Right Cessation
- 2007-06-22 WO PCT/US2007/014559 patent/WO2007149557A1/en not_active Ceased
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- 2007-06-22 MX MX2008016388A patent/MX2008016388A/es active IP Right Grant
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- 2007-06-22 JP JP2009516579A patent/JP2010504277A/ja not_active Ceased
- 2007-06-22 CA CA002656034A patent/CA2656034A1/en not_active Abandoned
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2008
- 2008-12-17 IL IL196014A patent/IL196014A0/en unknown
Non-Patent Citations (1)
| Title |
|---|
| MONGE, A. et al., Journal of Heterocyclic Chemistry, 1984, vol. 21, pages 397-400 * |
Also Published As
| Publication number | Publication date |
|---|---|
| CA2656034A1 (en) | 2007-12-27 |
| JP2010504277A (ja) | 2010-02-12 |
| IL196014A0 (en) | 2009-09-01 |
| EP2035429B1 (en) | 2012-09-19 |
| EP2035429A1 (en) | 2009-03-18 |
| ES2393216T3 (es) | 2012-12-19 |
| HK1128467A1 (en) | 2009-10-30 |
| NZ573693A (en) | 2011-12-22 |
| AU2007261305A1 (en) | 2007-12-27 |
| CN101501038A (zh) | 2009-08-05 |
| WO2007149557A1 (en) | 2007-12-27 |
| MX2008016388A (es) | 2009-02-12 |
| US20070299061A1 (en) | 2007-12-27 |
| US7732447B2 (en) | 2010-06-08 |
| CN101501038B (zh) | 2012-07-18 |
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