CA2655168A1 - Medical devices and coatings with non-leaching antimicrobial peptides - Google Patents

Medical devices and coatings with non-leaching antimicrobial peptides Download PDF

Info

Publication number
CA2655168A1
CA2655168A1 CA002655168A CA2655168A CA2655168A1 CA 2655168 A1 CA2655168 A1 CA 2655168A1 CA 002655168 A CA002655168 A CA 002655168A CA 2655168 A CA2655168 A CA 2655168A CA 2655168 A1 CA2655168 A1 CA 2655168A1
Authority
CA
Canada
Prior art keywords
composition
substrate
peptide
peptides
antimicrobial
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002655168A
Other languages
English (en)
French (fr)
Inventor
Lino Ferreira
Robert S. Langer
Christopher R. Loose
William Shannan O'shaughnessy
Andreas Zumbuehl
Gregory Stephanopolous
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Massachusetts Institute of Technology
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US11/561,266 external-priority patent/US7739055B2/en
Application filed by Individual filed Critical Individual
Publication of CA2655168A1 publication Critical patent/CA2655168A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10—Peptides having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties
    • A61L15/46—Deodorants or malodour counteractants, e.g. to inhibit the formation of ammonia or bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Disinfection or sterilisation of materials or objects, in general; Accessories therefor
    • A61L2/16—Disinfection or sterilisation of materials or objects, in general; Accessories therefor using chemical substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Disinfection or sterilisation of materials or objects, in general; Accessories therefor
    • A61L2/16—Disinfection or sterilisation of materials or objects, in general; Accessories therefor using chemical substances
    • A61L2/23—Solid materials, e.g. granules, powders, blocks or tablets
    • A61L2/232—Solid materials, e.g. granules, powders, blocks or tablets layered or coated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/227—Other specific proteins or polypeptides not covered by A61L27/222, A61L27/225 or A61L27/24
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28—Materials for coating prostheses
    • A61L27/34—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/08—Materials for coatings
    • A61L29/085—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08—Materials for coatings
    • A61L31/10—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/25—Peptides having up to 20 amino acids in a defined sequence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/404—Biocides, antimicrobial agents, antiseptic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Vascular Medicine (AREA)
  • Surgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Materials Engineering (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
CA002655168A 2006-02-15 2007-02-15 Medical devices and coatings with non-leaching antimicrobial peptides Abandoned CA2655168A1 (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US77405006P 2006-02-15 2006-02-15
US60/774,050 2006-02-15
US11/561,266 US7739055B2 (en) 2005-11-17 2006-11-17 Methods and systems for generating and evaluating peptides
US11/561,266 2006-11-17
US88557807P 2007-01-18 2007-01-18
US60/885,578 2007-01-18
PCT/US2007/004394 WO2007095393A2 (en) 2006-02-15 2007-02-15 Medical devices and coatings with non-leaching antimicrobial peptides

Publications (1)

Publication Number Publication Date
CA2655168A1 true CA2655168A1 (en) 2007-08-23

Family

ID=38372168

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002655168A Abandoned CA2655168A1 (en) 2006-02-15 2007-02-15 Medical devices and coatings with non-leaching antimicrobial peptides

Country Status (5)

Country Link
US (1) US20070254006A1 (https=)
EP (1) EP1991245A2 (https=)
JP (1) JP2009526862A (https=)
CA (1) CA2655168A1 (https=)
WO (1) WO2007095393A2 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN118325376A (zh) * 2024-03-29 2024-07-12 泛领生物医学技术(苏州)有限公司 一种抗微生物涂层及其制备方法与应用

Families Citing this family (81)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060057180A1 (en) * 2004-02-20 2006-03-16 Ashutosh Chilkoti Tunable nonfouling surface of oligoethylene glycol
US7824691B2 (en) * 2005-04-04 2010-11-02 Centegen, Inc. Use of RIP in treating staphylococcus aureus infections
GB0624423D0 (en) * 2006-12-06 2007-01-17 Univ Brighton Biomaterials with Functionalised Surfaces
US20090149673A1 (en) * 2007-12-05 2009-06-11 Semprus Biosciences Corp. Synthetic non-fouling amino acids
US20090155335A1 (en) * 2007-12-05 2009-06-18 Semprus Biosciences Corp. Non-leaching non-fouling antimicrobial coatings
US8034396B2 (en) 2008-04-01 2011-10-11 Tyco Healthcare Group Lp Bioadhesive composition formed using click chemistry
WO2012068179A1 (en) * 2010-11-15 2012-05-24 Rutgers, The State University Of New Jersey Multifunctional biodegradable peg nanocarrier-based hydrogels for preventing hiv transmission
GB0808350D0 (en) * 2008-05-09 2008-06-18 Airbus Uk Ltd Self-cleaning surfaces
GB0818074D0 (en) * 2008-10-02 2008-11-05 Lytix Biopharma As Treatment of biofilms
DE102008053892A1 (de) * 2008-10-30 2010-05-06 Fachhochschule Gelsenkirchen Medizinisches Implantat mit biofunktionalisierter Oberfläche
NZ593201A (en) * 2008-12-05 2013-05-31 Semprus Biosciences Corp Non-fouling, anti-microbial, anti-thrombogenic graft-from compositions
EP2352796A1 (en) * 2008-12-05 2011-08-10 Semprus Biociences Corporation Layered non-fouling, antimicrobial, antithrombogenic coatings
MX2011007824A (es) 2009-02-03 2011-10-11 Chandrika Varadachari Fertilizantes de micronutrientes y metodos de elaboracion y uso de los mismos.
US8877170B2 (en) 2009-02-21 2014-11-04 Sofradim Production Medical device with inflammatory response-reducing coating
US8968733B2 (en) 2009-02-21 2015-03-03 Sofradim Production Functionalized surgical adhesives
EP2398519A2 (en) 2009-02-21 2011-12-28 Sofradim Production Compounds and medical devices activated with solvophobic linkers
CA2753188A1 (en) 2009-02-21 2010-08-26 Tyco Healthcare Group Lp Medical devices having activated surfaces
US8535477B2 (en) 2009-02-21 2013-09-17 Sofradim Production Medical devices incorporating functional adhesives
WO2010095049A1 (en) 2009-02-21 2010-08-26 Sofradim Production Crosslinked fibers and method of making same by extrusion
US9523159B2 (en) 2009-02-21 2016-12-20 Covidien Lp Crosslinked fibers and method of making same using UV radiation
US9039979B2 (en) 2009-02-21 2015-05-26 Sofradim Production Apparatus and method of reacting polymers passing through metal ion chelated resin matrix to produce injectable medical devices
EP2398584A2 (en) 2009-02-21 2011-12-28 Sofradim Production Apparatus and method of reaching polymers by exposure to uv radiation to produce injectable medical devices
US8512728B2 (en) 2009-02-21 2013-08-20 Sofradim Production Method of forming a medical device on biological tissue
EP2398524B1 (en) 2009-02-21 2017-07-12 Covidien LP Medical devices having activated surfaces
US8663689B2 (en) 2009-02-21 2014-03-04 Sofradim Production Functionalized adhesive medical gel
WO2010095045A1 (en) 2009-02-21 2010-08-26 Sofradim Production Amphiphilic compounds and self-assembling compositions made therefrom
WO2010095056A2 (en) 2009-02-21 2010-08-26 Sofradim Production Medical devices with an activated coating
US9181137B2 (en) 2009-03-20 2015-11-10 Agtec Innovations, Inc. Micronutrient fertilizers and methods of making and using the same
US8505743B2 (en) * 2009-04-08 2013-08-13 Michigan Molecular Institute Surface modification of polyamide reverse osmosis membranes
EP2509614A4 (en) * 2009-12-07 2014-08-06 Univ Ben Gurion ANTIMICROBIAL WATER TREATMENT MEMBRANES AND MANUFACTURE THEREOF
AU2011231245B2 (en) 2010-03-25 2015-03-26 Covidien Lp Medical devices incorporating functional adhesives
CA2794336A1 (en) 2010-03-25 2011-09-29 Sofradim Production Surgical fasteners and methods for sealing wounds
WO2011127463A1 (en) 2010-04-09 2011-10-13 Brown University Nanostructured surfaces
EP2579908A4 (en) * 2010-06-09 2016-03-23 Arrow Int Inc ANTITHROMBOGENIC, ANTIMICROBIAL AND ANTIFOULING COMPOSITIONS WITH GRAFT FORM
CA2799641C (en) 2010-06-09 2016-08-30 Semprus Biosciences Corp. Articles having non-fouling surfaces and processes for preparing the same including applying a primer coat
CA2799786A1 (en) 2010-06-09 2011-12-15 Semprus Biosciences Corp. Non-fouling, anti-microbial, anti-thrombogenic graft compositions
CA2804263A1 (en) 2010-06-29 2012-01-12 Tyco Healthcare Group Lp Microwave-powered reactor and method for in situ forming implants
WO2012006000A1 (en) * 2010-06-29 2012-01-12 Waters Technologies Corporation Antimicrobial layer for chromatographic systems
EP2588153A2 (en) 2010-07-01 2013-05-08 Sofradim Production Medical device with predefined activated cellular integration
EP2598178B1 (en) 2010-07-27 2018-07-11 Sofradim Production Polymeric fibers having tissue reactive members
EP2603472B1 (en) 2010-08-10 2019-03-27 Agtec Innovations, Inc. Phosphate fertilizers and methods of using the same
AU2011288133B2 (en) 2010-08-10 2014-02-27 Agtec Innovations, Inc. Polyphosphate fertilizer combinations
CN102462859A (zh) * 2010-11-18 2012-05-23 私立中原大学 皮肤伤口愈合材料及其制造方法
HK1199201A1 (en) * 2011-10-10 2015-06-26 BERECZ, Roland Antimicrobial peptides for treatment of infectious diseases
EP2791211A4 (en) 2011-12-14 2015-08-05 Semprus Biosciences Corp MULTI-STAGE UV PROCESS FOR CREATING CONTACT LENSES WITH MODIFIED SURFACE
EP2791214A4 (en) 2011-12-14 2015-11-04 Semprus Biosciences Corp REDOX PROCESS FOR CONTACT LENS MODIFICATION
MX2014007211A (es) 2011-12-14 2015-04-14 Semprus Biosciences Corp Lente de contacto de hidrogel de silicona modificada usando oxidantes de lantanido o de metal de transicion.
MX2014007203A (es) 2011-12-14 2015-04-14 Semprus Biosciences Corp Proceso de imbibicion para modificacion de superficie de lente de contacto.
US9004682B2 (en) 2011-12-14 2015-04-14 Semprus Biosciences Corporation Surface modified contact lenses
US8545951B2 (en) * 2012-02-29 2013-10-01 Kimberly-Clark Worldwide, Inc. Endotracheal tubes and other polymer substrates including an anti-fouling treatment
ES2863023T3 (es) * 2012-09-12 2021-10-08 Biocant Centro De Inovacao Em Biotecnologia Composiciones de recubrimiento antimicrobianas
JP6502861B2 (ja) 2013-02-21 2019-04-17 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 汎用拡張性高費用効率表面修飾
US9149036B1 (en) * 2013-06-06 2015-10-06 Lloyd Starks Method for applying a persistent antimicrobial film
US9775928B2 (en) 2013-06-18 2017-10-03 Covidien Lp Adhesive barbed filament
FR3016128B1 (fr) * 2014-01-07 2018-03-23 Aptar France Sas Tete de distribution et d'application.
CN104189963B (zh) * 2014-05-13 2017-01-04 江苏沣沅医疗器械有限公司 降低可全降解镁合金血管支架降解速率的表面涂层制备方法
CN107635589B (zh) * 2015-03-06 2020-07-17 约翰·保罗·威尔逊 本质上抗微生物剂多孔基质复合物和制造其的方法
US10071133B2 (en) 2015-03-12 2018-09-11 Mitsui Chemicals, Inc. Method for destroying exosomes, kit for destroying exosomes, and method for isolating exosomes derived from normal cells
KR101693749B1 (ko) 2015-04-06 2017-01-06 삼성전기주식회사 인덕터 소자 및 그 제조방법
WO2016196633A1 (en) * 2015-06-01 2016-12-08 William Marsh Rice University Surface coating method to improve implantable device biocompatibility
GB201512031D0 (en) * 2015-07-09 2015-08-19 Univ Birmingham Functionalized surface
KR101659697B1 (ko) * 2015-10-02 2016-09-23 경희대학교 산학협력단 의료용 임플란트 및 그의 제조방법
KR101732490B1 (ko) * 2016-01-07 2017-05-04 숙명여자대학교산학협력단 기상 분자층 증착법을 이용하여 제조된 외부자극에 의해 분해가 가능한 고분자 구조체 및 그 제조방법
US10629880B2 (en) 2016-12-01 2020-04-21 The Regents Of The University Of California Energy providing devices and applications thereof
SE541313C2 (en) * 2017-10-13 2019-06-25 Amferia Ab Amphiphilic antimicrobial hydrogel
KR102762180B1 (ko) 2017-12-01 2025-02-05 더 리전트 오브 더 유니버시티 오브 캘리포니아 바이오파울링 저항성 코팅 및 이의 제조 및 사용 방법
EP3610728A1 (en) * 2018-08-14 2020-02-19 EMPA Eidgenössische Materialprüfungs- und Forschungsanstalt Antimicrobial coatings
CN111686312B (zh) * 2019-03-12 2022-07-15 华东理工大学 一种医用材料表面抗菌修饰层的制备方法及应用
WO2020214836A1 (en) 2019-04-16 2020-10-22 Academia Sinica Methods of coating antimicrobial peptides on the biomaterial and the biomaterial coated thereby
WO2020247629A1 (en) 2019-06-05 2020-12-10 The Regents Of The University Of California Biofouling resistant coatings and methods of making and using the same
US12016802B2 (en) 2019-10-22 2024-06-25 Aerobiotix. Llc Air treatment system for operating or patient rooms
CN110841107A (zh) * 2019-12-12 2020-02-28 中国科学院深圳先进技术研究院 植入性材料、制备方法、植入性医疗器械及组织工程支架
US20230076173A1 (en) * 2020-02-09 2023-03-09 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Antimicrobial matrix and uses thereof for eliminating microorganisms
CN111995788B (zh) * 2020-04-26 2021-09-21 中国科学院长春应用化学研究所 一种具有细菌响应性的聚合物刷及其制备方法
GB202008978D0 (en) * 2020-06-12 2020-07-29 Amicoat As Antimicrobial formulation
GB202008980D0 (en) * 2020-06-12 2020-07-29 Amicoat As Medical devices and materials
CN112870434B (zh) * 2021-01-22 2023-03-24 江苏大学 一种杀菌/抑菌生物活性界面材料及其制备方法
CN114432489A (zh) * 2022-01-29 2022-05-06 阳光生物科技有限公司 在金属表面制备具有长效抗菌效果多肽涂层的方法
CN114949374B (zh) * 2022-05-24 2023-06-13 安徽大学 一种抗菌促成骨双功能钛金属骨科植入物及其制备方法
CN116617470A (zh) * 2023-06-01 2023-08-22 四川大学 一种用于治疗植入物细菌感染的抗菌涂层及方法
WO2025129192A1 (en) * 2023-12-15 2025-06-19 Cascade Biocatalysts, Inc Polymer brush compositions including chain-end-immobilized cofactors and methods for the production thereof

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US329344A (en) * 1885-10-27 Geobge d
US329360A (en) * 1885-10-27 Automatic fire-extinguisher
US4098728A (en) * 1976-01-02 1978-07-04 Solomon Rosenblatt Medical surgical sponge and method of making same
US4211227A (en) * 1978-07-03 1980-07-08 The Kendall Company Surgical sponge material
US4254107A (en) * 1979-11-27 1981-03-03 Merck & Co., Inc. Long-lasting agonists of enkephalin
US5258041A (en) * 1982-09-29 1993-11-02 Bio-Metric Systems, Inc. Method of biomolecule attachment to hydrophobic surfaces
US4534881A (en) * 1983-12-19 1985-08-13 University Of South Alabama Inhibition of inorganic or biological CaCO3 deposition by poly amino acid derivatives
US4636208A (en) * 1984-10-05 1987-01-13 Ewald Rath Surgical sponge
LU86987A1 (fr) * 1987-09-07 1989-04-06 Glaverbel Microbilles de verre a proprietes bacteriostatiques,procede de fabrication de telles microbilles
US5585353A (en) * 1990-02-02 1996-12-17 The Rockefeller University Antibiotic peptides containing D-amino acids
US5180375A (en) * 1991-05-02 1993-01-19 Feibus Miriam H Woven surgical drain and woven surgical sponge
US6441130B1 (en) * 1991-05-24 2002-08-27 Isis Pharmaceuticals, Inc. Linked peptide nucleic acids
US5847047A (en) * 1993-06-22 1998-12-08 E. I. Du Pont De Nemours And Company Antimicrobial composition of a polymer and a peptide forming amphiphilic helices of the magainin-type
US5811151A (en) * 1996-05-31 1998-09-22 Medtronic, Inc. Method of modifying the surface of a medical device
FR2751882B1 (fr) * 1996-07-31 1998-10-02 Inst Curie Surfaces hyperbactericides
US6054504A (en) * 1997-12-31 2000-04-25 Hydromer, Inc. Biostatic coatings for the reduction and prevention of bacterial adhesion
US6140127A (en) * 1998-02-18 2000-10-31 Cordis Corporation Method of coating an intravascular stent with an endothelial cell adhesive five amino acid peptide
ATE275977T1 (de) * 1998-04-13 2004-10-15 Massachusetts Inst Technology Kamm-polymere zur regelung der zelloberflächenwechselwirkung
DE19841585A1 (de) * 1998-09-11 2000-03-16 Rheinmetall W & M Gmbh Waffenrohr mit einer im Bereich der Rohrmündung angeordneten Kollimatorhalterung
US6592814B2 (en) * 1998-10-02 2003-07-15 Johnson & Johnson Vision Care, Inc. Biomedical devices with antimicrobial coatings
WO2000063079A1 (en) * 1999-04-15 2000-10-26 Ultracell Medical Technologies Of Connecticut, Inc. Method for producing surgical sponge device and product thereof
ATE262856T1 (de) * 1999-06-24 2004-04-15 Abbott Vascular Devices Ltd Mittels eines ballons expandierbarer stent
JP2004513981A (ja) * 2000-07-17 2004-05-13 プレジデント・アンド・フェローズ・オブ・ハーバード・カレッジ 生物種の吸着に耐える表面
US6844028B2 (en) * 2001-06-26 2005-01-18 Accelr8 Technology Corporation Functional surface coating
US8172395B2 (en) * 2002-12-03 2012-05-08 Novartis Ag Medical devices having antimicrobial coatings thereon
US7282214B2 (en) * 2002-12-19 2007-10-16 Johnson & Johnson Vision Care, Inc. Biomedical devices with antimicrobial coatings
WO2005019241A2 (en) * 2003-08-18 2005-03-03 E.I. Dupont De Nemours And Company Cationic antimicrobial peptides and compositions thereof
US7603239B2 (en) * 2004-05-05 2009-10-13 Massachusetts Institute Of Technology Methods and systems for generating peptides
US20070048249A1 (en) * 2005-08-24 2007-03-01 Purdue Research Foundation Hydrophilized bactericidal polymers
WO2007061850A2 (en) * 2005-11-17 2007-05-31 Massachusetts Institute Of Technology Methods and systems for generating and evaluating peptides

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN118325376A (zh) * 2024-03-29 2024-07-12 泛领生物医学技术(苏州)有限公司 一种抗微生物涂层及其制备方法与应用

Also Published As

Publication number Publication date
US20070254006A1 (en) 2007-11-01
WO2007095393A2 (en) 2007-08-23
EP1991245A2 (en) 2008-11-19
WO2007095393A3 (en) 2008-09-25
JP2009526862A (ja) 2009-07-23
WO2007095393A9 (en) 2011-01-20

Similar Documents

Publication Publication Date Title
US20070254006A1 (en) Medical Devices and Coatings with Non-Leaching Antimicrobial Peptides
US20090155335A1 (en) Non-leaching non-fouling antimicrobial coatings
WO2009075788A1 (en) Synthetic non-fouling amino acids
Yan et al. Nonleaching bacteria-responsive antibacterial surface based on a unique hierarchical architecture
Hadjesfandiari et al. Polymer brush-based approaches for the development of infection-resistant surfaces
CN114040785B (zh) 具有延长抗微生物活性的透明质酸水凝胶
JP4503825B2 (ja) 生物学的組織において癒着の形成を防止するための方法および組成物
US11471558B2 (en) Polypeptide and hyaluronic acid coatings
US20080292675A1 (en) Antimicrobial medicotechnical product, process for its production and use
JP2009526862A5 (https=)
Yu et al. Rapid assembly of infection-resistant coatings: Screening and identification of antimicrobial peptides works in cooperation with an antifouling background
JP2004520088A (ja) 薬剤混和マトリックス
JP6518198B2 (ja) 薬物放出のための化合物及び組成物
US8858972B2 (en) Antimicrobial medicotechnical product, process for its preparation and use
US20240301218A1 (en) Polymeric Antifouling Coating with Antimicrobial Peptides
WO2005006938A2 (en) Anti-microbial medical implants and uses thereof
CN108473632A (zh) 聚合组合物
Khoo et al. Novel infection-resistant surface coatings: A bioengineering approach
US11602578B2 (en) Crosslinkable polypeptide and hyaluronic acid coatings
CA2286687A1 (en) Collagen-like polymers with cell binding activity
JP5222129B2 (ja) 特にスペーサー分子を介してｓ−ｓ架橋により結合することによって基材に共有結合したシステイン化合物を含む抗菌剤
Lawson Structure-function relationships of polymerizable vancomycin derivatives for the antimicrobial surface modification of orthopedic biomaterials

Legal Events

Date Code Title Description
EEER Examination request
FZDE Dead