CA2648915A1 - Tetramerizing polypeptides and methods of use - Google Patents

Tetramerizing polypeptides and methods of use Download PDF

Info

Publication number
CA2648915A1
CA2648915A1 CA002648915A CA2648915A CA2648915A1 CA 2648915 A1 CA2648915 A1 CA 2648915A1 CA 002648915 A CA002648915 A CA 002648915A CA 2648915 A CA2648915 A CA 2648915A CA 2648915 A1 CA2648915 A1 CA 2648915A1
Authority
CA
Canada
Prior art keywords
protein
vasp
cells
heterologous
fusion protein
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002648915A
Other languages
English (en)
French (fr)
Inventor
James W. West
Cameron S. Brandt
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zymogenetics Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2648915A1 publication Critical patent/CA2648915A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503Immunoglobulin superfamily
    • C07K14/70532B7 molecules, e.g. CD80, CD86
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/02Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Toxicology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
CA002648915A 2006-04-13 2007-04-13 Tetramerizing polypeptides and methods of use Abandoned CA2648915A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US79162606P 2006-04-13 2006-04-13
US60/791,626 2006-04-13
PCT/US2007/066607 WO2007124283A2 (en) 2006-04-13 2007-04-13 Tetramerizing polypeptides and methods of use

Publications (1)

Publication Number Publication Date
CA2648915A1 true CA2648915A1 (en) 2007-11-01

Family

ID=38617337

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002648915A Abandoned CA2648915A1 (en) 2006-04-13 2007-04-13 Tetramerizing polypeptides and methods of use

Country Status (7)

Country Link
US (1) US20070254339A1 (https=)
EP (1) EP2004682A2 (https=)
JP (1) JP2009538120A (https=)
AU (1) AU2007240491A1 (https=)
CA (1) CA2648915A1 (https=)
IL (1) IL194161A0 (https=)
WO (1) WO2007124283A2 (https=)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5401001B2 (ja) 2002-09-11 2014-01-29 ジェネンテック, インコーポレイテッド 免疫関連疾患の治療のための新規組成物と方法
US8216996B2 (en) 2006-03-03 2012-07-10 Ono Pharmaceutical Co., Ltd. Multimer of extracellular domain of cell surface functional molecule
WO2007121364A2 (en) * 2006-04-13 2007-10-25 Zymogenetics, Inc. Tetramerizing polypeptides and methods of use
CN102099055A (zh) 2007-10-04 2011-06-15 津莫吉尼蒂克斯公司 B7家族成员zB7H6及相关的组合物和方法
SG10202112838YA (en) 2008-04-09 2021-12-30 Genentech Inc Novel compositions and methods for the treatment of immune related diseases
US8822642B2 (en) 2010-06-09 2014-09-02 Zymogenetics, Inc. Dimeric fusion proteins and related compositions and methods
BR112016000853A2 (pt) 2013-07-16 2017-12-12 Genentech Inc métodos para tratar ou retardar, reduzir ou inibir a recidiva ou a progressão do câncer e a progressão de uma doença imune-relacionada em um indivíduo, para aumentar, melhorar ou estimular uma resposta ou função imune em um indivíduo e kit
US10550173B2 (en) 2015-02-19 2020-02-04 Compugen, Ltd. PVRIG polypeptides and methods of treatment
DK3653221T5 (da) 2015-02-19 2024-08-26 Compugen Ltd Anti-pvrig-antistoffer og anvendelsesfremgangsmåder
PE20181046A1 (es) 2015-09-25 2018-07-03 Genentech Inc Anticuerpos anti-tigit y metodos de uso
CN106565836B (zh) * 2015-10-10 2020-08-18 中国科学院广州生物医药与健康研究院 高亲和力的可溶性pdl-1分子
US10537633B2 (en) 2016-03-04 2020-01-21 Jn Biosciences Llc Antibodies to TIGIT
IL317989A (en) 2016-08-17 2025-02-01 Compugen Ltd Anti-TIGIT antibodies, anti-PVRIG antibodies and combinations thereof
EP3606949A1 (en) * 2017-04-06 2020-02-12 Universität Stuttgart Tumor necrosis factor receptor (tnfr) binding protein complex with improved binding and bioactivity
JP7348072B2 (ja) 2017-06-01 2023-09-20 コンピュジェン リミテッド 三重併用抗体療法
JP2021534196A (ja) 2018-08-23 2021-12-09 シージェン インコーポレイテッド 抗tigit抗体
AU2020301529B2 (en) 2019-06-24 2026-03-26 Universität Stuttgart TNFR2 agonists with improved stability
MX2022015157A (es) 2020-06-02 2023-01-16 Arcus Biosciences Inc Anticuerpos para tigit.

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6803192B1 (en) * 1999-11-30 2004-10-12 Mayo Foundation For Medical Education And Research B7-H1, a novel immunoregulatory molecule
ATE532860T1 (de) * 2000-09-20 2011-11-15 Amgen Inc B7-ähnliche moleküle und deren anwendungen
EP2311960A3 (en) * 2001-08-29 2011-06-01 Genentech, Inc. Bv8 nucleic acids and polypeptides with mitogenic activity
US7193069B2 (en) * 2002-03-22 2007-03-20 Research Association For Biotechnology Full-length cDNA
JP5401001B2 (ja) * 2002-09-11 2014-01-29 ジェネンテック, インコーポレイテッド 免疫関連疾患の治療のための新規組成物と方法
EP1891107B1 (en) * 2005-05-12 2011-07-06 ZymoGenetics, Inc. Compositions and methods for modulating immune responses

Also Published As

Publication number Publication date
US20070254339A1 (en) 2007-11-01
JP2009538120A (ja) 2009-11-05
AU2007240491A1 (en) 2007-11-01
WO2007124283A2 (en) 2007-11-01
IL194161A0 (en) 2011-08-01
WO2007124283A3 (en) 2008-01-17
EP2004682A2 (en) 2008-12-24

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Legal Events

Date Code Title Description
FZDE Discontinued
FZDE Discontinued

Effective date: 20120413